Tumor-suppressive microRNA-449a induces growth arrest and senescence by targeting E2F3 in human lung cancer cells

Cancer Letters

Volumn 344, Issue 2, 2014, Pages 195-203

  Ren, Xiao Shuai ^a,b   Yin, Meng Hui ^a,b   Zhang, Xin ^c   Wang, Zhe ^a   Feng, Shi Peng ^d   Wang, Guo Xin ^a   Luo, Ying Jun ^d   Liang, Pei Zhou ^a,e   Yang, Xiu Qun ^d   He, Jian Xing ^c   Zhang, Bi Liang ^a,b  

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^c GUANGZHOU MEDICAL UNIVERSITY   (China)

^d Guangzhou Science Park   (China)

^e UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

E2F3; Lung cancer; MiR 449a; Senescence; Survival

Indexed keywords

MICRORNA; MICRORNA 449A; TRANSCRIPTION FACTOR E2F3; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER SURVIVAL; CANCER TISSUE; CELL AGING; CELL CYCLE ARREST; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LUNG CANCER; LUNG CARCINOGENESIS; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN TARGETING; TUMOR SUPPRESSOR GENE;

MUS MUSCULUS;

E2F3; LUNG CANCER; MIR-449A; SENESCENCE; SURVIVAL;

ANIMALS; CARCINOGENESIS; CELL AGING; CELL CYCLE CHECKPOINTS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; E2F3 TRANSCRIPTION FACTOR; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; MIDDLE AGED; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84893680111     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.10.031     Document Type: Article

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