Targeting the mitochondrial apoptotic pathway: A preferred approach in hematologic malignancies?

Cell Death and Disease

Volumn 5, Issue 3, 2014, Pages

  Brinkmann, K ^a,b   Kashkar, H ^a,b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Apoptosis; Bcl 2 targeting; BH3 mimetics

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; ABT 199; BH3 PROTEIN; GOSSYPOL; NATURAL PRODUCT; NAVITOCLAX; OBATOCLAX; OBLIMERSEN; PROTEIN BCL 2; UNCLASSIFIED DRUG;

APOPTOSIS; HEMATOLOGIC MALIGNANCY; HEMATOPOIESIS; HEMATOPOIETIC CELL; HEMATOPOIETIC SYSTEM; HOMEOSTASIS; HUMAN; MITOCHONDRION; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN TARGETING; REVIEW;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; DRUG DESIGN; HEMATOLOGIC NEOPLASMS; HUMANS; MITOCHONDRIA; MOLECULAR TARGETED THERAPY; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 84897387048     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.61     Document Type: Review

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