Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 297, Issue 6, 2009, Pages

  Zhou, Guofei ^a   Dada, Laura A ^a   Wu, Minghua ^a   Kelly, Aileen ^a   Trejo, Humberto ^a   Zhou, Qiyuan ^b   Varga, John ^a   Sznajder, Jacob I ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Alveolar epithelial cells; Pulmonary fibrosis; Transforming growth factor 1

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ALPHA SMOOTH MUSCLE ACTIN; COBALT CHLORIDE; DIMETHYLOXALOYLGLYCINE; GLYCINE DERIVATIVE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYPOXIA; LUNG ALVEOLUS EPITHELIUM; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANOXIA; CELL LINE, TRANSFORMED; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; MESODERM; MICE; MITOCHONDRIA; PULMONARY ALVEOLI; RATS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA1;

EID: 71949128382     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00007.2009     Document Type: Article

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