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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 23, 2013, Pages 6436-6441

Synthesis and anti-parasitic activity of a novel quinolinone-chalcone series

(6) Roussaki, Marina a Hall, Belinda b Lima, Sofia Costa c Da Silva, Anabela Cordeiro c,d Wilkinson, Shane b Detsi, Anastasia a

a NATIONAL TECHNICAL UNIVERSITY OF ATHENS (Greece)

b QUEEN MARY UNIVERSITY OF LONDON (United Kingdom)

c UNIVERSITY OF PORTO (Portugal)

d UNIVERSITY OF PORTO (Portugal)

Author keywords

Antiparasitic activity; Cytotoxicity; L. infantum; Quinolinone chalcones; T. brucei

Indexed keywords

AMPHOTERICIN B; ANTIPROTOZOAL AGENT; CHALCONE DERIVATIVE; MOLECULAR SCAFFOLD; NIFURTIMOX; QUINOLINONE CHALCONE DERIVATIVE; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; LEISHMANIA INFANTUM; MAMMAL CELL; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA BRUCEI;

LEISHMANIA INFANTUM; MAMMALIA; TRYPANOSOMA BRUCEI;

ANTIPARASITIC ACTIVITY; CYTOTOXICITY; L. INFANTUM; QUINOLINONE-CHALCONES; T. BRUCEI;

ANIMALS; ANTIPARASITIC AGENTS; CHALCONE; HUMANS; LEISHMANIA; QUINOLONES; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA BRUCEI BRUCEI;

EID: 84886946961 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.09.047 Document Type: Article

Times cited : (53)

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