-
1
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139:871-890
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
2
-
-
84873050284
-
Regulatory networks defining EMT during cancer initiation and progression
-
De Craene B, Berx G (2013) Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 13(2):97-110
-
(2013)
Nat Rev Cancer
, vol.13
, Issue.2
, pp. 97-110
-
-
De Craene, B.1
Berx, G.2
-
3
-
-
84877928478
-
Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs
-
Lamouille S, Subramanyam D, Blelloch R, Derynck R (2013) Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs. Curr Opin Cell Biol 25:200-207
-
(2013)
Curr Opin Cell Biol
, vol.25
, pp. 200-207
-
-
Lamouille, S.1
Subramanyam, D.2
Blelloch, R.3
Derynck, R.4
-
4
-
-
0028245813
-
Cadherin expression in carcinomas: Role in the formation of cell junctions and the prevention of invasiveness
-
DOI 10.1016/0304-419X(94)90003-5
-
Birchmeier W, Behrens J (1994) Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness. Biochim Biophys Acta 1198(1): 11-26 (Pubitemid 24159061)
-
(1994)
Biochimica et Biophysica Acta - Reviews on Cancer
, vol.1198
, Issue.1
, pp. 11-26
-
-
Birchmeier, W.1
Behrens, J.2
-
5
-
-
84897977206
-
Multilayer control of the EMT master regulators
-
doi:10.1038/onc.2013.128
-
Zheng H, Kang Y (2013) Multilayer control of the EMT master regulators. Oncogene. doi:10.1038/onc.2013.128
-
(2013)
Oncogene
-
-
Zheng, H.1
Kang, Y.2
-
6
-
-
84860389952
-
Epithelial-mesenchymal transition and cancer stem cells: A dangerously dynamic duo in breast cancer progression
-
May CD, Sphyris N, Evans KW, Werden SJ, Guo W, Mani SA (2011) Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression. Breast Cancer Res 13(1):202
-
(2011)
Breast Cancer Res
, vol.13
, Issue.1
, pp. 202
-
-
May, C.D.1
Sphyris, N.2
Evans, K.W.3
Werden, S.J.4
Guo, W.5
Mani, S.A.6
-
7
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
Polyak K, Weinberg RA (2009) Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 9:265-273
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
8
-
-
34249289041
-
Snail, ZEB and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
-
DOI 10.1038/nrc2131, PII NRC2131
-
Peinado H, Olmeda D, Cano A (2007) Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 7(6):415-428 (Pubitemid 46809165)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.6
, pp. 415-428
-
-
Peinado, H.1
Olmeda, D.2
Cano, A.3
-
9
-
-
84869453877
-
E proteins regulate osteoclast maturation and survival
-
Long CL, Berry WL, Zhao Y, Sun XH, Humphrey MB (2012) E proteins regulate osteoclast maturation and survival. J one Miner Res 27(12):2476-2489
-
(2012)
J One Miner Res
, vol.27
, Issue.12
, pp. 2476-2489
-
-
Long, C.L.1
Berry, W.L.2
Zhao, Y.3
Sun, X.H.4
Humphrey, M.B.5
-
10
-
-
84860780042
-
Sim2 prevents entry into the myogenic program by repressing MyoD transcription during limb embryonic myogenesis
-
Havis E, Coumailleau P, Bonnet A, Bismuth K, Bonnin MA, Johnson R, Fan CM, Relaix F, Shi DL, Duprez D (2012) Sim2 prevents entry into the myogenic program by repressing MyoD transcription during limb embryonic myogenesis. Development 139(11):1910-1920
-
(2012)
Development
, vol.139
, Issue.11
, pp. 1910-1920
-
-
Havis, E.1
Coumailleau, P.2
Bonnet, A.3
Bismuth, K.4
Bonnin, M.A.5
Johnson, R.6
Fan, C.M.7
Relaix, F.8
Shi, D.L.9
Duprez, D.10
-
11
-
-
0034051923
-
Generation of neurons by transient expression of neural bHLH proteins in mammalian cells
-
FarahMH, Olson JM, Sucic HB, Hume RI, Tapscott SJ, Turner DL (2000) Generation of neurons by transient expression of neural bHLH proteins in mammalian cells. Development 127(4):693-702 (Pubitemid 30129016)
-
(2000)
Development
, vol.127
, Issue.4
, pp. 693-702
-
-
Farah, M.H.1
Olson, J.M.2
Sucic, H.B.3
Hume, R.I.4
Tapscott, S.J.5
Turner, D.L.6
-
12
-
-
0034471262
-
ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis
-
Norton JD (2000) ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis. J Cell Sci 113(22):3897-3905
-
(2000)
J Cell Sci
, vol.113
, Issue.22
, pp. 3897-3905
-
-
Norton, J.D.1
-
13
-
-
77956646295
-
The role of bHLH genes in ear development and evolution: Revisiting a 10-year-old hypothesis
-
Fritzsch B, Eberl DF, Beisel KW (2010) The role of bHLH genes in ear development and evolution: revisiting a 10-year-old hypothesis. Cell Mol Life Sci 67(18):3089-3099
-
(2010)
Cell Mol Life Sci
, vol.67
, Issue.18
, pp. 3089-3099
-
-
Fritzsch, B.1
Eberl, D.F.2
Beisel, K.W.3
-
14
-
-
84877678816
-
SRY induced TCF21 genome-wide targets and cascade of bHLH factors during Sertoli cell differentiation and male sex determination in rats
-
Bhandari RK, Schinke EN, Haque MM, Sadler-Riggleman I, Skinner MK (2012) SRY induced TCF21 genome-wide targets and cascade of bHLH factors during Sertoli cell differentiation and male sex determination in rats. Biol Reprod 87(6):131
-
(2012)
Biol Reprod
, vol.87
, Issue.6
, pp. 131
-
-
Bhandari, R.K.1
Schinke, E.N.2
Haque, M.M.3
Sadler-Riggleman, I.4
Skinner, M.K.5
-
15
-
-
84863242877
-
Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic mice
-
Wang HC, Peng V, Zhao Y, Sun XH (2012) Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic mice. PLoS One 7(2):e32944
-
(2012)
PLoS One
, vol.7
, Issue.2
-
-
Wang, H.C.1
Peng, V.2
Zhao, Y.3
Sun, X.H.4
-
16
-
-
0033980393
-
Helix-loop-helix proteins: Regulators of transcription in eucaryotic organisms
-
DOI 10.1128/MCB.20.2.429-440.2000
-
Massari ME, Murre C (2000) Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms. Mol Cell Biol 20(2):429-440 (Pubitemid 30023084)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.2
, pp. 429-440
-
-
Massari, M.E.1
Murre, C.2
-
17
-
-
4043141372
-
An overview of the basic helix-loop-helix proteins
-
Jones S (2004) An overview of the basic helix-loop-helix proteins. Genome Biol 5(6):226
-
(2004)
Genome Biol
, vol.5
, Issue.6
, pp. 226
-
-
Jones, S.1
-
18
-
-
33947252158
-
Origin and diversification of the basic helix-loop-helix gene family in metazoans: Insights from comparative genomics
-
SimionatoE, Ledent V, Richards G, Thomas-Chollier M,Kerner P, Coornaert D, Degnan BM, Vervoort M (2007) Origin and diversification of the basic helix-loop-helix gene family in metazoans: insights from comparative genomics. BMC Evol Biol 7:33
-
(2007)
BMC Evol Biol
, vol.7
, pp. 33
-
-
Simionato, E.1
Ledent, V.2
Richards, G.3
Thomas-Chollier, M.4
Kerner, P.5
Coornaert, D.6
Degnan, B.M.7
Vervoort, M.8
-
19
-
-
54349102116
-
Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: Genomic approach to cellular differentiation
-
Stevens JD, Roalson EH, Skinner MK (2008) Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation. Differentiation 76:1006-1022
-
(2008)
Differentiation
, vol.76
, pp. 1006-1022
-
-
Stevens, J.D.1
Roalson, E.H.2
Skinner, M.K.3
-
20
-
-
77954144725
-
Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature
-
Skinner MK, Rawls A, Wilson-Rawls J, Roalson EH (2010) Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation 80(1):1-8
-
(2010)
Differentiation
, vol.80
, Issue.1
, pp. 1-8
-
-
Skinner, M.K.1
Rawls, A.2
Wilson-Rawls, J.3
Roalson, E.H.4
-
21
-
-
79960623998
-
The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy
-
Savino M, Annibali D, Carucci N, Favuzzi E, Cole MD, Evan GI, Soucek L, Nasi S (2011) The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy. PLoS One 6(7):e22284
-
(2011)
PLoS One
, vol.6
, Issue.7
-
-
Savino, M.1
Annibali, D.2
Carucci, N.3
Favuzzi, E.4
Cole, M.D.5
Evan, G.I.6
Soucek, L.7
Nasi, S.8
-
22
-
-
77949867499
-
Kinetic analysis of the interaction of b/HLH/Z transcription factors Myc, Max, and Mad with cognate DNA
-
Ecevit O, Khan MA, Goss DJ (2010) Kinetic analysis of the interaction of b/HLH/Z transcription factors Myc, Max, and Mad with cognate DNA. Biochemistry 49(12):2627-2635
-
(2010)
Biochemistry
, vol.49
, Issue.12
, pp. 2627-2635
-
-
Ecevit, O.1
Khan, M.A.2
Goss, D.J.3
-
23
-
-
80052919716
-
USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma
-
Williams SA, Maecker HL, French DM, Liu J, Gregg A, Silverstein LB, Cao TC, Carano RA, Dixit VM (2011) USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma. Cell 146(6):918-930
-
(2011)
Cell
, vol.146
, Issue.6
, pp. 918-930
-
-
Williams, S.A.1
Maecker, H.L.2
French, D.M.3
Liu, J.4
Gregg, A.5
Silverstein, L.B.6
Cao, T.C.7
Carano, R.A.8
Dixit, V.M.9
-
24
-
-
34547922380
-
Delta-Notch-and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors
-
DOI 10.1093/nar/gkm477
-
Fischer A, Gessler M (2007) Delta-Notch-and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors. Nucleic Acids Res 35(14):4583-4596 (Pubitemid 47250333)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.14
, pp. 4583-4596
-
-
Fischer, A.1
Gessler, M.2
-
25
-
-
84873160542
-
Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells
-
Mimeault M, Batra SK (2013) Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells. J Cell Mol Med 17(1):30-54
-
(2013)
J Cell Mol Med
, vol.17
, Issue.1
, pp. 30-54
-
-
Mimeault, M.1
Batra, S.K.2
-
26
-
-
84856739946
-
Hypoxia-inducible factors in physiology and medicine
-
Semenza GL (2012) Hypoxia-inducible factors in physiology and medicine. Cell 148(3):399-408
-
(2012)
Cell
, vol.148
, Issue.3
, pp. 399-408
-
-
Semenza, G.L.1
-
27
-
-
0027215177
-
E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins
-
Bain G, Gruenwald S, Murre C (1993) E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins. Mol Cell Biol 13(6):3522-3529 (Pubitemid 23157290)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.6
, pp. 3522-3529
-
-
Bain, G.1
Gruenwald, S.2
Murre, C.3
-
28
-
-
0031003914
-
Both E12 and E47 allow commitment to the B cell lineage
-
DOI 10.1016/S1074-7613(00)80421-5
-
Bain G, Robanus Maandag EC, te Riele HP, Feeney AJ, Sheehy A, Schlissel M, Shinton SA, Hardy RR, Murre C (1997) Both E12 and E47 allow commitment to the B cell lineage. Immunity 6(2):145-154 (Pubitemid 27145559)
-
(1997)
Immunity
, vol.6
, Issue.2
, pp. 145-154
-
-
Bain, G.1
Robanus, M.E.C.2
Te, R.H.P.J.3
Feeney, A.J.4
Sheehy, A.5
Schlissel, M.6
Shinton, S.A.7
Hardy, R.R.8
Murre, C.9
-
29
-
-
5044248294
-
A role for Id in the regulation of TGF-β-inducedepithelial- mesenchymal transdifferentiation
-
Kondo M, Cubillo E, Tobiume K, Shirakihara T, Fukuda N, Suzuki H, Shimizu K, Takehara K, Cano A, Saitoh M, Miyazono K (2004) A role for Id in the regulation of TGF-β-inducedepithelial-mesenchymal transdifferentiation. Cell Death Differ 11(10):1092-1101
-
(2004)
Cell Death Differ
, vol.11
, Issue.10
, pp. 1092-1101
-
-
Kondo, M.1
Cubillo, E.2
Tobiume, K.3
Shirakihara, T.4
Fukuda, N.5
Suzuki, H.6
Shimizu, K.7
Takehara, K.8
Cano, A.9
Saitoh, M.10
Miyazono, K.11
-
30
-
-
33745861287
-
Overexpression of E2A proteins induces epithelial-mesenchymal transition in human renal proximal tubular epithelial cells suggesting a potential role in renal fibrosis
-
DOI 10.1016/j.febslet.2006.06.039, PII S0014579306007460
-
Slattery C, McMorrow T, Ryan MP (2006) Overexpression of E2A proteins induces epithelial-mesenchymal transition in human renal proximal tubular epithelial cells suggesting a potential role in renal fibrosis. FEBS Lett 580(17):4021-4030 (Pubitemid 44037564)
-
(2006)
FEBS Letters
, vol.580
, Issue.17
, pp. 4021-4030
-
-
Slattery, C.1
McMorrow, T.2
Ryan, M.P.3
-
31
-
-
84875435474
-
E47 and Id1 Interplay in Epithelial-Mesenchymal Transition
-
Cubillo E, Diaz-Lopez A, Cuevas EP, Moreno-Bueno G, Peinado H, Montes A, Santos V, Portillo F, Cano A (2013) E47 and Id1 Interplay in Epithelial-Mesenchymal Transition. PLoS One 8(3):e59948
-
(2013)
PLoS One
, vol.8
, Issue.3
-
-
Cubillo, E.1
Diaz-Lopez, A.2
Cuevas, E.P.3
Moreno-Bueno, G.4
Peinado, H.5
Montes, A.6
Santos, V.7
Portillo, F.8
Cano, A.9
-
32
-
-
33846684874
-
Tubular epithelial cell dedifferentiation is driven by the helix-loop-helix transcriptional inhibitor Id1
-
DOI 10.1681/ASN.2006030236
-
Li Y, Yang J, Luo JH, Dedhar S, Liu Y (2007) Tubular epithelial cell dedifferentiation is driven by the Helix-Loop-Helix transcriptional inhibitor Id1. J Am Soc Nephrol 18(2):449-460 (Pubitemid 46193311)
-
(2007)
Journal of the American Society of Nephrology
, vol.18
, Issue.2
, pp. 449-460
-
-
Li, Y.1
Yang, J.2
Luo, J.-H.3
Dedhar, S.4
Liu, Y.5
-
33
-
-
84881230851
-
Pitt-Hopkins Syndrome: Intellectual disability due to loss of TCF4-regulated gene transcription
-
Sweatt JD (2013) Pitt-Hopkins Syndrome: intellectual disability due to loss of TCF4-regulated gene transcription. Exp Mol Med 45:e21
-
(2013)
Exp Mol Med
, vol.45
-
-
Sweatt, J.D.1
-
34
-
-
66849104147
-
The class I bHLH factors E2-2A and E2-2B regulate EMT
-
Sobrado VR, Moreno-Bueno G, Cubillo E, Holt LJ, Nieto MA, Portillo F, Cano A (2009) The class I bHLH factors E2-2A and E2-2B regulate EMT. J Cell Sci 122:1014-1024
-
(2009)
J Cell Sci
, vol.122
, pp. 1014-1024
-
-
Sobrado, V.R.1
Moreno-Bueno, G.2
Cubillo, E.3
Holt, L.J.4
Nieto, M.A.5
Portillo, F.6
Cano, A.7
-
35
-
-
3242885067
-
Snail and E47 repressors of E-cadherin induce distinct invasive and angiogenic properties in vivo
-
DOI 10.1242/jcs.01145
-
Peinado H, Marin F, Cubillo E, Stark HJ, Fusenig N, Nieto MA, Cano A (2004) Snail and E47 repressors of E-cadherin induce distinct invasive and angiogenic properties in vivo. J Cell Sci 117:2827-2839 (Pubitemid 38997264)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.13
, pp. 2827-2839
-
-
Peinado, H.1
Marin, F.2
Cubillo, E.3
Stark, H.-J.4
Fusenig, N.5
Nieto, M.A.6
Cano, A.7
-
36
-
-
0035920152
-
A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions
-
Perez-Moreno MA, Locascio A, Rodrigo I, Dhondt G, Portillo F, Nieto MA, Cano A (2001) A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions. J Biol Chem 276:27424-27431
-
(2001)
J Biol Chem
, vol.276
, pp. 27424-27431
-
-
Perez-Moreno, M.A.1
Locascio, A.2
Rodrigo, I.3
Dhondt, G.4
Portillo, F.5
Nieto, M.A.6
Cano, A.7
-
37
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
DOI 10.1016/j.cell.2004.06.006, PII S0092867404005768
-
Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C (2004) Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117:927-939 (Pubitemid 38798858)
-
(2004)
Cell
, vol.117
, Issue.7
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
Ramaswamy, S.4
Itzykson, R.A.5
Come, C.6
Savagner, P.7
Gitelman, I.8
Richardson, A.9
Weinberg, R.A.10
-
38
-
-
0026503190
-
Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor
-
Aslakson CJ, Miller FR (1992) Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res 52:1399-1405
-
(1992)
Cancer Res
, vol.52
, pp. 1399-1405
-
-
Aslakson, C.J.1
Miller, F.R.2
-
39
-
-
20444453337
-
Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target
-
DOI 10.1158/0008-5472.CAN-04-3785
-
Kwok WK, Ling MT, Lee TW, Lau TC, Zhou C, Zhang X, Chua CW, Chan KW, Chan FL, Glackin C, Wong YC, Wang X (2005) Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target. Cancer Res 65:5153-5162 (Pubitemid 40827324)
-
(2005)
Cancer Research
, vol.65
, Issue.12
, pp. 5153-5162
-
-
Kwok, W.K.1
Ling, M.-T.2
Lee, T.-W.3
Lau, T.C.M.4
Zhou, C.5
Zhang, X.6
Chua, C.W.7
Chan, K.W.8
Chan, F.L.9
Glackin, C.10
Wong, Y.-C.11
Wang, X.12
-
41
-
-
39449133669
-
Regulation of cancer cell survival, migration, and invasion by twist: AKT2 comes to interplay
-
DOI 10.1158/0008-5472.CAN-07-5067
-
Cheng GZ, Zhang W, Wang LH (2008) Regulation of cancer cell survival, migration, and invasion by Twist: AKT2 comes to interplay. Cancer Res 68:957-960 (Pubitemid 351272210)
-
(2008)
Cancer Research
, vol.68
, Issue.4
, pp. 957-960
-
-
Cheng, G.Z.1
Zhang, W.2
Wang, L.-H.3
-
42
-
-
47249161129
-
Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function
-
Cheng GZ, Zhang WZ, Sun M, Wang Q, Coppola D, Mansour M, Xu LM, Costanzo C, Cheng JQ, Wang LH (2008) Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function. J Biol Chem 283:14665-14673
-
(2008)
J Biol Chem
, vol.283
, pp. 14665-14673
-
-
Cheng, G.Z.1
Zhang, W.Z.2
Sun, M.3
Wang, Q.4
Coppola, D.5
Mansour, M.6
Xu, L.M.7
Costanzo, C.8
Cheng, J.Q.9
Wang, L.H.10
-
43
-
-
65249155400
-
Twist1-mediated adriamycin induced epithelial-mesenchymal transition relates to multidrug resistance and invasive potential in breast cancer cells
-
Li QQ, Xu JD, Wang WJ, Cao XX, Chen Q, Tang F, Chen ZQ, Liu XP, Xu ZD (2009) Twist1-mediated adriamycin induced epithelial-mesenchymal transition relates to multidrug resistance and invasive potential in breast cancer cells. Clin Cancer Res 15:2657-2665
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2657-2665
-
-
Li, Q.Q.1
Xu, J.D.2
Wang, W.J.3
Cao, X.X.4
Chen, Q.5
Tang, F.6
Chen, Z.Q.7
Liu, X.P.8
Xu, Z.D.9
-
44
-
-
79651474948
-
The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis
-
Fu J, Qin L, He T, Qin J, Hong J, Wong J, Liao L, Xu J (2011) The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis. Cell Res 21:275-289
-
(2011)
Cell Res
, vol.21
, pp. 275-289
-
-
Fu, J.1
Qin, L.2
He, T.3
Qin, J.4
Hong, J.5
Wong, J.6
Liao, L.7
Xu, J.8
-
45
-
-
45849087087
-
Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence
-
DOI 10.1016/j.ccr.2008.06.005, PII S1535610808001955
-
Ansieau S, Bastid J, Doreau A, Morel AP, Bouchet BP, Thomas C, Fauvet F, Puisieux I, Doglioni C, Piccinin S, Maestro R, Voeltzel T, Selmi A, Valsesia-Wittmann S, Caron de Fromentel C, Puisieux A (2008) Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence. Cancer Cell 14(1):79-89 (Pubitemid 351890463)
-
(2008)
Cancer Cell
, vol.14
, Issue.1
, pp. 79-89
-
-
Ansieau, S.1
Bastid, J.2
Doreau, A.3
Morel, A.-P.4
Bouchet, B.P.5
Thomas, C.6
Fauvet, F.7
Puisieux, I.8
Doglioni, C.9
Piccinin, S.10
Maestro, R.11
Voeltzel, T.12
Selmi, A.13
Valsesia-Wittmann, S.14
Caron De, F.C.15
Puisieux, A.16
-
46
-
-
67649449918
-
Negative regulation of TIMP1 is mediated by transcription factor TWIST1
-
Okamura H, Yoshida K, Haneji T (2009) Negative regulation of TIMP1 is mediated by transcription factor TWIST1. Int J Oncol 35:181-186
-
(2009)
Int J Oncol
, vol.35
, pp. 181-186
-
-
Okamura, H.1
Yoshida, K.2
Haneji, T.3
-
47
-
-
34247245262
-
MicroRNAs in the search for understanding human diseases
-
DOI 10.2165/00063030-200721020-00004
-
Perera RJ, Ray A (2007) MicroRNAs in the search for understanding human diseases. BioDrugs 21(2):97-104 (Pubitemid 46624554)
-
(2007)
BioDrugs
, vol.21
, Issue.2
, pp. 97-104
-
-
Perera, R.J.1
Ray, A.2
-
48
-
-
72949111146
-
MicroRNA regulation of cancer stem cells and therapeutic implications
-
DeSano JT, Xu L (2009) MicroRNA regulation of cancer stem cells and therapeutic implications. AAPS J 4:682-692
-
(2009)
AAPS J
, vol.4
, pp. 682-692
-
-
DeSano, J.T.1
Xu, L.2
-
49
-
-
35148886434
-
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
-
DOI 10.1038/nature06174, PII NATURE06174
-
Mal L, Teruya-Feldstein J, Weinberg RA (2007) Tumor invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449(7163):682-688 (Pubitemid 47552092)
-
(2007)
Nature
, vol.449
, Issue.7163
, pp. 682-688
-
-
Ma, L.1
Teruya-Feldstein, J.2
Weinberg, R.A.3
-
50
-
-
41849092209
-
MicroRNAs in malignant progression
-
Ma L, Weinberg RA (2008) MicroRNAs in malignant progression. Cell Cycle 7(5):570-572 (Pubitemid 351498993)
-
(2008)
Cell Cycle
, vol.7
, Issue.5
, pp. 570-572
-
-
Ma, L.1
Weinberg, R.A.2
-
51
-
-
77954665205
-
Anti-apoptotic effect of the basic Helix-Loop-Helix (bHLH) transcription factor DEC2 in human breast cancer cells
-
Liu Y, Sato F, Kawamoto T, Fujimoto K, Morohashi S, Akasaka H, Kondo J, Wu Y, Noshiro M, Kato Y, Kijima H (2010) Anti-apoptotic effect of the basic Helix-Loop-Helix (bHLH) transcription factor DEC2 in human breast cancer cells. Genes Cells 15(4):315-325
-
(2010)
Genes Cells
, vol.15
, Issue.4
, pp. 315-325
-
-
Liu, Y.1
Sato, F.2
Kawamoto, T.3
Fujimoto, K.4
Morohashi, S.5
Akasaka, H.6
Kondo, J.7
Wu, Y.8
Noshiro, M.9
Kato, Y.10
Kijima, H.11
-
52
-
-
79952228140
-
Basic Helix-Loop- Helix transcription factors DEC1 and DEC2 regulate the paclitaxel- induced apoptotic pathway of MCF-7 human breast cancer cells
-
Wu Y, Sato F, Bhawal UK, Kawamoto T, Fujimoto K, Noshiro M, Morohashi S, Kato Y, Kijima H (2011) Basic Helix-Loop- Helix transcription factors DEC1 and DEC2 regulate the paclitaxel- induced apoptotic pathway of MCF-7 human breast cancer cells. Int J Mol Med 4:491-495
-
(2011)
Int J Mol Med
, vol.4
, pp. 491-495
-
-
Wu, Y.1
Sato, F.2
Bhawal, U.K.3
Kawamoto, T.4
Fujimoto, K.5
Noshiro, M.6
Morohashi, S.7
Kato, Y.8
Kijima, H.9
-
53
-
-
79958186721
-
Basic Helix-Loop-Helix transcription factor DEC1 negatively regulates cyclin D1
-
Bhawal UK, Sato F, Arakawa Y, Fujimoto K, Kawamoto T, Tanimoto K, Ito Y, Sasahira T, Sakurai T, Kobayashi M, Kashima I, Kijima H, Kuniyasu H, Abiko Y, Kato Y, Sato S (2011) Basic Helix-Loop-Helix transcription factor DEC1 negatively regulates cyclin D1. J Pathol 224(3):420-429
-
(2011)
J Pathol
, vol.224
, Issue.3
, pp. 420-429
-
-
Bhawal, U.K.1
Sato, F.2
Arakawa, Y.3
Fujimoto, K.4
Kawamoto, T.5
Tanimoto, K.6
Ito, Y.7
Sasahira, T.8
Sakurai, T.9
Kobayashi, M.10
Kashima, I.11
Kijima, H.12
Kuniyasu, H.13
Abiko, Y.14
Kato, Y.15
Sato, S.16
-
54
-
-
84866483661
-
The BHLH transcription factor DEC1 plays an important role in the epithelial-mesenchymal transition of pancreatic cancer
-
Wu Y, Sato F, Yamada T, Bhawal UK, Kawamoto T, Fujimoto K, Noshiro M, Seino H, Morohashi S, Hakamada K, Abiko Y, Kato Y, Kijima H (2012) The BHLH transcription factor DEC1 plays an important role in the epithelial-mesenchymal transition of pancreatic cancer. Int J Oncol 41(4):1337-1346
-
(2012)
Int J Oncol
, vol.41
, Issue.4
, pp. 1337-1346
-
-
Wu, Y.1
Sato, F.2
Yamada, T.3
Bhawal, U.K.4
Kawamoto, T.5
Fujimoto, K.6
Noshiro, M.7
Seino, H.8
Morohashi, S.9
Hakamada, K.10
Abiko, Y.11
Kato, Y.12
Kijima, H.13
-
55
-
-
44449144396
-
Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
-
DOI 10.1016/j.devcel.2008.05.009, PII S1534580708002098
-
Yang J, Weinberg RA (2008) Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 14:818-829 (Pubitemid 351757205)
-
(2008)
Developmental Cell
, vol.14
, Issue.6
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
56
-
-
77954759731
-
Hey bHLH factors in cardiovascular development
-
Wiese C, Heisig J, Gessler M (2010) Hey bHLH factors in cardiovascular development. Pediatr Cardiol 31:363-370
-
(2010)
Pediatr Cardiol
, vol.31
, pp. 363-370
-
-
Wiese, C.1
Heisig, J.2
Gessler, M.3
-
57
-
-
79957487931
-
Notch-1 induces epithelial- mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells
-
Bao B, Wang Z, Ali S, Kong D, Li Y, Ahmad A, Banerjee S, Azmi AS, Miele L, Sarkar FH (2011) Notch-1 induces epithelial- mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. Cancer Lett 307(1):26-36
-
(2011)
Cancer Lett
, vol.307
, Issue.1
, pp. 26-36
-
-
Bao, B.1
Wang, Z.2
Ali, S.3
Kong, D.4
Li, Y.5
Ahmad, A.6
Banerjee, S.7
Azmi, A.S.8
Miele, L.9
Sarkar, F.H.10
-
58
-
-
33748171960
-
The c-Myc target gene network
-
DOI 10.1016/j.semcancer.2006.07.014, PII S1044579X06000654, 25 Years of ther c-Myc Oncogene
-
Dang CV, O'Donnell KA, Zeller KI, Nguyen T, Osthus RC, Li F (2006) The c-Myc target gene network. Semin Cancer Biol 16(4):253-264 (Pubitemid 44311039)
-
(2006)
Seminars in Cancer Biology
, vol.16
, Issue.4
, pp. 253-264
-
-
Dang, C.V.1
O'Donnell, K.A.2
Zeller, K.I.3
Nguyen, T.4
Osthus, R.C.5
Li, F.6
-
59
-
-
84874704122
-
C-Myc suppressed E-cadherin through miR-9 at the post-transcriptional level
-
Liu M, Zhu H, Yang S, Wang Z, Bai J, Xu N (2013) C-Myc suppressed E-cadherin through miR-9 at the post-transcriptional level. Cell Biol Int 37(3):197-202
-
(2013)
Cell Biol Int
, vol.37
, Issue.3
, pp. 197-202
-
-
Liu, M.1
Zhu, H.2
Yang, S.3
Wang, Z.4
Bai, J.5
Xu, N.6
-
60
-
-
47249091921
-
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
-
Korpal M, Lee ES, Hu G, Kang Y (2008) The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 283(22):14910-14914
-
(2008)
J Biol Chem
, vol.283
, Issue.22
, pp. 14910-14914
-
-
Korpal, M.1
Lee, E.S.2
Hu, G.3
Kang, Y.4
-
61
-
-
84872744792
-
Tamoxifen represses miR-200 MicroRNAs and promotes epithelial- to-mesenchymal transition by up-regulating c-myc in endometrial carcinoma cell lines
-
Bai JX, Yan B, Zhao ZN, Xiao X, Qin WW, Zhang R, Jia LT, Meng YL, Jin BQ, Fan DM, Wang T, Yang AG (2013) Tamoxifen represses miR-200 MicroRNAs and promotes epithelial- to-mesenchymal transition by up-regulating c-myc in endometrial carcinoma cell lines. Endocrinology 154(2): 635-645
-
(2013)
Endocrinology
, vol.154
, Issue.2
, pp. 635-645
-
-
Bai, J.X.1
Yan, B.2
Zhao, Z.N.3
Xiao, X.4
Qin, W.W.5
Zhang, R.6
Jia, L.T.7
Meng, Y.L.8
Jin, B.Q.9
Fan, D.M.10
Wang, T.11
Yang, A.G.12
-
62
-
-
84867296323
-
c-myc expression and MEK1 induced Erk2 nuclear localization are required for TGFbeta induced epithelial-mesenchymal transition and invasion in prostate cancer
-
Amatangelo MD, Goodyear S, Varma D, Stearns ME (2012) c-myc expression and MEK1 induced Erk2 nuclear localization are required for TGFbeta induced epithelial-mesenchymal transition and invasion in prostate cancer. Carcinogenesis 33(10):1965-1975
-
(2012)
Carcinogenesis
, vol.33
, Issue.10
, pp. 1965-1975
-
-
Amatangelo, M.D.1
Goodyear, S.2
Varma, D.3
Stearns, M.E.4
-
63
-
-
84875882922
-
The enforced expression of c-Myc in pig fibroblasts triggers mesenchymal-epithelial transition (MET) via F-actin reorganization and RhoA/Rock pathway inactivation
-
Shi JW, Liu W, Zhang TT, Wang SC, Lin XL, Li J, Jia JS, Sheng HF, Yao ZF, Zhao WT, Zhao ZL, Xie RY, Yang S, Gao F, Fan QR, Zhang MY, Yue M, Yuan J, Gu WW, Yao KT, Xiao D (2013) The enforced expression of c-Myc in pig fibroblasts triggers mesenchymal-epithelial transition (MET) via F-actin reorganization and RhoA/Rock pathway inactivation. Cell Cycle 12(7):1119-1127
-
(2013)
Cell Cycle
, vol.12
, Issue.7
, pp. 1119-1127
-
-
Shi, J.W.1
Liu, W.2
Zhang, T.T.3
Wang, S.C.4
Lin, X.L.5
Li, J.6
Jia, J.S.7
Sheng, H.F.8
Yao, Z.F.9
Zhao, W.T.10
Zhao, Z.L.11
Xie, R.Y.12
Yang, S.13
Gao, F.14
Fan, Q.R.15
Zhang, M.Y.16
Yue, M.17
Yuan, J.18
Gu, W.W.19
Yao, K.T.20
Xiao, D.21
more..
-
64
-
-
56749184298
-
Reflecting on 25 years with MYC
-
Meyer N, Penn LZ (2008) Reflecting on 25 years with MYC. Nat Rev Cancer 8(12):976-990
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.12
, pp. 976-990
-
-
Meyer, N.1
Penn, L.Z.2
-
66
-
-
77749279644
-
Myc proteins as therapeutic targets
-
Gustafson WC, Weiss WA (2010) Myc proteins as therapeutic targets. Oncogene 29(9):1249-1259
-
(2010)
Oncogene
, vol.29
, Issue.9
, pp. 1249-1259
-
-
Gustafson, W.C.1
Weiss, W.A.2
-
67
-
-
75849131117
-
The ups and downs of Myc biology
-
Soucek L, Evan GI (2010) The ups and downs of Myc biology. Curr Opin Genet Dev 20(1):91-95
-
(2010)
Curr Opin Genet Dev
, vol.20
, Issue.1
, pp. 91-95
-
-
Soucek, L.1
Evan, G.I.2
-
68
-
-
84859171807
-
MYC on the path to cancer
-
Dang CV (2012) MYC on the path to cancer. Cell 149(1):22-35
-
(2012)
Cell
, vol.149
, Issue.1
, pp. 22-35
-
-
Dang, C.V.1
-
69
-
-
0345686714
-
Id-1 as a molecular target in therapy for breast cancer cell invasion and metastasis
-
DOI 10.1073/pnas.2230238100
-
Fong S, Itahana Y, Sumida T, Singh J, Coppe JP, Liu Y, Richards PC, Bennington JL, Lee NM, Debs RJ, Desprez PY (2003) Id-1 as a molecular target in therapy for breast cancer cell invasion and metastasis. Proc Natl Acad Sci USA. 100(23): 13543-13548 (Pubitemid 37444778)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.23
, pp. 13543-13548
-
-
Fong, S.1
Itahana, Y.2
Sumida, T.3
Singh, J.4
Coppe, J.-P.5
Liu, Y.6
Richards, P.C.7
Bennington, J.L.8
Lee, N.M.9
Debs, R.J.10
Desprez, P.-Y.11
-
70
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
DOI 10.1038/nature03799
-
Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD, Viale A, Olshen AB, Gerald WL, Massagué J (2005) Genes that mediate breast cancer metastasis to lung. Nature 436(7050): 518-524 (Pubitemid 41112921)
-
(2005)
Nature
, vol.436
, Issue.7050
, pp. 518-524
-
-
Minn, A.J.1
Gupta, G.P.2
Siegel, P.M.3
Bos, P.D.4
Shu, W.5
Giri, D.D.6
Viale, A.7
Olshen, A.B.8
Gerald, W.L.9
Massague, J.10
-
71
-
-
33845325353
-
Reassessment of Id1 protein expression in human mammary, prostate, and bladder cancers using a monospecific rabbit monoclonal anti-Id1 antibody
-
DOI 10.1158/0008-5472.CAN-06-2643
-
Perk J, Gil-Bazo I, Chin Y, de Candia P, Chen JJ, Zhao Y, Chao S, Cheong W, Ke Y, Al-Ahmadie H, Gerald WL, Brogi E, Benezra R (2006) Reassessment of Id1 protein expression in human mammary, prostate, and bladder cancers using a monospecific rabbit monoclonal anti-id1 antibody. Cancer Res 66(22):10870-10877 (Pubitemid 44876984)
-
(2006)
Cancer Research
, vol.66
, Issue.22
, pp. 10870-10877
-
-
Perk, J.1
Gil-Bazo, I.2
Chin, Y.3
De Candia, P.4
Chen, J.J.S.5
Zhao, Y.6
Chao, S.7
Cheong, W.8
Ke, Y.9
Al-Ahmadie, H.10
Gerald, W.L.11
Brogi, E.12
Benezra, R.13
-
72
-
-
1642327586
-
Id-1 and Id-2 Proteins as Molecular Markers for Human Prostate Cancer Progression
-
DOI 10.1158/1078-0432.CCR-03-0933
-
Coppe JP, Itahana Y, Moore DH, Bennington JL, Desprez PY (2004) Id-1 and Id-2 proteins as molecular markers for human prostate cancer progression. Clin Cancer Res 10(6):2044-2051 (Pubitemid 38375565)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.6
, pp. 2044-2051
-
-
Coppe, J.-P.1
Itahana, Y.2
Moore, D.H.3
Bennington, J.L.4
Desprez, P.-Y.5
-
73
-
-
5044248294
-
A role for Id in the regulation of TGF-beta-induced epithelial- mesenchymal transdifferentiation
-
DOI 10.1038/sj.cdd.4401467
-
Kondo M, Cubillo E, Tobiume K, Shirakihara T, Fukuda N, Suzuki H, Shimizu K, Takehara K, Cano A, Saitoh M, Miyazono K (2004) A role for Id in the regulation of TGF-beta-induced epithelial-mesenchymal transdifferentiation. Cell Death Differ 11(10):1092-1101 (Pubitemid 39341635)
-
(2004)
Cell Death and Differentiation
, vol.11
, Issue.10
, pp. 1092-1101
-
-
Kondo, M.1
Cubillo, E.2
Tobiume, K.3
Shirakihara, T.4
Fukuda, N.5
Suzuki, H.6
Shimizu, K.7
Takehara, K.8
Cano, A.9
Saitoh, M.10
Miyazono, K.11
-
74
-
-
2942536704
-
Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein
-
DOI 10.1128/MCB.24.10.4241-4254.2004
-
Kowanetz M, Valcourt U, Bergstrom R, Heldin CH, Moustakas A (2004) Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein. Mol Cell Biol 24(10):4241-4254 (Pubitemid 41070996)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.10
, pp. 4241-4254
-
-
Kowanetz, M.1
Valcourt, U.2
Bergstrom, R.3
Heldin, C.-H.4
Moustakas, A.5
-
75
-
-
33846684874
-
Tubular epithelial cell dedifferentiation is driven by the helix-loop-helix transcriptional inhibitor Id1
-
DOI 10.1681/ASN.2006030236
-
Li Y, Yang J, Luo JH, Dedhar S, Liu Y (2007) Tubular epithelial cell dedifferentiation is driven by the Helix-Loop-Helix transcriptional inhibitor Id1. J Am Soc Nephrol 18(2):449-460 (Pubitemid 46193311)
-
(2007)
Journal of the American Society of Nephrology
, vol.18
, Issue.2
, pp. 449-460
-
-
Li, Y.1
Yang, J.2
Luo, J.-H.3
Dedhar, S.4
Liu, Y.5
-
76
-
-
0042347689
-
Id proteins in development, cell cycle and cancer
-
DOI 10.1016/S0962-8924(03)00147-8
-
Ruzinova MB, Benezra R (2003) Id proteins in development, cell cycle and cancer. Trends Cell Biol 13(8):410-418 (Pubitemid 36897645)
-
(2003)
Trends in Cell Biology
, vol.13
, Issue.8
, pp. 410-418
-
-
Ruzinova, M.B.1
Benezra, R.2
-
77
-
-
77951953778
-
Epithelial-mesenchymal transition: From molecular mechanisms, redox regulation to implications in human health and disease
-
Cannito S,Novo E, di Bonzo LV, Busletta C, Colombatto S, Parola M (2010) Epithelial-mesenchymal transition: from molecular mechanisms, redox regulation to implications in human health and disease. Antioxid Redox Signal 12(12):1383-1430
-
(2010)
Antioxid Redox Signal
, vol.12
, Issue.12
, pp. 1383-1430
-
-
Cannito, S.1
Novo, E.2
Di Bonzo, L.V.3
Busletta, C.4
Colombatto, S.5
Parola, M.6
-
78
-
-
79954582454
-
Hypoxia predicts aggressive growth and spontaneous metastasis formation from orthotopically grown primary xenografts of human pancreatic cancer
-
Chang Q, Jurisica I, Do T, Hedley DW (2011) Hypoxia predicts aggressive growth and spontaneous metastasis formation from orthotopically grown primary xenografts of human pancreatic cancer. Cancer Res 71(8):3110-3120
-
(2011)
Cancer Res
, vol.71
, Issue.8
, pp. 3110-3120
-
-
Chang, Q.1
Jurisica, I.2
Do, T.3
Hedley, D.W.4
-
79
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify HIF
-
DOI 10.1126/science.1066373
-
Bruick RK, McKnight SL (2001) A conserved family of prolyl- 4-hydroxylases that modify HIF. Science 294(5545):1337-1340 (Pubitemid 33063099)
-
(2001)
Science
, vol.294
, Issue.5545
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
80
-
-
84655161946
-
HIF1a and HIF2a: Sibling rivalry in hypoxic tumour growth and progression
-
Keith B, Johnson RS, Simon MC (2012) HIF1a and HIF2a: sibling rivalry in hypoxic tumour growth and progression. Nat Rev Cancer 12(1):9-22
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.1
, pp. 9-22
-
-
Keith, B.1
Johnson, R.S.2
Simon, M.C.3
-
81
-
-
79954579633
-
EMT: A new vision of hypoxia promoting cancer progression
-
Jiang J, Tang YL, Liang XH (2011) EMT: a new vision of hypoxia promoting cancer progression. Cancer Biol Ther 11(8):714-723
-
(2011)
Cancer Biol Ther
, vol.11
, Issue.8
, pp. 714-723
-
-
Jiang, J.1
Tang, Y.L.2
Liang, X.H.3
-
82
-
-
40249113328
-
Direct regulation of TWIST by HIF-1alpha promotes metastasis
-
Yang MH, Wu MZ, Chiou SH, Chen PM, Chang SY, Liu CJ, Teng SC, Wu KJ (2008) Direct regulation of TWIST by HIF-1alpha promotes metastasis. Nat Cell Biol 10(3):295-305
-
(2008)
Nat Cell Biol
, vol.10
, Issue.3
, pp. 295-305
-
-
Yang, M.H.1
Wu, M.Z.2
Chiou, S.H.3
Chen, P.M.4
Chang, S.Y.5
Liu, C.J.6
Teng, S.C.7
Wu, K.J.8
-
83
-
-
71949128382
-
Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxiainducible factor 1
-
Zhou G, Dada LA, Wu M, Kelly A, Trejo H, Zhou Q, Varga J, Sznajder JI (2009) Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxiainducible factor 1. Am J Physiol Lung Cell Mol Physiol 297(6):L1120-L1130
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
, Issue.6
-
-
Zhou, G.1
Dada, L.A.2
Wu, M.3
Kelly, A.4
Trejo, H.5
Zhou, Q.6
Varga, J.7
Sznajder, J.I.8
-
84
-
-
79956020554
-
Hypoxia and senescence: The impact of oxygenation on tumor suppression
-
Welford SM, Giaccia AJ (2011) Hypoxia and senescence: the impact of oxygenation on tumor suppression. Mol Cancer Res 9(5):538-544
-
(2011)
Mol Cancer Res
, vol.9
, Issue.5
, pp. 538-544
-
-
Welford, S.M.1
Giaccia, A.J.2
-
85
-
-
77954372059
-
Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-beta-dependent mechanisms
-
Copple BL (2010) Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-beta-dependent mechanisms. Liver Int 30(5):669-682
-
(2010)
Liver Int
, vol.30
, Issue.5
, pp. 669-682
-
-
Copple, B.L.1
-
86
-
-
84875790987
-
Hypoxiainducible factor prolyl-hydroxylase-2 mediates transforming growth factor beta 1-induced epithelial-mesenchymal transition in renal tubular cells
-
Han WQ, Zhu Q, Hu J, Li PL, Zhang F, Li N (2013) Hypoxiainducible factor prolyl-hydroxylase-2 mediates transforming growth factor beta 1-induced epithelial-mesenchymal transition in renal tubular cells. Biochim Biophys Acta 1833(6):1454-1462
-
(2013)
Biochim Biophys Acta
, vol.1833
, Issue.6
, pp. 1454-1462
-
-
Han, W.Q.1
Zhu, Q.2
Hu, J.3
Li, P.L.4
Zhang, F.5
Li, N.6
-
87
-
-
44049090235
-
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
-
DOI 10.1073/pnas.0802047105
-
Sahlgren C, Gustafsson MV, Jin S, Poellinger L, Lendahl U (2008) Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Proc Natl Acad Sci USA 105(17):6392-6397 (Pubitemid 351758356)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.17
, pp. 6392-6397
-
-
Sahlgren, C.1
Gustafsson, M.V.2
Jin, S.3
Poellinger, L.4
Lendahl, U.5
-
88
-
-
33646365644
-
Lysyl oxidase is essential for hypoxia-induced metastasis
-
Erler JT, Bennewith KL, Nicolau M, Dornhofer N, Kong C, Le QT, Chi JT, Jeffrey SS, Giaccia AJ (2006) Lysyl oxidase is essential for hypoxia-induced metastasis. Nature 440(7088): 1222-1226
-
(2006)
Nature
, vol.440
, Issue.7088
, pp. 1222-1226
-
-
Erler, J.T.1
Bennewith, K.L.2
Nicolau, M.3
Dornhofer, N.4
Kong, C.5
Le, Q.T.6
Chi, J.T.7
Jeffrey, S.S.8
Giaccia, A.J.9
-
89
-
-
77449108417
-
VEGF elicits epithelial-mesenchymal transition (EMT) in prostate intraepithelial neoplasia (PIN)-like cells via an autocrine loop
-
Gonzalez-Moreno O, Lecanda J, Green JE, Segura V, Catena R, Serrano D, Calvo A (2010) VEGF elicits epithelial-mesenchymal transition (EMT) in prostate intraepithelial neoplasia (PIN)-like cells via an autocrine loop. Exp Cell Res 316(4): 554-567
-
(2010)
Exp Cell Res
, vol.316
, Issue.4
, pp. 554-567
-
-
Gonzalez-Moreno, O.1
Lecanda, J.2
Green, J.E.3
Segura, V.4
Catena, R.5
Serrano, D.6
Calvo, A.7
-
90
-
-
77950476293
-
ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: Implications for Gleason grading
-
Mak P, Leav I, Pursell B, Bae D, Yang X, Taglienti CA, Gouvin LM, Sharma VM, Mercurio AM (2010) ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading. Cancer Cell 17(4):319-332
-
(2010)
Cancer Cell
, vol.17
, Issue.4
, pp. 319-332
-
-
Mak, P.1
Leav, I.2
Pursell, B.3
Bae, D.4
Yang, X.5
Taglienti, C.A.6
Gouvin, L.M.7
Sharma, V.M.8
Mercurio, A.M.9
-
91
-
-
84857147817
-
Hypoxia-induced down-regulation of microRNA- 34a promotes EMT by targeting the Notch signaling pathway in tubular epithelial cells
-
Du R, Sun W, Xia L, Zhao A, Yu Y, Zhao L, Wang H, Huang C, Sun S (2012) Hypoxia-induced down-regulation of microRNA- 34a promotes EMT by targeting the Notch signaling pathway in tubular epithelial cells. PLoS One 7(2):e30771
-
(2012)
PLoS One
, vol.7
, Issue.2
-
-
Du, R.1
Sun, W.2
Xia, L.3
Zhao, A.4
Yu, Y.5
Zhao, L.6
Wang, H.7
Huang, C.8
Sun, S.9
-
92
-
-
0037125916
-
- mice
-
- mice. Curr Biol 12:1601-1604
-
(2002)
Curr Biol
, vol.12
, pp. 1601-1604
-
-
Gessler, M.1
Knobeloch, K.P.2
Helisch, A.3
Amann, K.4
Schumacher, N.5
Rohde, E.6
Fischer, A.7
Leimeister, C.8
-
93
-
-
0037058935
-
Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/HEY2
-
DOI 10.1073/pnas.252648999
-
Sakata Y, Kamei CN, Nakagami H, Bronson R, Liao JK, Chin MT (2002) Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2. Proc Natl Acad Sci USA 99:16197-16202 (Pubitemid 35462772)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.25
, pp. 16197-16202
-
-
Sakata, Y.1
Kamei, C.N.2
Nakagami, H.3
Bronson, R.4
Liao, J.K.5
Chin, M.T.6
-
94
-
-
34147096361
-
Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition
-
DOI 10.1161/01.RES.0000260913.95642.3b
-
Fischer A, Steidl C, Wagner TU, Lang E, Jakob PM, Friedl P, Knobeloch KP, Gessler M (2007) Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition. Circ Res 100:856-863 (Pubitemid 46555691)
-
(2007)
Circulation Research
, vol.100
, Issue.6
, pp. 856-863
-
-
Fischer, A.1
Steidl, C.2
Wagner, T.U.3
Lang, E.4
Jakob, P.M.5
Friedl, P.6
Knobeloch, K.-P.7
Gessler, M.8
-
95
-
-
84872899556
-
The mesenchymal architecture of the cranial mesoderm of mouse embryos is disrupted by the loss of Twist1 function
-
Bildsoe Heidi, Loebel David AF, Jones Vanessa J, Hor Angelyn CC, Braithwaite Antony W, Chen You-Tzung, Behringer Richard R, Tama Patrick PL (2013) The mesenchymal architecture of the cranial mesoderm of mouse embryos is disrupted by the loss of Twist1 function. Dev Biol 374(2):295-307
-
(2013)
Dev Biol
, vol.374
, Issue.2
, pp. 295-307
-
-
Bildsoe, H.1
Loebel, D.A.F.2
Jones, V.J.3
Hor, A.C.C.4
Braithwaite, A.W.5
Chen, Y.-T.6
Behringer, R.R.7
Tama, P.P.L.8
-
96
-
-
48949115598
-
An absence of Twist1 results in aberrant cardiac neural crest morphogenesis
-
Vincentz JW, Barnes RM, Rodgers R, Firulli BA, Conway SJ, Firulli AB (2008) An absence of Twist1 results in aberrant cardiac neural crest morphogenesis. Dev Biol 320(1):131-139
-
(2008)
Dev Biol
, vol.320
, Issue.1
, pp. 131-139
-
-
Vincentz, J.W.1
Barnes, R.M.2
Rodgers, R.3
Firulli, B.A.4
Conway, S.J.5
Firulli, A.B.6
-
97
-
-
84864067904
-
Pod1/Tcf21 is regulated by retinoic acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the developing heart
-
Braitsch CM, Combs MD, Quaggin SE, Yutzey KE (2012) Pod1/Tcf21 is regulated by retinoic acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the developing heart. Dev Biol 368(2):345-357
-
(2012)
Dev Biol
, vol.368
, Issue.2
, pp. 345-357
-
-
Braitsch, C.M.1
Combs, M.D.2
Quaggin, S.E.3
Yutzey, K.E.4
-
98
-
-
84861394103
-
The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors
-
Acharya A, Baek ST, Huang G, Eskiocak B, Goetsch S, Sung CY, Banfi S, Sauer MF, Olsen GS, Duffield JS, Olson EN, Tallquist MD (2012) The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors. Development 139(12):2139-2149
-
(2012)
Development
, vol.139
, Issue.12
, pp. 2139-2149
-
-
Acharya, A.1
Baek, S.T.2
Huang, G.3
Eskiocak, B.4
Goetsch, S.5
Sung, C.Y.6
Banfi, S.7
Sauer, M.F.8
Olsen, G.S.9
Duffield, J.S.10
Olson, E.N.11
Tallquist, M.D.12
-
99
-
-
0033393087
-
The basic-helix-loop-helix protein Pod1 is critically important for kidney and lung organogenesis
-
Quaggin SE, Schwartz L, Cui S, Igarashi P, Deimling J, Post M, Rossant J (1999) The basic-Helix-Loop-Helix protein Pod1 is critically important for kidney and lung organogenesis. Development 126(24):5771-5783 (Pubitemid 30035024)
-
(1999)
Development
, vol.126
, Issue.24
, pp. 5771-5783
-
-
Quaggin, S.E.1
Schwartz, L.2
Cui, S.3
Igarashi, P.4
Deimling, J.5
Post, M.6
Rossant, J.7
-
100
-
-
78650681563
-
Mesp1: A key regulator of cardiovascular lineage commitment
-
Bondue A, Blanpain C (2010) Mesp1: a key regulator of cardiovascular lineage commitment. Circ Res 107(12):1414-1427
-
(2010)
Circ Res
, vol.107
, Issue.12
, pp. 1414-1427
-
-
Bondue, A.1
Blanpain, C.2
-
101
-
-
33845456359
-
Cooperative Mesp activity is required for normal somitogenesis along the anterior-posterior axis
-
DOI 10.1016/j.ydbio.2006.08.043, PII S001216060601133X
-
Morimoto M, Kiso M, Sasaki N, Saga Y (2006) Cooperative Mesp activity is required for normal somitogenesis along the anterior-posterior axis. Dev Biol 300(2):687-698 (Pubitemid 44909103)
-
(2006)
Developmental Biology
, vol.300
, Issue.2
, pp. 687-698
-
-
Morimoto, M.1
Kiso, M.2
Sasaki, N.3
Saga, Y.4
-
102
-
-
48649106835
-
Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs
-
Lindsley RC, Gill JG, Murphy TL, Langer EM, Cai M, Mashayekhi M, Wang W, Niwa N, Nerbonne JM, Kyba M, Murphy KM (2008) Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs. Cell Stem Cell 3(1):55-68
-
(2008)
Cell Stem Cell
, vol.3
, Issue.1
, pp. 55-68
-
-
Lindsley, R.C.1
Gill, J.G.2
Murphy, T.L.3
Langer, E.M.4
Cai, M.5
Mashayekhi, M.6
Wang, W.7
Niwa, N.8
Nerbonne, J.M.9
Kyba, M.10
Murphy, K.M.11
-
103
-
-
40349091380
-
Loss of singleminded-2s in the mouse mammary gland induces an epithelial-mesenchymal transition associated with up-regulation of slug and matrix metalloprotease 2
-
DOI 10.1128/MCB.01701-07
-
Laffin B, Wellberg E, Kwak HI, Burghardt RC, Metz RP, Gustafson T, Schedin P, Porter WW (2008) Loss of singleminded-2 s in the mouse mammary gland induces an epithelial-mesenchymal transition associated with up-regulation of slug and matrix metalloprotease 2. Mol Cell Biol 28(6):1936-1946 (Pubitemid 351342625)
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.6
, pp. 1936-1946
-
-
Laffin, B.1
Wellberg, E.2
Kwak, H.-I.3
Burghardt, R.C.4
Metz, R.P.5
Gustafson, T.6
Schedin, P.7
Porter, W.W.8
-
104
-
-
31144469715
-
Sim1 and Sim2 are required for the correct targeting of mammillary body axons
-
DOI 10.1242/dev.02142
-
Marion JF, Yang C, Caqueret A, Boucher F, Michaud JL (2005) Sim1 and Sim2 are required for the correct targeting of mammillary body axons. Development 132(24):5527-5537 (Pubitemid 43125879)
-
(2005)
Development
, vol.132
, Issue.24
, pp. 5527-5537
-
-
Marion, J.-F.1
Yang, C.2
Caqueret, A.3
Boucher, F.4
Michaud, J.L.5
-
105
-
-
80052470207
-
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
-
Korpal M, Ell BJ, Buffa FM, Ibrahim T, Blanco MA, Celià-Terrassa T, Mercatali L, Khan Z, Goodarzi H, Hua Y, Wei Y, Hu G, Garcia BA, Ragoussis J, Amadori D, Harris AL, Kang Y (2011) Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat Med 17(9):1101-1108
-
(2011)
Nat Med
, vol.17
, Issue.9
, pp. 1101-1108
-
-
Korpal, M.1
Ell, B.J.2
Buffa, F.M.3
Ibrahim, T.4
Blanco, M.A.5
Celià- Terrassa, T.6
Mercatali, L.7
Khan, Z.8
Goodarzi, H.9
Hua, Y.10
Wei, Y.11
Hu, G.12
Garcia, B.A.13
Ragoussis, J.14
Amadori, D.15
Harris, A.L.16
Kang, Y.17
-
106
-
-
84870845421
-
Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis
-
Tsai JH, Donaher JL, Murphy DA, Chau S, Yang J (2012) Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis. Cancer Cell 22(6):725-736
-
(2012)
Cancer Cell
, vol.22
, Issue.6
, pp. 725-736
-
-
Tsai, J.H.1
Donaher, J.L.2
Murphy, D.A.3
Chau, S.4
Yang, J.5
-
107
-
-
33845809125
-
Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: Role of fibroblast growth factor receptor-2
-
DOI 10.1158/0008-5472.CAN-06-2044
-
Chaffer CL, Brennan JP, Slavin JL, Blick T, Thompson EW, Williams ED (2006) Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: role of fibroblast growth factor receptor-2. Cancer Res 66(23):11271-11278 (Pubitemid 46009956)
-
(2006)
Cancer Research
, vol.66
, Issue.23
, pp. 11271-11278
-
-
Chaffer, C.L.1
Brennan, J.P.2
Slavin, J.L.3
Blick, T.4
Thompson, E.W.5
Williams, E.D.6
-
108
-
-
70349645539
-
miR-200 enhances mouse breast cancer cell colonization to form distant metastases
-
Dykxhoorn DM, Wu Y, Xie H, Yu F, Lal A, Petrocca F, Martinvalet D, Song E, Lim B, Lieberman J (2009) miR-200 enhances mouse breast cancer cell colonization to form distant metastases. PLoS One 4(9):e7181
-
(2009)
PLoS One
, vol.4
, Issue.9
-
-
Dykxhoorn, D.M.1
Wu, Y.2
Xie, H.3
Yu, F.4
Lal, A.5
Petrocca, F.6
Martinvalet, D.7
Song, E.8
Lim, B.9
Lieberman, J.10
-
109
-
-
84870816403
-
Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1
-
Ocaña OH, Córcoles R, Fabra A, Moreno-Bueno G, Acloque H, Vega S, Barrallo-Gimeno A, Cano A, Nieto MA(2012) Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1. Cancer Cell 22(6):709-724
-
(2012)
Cancer Cell
, vol.22
, Issue.6
, pp. 709-724
-
-
Ocaña, O.H.1
Córcoles, R.2
Fabra, A.3
Moreno-Bueno, G.4
Acloque, H.5
Vega, S.6
Barrallo-Gimeno, A.7
Cano, A.8
Nieto, M.A.9
-
110
-
-
79955751669
-
Phosphorylation of the Twist1- family basic Helix-Loop-Helix transcription factors is involved in pathological cardiac remodeling
-
Lu S, Nie J, Luan Q, Feng Q, Xiao Q, Chang Z, Shan C, Hess D, Hemmings BA, Yang Z (2011) Phosphorylation of the Twist1- family basic Helix-Loop-Helix transcription factors is involved in pathological cardiac remodeling. PLoS One 6(4):e19251
-
(2011)
PLoS One
, vol.6
, Issue.4
-
-
Lu, S.1
Nie, J.2
Luan, Q.3
Feng, Q.4
Xiao, Q.5
Chang, Z.6
Shan, C.7
Hess, D.8
Hemmings, B.A.9
Yang, Z.10
-
111
-
-
84856253468
-
Phosphorylation of basic helix- loop-helix transcription factor Twist in development and disease
-
Xue G, Hemmings BA (2012) Phosphorylation of basic helix- loop-helix transcription factor Twist in development and disease. Biochem Soc Trans 40(1):90-93
-
(2012)
Biochem Soc Trans
, vol.40
, Issue.1
, pp. 90-93
-
-
Xue, G.1
Hemmings, B.A.2
|