Synthesis of 6-cinnamoyl-2H-benzo[b][1,4]oxazin-3(4H)-ones and their effects on A549 lung cancer cell growth

European Journal of Medicinal Chemistry

Volumn 79, Issue , 2014, Pages 95-101

  Zhou, Xue Wen ^a   Ma, Han Lin ^a   Zhang, Xuan ^a   Jing, Shi Yao ^a   Miao, Jun Ying ^a   Zhao, Bao Xiang ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

A549 lung cells; Autophagy; Benzoxazinone; Chalcone

Indexed keywords

6 CINNAMOYL 2H BENZO[B][1,4]OXAZIN 3 (4H)ONE DERIVATIVE; 6 [3 (2,4 DIMETHOXYPHENYL)ACRYLOYL] 2H BENZO[B][1,4]OXAZIN 3 (4H)ONE; 6 [3 (3,5 DIMETHOXYPHENYL)ACRYLOYL] 2H BENZO[B][1,4]OXAZIN 3 (4H)ONE; 6 [3 (BENZO[D][1,3]DIOXOL 5 YL)ACRYLOYL] 2H BENZO[B][1,4]OXAZIN 3 (4H)ONE; 6 [3 (NAPHTHALEN 2 YL)ACRYLOYL] 2H BENZO[B][1,4]OXAZIN 3 (4H)ONE; 6 [3 [4 (BENZYLOXY)PHENYL]ACRYLOYL] 2H BENZO[B][1,4]OXAZIN 3 (4H)ONE; 6 [3 [4 CHLOROPHENYL)ACRYLOYL] 2H BENZO[B][1,4]OXAZIN 3 (4H)ONE; ANTINEOPLASTIC AGENT; BENZOXAZINONE DERIVATIVE; CHALCONE DERIVATIVE; KETONE DERIVATIVE; UNCLASSIFIED DRUG; 6-CINNAMOYL-2H-BENZO(B)(1,4)OXAZIN-3(4H)-ONE; BENZOXAZINE DERIVATIVE; CINNAMIC ACID DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; CANCER CELL; CELL CYCLE ARREST; CELL GROWTH; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; LUNG CANCER; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY DIFFRACTION; CELL CYCLE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; LUNG TUMOR; PATHOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL CULTURE; X RAY CRYSTALLOGRAPHY;

ANTINEOPLASTIC AGENTS; AUTOPHAGY; BENZOXAZINES; CELL CYCLE; CELL PROLIFERATION; CINNAMATES; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LUNG NEOPLASMS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84898626768     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.03.087     Document Type: Article

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