Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-β-dependent mechanisms

Liver International

Volumn 30, Issue 5, 2010, Pages 669-682

  Copple, Bryan L ^a  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

Epithelial to mesenchymal transition; Fibroblast specific protein 1; Hepatocyte; Hypoxia inducible factors; Snail; Transforming growth factor

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ALBUMIN; ALPHA SMOOTH MUSCLE ACTIN; CALVASCULIN; CYTOKERATIN 19; F ACTIN; GLIAL FIBRILLARY ACIDIC PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; MESSENGER RNA; OXYGEN; PROTEIN ZO1; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; CELL HYPOXIA; CELL ISOLATION; CELL VIABILITY; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LIVER CELL; LIVER CELL CULTURE; LIVER FIBROSIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STELLATE CELL; WESTERN BLOTTING;

ACTINS; ANIMALS; CADHERINS; CALCIUM-BINDING PROTEINS; CELL HYPOXIA; EPITHELIAL CELLS; HEPATOCYTES; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KERATIN-19; MEMBRANE PROTEINS; MESODERM; MICE; MICE, INBRED C57BL; PHOSPHOPROTEINS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77954372059     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2010.02205.x     Document Type: Article

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