PX-12 inhibits the growth of A549 lung cancer cells via G2/M phase arrest and ROS-dependent apoptosis

International Journal of Oncology

Volumn 44, Issue 1, 2014, Pages 301-308

  You, Bo Ra ^a   Shin, Hye Rim ^a   Park, Woo Hyun ^a  

^a Chonbuk National University   (South Korea)

Author keywords

Apoptosis; Lung cancer; PX 12; Reactive oxygen species; Thioredoxin

Indexed keywords

1 METHYLPROPYL 2 IMIDAZOLYL DISULFIDE; ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; CASPASE 3 INHIBITOR; CASPASE 8 INHIBITOR; CASPASE INHIBITOR; FLUORESCEIN ISOTHIOCYANATE; GLUTATHIONE; LIPOCORTIN 5; PROTEIN BAX; PROTEIN BCL 2; PX 12; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IC 50; LUNG CANCER; M PHASE CELL CYCLE CHECKPOINT; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; PRIORITY JOURNAL; PROTEIN DEPLETION;

APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; DISULFIDES; G2 PHASE CELL CYCLE CHECKPOINTS; GLUTATHIONE; HUMANS; IMIDAZOLES; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE OXYGEN SPECIES;

EID: 84891939128     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.2152     Document Type: Article

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