-
1
-
-
0026516994
-
Mechanism of action of taxol
-
Horwitz SB: Mechanism of action of taxol. Trends Pharmacol Sci 13: 134-136, 1992.
-
(1992)
Trends Pharmacol Sci
, vol.13
, pp. 134-136
-
-
Horwitz, S.B.1
-
3
-
-
0034064991
-
Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-x(L) protein levels
-
Tudor G, Aguilera A, Halverson DO, Laing ND and Sausville EA: Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-xL protein levels. Cell Death Differ 7: 574-586, 2000. (Pubitemid 30303613)
-
(2000)
Cell Death and Differentiation
, vol.7
, Issue.6
, pp. 574-586
-
-
Tudor, G.1
Aguilera, A.2
Halverson, D.O.3
Laing, N.D.4
Sausville, E.A.5
-
4
-
-
31544445749
-
2-terminal kinase and Akt
-
DOI 10.1158/0008-5472.CAN-05-1997
-
Sunters A, Madureira PA, Pomeranz KM, Aubert M, Brosens JJ, Cook SJ, Burgering BM, Coombes RC and Lam EW: Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt. Cancer Res 66: 212-220, 2006. (Pubitemid 43166027)
-
(2006)
Cancer Research
, vol.66
, Issue.1
, pp. 212-220
-
-
Sunters, A.1
Madureira, P.A.2
Pomeranz, K.M.3
Aubert, M.4
Brosens, J.J.5
Cook, S.J.6
Burgering, B.M.T.7
Coombes, R.C.8
Lam, E.W.-F.9
-
5
-
-
70350728798
-
Alpha-tocopheryl succinate potentiates the paclitaxel-induced apoptosis through enforced caspase 8 activation in human H460 lung cancer cells
-
Lim SJ, Choi MK, Kim MJ and Kim JK: Alpha-tocopheryl succinate potentiates the paclitaxel-induced apoptosis through enforced caspase 8 activation in human H460 lung cancer cells. Exp Mol Med 41: 737-745, 2009.
-
(2009)
Exp Mol Med
, vol.41
, pp. 737-745
-
-
Lim, S.J.1
Choi, M.K.2
Kim, M.J.3
Kim, J.K.4
-
6
-
-
41549126681
-
Distinct signaling pathways of microtubule inhibitors-vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively
-
Kolomeichuk SN, Terrano DT, Lyle CS, Sabapathy K and Chambers TC: Distinct signaling pathways of microtubule inhibitors-vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively. FEBS J 275: 1889-1899, 2008.
-
(2008)
FEBS J
, vol.275
, pp. 1889-1899
-
-
Kolomeichuk, S.N.1
Terrano, D.T.2
Lyle, C.S.3
Sabapathy, K.4
Chambers, T.C.5
-
7
-
-
0028972011
-
Taxol induction of p21WAF1 and p53 requires c-raf-1
-
Blagosklonny MV, Schulte TW, Nguyen P, Mimnaugh EG, Trepel J and Neckers L: Taxol induction of p21WAF1 and p53 requires c-raf-1. Cancer Res 55: 4623-4626, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 4623-4626
-
-
Blagosklonny, M.V.1
Schulte, T.W.2
Nguyen, P.3
Mimnaugh, E.G.4
Trepel, J.5
Neckers, L.6
-
8
-
-
0030886975
-
P53-independent apoptosis induced by paclitaxel through an indirect mechanism
-
DOI 10.1073/pnas.94.18.9679
-
Lanni JS, Lowe SW, Licitra EJ, Liu JO and Jacks T: p53-independent apoptosis induced by paclitaxel through an indirect mechanism. Proc Natl Acad Sci USA 94: 9679-9683, 1997. (Pubitemid 27408122)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.18
, pp. 9679-9683
-
-
Lanni, J.S.1
Lowe, S.W.2
Licitra, E.J.3
Liu, J.O.4
Jacks, T.5
-
9
-
-
0029328641
-
Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway
-
Woods CM, Zhu J, McQueney PA, Bollag D and Lazarides E: Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway. Mol Med 1: 506-526, 1995.
-
(1995)
Mol Med
, vol.1
, pp. 506-526
-
-
Woods, C.M.1
Zhu, J.2
McQueney, P.A.3
Bollag, D.4
Lazarides, E.5
-
10
-
-
0031020572
-
Paclitaxel-induced apoptosis in MCF-7 breast-cancer cells
-
Saunders DE, Lawrence WD, Christensen C, Wappler NL, Ruan H and Deppe G: Paclitaxel-induced apoptosis in MCF-7 breast-cancer cells. Int J Cancer 70: 214-220, 1997.
-
(1997)
Int J Cancer
, vol.70
, pp. 214-220
-
-
Saunders, D.E.1
Lawrence, W.D.2
Christensen, C.3
Wappler, N.L.4
Ruan, H.5
Deppe, G.6
-
11
-
-
38849110894
-
Basic-helix-loop-helix (bHLH) transcription factor DEC2 negatively regulates vascular endothelial growth factor expression
-
DOI 10.1111/j.1365-2443.2007.01153.x
-
Sato F, Bhawal UK, Kawamoto T, Fujimoto K, Imaizumi T, Imanaka T, Kondo J, Koyanagi S, Noshiro M, Yoshida H, Kusumi T, Kato Y and Kijima H: Basic-helix-loop-helix (bHLH) transcription factor DEC2 negatively regulates vascular endothelial growth factor expression. Genes Cells 13: 131-144, 2008. (Pubitemid 351188984)
-
(2008)
Genes to Cells
, vol.13
, Issue.2
, pp. 131-144
-
-
Sato, F.1
Bhawal, U.K.2
Kawamoto, T.3
Fujimoto, K.4
Imaizumi, T.5
Imanaka, T.6
Kondo, J.7
Koyanagi, S.8
Noshiro, M.9
Yoshida, H.10
Kusumi, T.11
Kato, Y.12
Kijima, H.13
-
12
-
-
77954665205
-
Anti-apoptotic effect of the basic helix-loop-helix (bHLH) transcription factor DEC2 in human breast cancer cells
-
Liu Y, Sato F, Kawamoto T, Fujimoto K, Morohashi S, Akasaka H, Kondo J, Wu Y, Noshiro M, Kato Y and Kijima H: Anti-apoptotic effect of the basic helix-loop-helix (bHLH) transcription factor DEC2 in human breast cancer cells. Genes Cells 15: 315-325, 2010.
-
(2010)
Genes Cells
, vol.15
, pp. 315-325
-
-
Liu, Y.1
Sato, F.2
Kawamoto, T.3
Fujimoto, K.4
Morohashi, S.5
Akasaka, H.6
Kondo, J.7
Wu, Y.8
Noshiro, M.9
Kato, Y.10
Kijima, H.11
-
13
-
-
33745713607
-
57Arg in the bHLH transcription factor DEC2 is essential for the suppression of CLOCK/BMAL2-mediated transactivation
-
Kondo J, Sato F, Fujimoto K, Kusumi T, Imanaka T, Kawamoto T, Uk B, Noshiro M, Kato Y, Sato T and Kijima H: 57Arg in the bHLH transcription factor DEC2 is essential for the suppression of CLOCK/BMAL2-mediated transactivation. Int J Mol Med 17: 1053-1056, 2006.
-
(2006)
Int J Mol Med
, vol.17
, pp. 1053-1056
-
-
Kondo, J.1
Sato, F.2
Fujimoto, K.3
Kusumi, T.4
Imanaka, T.5
Kawamoto, T.6
Uk, B.7
Noshiro, M.8
Kato, Y.9
Sato, T.10
Kijima, H.11
-
14
-
-
4644312033
-
The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers
-
DOI 10.1038/sj.bjc.6602059
-
Chakrabarti J, Turley H, Campo L, Han C, Harris AL, Gatter KC and Fox SB: The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers. Br J Cancer 31: 954-958, 2004. (Pubitemid 39273790)
-
(2004)
British Journal of Cancer
, vol.91
, Issue.5
, pp. 954-958
-
-
Chakrabarti, J.1
Turley, H.2
Campo, L.3
Han, C.4
Harris, A.L.5
Gatter, K.C.6
Fox, S.B.7
-
15
-
-
0037108919
-
Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: Its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation
-
DOI 10.1042/BJ20020514
-
Li Y, Zhang H, Xie M, Hu M, Ge S, Yang D, Wan Y and Yan B: Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation. Biochem J 367: 413-422, 2002. (Pubitemid 35216815)
-
(2002)
Biochemical Journal
, vol.367
, Issue.2
, pp. 413-422
-
-
Li, Y.1
Zhang, H.2
Xie, M.3
Hu, M.4
Ge, S.5
Yang, D.6
Wan, Y.7
Yan, B.8
-
16
-
-
33744925726
-
The expression of anti-apoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter
-
Li Y, Xie M, Yang J, Yang D, Deng R, Wan Y and Yan B: The expression of anti-apoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter. Oncogene 23: 3298-3306, 2006.
-
(2006)
Oncogene
, vol.23
, pp. 3298-3306
-
-
Li, Y.1
Xie, M.2
Yang, J.3
Yang, D.4
Deng, R.5
Wan, Y.6
Yan, B.7
-
17
-
-
9644269066
-
Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation: Interaction with BMAL1
-
DOI 10.1111/j.1432-1033.2004.04379.x
-
Sato F, Kawamoto T, Fujimoto K, Noshiro M, Honda KK, Honma S, Honma K and Kato Y: Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1. Eur J Biochem 22: 4409-4419, 2004. (Pubitemid 39576558)
-
(2004)
European Journal of Biochemistry
, vol.271
, Issue.22
, pp. 4409-4419
-
-
Sato, F.1
Kawamoto, T.2
Fujimoto, K.3
Noshiro, M.4
Honda, K.K.5
Honma, S.6
Honma, K.-I.7
Kato, Y.8
-
18
-
-
44949089601
-
DEC1 modulates the circadian phase of clock gene expression
-
DOI 10.1128/MCB.02168-07
-
Nakashima A, Kawamoto T, Honda KK, Ueshima T, Noshiro M, Iwata T, Fujimoto K, Kubo H, Honma S, Yorioka N, Kohno N and Kato Y: DEC1 modulates the circadian phase of clock gene expression. Mol Cell Biol 28: 4080-4092, 2008. (Pubitemid 351812992)
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.12
, pp. 4080-4092
-
-
Nakashima, A.1
Kawamoto, T.2
Honda, K.K.3
Ueshima, T.4
Noshiro, M.5
Iwata, T.6
Fujimoto, K.7
Kubo, H.8
Honma, S.9
Yorioka, N.10
Kohno, N.11
Kato, Y.12
-
19
-
-
70449707113
-
Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment
-
Yang XO, Angkasekwinai P, Zhu J, Peng J, Liu Z, Nurieva R, Liu X, Chung Y, Chang SH, Sun B and Dong C: Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment. Nat Immunol 12: 1260-1266, 2009.
-
(2009)
Nat Immunol
, vol.12
, pp. 1260-1266
-
-
Yang, X.O.1
Angkasekwinai, P.2
Zhu, J.3
Peng, J.4
Liu, Z.5
Nurieva, R.6
Liu, X.7
Chung, Y.8
Chang, S.H.9
Sun, B.10
Dong, C.11
-
20
-
-
34047158745
-
Stra13 is induced by genotoxic stress and regulates ionizing-radiation- induced apoptosis
-
DOI 10.1038/sj.embor.7400912, PII 7400912
-
Thin TH, Li L, Chung TK, Sun H and Taneja R: Stra13 is induced by genotoxic stress and regulates ionizing-radiation-induced apoptosis. EMBO Rep 4: 401-407, 2007. (Pubitemid 46511042)
-
(2007)
EMBO Reports
, vol.8
, Issue.4
, pp. 401-407
-
-
Thin, T.H.1
Li, L.2
Chung, T.-K.3
Sun, H.4
Taneja, R.5
-
21
-
-
35448997708
-
Transforming growth factor-beta promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC1
-
DOI 10.1158/0008-5472.CAN-07-1522
-
Ehata S, Hanyu A, Hayashi M, Aburatani H, Kato Y, Fujime M, Saitoh M, Miyazawa K, Imamura T and Miyazono K: Transforming growth factor-beta promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DECl. Cancer Res 67: 9694-9703, 2007. (Pubitemid 47621216)
-
(2007)
Cancer Research
, vol.67
, Issue.20
, pp. 9694-9703
-
-
Ehata, S.1
Hanyu, A.2
Hayashi, M.3
Aburatani, H.4
Kato, Y.5
Fujime, M.6
Saitoh, M.7
Miyazawa, K.8
Imamura, T.9
Miyazono, K.10
-
22
-
-
10744225254
-
A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation
-
DOI 10.1016/j.bbrc.2003.11.099
-
Kawamoto T, Noshiro M, Sato F, Maemura K, Takeda N, Nagai R, Iwata T, Fujimoto K, Furukawa M, Miyazaki K, Honma S, Honma K and Kato Y: A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation. Biochem Biophys Res Commun 313: 117-124, 2004. (Pubitemid 37524033)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.313
, Issue.1
, pp. 117-124
-
-
Kawamoto, T.1
Noshiro, M.2
Sato, F.3
Maemura, K.4
Takeda, N.5
Nagai, R.6
Iwata, T.7
Fujimoto, K.8
Furukawa, M.9
Miyazaki, K.10
Honma, S.11
Honma, K.-I.12
Kato, Y.13
-
23
-
-
0037033095
-
Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes
-
DOI 10.1074/jbc.M204938200
-
Miyazaki K, Kawamoto T, Tanimoto K, Nishiyama M, Honda H and Kato Y: Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes. J Biol Chem 277: 47014-47021, 2002. (Pubitemid 36159208)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.49
, pp. 47014-47021
-
-
Miyazaki, K.1
Kawamoto, T.2
Tanimoto, K.3
Nishiyama, M.4
Honda, H.5
Kato, Y.6
-
24
-
-
0042733340
-
Insulin induces the expression of the SHARP-2/Stra13/DEC1 gene via a phosphoinositide 3-kinase pathway
-
DOI 10.1074/jbc.M301597200
-
Yamada K, Kawata H, Shou Z, Mizutani T, Noguchi T and Miyamoto K: Insulin induces the expression of the SHARP-2/Stra13/DEC1 gene via a phosphoinositide 3-kinase pathway. J Biol Chem 278: 30719-30724, 2003. (Pubitemid 36994578)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.33
, pp. 30719-30724
-
-
Yamada, K.1
Kawata, H.2
Shou, Z.3
Mizutani, T.4
Noguchi, T.5
Miyamoto, K.6
-
25
-
-
57149098568
-
Activation of TGF-beta/activin signalling resets the circadian clock through rapid induction of Dec1 transcripts
-
Kon N, Hirota T, Kawamoto T, Kato Y, Tsubota T and Fukada Y: Activation of TGF-beta/activin signalling resets the circadian clock through rapid induction of Dec1 transcripts. Nat Cell Biol 10: 1463-1469, 2008.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1463-1469
-
-
Kon, N.1
Hirota, T.2
Kawamoto, T.3
Kato, Y.4
Tsubota, T.5
Fukada, Y.6
-
26
-
-
0038482182
-
MSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of e box activity and Stra13 expression
-
DOI 10.1074/jbc.M210427200
-
Azmi S, Sun H, Ozog A and Taneja R: mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression. J Biol Chem 278: 20098-20109, 2003. (Pubitemid 36799204)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.22
, pp. 20098-20109
-
-
Azmi, S.1
Sun, H.2
Ozog, A.3
Taneja, R.4
-
27
-
-
41449091585
-
DEC1, a basic helix-loop-helix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence
-
Qian Y, Zhang J, Yan B and Chen X: DEC1, a basic helix-loop-helix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence. J Biol Chem 283: 2896-2905, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 2896-2905
-
-
Qian, Y.1
Zhang, J.2
Yan, B.3
Chen, X.4
-
28
-
-
0000591744
-
Bcl-2 protects macrophages from nitric oxide-induced apoptosis
-
Messmer UK, Reed UK and Brüne B: Bcl-2 protects macrophages from nitric oxide-induced apoptosis. J Biol Chem 271: 20192-20197, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 20192-20197
-
-
Messmer, U.K.1
Reed, U.K.2
Brüne, B.3
-
29
-
-
0034280579
-
Signal transduction mediated by Bid, a pro-death Bcl-2 family protein, connects the death receptor and mitochondria apoptosis pathways
-
Yin XM: Signal transduction mediated by Bid, a pro-death Bcl-2 family protein, connects the death receptor and mitochondria apoptosis pathways. Cell Res 10: 161-167, 2000.
-
(2000)
Cell Res
, vol.10
, pp. 161-167
-
-
Yin, X.M.1
|