Synthesis of some novel chalcones, flavanones and flavones and evaluation of their anti-inflammatory activity

European Journal of Medicinal Chemistry

Volumn 65, Issue , 2013, Pages 51-59

  Bano, Sameena ^a   Javed, Kalim ^a   Ahmad, Shamim ^a   Rathish, I G ^a   Singh, Surender ^b   Chaitanya, M ^c   Arunasree, K M ^c   Alam, M S ^a  

^a HAMDARD UNIVERSITY   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^c UNIVERSITY OF HYDERABAD   (India)

Author keywords

Anti inflammatory; Chalcone; Flavanone; Flavone; Indomethacin; TNF

Indexed keywords

CHALCONE DERIVATIVE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; FLAVANONE DERIVATIVE; FLAVONE DERIVATIVE; INDOMETACIN; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; DRUG SYNTHESIS; EDEMA; ULCER;

EID: 84877860269     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.04.056     Document Type: Article

References (17)

1. The Flavonoids, in: J.B. Harborne (Ed.), Advances in Research Since 1986, Chapman and Hall, London, 1999.
2. M. Marder, A.C. Paladini, Curr. Top. Med. Chem. 2 (2002) 853.
3. P.K. Hyun, K.H. Son, H.W. Chang, S.S. Kang, J. Pharmacol. Sci. 96 (2004) 229.
4. Z. Nowakowska, Eur. J. Med. Chem. 42 (2007) 125.
5. J.A. Manthey, K. Grohmann, N. Guthrie, Curr. Med. Chem. 8 (2001) 135.
6. A. Fournet, V. Muñoz, Curr. Top. Med. Chem. 2 (2002) 1215.
7. Y.-M. Lin, Y. Zhou, M.T. Flavin, L.-M. Zhou, W. Nie, F.-C. Chen, Bioorg. Med. Chem. 10 (2002) 2795.
8. M. Cabrera, M. Simoens, G. Falchi, M.L. Lavaggi, O.E. Piro, E.E. Castellano, A. Vidal, A. Azqueta, A. Monge, A.L. Cerain, G. Sagrera, G. Seoane, H. Cerecetto, M. Gonzalez, Bioorg. Med. Chem. 15 (2007) 3356.
9. C.A. Rice-Evans, N.J. Miller, G. Paganga, Free Radic. Biol. Med. 20 (1996) 933.
10. S.B.A. Ghani, L. Weaver, Z.A. Zidan, H.M. Ali, C.W. Keevil, R.C.D. Brown, Bioorg. Med. Chem. Lett. 18 (2008) 518.
11. K.S.L. Mota, G.E.N. Dias, M.E.F. Pinto, A.L. Ferreira, A.R.M.S. Brito, C.A.H. Lima, J.M.B. Filho, L.M. Batista, Molecules 14 (2009) 979.
12. I.G. Rathish, K. Javed, S. Ahmad, S. Bano, M.S. Alam, K.K. Pillai, S. Singh, Bioorg. Med. Chem. Lett. 19 (2009) 255.
13. R. Bashir, S. Ovais, S. Yaseen, H. Hamid, M.S. Alam, M. Samim, S. Singh, K. Javed, Bioorg. Med. Chem. Lett. 21 (2011) 4115-4368.
14. C.A. Winter, E.A. Risley, G.W. Nuss, Proc. Soc. Exp. Biol. Med. 111 (1962) 544.
15. G. Daidone, B. Maggio, D. Raffa, Eur. J. Med. Chem. 29 (1994) 707-711.
16. J.K. Gierse, C.M. Koboldt, M.C. Waker, K. Siebert, P.C. Isakoson, Biochem. J. 339 (1999) 607.
17. K.V. Parsa, L.P. Ganesan, M.V. Rajaram, M.A. Gavrilin, A. Balagopal, N.P. Mohapatra, M.D. Wewers, L.S. Schlesinger, J.S. Gunn, S. Tridandapani, PLOS Pathog. 2 (2006) e71.