-
1
-
-
24944583478
-
Targeted modification of mammalian genomes
-
Sorrell DA, Kolb AF (2005) Targeted modification of mammalian genomes. Biotechnol Adv 23(7-8):431-469.
-
(2005)
Biotechnol Adv
, vol.23
, Issue.7-8
, pp. 431-469
-
-
Sorrell, D.A.1
Kolb, A.F.2
-
2
-
-
0343415768
-
Mammalian genomes contain active recombinase recognition sites
-
Thyagarajan B, Guimaraes MJ, Groth AC, Calos MP (2000) Mammalian genomes contain active recombinase recognition sites. Gene 244(1-2):47-54.
-
(2000)
Gene
, vol.244
, Issue.1-2
, pp. 47-54
-
-
Thyagarajan, B.1
Guimaraes, M.J.2
Groth, A.C.3
Calos, M.P.4
-
3
-
-
0034610394
-
Illegitimate Credependent chromosome rearrangements in transgenic mouse spermatids
-
Schmidt EE, Taylor DS, Prigge JR, Barnett S, Capecchi MR (2000) Illegitimate Credependent chromosome rearrangements in transgenic mouse spermatids. Proc Natl Acad Sci USA 97:13702-13707.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13702-13707
-
-
Schmidt, E.E.1
Taylor, D.S.2
Prigge, J.R.3
Barnett, S.4
Capecchi, M.R.5
-
4
-
-
0035979247
-
Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells
-
Loonstra A, et al. (2001) Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells. Proc Natl Acad Sci USA 98:9209-9214.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9209-9214
-
-
Loonstra, A.1
-
5
-
-
33746124221
-
PhiC31 integrase induces chromosomal aberrations in primary human fibroblasts
-
Liu J, Jeppesen I, Nielsen K, Jensen TG (2006) PhiC31 integrase induces chromosomal aberrations in primary human fibroblasts. Gene Therapy 13:1188-1190.
-
(2006)
Gene Therapy
, vol.13
, pp. 1188-1190
-
-
Liu, J.1
Jeppesen, I.2
Nielsen, K.3
Jensen, T.G.4
-
6
-
-
33644767178
-
Integration specificity of phage phiC31 integrase in the human genome
-
Chalberg TW, et al. (2006) Integration specificity of phage phiC31 integrase in the human genome. J Mol Biol 357:28-48.
-
(2006)
J Mol Biol
, vol.357
, pp. 28-48
-
-
Chalberg, T.W.1
-
7
-
-
33847363901
-
Evolution of programmable zinc finger-recombinases with activity in human cells
-
Gordley RM, Smith JD, Graslund T, BarbasCF, III (2007) Evolution of programmable zinc finger-recombinases with activity in human cells. J Mol Biol 367:802-813.
-
(2007)
J Mol Biol
, vol.367
, pp. 802-813
-
-
Gordley, R.M.1
Smith, J.D.2
Graslund, T.3
BarbasCF III4
-
9
-
-
0024195388
-
Isolation and characterization of unusual gin mutants
-
Klippel A, Cloppenborg K, Kahmann R (1988) Isolation and characterization of unusual gin mutants. EMBO J 7:3983-3989.
-
(1988)
EMBO J
, vol.7
, pp. 3983-3989
-
-
Klippel, A.1
Cloppenborg, K.2
Kahmann, R.3
-
10
-
-
0033105367
-
Mutants of Tn3 resolvase which do not require accessory binding sites for recombination activity
-
Arnold PH, Blake DG, Grindley ND, Boocock MR, Stark WM (1999) Mutants of Tn3 resolvase which do not require accessory binding sites for recombination activity. EMBO J 18:1407-1414.
-
(1999)
EMBO J
, vol.18
, pp. 1407-1414
-
-
Arnold, P.H.1
Blake, D.G.2
Grindley, N.D.3
Boocock, M.R.4
Stark, W.M.5
-
11
-
-
0028949096
-
Cin-mediated recombination at secondary crossover sites on the Escherichia coli chromosome
-
Rozsa FW, Viollier P, Fussenegger M, Hiestand-Nauer R, Arber W (1995) Cin-mediated recombination at secondary crossover sites on the Escherichia coli chromosome. J Bacteriol 177:1159-1168.
-
(1995)
J Bacteriol
, vol.177
, pp. 1159-1168
-
-
Rozsa, F.W.1
Viollier, P.2
Fussenegger, M.3
Hiestand-Nauer, R.4
Arber, W.5
-
12
-
-
0029127032
-
Crystal structure of the site-specific recombinase gamma delta resolvase complexed with a 34 bp cleavage site
-
SteitzTA
-
Yang W, SteitzTA (1995) Crystal structure of the site-specific recombinase gamma delta resolvase complexed with a 34 bp cleavage site. Cell 82:193-207.
-
(1995)
Cell
, vol.82
, pp. 193-207
-
-
Yang, W.1
-
13
-
-
0037083987
-
Testing water-mediated DNA recognition by the Hin recombinase
-
Chiu TK, Sohn C, Dickerson RE, Johnson RC (2002) Testing water-mediated DNA recognition by the Hin recombinase. EMBO J 21:801-814.
-
(2002)
EMBO J
, vol.21
, pp. 801-814
-
-
Chiu, T.K.1
Sohn, C.2
Dickerson, R.E.3
Johnson, R.C.4
-
14
-
-
33749155924
-
Structure of Aart, a designed six-finger zinc finger peptide, bound to DNA
-
Segal DJ, Crotty JW, Bhakta MS, Barbas CF, III, Horton NC (2006) Structure of Aart, a designed six-finger zinc finger peptide, bound to DNA. J Mol Biol 363:405-421.
-
(2006)
J Mol Biol
, vol.363
, pp. 405-421
-
-
Segal, D.J.1
Crotty, J.W.2
Bhakta, M.S.3
Barbas III, C.F.4
Horton, N.C.5
-
15
-
-
0034923498
-
Design and selection of novel Cys2His2 zinc finger proteins
-
Pabo CO, Peisach E, Grant RA (2001) Design and selection of novel Cys2His2 zinc finger proteins. Ann Rev Biochem 70:313-340.
-
(2001)
Ann Rev Biochem
, vol.70
, pp. 313-340
-
-
Pabo, C.O.1
Peisach, E.2
Grant, R.A.3
-
16
-
-
47349097567
-
Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification
-
Maeder ML, et al. (2008) Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification. Mol Cell 31:294-301.
-
(2008)
Mol Cell
, vol.31
, pp. 294-301
-
-
Maeder, M.L.1
-
17
-
-
0036168937
-
Engineering polydactyl zinc-finger transcription factors
-
Beerli RR & Barbas CF, III (2002) Engineering polydactyl zinc-finger transcription factors. Nat Biotechnol 20:135-141.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 135-141
-
-
Beerli, R.R.1
Barbas III, C.F.2
-
18
-
-
0034652141
-
-
Beerli RR, DreierB, BarbasCF, III (2000) Positive and negative regulation of endogenous genes by designed transcription factors. Proc Natl Acad Sci USA 97:1495-1500.
-
Beerli RR, DreierB, BarbasCF, III (2000) Positive and negative regulation of endogenous genes by designed transcription factors. Proc Natl Acad Sci USA 97:1495-1500.
-
-
-
-
19
-
-
0142027810
-
Zinc-finger protein-targeted gene regulation: Genomewide singlegene specificity
-
Tan S, etal. (2003) Zinc-finger protein-targeted gene regulation: Genomewide singlegene specificity. Proc Natl Acad Sci USA 100:11997-12002.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 11997-12002
-
-
Tan, S.1
-
20
-
-
0037452614
-
Inhibition of herpes simplex virus 1 gene expression by designer zinc-finger transcription factors
-
Papworth M, et al. (2003) Inhibition of herpes simplex virus 1 gene expression by designer zinc-finger transcription factors. Proc Natl Acad Sci USA 100:1621-1626.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1621-1626
-
-
Papworth, M.1
-
21
-
-
33644774584
-
Inhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primerbinding site
-
Eberhardy SR, et al. (2006) Inhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primerbinding site. J Virol 80:2873-2883.
-
(2006)
J Virol
, vol.80
, pp. 2873-2883
-
-
Eberhardy, S.R.1
-
22
-
-
18944373328
-
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
-
Urnov FD, et al. (2005) Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature 435:646-651.
-
(2005)
Nature
, vol.435
, pp. 646-651
-
-
Urnov, F.D.1
-
23
-
-
46949095221
-
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
-
Perez EE, et al. (2008) Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases. Nat Biotechnol 26:808-816.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 808-816
-
-
Perez, E.E.1
-
24
-
-
44449120801
-
Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases
-
Santiago Y, et al. (2008) Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases. Proc Natl Acad Sci USA 105:5809-5814.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 5809-5814
-
-
Santiago, Y.1
-
26
-
-
32444434997
-
Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells
-
Tan W, Dong Z, Wilkinson TA, Barbas CF, III, Chow SA (2006) Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells. J Virol 80:1939-1948.
-
(2006)
J Virol
, vol.80
, pp. 1939-1948
-
-
Tan, W.1
Dong, Z.2
Wilkinson, T.A.3
Barbas III, C.F.4
Chow, S.A.5
-
27
-
-
34249339431
-
Targeted Sleeping Beauty transposition in human cells
-
Ivics Z, et al. (2007) Targeted Sleeping Beauty transposition in human cells. Mol Ther 15:1137-1144.
-
(2007)
Mol Ther
, vol.15
, pp. 1137-1144
-
-
Ivics, Z.1
-
28
-
-
34548395961
-
In vivo site-specific DNA methylation with a designed sequence-enabled DNA methylase
-
Nomura W, Barbas CF, III (2007) In vivo site-specific DNA methylation with a designed sequence-enabled DNA methylase. J Am Chem Soc 129:8676-8677.
-
(2007)
J Am Chem Soc
, vol.129
, pp. 8676-8677
-
-
Nomura, W.1
Barbas III, C.F.2
-
29
-
-
55549129245
-
Progress and prospects: Zinc-finger nucleases as gene therapy agents
-
Carroll D (2008) Progress and prospects: Zinc-finger nucleases as gene therapy agents. Gene Therapy 15:1463-1468.
-
(2008)
Gene Therapy
, vol.15
, pp. 1463-1468
-
-
Carroll, D.1
-
30
-
-
0026756197
-
Genomic targeting with a positive-selection lox integration vector allows highly reproducible gene expression in mammalian cells
-
FukushigeS, SauerB (1992) Genomic targeting with a positive-selection lox integration vector allows highly reproducible gene expression in mammalian cells. Proc Natl Acad Sci USA 89:7905-7909.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7905-7909
-
-
Fukushige, S.1
Sauer, B.2
-
31
-
-
0035008830
-
Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase
-
Thyagarajan B, Olivares EC, Hollis RP, Ginsburg DS, Calos MP (2001) Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase. Mol Cell Biol 21:3926-3934.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3926-3934
-
-
Thyagarajan, B.1
Olivares, E.C.2
Hollis, R.P.3
Ginsburg, D.S.4
Calos, M.P.5
-
32
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina S, et al. (2003) LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302:415-419.
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
-
33
-
-
38849103093
-
DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases
-
CornuTI
-
CornuTI, etal. (2008) DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases. Mol Ther 16:352-358.
-
(2008)
Mol Ther
, vol.16
, pp. 352-358
-
-
-
34
-
-
44349168309
-
Heritable gene repression through the action of a directed DNA methyltransferase at a chromosomal locus
-
Smith AE, Hurd PJ, Bannister AJ, Kouzarides T, Ford KG (2008) Heritable gene repression through the action of a directed DNA methyltransferase at a chromosomal locus. J Biol Chem 283:9878-9885.
-
(2008)
J Biol Chem
, vol.283
, pp. 9878-9885
-
-
Smith, A.E.1
Hurd, P.J.2
Bannister, A.J.3
Kouzarides, T.4
Ford, K.G.5
-
35
-
-
0035989649
-
Targeted transgene insertion into human chromosomes by adeno-associated virus vectors
-
Hirata R, Chamberlain J, Dong R, Russell DW (2002) Targeted transgene insertion into human chromosomes by adeno-associated virus vectors. Nat Biotechnol 20:735-738.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 735-738
-
-
Hirata, R.1
Chamberlain, J.2
Dong, R.3
Russell, D.W.4
-
36
-
-
33750060436
-
piggyBacisa flexible and highly active transposonas compared to sleeping beauty, Tol2, and MosI in mammalian cells
-
WuSC
-
WuSC, et al. (2006) piggyBacisa flexible and highly active transposonas compared to sleeping beauty, Tol2, and MosI in mammalian cells. Proc Natl Acad Sci USA 103:15008-15013.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 15008-15013
-
-
-
37
-
-
0022389290
-
Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination
-
Smithies O, Gregg RG, Boggs SS, Koralewski MA, Kucherlapati RS (1985) Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination. Nature 317:230-234.
-
(1985)
Nature
, vol.317
, pp. 230-234
-
-
Smithies, O.1
Gregg, R.G.2
Boggs, S.S.3
Koralewski, M.A.4
Kucherlapati, R.S.5
-
38
-
-
33847246298
-
Meganucleases and DNA double-strand break-induced recombination: Perspectives for gene therapy
-
Paques F, Duchateau P (2007) Meganucleases and DNA double-strand break-induced recombination: Perspectives for gene therapy. Curr Gene Therapy 7:49-66.
-
(2007)
Curr Gene Therapy
, vol.7
, pp. 49-66
-
-
Paques, F.1
Duchateau, P.2
-
39
-
-
17844400537
-
How restriction enzymes became the workhorses of molecular biology
-
Roberts RJ (2005) How restriction enzymes became the workhorses of molecular biology. Proc Natl Acad Sci USA 102:5905-5908.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5905-5908
-
-
Roberts, R.J.1
-
40
-
-
0035800769
-
Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors
-
Dreier B, Beerli RR, Segal DJ, Flippin JD, Barbas CF, III (2001) Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors. J Biol Chem 276:29466-29478.
-
(2001)
J Biol Chem
, vol.276
, pp. 29466-29478
-
-
Dreier, B.1
Beerli, R.R.2
Segal, D.J.3
Flippin, J.D.4
Barbas III, C.F.5
-
41
-
-
27444444925
-
Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors
-
Dreier B, et al. (2005) Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors. J Biol Chem 280:35588-35597.
-
(2005)
J Biol Chem
, vol.280
, pp. 35588-35597
-
-
Dreier, B.1
-
42
-
-
0034602243
-
Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains
-
Dreier B, Segal DJ, Barbas CF, III (2000) Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains. J Mol Biol 303:489-502.
-
(2000)
J Mol Biol
, vol.303
, pp. 489-502
-
-
Dreier, B.1
Segal, D.J.2
Barbas III, C.F.3
-
43
-
-
0025352187
-
Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
-
Morgenstern JP, Land H (1990) Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res 18:3587-3596.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 3587-3596
-
-
Morgenstern, J.P.1
Land, H.2
|