Mutational analysis of the preferential binding of human topoisomerase i to supercoiled DNA

FEBS Journal

Volumn 276, Issue 20, 2009, Pages 5906-5919

  Yang, Zheng ^a   Carey, James F ^a   Champoux, James J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Competition binding assay; DNA topology; Node binding; Supercoiled DNA; Topoisomerase I

Indexed keywords

DNA; DNA TOPOISOMERASE; GLUTAMIC ACID; LYSINE;

ARTICLE; BINDING ASSAY; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; DNA BINDING; DNA SUPERCOILING; ENZYME BINDING; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL;

DNA MUTATIONAL ANALYSIS; DNA TOPOISOMERASES, TYPE I; DNA, SUPERHELICAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; MODELS, MOLECULAR; MUTATION; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY;

EID: 70349481519     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07270.x     Document Type: Article

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