Genetically defining the mechanism of Puma-and Bim-induced apoptosis

Cell Death and Differentiation

Volumn 19, Issue 4, 2012, Pages 642-649

  Garrison, S P ^a   Phillips, D C ^a,b   Jeffers, J R ^a   Chipuk, J E ^a,c   Parsons, M J ^a   Rehg, J E ^a   Opferman, J T ^a   Green, D R ^a   Zambetti, G P ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b ABBOTT LABORATORIES   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

ABT 737; apoptosis; Bim; myelosuppression; Puma

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; BIM PROTEIN; CARBOPLATIN; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; PROTEIN P53; PUMA PROTEIN;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BONE MARROW DEPRESSION; BONE MARROW SUPPRESSION; BONE MARROW TOXICITY; CANCER SURVIVAL; CANCER SUSCEPTIBILITY; CELL DEATH; DNA DAMAGE; ENZYME ACTIVATION; GASTROINTESTINAL TOXICITY; GENE DELETION; IONIZING RADIATION; MAST CELL; MEMBRANE PERMEABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BIPHENYL COMPOUNDS; CELL SURVIVAL; CYTOCHROMES C; DNA DAMAGE; GENE DELETION; HEMOGLOBINURIA, PAROXYSMAL; MAST CELLS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MITOCHONDRIAL MEMBRANES; NITROPHENOLS; PERMEABILITY; PIPERAZINES; PROTO-ONCOGENE PROTEINS; SULFONAMIDES; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84858155326     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.136     Document Type: Article

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