메뉴 건너뛰기




Volumn 12, Issue 7, 2013, Pages 1119-1127

The enforced expression of c-Myc in pig fibroblasts triggers mesenchymal-epithelial transition (MET) via F-actin reorganization and RhoA/Rock pathway inactivation

Author keywords

C Myc; Cytoskeleton reorganization; Dermal fibroblasts; Embryonic fibroblasts; Mesenchymal stem cells; Mesenchymal epithelial transition (MET); RhoA Rock pathway; Tibetan miniature pigs

Indexed keywords

ALPHA CATENIN; CYTOKERATIN; F ACTIN; FIBRONECTIN; MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASE 14; OCCLUDIN; UVOMORULIN; VIMENTIN;

EID: 84875882922     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.24164     Document Type: Article
Times cited : (41)

References (38)
  • 1
    • 84859171807 scopus 로고    scopus 로고
    • MYC on the path to cancer
    • PMID:22464321
    • Dang CV. MYC on the path to cancer. Cell 2012; 149:22-35; PMID:22464321; http://dx.doi. org/10.1016/j.cell.2012.03.003
    • (2012) Cell , vol.149 , pp. 22-35
    • Dang, C.V.1
  • 2
    • 77749279644 scopus 로고    scopus 로고
    • Myc proteins as therapeutic targets
    • PMID:20101214
    • Gustafson WC, Weiss WA. Myc proteins as therapeutic targets. Oncogene 2010; 29:1249-59; PMID:20101214; http://dx.doi.org/10.1038/onc.2009.512
    • (2010) Oncogene , vol.29 , pp. 1249-1259
    • Gustafson, W.C.1    Weiss, W.A.2
  • 3
    • 77449112686 scopus 로고    scopus 로고
    • Key signalling nodes in mammary gland development and cancer: Myc
    • PMID:19849814
    • Hynes NE, Stoelzle T. Key signalling nodes in mammary gland development and cancer: Myc. Breast Cancer Res 2009; 11:210; PMID:19849814; http://dx.doi.org/10.1186/bcr2406
    • (2009) Breast Cancer Res , vol.11 , pp. 210
    • Hynes, N.E.1    Stoelzle, T.2
  • 4
    • 77952576753 scopus 로고    scopus 로고
    • The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy
    • PMID:20382143
    • Larsson LG, Henriksson MA. The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy. Exp Cell Res 2010; 316:1429-37; PMID:20382143; http://dx.doi. org/10.1016/j.yexcr.2010.03.025
    • (2010) Exp Cell Res , vol.316 , pp. 1429-1437
    • Larsson, L.G.1    Henriksson, M.A.2
  • 5
    • 70649105527 scopus 로고    scopus 로고
    • Myc's other life: Stem cells and beyond
    • PMID:19836223
    • Laurenti E, Wilson A, Trumpp A. Myc's other life: stem cells and beyond. Curr Opin Cell Biol 2009; 21:844- 54; PMID:19836223; http://dx.doi.org/10.1016/ j. ceb.2009.09.006
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 844-854
    • Laurenti, E.1    Wilson, A.2    Trumpp, A.3
  • 6
    • 56749184298 scopus 로고    scopus 로고
    • Reflecting on 25 years with MYC
    • PMID:19029958
    • Meyer N, Penn LZ. Reflecting on 25 years with MYC. Nat Rev Cancer 2008; 8:976-90; PMID:19029958; http://dx.doi.org/10.1038/nrc2231
    • (2008) Nat Rev Cancer , vol.8 , pp. 976-990
    • Meyer, N.1    Penn, L.Z.2
  • 7
    • 78649339581 scopus 로고    scopus 로고
    • Myc transcription factors: Key regulators behind establishment and maintenance of pluripotency
    • PMID:21082893
    • Smith K, Dalton S. Myc transcription factors: key regulators behind establishment and maintenance of pluripotency. Regen Med 2010; 5:947- 59; PMID:21082893; http://dx.doi.org/10.2217/rme.10.79
    • (2010) Regen Med , vol.5 , pp. 947-959
    • Smith, K.1    Dalton, S.2
  • 8
    • 75849131117 scopus 로고    scopus 로고
    • The ups and downs of Myc biology
    • PMID:19962879
    • Soucek L, Evan GI. The ups and downs of Myc biology. Curr Opin Genet Dev 2010; 20:91-5; PMID:19962879; http://dx.doi.org/10.1016/j. gde.2009.11.001
    • (2010) Curr Opin Genet Dev , vol.20 , pp. 91-95
    • Soucek, L.1    Evan, G.I.2
  • 9
    • 79951893490 scopus 로고    scopus 로고
    • Myc orchestrates a regulatory network required for the establishment and maintenance of pluripotency
    • PMID:21293186
    • Smith KN, Lim JM, Wells L, Dalton S. Myc orchestrates a regulatory network required for the establishment and maintenance of pluripotency. Cell Cycle 2011; 10:592-7; PMID:21293186; http://dx.doi. org/10.4161/cc.10.4.14792
    • (2011) Cell Cycle , vol.10 , pp. 592-597
    • Smith, K.N.1    Lim, J.M.2    Wells, L.3    Dalton, S.4
  • 10
    • 34249305203 scopus 로고    scopus 로고
    • E-cadherin repression contributes to c-Myc-induced epithelial cell transformation
    • PMID:17146437
    • Cowling VH, Cole MD. E-cadherin repression contributes to c-Myc-induced epithelial cell transformation. Oncogene 2007; 26:3582-6; PMID:17146437; http://dx.doi.org/10.1038/sj.onc.1210132
    • (2007) Oncogene , vol.26 , pp. 3582-3586
    • Cowling, V.H.1    Cole, M.D.2
  • 11
    • 0020520516 scopus 로고
    • Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
    • PMID:6308472
    • Land H, Parada LF, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 1983; 304:596-602; PMID:6308472; http://dx.doi.org/10.1038/304596a0
    • (1983) Nature , vol.304 , pp. 596-602
    • Land, H.1    Parada, L.F.2    Weinberg, R.A.3
  • 12
    • 73149086829 scopus 로고    scopus 로고
    • P21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo
    • PMID:19858489
    • Liu M, Casimiro MC, Wang C, Shirley LA, Jiao X, Katiyar S, et al. p21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo. Proc Natl Acad Sci USA 2009; 106:19035- 9; PMID:19858489; http://dx.doi.org/10.1073/pnas. 0910009106
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 19035-19039
    • Liu, M.1    Casimiro, M.C.2    Wang, C.3    Shirley, L.A.4    Jiao, X.5    Katiyar, S.6
  • 13
    • 38849093994 scopus 로고    scopus 로고
    • Direct evidence for epithelial-mesenchymal transitions in breast cancer
    • PMID:18245497
    • Trimboli AJ, Fukino K, de Bruin A, Wei G, Shen L, Tanner SM, et al. Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Res 2008; 68:937-45; PMID:18245497; http://dx.doi. org/10.1158/0008-5472.CAN-07- 2148
    • (2008) Cancer Res , vol.68 , pp. 937-945
    • Trimboli, A.J.1    Fukino, K.2    De Bruin, A.3    Wei, G.4    Shen, L.5    Tanner, S.M.6
  • 14
    • 0022380768 scopus 로고
    • The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
    • PMID:3906410
    • Adams JM, Harris AW, Pinkert CA, Corcoran LM, Alexander WS, Cory S, et al. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature 1985; 318:533-8; PMID:3906410; http://dx.doi.org/10.1038/318533a0
    • (1985) Nature , vol.318 , pp. 533-538
    • Adams, J.M.1    Harris, A.W.2    Pinkert, C.A.3    Corcoran, L.M.4    Alexander, W.S.5    Cory, S.6
  • 15
    • 38549131395 scopus 로고    scopus 로고
    • AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies
    • PMID:18242516
    • Chesi M, Robbiani DF, Sebag M, Chng WJ, Affer M, Tiedemann R, et al. AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies. Cancer Cell 2008; 13:167-80; PMID:18242516; http://dx.doi.org/10.1016/j.ccr.2008.01.007
    • (2008) Cancer Cell , vol.13 , pp. 167-180
    • Chesi, M.1    Robbiani, D.F.2    Sebag, M.3    Chng, W.J.4    Affer, M.5    Tiedemann, R.6
  • 16
    • 0022497717 scopus 로고
    • Consequences of widespread deregulation of the c-myc gene in transgenic mice: Multiple neoplasms and normal development
    • PMID:3011271
    • Leder A, Pattengale PK, Kuo A, Stewart TA, Leder P. Consequences of widespread deregulation of the c-myc gene in transgenic mice: multiple neoplasms and normal development. Cell 1986; 45:485-95; PMID:3011271; http://dx.doi.org/10.1016/0092- 8674(86)90280-1
    • (1986) Cell , vol.45 , pp. 485-495
    • Leder, A.1    Pattengale, P.K.2    Kuo, A.3    Stewart, T.A.4    Leder, P.5
  • 17
    • 77952490843 scopus 로고    scopus 로고
    • Overexpression of c-myc induces epithelial mesenchymal transition in mammary epithelial cells
    • PMID:20144848
    • Cho KB, Cho MK, Lee WY, Kang KW. Overexpression of c-myc induces epithelial mesenchymal transition in mammary epithelial cells. Cancer Lett 2010; 293:230- 9; PMID:20144848; http://dx.doi.org/10.1016/j.canlet. 2010.01.013
    • (2010) Cancer Lett , vol.293 , pp. 230-239
    • Cho, K.B.1    Cho, M.K.2    Lee, W.Y.3    Kang, K.W.4
  • 18
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • PMID:19487818
    • Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest 2009; 119:1420- 8; PMID:19487818; http://dx.doi.org/10.1172/ JCI39104
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 19
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • PMID:16493418
    • Thiery JP, Sleeman JP. Complex networks orchestrate epithelial- mesenchymal transitions. Nat Rev Mol Cell Biol 2006; 7:131-42; PMID:16493418; http://dx.doi. org/10.1038/nrm1835
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 20
    • 65349132693 scopus 로고    scopus 로고
    • EMT, the cytoskeleton, and cancer cell invasion
    • PMID:19169796
    • Yilmaz M, Christofori G. EMT, the cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev 2009; 28:15-33; PMID:19169796; http://dx.doi. org/10.1007/s10555-008-9169-0
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 15-33
    • Yilmaz, M.1    Christofori, G.2
  • 21
    • 79954538151 scopus 로고    scopus 로고
    • P53-dependent regulation of growth, epithelial-mesenchymal transition and stemness in normal pancreatic epithelial cells
    • PMID:21490434
    • Pinho AV, Rooman I, Real FX. p53-dependent regulation of growth, epithelial-mesenchymal transition and stemness in normal pancreatic epithelial cells. Cell Cycle 2011; 10:1312-21; PMID:21490434; http://dx.doi.org/10.4161/cc. 10.8.15363
    • (2011) Cell Cycle , vol.10 , pp. 1312-1321
    • Pinho, A.V.1    Rooman, I.2    Real, F.X.3
  • 22
    • 84055184850 scopus 로고    scopus 로고
    • MiR-34 and SNAIL form a doublenegative feedback loop to regulate epithelial-mesenchymal transitions
    • PMID:22134354
    • Siemens H, Jackstadt R, Hünten S, Kaller M, Menssen A, Götz U, et al. miR-34 and SNAIL form a doublenegative feedback loop to regulate epithelial-mesenchymal transitions. Cell Cycle 2011; 10:4256- 71; PMID:22134354; http://dx.doi.org/10.4161/cc.10.24.18552
    • (2011) Cell Cycle , vol.10 , pp. 4256-4271
    • Siemens, H.1    Jackstadt, R.2    Hünten, S.3    Kaller, M.4    Menssen, A.5    Götz, U.6
  • 23
    • 77649275464 scopus 로고    scopus 로고
    • MiR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
    • PMID: 20173740
    • Ma L, Young J, Prabhala H, Pan E, Mestdagh P, Muth D, et al. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol 2010; 12:247-56; PMID:20173740
    • (2010) Nat Cell Biol , vol.12 , pp. 247-256
    • Ma, L.1    Young, J.2    Prabhala, H.3    Pan, E.4    Mestdagh, P.5    Muth, D.6
  • 24
    • 84861216602 scopus 로고    scopus 로고
    • Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial-mesenchymal transition
    • PMID:22547830
    • Sakuma K, Aoki M, Kannagi R. Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial-mesenchymal transition. Proc Natl Acad Sci USA 2012; 109:7776-81; PMID:22547830; http://dx.doi.org/10.1073/pnas.1111135109
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 7776-7781
    • Sakuma, K.1    Aoki, M.2    Kannagi, R.3
  • 25
    • 84857798740 scopus 로고    scopus 로고
    • Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce epithelial- mesenchymaltransition
    • PMID:21813470
    • Zhu W, Cai MY, Tong ZT, Dong SS, Mai SJ, Liao YJ, et al. Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce epithelial-mesenchymaltransition. Gut 2012; 61:562-75; PMID:21813470; http://dx.doi.org/10.1136/gutjnl-2011-300207
    • (2012) Gut , vol.61 , pp. 562-575
    • Zhu, W.1    Cai, M.Y.2    Tong, Z.T.3    Dong, S.S.4    Mai, S.J.5    Liao, Y.J.6
  • 26
    • 84867296323 scopus 로고    scopus 로고
    • C-Myc expression and MEK1-induced Erk2 nuclear localization are required for TGF-βeta induced epithelial-mesenchymal transition and invasion in prostate cancer
    • PMID:22791812
    • Amatangelo MD, Goodyear S, Varma D, Stearns ME. c-Myc expression and MEK1-induced Erk2 nuclear localization are required for TGF-βeta induced epithelial-mesenchymal transition and invasion in prostate cancer. Carcinogenesis 2012; 33:1965-75; PMID:22791812; http://dx.doi.org/10.1093/ carcin/bgs227
    • (2012) Carcinogenesis , vol.33 , pp. 1965-1975
    • Amatangelo, M.D.1    Goodyear, S.2    Varma, D.3    Stearns, M.E.4
  • 27
    • 84863516199 scopus 로고    scopus 로고
    • Overexpression of TWIST2 correlates with poor prognosis in head and neck squamous cell carcinomas
    • PMID: 22201613
    • Gasparotto D, Polesel J, Marzotto A, Colladel R, Piccinin S, Modena P, et al. Overexpression of TWIST2 correlates with poor prognosis in head and neck squamous cell carcinomas. Oncotarget 2011; 2:1165-75; PMID:22201613
    • (2011) Oncotarget , vol.2 , pp. 1165-1175
    • Gasparotto, D.1    Polesel, J.2    Marzotto, A.3    Colladel, R.4    Piccinin, S.5    Modena, P.6
  • 28
    • 84862008052 scopus 로고    scopus 로고
    • Cord blood stem cells revert glioma stem cell EMT by down regulating transcriptional activation of Sox2 and Twist1
    • PMID: 22184289
    • Velpula KK, Dasari VR, Tsung AJ, Dinh DH, Rao JS. Cord blood stem cells revert glioma stem cell EMT by down regulating transcriptional activation of Sox2 and Twist1. Oncotarget 2011; 2:1028-42; PMID:22184289
    • (2011) Oncotarget , vol.2 , pp. 1028-1042
    • Velpula, K.K.1    Dasari, V.R.2    Tsung, A.J.3    Dinh, D.H.4    Rao, J.S.5
  • 29
    • 77957551870 scopus 로고    scopus 로고
    • A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
    • PMID:20621050
    • Li R, Liang J, Ni S, Zhou T, Qing X, Li H, et al. A mesenchymal-to- epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 2010; 7:51-63; PMID:20621050; http://dx.doi.org/10.1016/j. stem.2010.04.014
    • (2010) Cell Stem Cell , vol.7 , pp. 51-63
    • Li, R.1    Liang, J.2    Ni, S.3    Zhou, T.4    Qing, X.5    Li, H.6
  • 30
    • 67650386543 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cell lines from Tibetan miniature pig
    • PMID:19376775
    • Esteban MA, Xu J, Yang J, Peng M, Qin D, Li W, et al. Generation of induced pluripotent stem cell lines from Tibetan miniature pig. J Biol Chem 2009; 284:17634- 40; PMID:19376775; http://dx.doi.org/10.1074/jbc. M109.008938
    • (2009) J Biol Chem , vol.284 , pp. 17634-17640
    • Esteban, M.A.1    Xu, J.2    Yang, J.3    Peng, M.4    Qin, D.5    Li, W.6
  • 31
    • 80052423435 scopus 로고    scopus 로고
    • Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer
    • PMID:21862874
    • Jordan NV, Johnson GL, Abell AN. Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer. Cell Cycle 2011; 10:2865-73; PMID:21862874; http://dx.doi. org/10.4161/cc.10.17.17188
    • (2011) Cell Cycle , vol.10 , pp. 2865-2873
    • Jordan, N.V.1    Johnson, G.L.2    Abell, A.N.3
  • 32
    • 84869435129 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition (EMT) confers primary resistance to trastuzumab (Herceptin)
    • PMID:22992620
    • Oliveras-Ferraros C, Corominas-Faja B, Cufí S, Vazquez-Martin A, Martin-Castillo B, Iglesias JM, et al. Epithelial-to-mesenchymal transition (EMT) confers primary resistance to trastuzumab (Herceptin). Cell Cycle 2012; 11:4020-32; PMID:22992620; http://dx.doi.org/10.4161/cc.22225
    • (2012) Cell Cycle , vol.11 , pp. 4020-4032
    • Oliveras-Ferraros, C.1    Corominas-Faja, B.2    Cufí, S.3    Vazquez-Martin, A.4    Martin-Castillo, B.5    Iglesias, J.M.6
  • 33
    • 38949173196 scopus 로고    scopus 로고
    • Human mesenchymal stem cell transformation is associated with a mesenchymal-epithelial transition
    • PMID:18201695
    • Rubio D, Garcia S, De la Cueva T, Paz MF, Lloyd AC, Bernad A, et al. Human mesenchymal stem cell transformation is associated with a mesenchymal-epithelial transition. Exp Cell Res 2008; 314:691- 8; PMID:18201695; http://dx.doi.org/10.1016/j. yexcr.2007.11.017
    • (2008) Exp Cell Res , vol.314 , pp. 691-698
    • Rubio, D.1    Garcia, S.2    De La Cueva, T.3    Paz, M.F.4    Lloyd, A.C.5    Bernad, A.6
  • 34
    • 79955967003 scopus 로고    scopus 로고
    • Use of the 2A peptide for generation of multi-transgenic pigs through a single round of nuclear transfer
    • PMID:21603633
    • Deng W, Yang D, Zhao B, Ouyang Z, Song J, Fan N, et al. Use of the 2A peptide for generation of multi-transgenic pigs through a single round of nuclear transfer. PLoS ONE 2011; 6:e19986; PMID:21603633; http://dx.doi.org/10. 1371/journal.pone.0019986
    • (2011) PLoS ONE , vol.6
    • Deng, W.1    Yang, D.2    Zhao, B.3    Ouyang, Z.4    Song, J.5    Fan, N.6
  • 35
    • 0037039771 scopus 로고    scopus 로고
    • Production of alpha- 1,3-galactosyltransferase knockout pigs by nuclear transfer cloning
    • PMID:11778012
    • Lai L, Kolber-Simonds D, Park KW, Cheong HT, Greenstein JL, Im GS, et al. Production of alpha- 1,3-galactosyltransferase knockout pigs by nuclear transfer cloning. Science 2002; 295:1089-92; PMID:11778012; http://dx.doi.org/ 10.1126/science. 1068228
    • (2002) Science , vol.295 , pp. 1089-1092
    • Lai, L.1    Kolber-Simonds, D.2    Park, K.W.3    Cheong, H.T.4    Greenstein, J.L.5    Im, G.S.6
  • 36
    • 43049084102 scopus 로고    scopus 로고
    • Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors
    • PMID:18414447
    • Liao J, Wu Z, Wang Y, Cheng L, Cui C, Gao Y, et al. Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors. Cell Res 2008; 18:600-3; PMID:18414447; http://dx.doi. org/10.1038/cr.2008.51
    • (2008) Cell Res , vol.18 , pp. 600-603
    • Liao, J.1    Wu, Z.2    Wang, Y.3    Cheng, L.4    Cui, C.5    Gao, Y.6
  • 37
    • 84855191863 scopus 로고    scopus 로고
    • The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2
    • PMID:21672940
    • Zheng F, Liao YJ, Cai MY, Liu YH, Liu TH, Chen SP, et al. The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. Gut 2012; 61:278- 89; PMID:21672940; http://dx.doi.org/10.1136/gut.2011.239145
    • (2012) Gut , vol.61 , pp. 278-289
    • Zheng, F.1    Liao, Y.J.2    Cai, M.Y.3    Liu, Y.H.4    Liu, T.H.5    Chen, S.P.6
  • 38
    • 68249126627 scopus 로고    scopus 로고
    • MicroRNA MiR-17 retards tissue growth and represses fibronectin expression
    • PMID:19633662
    • Shan SW, Lee DY, Deng Z, Shatseva T, Jeyapalan Z, Du WW, et al. MicroRNA MiR-17 retards tissue growth and represses fibronectin expression. Nat Cell Biol 2009; 11:1031-8; PMID:19633662; http://dx.doi.org/10.1038/ncb1917
    • (2009) Nat Cell Biol , vol.11 , pp. 1031-1038
    • Shan, S.W.1    Lee, D.Y.2    Deng, Z.3    Shatseva, T.4    Jeyapalan, Z.5    Du, W.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.