Regions within the N-terminal Domain of Human Topoisomerase I Exert Important Functions during Strand Rotation and DNA Binding

Journal of Molecular Biology

Volumn 336, Issue 1, 2004, Pages 93-103

  Frøhlich, Rikke From ^a   Andersen, Félicie Faucon ^a   Westergaard, Ole ^a   Andersen, Anni Hangaard ^a   Knudsen, Birgitta Ruth ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Camptothecin; Catalysis; Domain function; Human topoisomerase I; Strand rotation

Indexed keywords

AMINO ACID; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DNA FRAGMENT; DNA TOPOISOMERASE; GLYCINE; MUTANT PROTEIN; TRYPTOPHAN;

AMINO TERMINAL SEQUENCE; ARTICLE; DNA BINDING; ENZYME ACTIVITY; HUMAN; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DOMAIN; WILD TYPE;

EID: 0347130921     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2003.12.007     Document Type: Article

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