Coumarin chalcone fibrates: A new structural class of lipid lowering agents

European Journal of Medicinal Chemistry

Volumn 64, Issue , 2013, Pages 422-431

  Sashidhara, Koneni V ^a   Palnati, Gopala Reddy ^a   Sonkar, Ravi ^a   Avula, Srinivasa Rao ^a   Awasthi, Chetan ^a   Bhatia, Gitika ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Coumarin chalcone fibrates; Lipid lowering activity; Lipoprotein metabolism; Plasma FFA; Triton model

Indexed keywords

6 [3 [4 (1 CARBOXYETHOXY)PHENYL] 3 OXOPROP 1 ENYL] 8 METHYL 2 OXO 2H CHROMENE 3 CARBOXYLIC ACID; 6 [3 [4 (CARBOXYMETHOXY)PHENYL] 3 OXOPROP 1 ENYL] 8 ISOPROPYL 2 OXO 2H CHROMENE 3 CARBOXYLIC ACID; 8 SEC BUTYL 6 [3 [4 (2 CARBOXYPROPAN 2 YLOXY)PHENYL] 3 OXOPROP 1 ENYL] 2 OXO 2H CHROMENE 3 CARBOXYLIC ACID; 8 SEC BUTYL 6 [3 [4 (CARBOXYMETHOXY)PHENYL] 3 OXOPROP 1 ENYL] 2 OXO 2H CHROMENE 3 CARBOXYLIC ACID; ANTILIPEMIC AGENT; CHALCONE DERIVATIVE; CHOLESTEROL; COUMARIN DERIVATIVE; ETHYL 6 [3 [4 (1 ETHOXY 1 OXOBUTAN 2 YLOXY)PHENYL] 3 OXOPROP 1 ENYL] 8 METHYL 2 OXO 2H CHROMENE 3 CARBOXYLATE; ETHYL 6 [3 [4 (1 ETHOXY 1 OXOPROPAN 2 YLOXY)PHENYL] 3 OXOPROP 1 ENYL] 8 METHYL 2 OXO 2H CHROMENE 3 CARBOXYLATE; ETHYL 6 [3 [4 (1 ETHOXY 2 METHYL 1 OXOPROPAN 2 YLOXY)PHENYL] 3 OXOPROP 1 ENYL] 8 METHYL 2 OXO 2H CHROMENE 3 CARBOXYLATE; ETHYL 6 [3 [4 (2 ETHOXY 2 OXOETHOXY)PHENYL] 3 OXOPROP 1 ENYL] 8 METHYL 2 OXO 2H CHROMENE 3 CARBOXYLATE; ETHYL 6 [3 [4 (4 ETHOXY 4 OXOBUTOXY)PHENYL] 3 OXOPROP 1 ENYL] 8 METHYL 2 OXO 2H CHROMENE 3 CARBOXYLATE; ETHYL 8 SEC BUTYL 6 [3 [4 (1 ETHOXY 1 OXOPROPAN 2 YLOXY)PHENYL] 3 OXOPROP 1 ENYL] 2 OXO 2H CHROMENE 3-CARBOXYLATE; ETHYL 8 SEC BUTYL 6 [3 [4 (1 ETHOXY 2 METHYL 1 OXOPROPAN 2 YLOXY)PHENYL] 3 OXOPROP 1 ENYL] 2 OXO 2H CHROMENE 3 CARBOXYLIC ACID; ETHYL 8 SEC BUTYL 6 [3 [4 (4 ETHOXY 4 OXOBUTOXY)PHENYL] 3 OXOPROP 1 ENYL] 2 OXO 2H CHROMENE 3 CARBOXYLATE; ETHYL 8 TERT BUTYL 6 [3 [4 (4 ETHOXY 4 OXOBUTOXY)PHENYL] 3 OXOPROP 1 ENYL] 2 OXO 2H CHROMENE 3 CARBOXYLATE; ETHYL2 [4 [3 (3 FORMYL 4 HYDROXY 5 METHYLPHENYL)ACRYLOYL]PHENOXY)PROPANOATE; ETHYL2 [4 [3 (3 SEC BUTYL 5 FORMYL 4 HYDROXYPHENYL)ACRYLOYL]PHENOXY]PROPANOATE; ETHYL6 [3 [4 (2 ETHOXY 2 OXOETHOXY)PHENYL] 3 OXOPROP 1 ENYL] 8 ISOPROPYL 2 OXO 2H CHROMENE 3 CARBOXYLATE; ETHYL8 SEC BUTYL 6 [3 [4 (2 ETHOXY 2 OXOETHOXY)PHENYL] 3 OXOPROP 1 ENYL] 2 OXO 2H CHROMENE 3 CARBOXYLATE; ETHYL8 TERT BUTYL 6 [3 [4 (2 ETHOXY 2 OXOETHOXY)PHENYL] 3 OXOPROP 1 ENYL] 2 OXO 2H CHROMENE 3 CARBOXYLATE; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; TYLOXAPOL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; HYPERLIPIDEMIA; LIPOPROTEIN BLOOD LEVEL; NONHUMAN; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; CHALCONES; COUMARINS; DYSLIPIDEMIAS; MALE; MOLECULAR STRUCTURE; POLYETHYLENE GLYCOLS; RATS; RATS, INBRED STRAINS;

EID: 84877605433     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.04.026     Document Type: Article

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