메뉴 건너뛰기




Volumn 14, Issue 3, 2013, Pages 290-297

Mcl-1 is essential for the survival of plasma cells

Author keywords

[No Author keywords available]

Indexed keywords

B CELL MATURATION ANTIGEN; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; PROTEIN BCL 2; PROTEIN MCL 1;

EID: 85027921645     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2527     Document Type: Article
Times cited : (252)

References (50)
  • 1
    • 18444395232 scopus 로고    scopus 로고
    • Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program
    • Shaffer, A.L. et al. Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity 17, 51-62 (2002).
    • (2002) Immunity , vol.17 , pp. 51-62
    • Shaffer, A.L.1
  • 2
    • 0142219442 scopus 로고    scopus 로고
    • Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells
    • Shapiro-Shelef, M. et al. Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. Immunity 19, 607-620 (2003).
    • (2003) Immunity , vol.19 , pp. 607-620
    • Shapiro-Shelef, M.1
  • 3
    • 34248543774 scopus 로고    scopus 로고
    • Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1
    • Kallies, A. et al. Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1. Immunity 26, 555-566 (2007).
    • (2007) Immunity , vol.26 , pp. 555-566
    • Kallies, A.1
  • 4
    • 7244231012 scopus 로고    scopus 로고
    • Plasma cell ontogeny defined by quantitative changes in Blimp-1 expression
    • Kallies, A. et al. Plasma cell ontogeny defined by quantitative changes in Blimp-1 expression. J. Exp. Med. 200, 967-977 (2004).
    • (2004) J. Exp. Med. , vol.200 , pp. 967-977
    • Kallies, A.1
  • 5
    • 0033806822 scopus 로고    scopus 로고
    • Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival
    • Sze, D.M., Toellner, K.M., Garcia de Vinuesa, C., Taylor, D.R. & MacLennan, I.C. Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival. J. Exp. Med. 192, 813-821 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 813-821
    • Sze, D.M.1    Toellner, K.M.2    Garcia De Vinuesa, C.3    Taylor, D.R.4    MacLennan, I.C.5
  • 6
    • 33749021665 scopus 로고    scopus 로고
    • B-cell memory: Are subsets necessary? Nat
    • Tarlinton, D. B-cell memory: are subsets necessary? Nat. Rev. Immunol. 6, 785-790 (2006).
    • (2006) Rev. Immunol. , vol.6 , pp. 785-790
    • Tarlinton, D.1
  • 7
    • 0030006070 scopus 로고    scopus 로고
    • Clonal selection and learning in the antibody system
    • Rajewsky, K. Clonal selection and learning in the antibody system. Nature 381, 751-758 (1996).
    • (1996) Nature , vol.381 , pp. 751-758
    • Rajewsky, K.1
  • 8
    • 33751530065 scopus 로고    scopus 로고
    • Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism
    • Kabashima, K. et al. Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism. J. Exp. Med. 203, 2683-2690 (2006).
    • (2006) J. Exp. Med. , vol.203 , pp. 2683-2690
    • Kabashima, K.1
  • 11
    • 0030026284 scopus 로고    scopus 로고
    • The phenotype and fate of the antibody-forming cells of the splenic foci
    • Smith, K.G., Hewitson, T.D., Nossal, G.J. & Tarlinton, D.M. The phenotype and fate of the antibody-forming cells of the splenic foci. Eur. J. Immunol. 26, 444-448 (1996).
    • (1996) Eur. J. Immunol. , vol.26 , pp. 444-448
    • Smith, K.G.1    Hewitson, T.D.2    Nossal, G.J.3    Tarlinton, D.M.4
  • 12
    • 0347285357 scopus 로고    scopus 로고
    • BCMA is essential for the survival of long-lived bone marrow plasma cells
    • O'Connor, B.P. et al. BCMA is essential for the survival of long-lived bone marrow plasma cells. J. Exp. Med. 199, 91-98 (2004).
    • (2004) J. Exp. Med. , vol.199 , pp. 91-98
    • O'connor, B.P.1
  • 13
    • 44849097480 scopus 로고    scopus 로고
    • Cutting edge: The dependence of plasma cells and independence of memory B cells on BAFF and APRIL
    • Benson, M.J. et al. Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. J. Immunol. 180, 3655-3659 (2008).
    • (2008) J. Immunol. , vol.180 , pp. 3655-3659
    • Benson, M.J.1
  • 14
    • 0042591464 scopus 로고    scopus 로고
    • Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals
    • Cassese, G. et al. Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals. J. Immunol. 171, 1684-1690 (2003).
    • (2003) J. Immunol. , vol.171 , pp. 1684-1690
    • Cassese, G.1
  • 15
    • 78650647718 scopus 로고    scopus 로고
    • Basophils support the survival of plasma cells in mice
    • Rodriguez Gomez, M. et al. Basophils support the survival of plasma cells in mice. J. Immunol. 185, 7180-7185 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 7180-7185
    • Rodriguez Gomez, M.1
  • 16
    • 79960372865 scopus 로고    scopus 로고
    • Sustained antibody responses depend on CD28 function in bone marrow-resident plasma cells
    • Rozanski, C.H. et al. Sustained antibody responses depend on CD28 function in bone marrow-resident plasma cells. J. Exp. Med. 208, 1435-1446 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 1435-1446
    • Rozanski, C.H.1
  • 17
    • 2942523585 scopus 로고    scopus 로고
    • Cellular niches controlling B lymphocyte behavior within bone marrow during development
    • Tokoyoda, K., Egawa, T., Sugiyama, T., Choi, B.I. & Nagasawa, T. Cellular niches controlling B lymphocyte behavior within bone marrow during development. Immunity 20, 707-718 (2004).
    • (2004) Immunity , vol.20 , pp. 707-718
    • Tokoyoda, K.1    Egawa, T.2    Sugiyama, T.3    Choi, B.I.4    Nagasawa, T.5
  • 19
    • 0038336667 scopus 로고    scopus 로고
    • Neoplastic development in plasma cells
    • Potter, M. Neoplastic development in plasma cells. Immunol. Rev. 194, 177-195 (2003).
    • (2003) Immunol. Rev. , vol.194 , pp. 177-195
    • Potter, M.1
  • 20
    • 41949138741 scopus 로고    scopus 로고
    • APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells
    • Belnoue, E. et al. APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells. Blood 111, 2755-2764 (2008).
    • (2008) Blood , vol.111 , pp. 2755-2764
    • Belnoue, E.1
  • 21
    • 11144355586 scopus 로고    scopus 로고
    • BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone
    • Moreaux, J. et al. BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone. Blood 103, 3148-3157 (2004).
    • (2004) Blood , vol.103 , pp. 3148-3157
    • Moreaux, J.1
  • 22
    • 77954649027 scopus 로고    scopus 로고
    • BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs
    • Carrington, E.M. et al. BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs. Proc. Natl. Acad. Sci. USA 107, 10967-10971 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 10967-10971
    • Carrington, E.M.1
  • 23
    • 84862489317 scopus 로고    scopus 로고
    • Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells
    • Mérino, D. et al. Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells. Blood 119, 5807-5816 (2012).
    • (2012) Blood , vol.119 , pp. 5807-5816
    • Mérino, D.1
  • 24
    • 78449282121 scopus 로고    scopus 로고
    • Mcl-1 is essential for germinal center formation and B cell memory
    • Vikstrom, I. et al. Mcl-1 is essential for germinal center formation and B cell memory. Science 330, 1095-1099 (2010).
    • (2010) Science , vol.330 , pp. 1095-1099
    • Vikstrom, I.1
  • 25
    • 2442617195 scopus 로고    scopus 로고
    • The Bcl-2 family member Bfl-1/A1 is strongly repressed in normal and malignant plasma cells but is a potent anti-apoptotic factor for myeloma cells
    • Tarte, K. et al. The Bcl-2 family member Bfl-1/A1 is strongly repressed in normal and malignant plasma cells but is a potent anti-apoptotic factor for myeloma cells. Br. J. Haematol. 125, 373-382 (2004).
    • (2004) Br. J. Haematol. , vol.125 , pp. 373-382
    • Tarte, K.1
  • 26
    • 81355127378 scopus 로고    scopus 로고
    • Staying alive: Regulation of plasma cell survival
    • Tangye, S.G. Staying alive: regulation of plasma cell survival. Trends Immunol. 32, 595-602 (2011).
    • (2011) Trends Immunol. , vol.32 , pp. 595-602
    • Tangye, S.G.1
  • 27
    • 79958047299 scopus 로고    scopus 로고
    • B cell maturation antigen deficiency exacerbates lymphoproliferation and autoimmunity in murine lupus
    • Jiang, C., Loo, W.M., Greenley, E.J., Tung, K.S. & Erickson, L.D. B cell maturation antigen deficiency exacerbates lymphoproliferation and autoimmunity in murine lupus. J. Immunol. 186, 6136-6147 (2011).
    • (2011) J. Immunol. , vol.186 , pp. 6136-6147
    • Jiang, C.1    Loo, W.M.2    Greenley, E.J.3    Tung, K.S.4    Erickson, L.D.5
  • 28
    • 60549092755 scopus 로고    scopus 로고
    • Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells
    • Good, K.L., Avery, D.T. & Tangye, S.G. Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells. J. Immunol. 182, 890-901 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 890-901
    • Good, K.L.1    Avery, D.T.2    Tangye, S.G.3
  • 29
    • 84856270102 scopus 로고    scopus 로고
    • Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia
    • Glaser, S.P. et al. Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia. Genes Dev. 26, 120-125 (2012).
    • (2012) Genes Dev. , vol.26 , pp. 120-125
    • Glaser, S.P.1
  • 30
    • 80052643363 scopus 로고    scopus 로고
    • Vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo
    • Nojima, T. et al. In vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo. Nat. Commun. 2, 465 (2011).
    • (2011) Nat. Commun. , vol.2 , pp. 465
    • Nojima, T.1
  • 31
    • 0023856770 scopus 로고
    • The half-lives of serum immunoglobulins in adult mice
    • Vieira, P. & Rajewsky, K. The half-lives of serum immunoglobulins in adult mice. Eur. J. Immunol. 18, 313-316 (1988).
    • (1988) Eur. J. Immunol. , vol.18 , pp. 313-316
    • Vieira, P.1    Rajewsky, K.2
  • 32
    • 35848969753 scopus 로고    scopus 로고
    • Duration of humoral immunity to common viral and vaccine antigens
    • Amanna, I.J., Carlson, N.E. & Slifka, M.K. Duration of humoral immunity to common viral and vaccine antigens. N. Engl. J. Med. 357, 1903-1915 (2007).
    • (2007) N. Engl. J. Med. , vol.357 , pp. 1903-1915
    • Amanna, I.J.1    Carlson, N.E.2    Slifka, M.K.3
  • 33
    • 0141796316 scopus 로고    scopus 로고
    • Duration of antiviral immunity after smallpox vaccination
    • Hammarlund, E. et al. Duration of antiviral immunity after smallpox vaccination. Nat. Med. 9, 1131-1137 (2003).
    • (2003) Nat. Med. , vol.9 , pp. 1131-1137
    • Hammarlund, E.1
  • 34
    • 0242495755 scopus 로고    scopus 로고
    • Cutting edge: Long-term B cell memory in humans after smallpox vaccination
    • Crotty, S. et al. Cutting edge: long-term B cell memory in humans after smallpox vaccination. J. Immunol. 171, 4969-4973 (2003).
    • (2003) J. Immunol. , vol.171 , pp. 4969-4973
    • Crotty, S.1
  • 35
    • 33749018225 scopus 로고    scopus 로고
    • Competence and competition: The challenge of becoming a long-lived plasma cell
    • Radbruch, A. et al. Competence and competition: the challenge of becoming a long-lived plasma cell. Nat. Rev. Immunol. 6, 741-750 (2006).
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 741-750
    • Radbruch, A.1
  • 36
    • 78751627318 scopus 로고    scopus 로고
    • Eosinophils are required for the maintenance of plasma cells in the bone marrow
    • Chu, V.T. et al. Eosinophils are required for the maintenance of plasma cells in the bone marrow. Nat. Immunol. 12, 151-159 (2011).
    • (2011) Nat. Immunol. , vol.12 , pp. 151-159
    • Chu, V.T.1
  • 37
    • 61449162967 scopus 로고    scopus 로고
    • Dendritic cells and monocyte/macrophages that create the IL-6/APRIL-rich lymph node microenvironments where plasmablasts mature
    • Mohr, E. et al. Dendritic cells and monocyte/macrophages that create the IL-6/APRIL-rich lymph node microenvironments where plasmablasts mature. J. Immunol. 182, 2113-2123 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 2113-2123
    • Mohr, E.1
  • 38
    • 48749100460 scopus 로고    scopus 로고
    • APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa
    • Huard, B. et al. APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa. J. Clin. Invest. 118, 2887-2895 (2008).
    • (2008) J. Clin. Invest. , vol.118 , pp. 2887-2895
    • Huard, B.1
  • 39
    • 33747133955 scopus 로고    scopus 로고
    • Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation
    • Sciammas, R. et al. Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity 25, 225-236 (2006).
    • (2006) Immunity , vol.25 , pp. 225-236
    • Sciammas, R.1
  • 40
    • 47049120726 scopus 로고    scopus 로고
    • IRF4 addiction in multiple myeloma
    • Shaffer, A.L. et al. IRF4 addiction in multiple myeloma. Nature 454, 226-231 (2008).
    • (2008) Nature , vol.454 , pp. 226-231
    • Shaffer, A.L.1
  • 42
    • 0942298590 scopus 로고    scopus 로고
    • Expression of BCMA, TACI, and BAFF-R in multiple myeloma: A mechanism for growth and survival
    • Novak, A.J. et al. Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival. Blood 103, 689-694 (2004).
    • (2004) Blood , vol.103 , pp. 689-694
    • Novak, A.J.1
  • 44
    • 21744457447 scopus 로고    scopus 로고
    • Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival
    • Wuillème-Toumi, S. et al. Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival. Leukemia 19, 1248-1252 (2005).
    • (2005) Leukemia , vol.19 , pp. 1248-1252
    • Wuillème-Toumi, S.1
  • 45
    • 79959856423 scopus 로고    scopus 로고
    • Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate: Results of a phase II, randomized, placebo-controlled trial
    • van Vollenhoven, R.F., Kinnman, N., Vincent, E., Wax, S. & Bathon, J. Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a phase II, randomized, placebo-controlled trial. Arthritis Rheum. 63, 1782-1792 (2011).
    • (2011) Arthritis Rheum. , vol.63 , pp. 1782-1792
    • Van Vollenhoven, R.F.1    Kinnman, N.2    Vincent, E.3    Wax, S.4    Bathon, J.5
  • 46
    • 79959832697 scopus 로고    scopus 로고
    • Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: Results of a phase II, randomized, placebo-controlled, dose-finding trial
    • Genovese, M.C., Kinnman, N., de La Bourdonnaye, G., Pena Rossi, C. & Tak, P.P. Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: results of a phase II, randomized, placebo-controlled, dose-finding trial. Arthritis Rheum. 63, 1793-1803 (2011).
    • (2011) Arthritis Rheum. , vol.63 , pp. 1793-1803
    • Genovese, M.C.1    Kinnman, N.2    De La Bourdonnaye, G.3    Pena Rossi, C.4    Tak, P.P.5
  • 47
    • 0028328436 scopus 로고
    • Impaired immune and acute-phase responses in interleukin-6-deficient mice
    • Kopf, M. et al. Impaired immune and acute-phase responses in interleukin-6-deficient mice. Nature 368, 339-342 (1994).
    • (1994) Nature , vol.368 , pp. 339-342
    • Kopf, M.1
  • 48
    • 0030936275 scopus 로고    scopus 로고
    • B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation
    • Borriello, F. et al. B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation. Immunity 6, 303-313 (1997).
    • (1997) Immunity , vol.6 , pp. 303-313
    • Borriello, F.1
  • 49
    • 0025852445 scopus 로고
    • B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene
    • Kitamura, D., Roes, J., Kuhn, R. & Rajewsky, K.A. B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature 350, 423-426 (1991).
    • (1991) Nature , vol.350 , pp. 423-426
    • Kitamura, D.1    Roes, J.2    Kuhn, R.3    Rajewsky, K.A.4
  • 50
    • 0032851598 scopus 로고    scopus 로고
    • Genetic evidence for Lyn as a negative regulator of IL-4 signaling
    • Janas, M.L., Hodgkin, P., Hibbs, M. & Tarlinton, D. Genetic evidence for Lyn as a negative regulator of IL-4 signaling. J. Immunol. 163, 4192-4198 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 4192-4198
    • Janas, M.L.1    Hodgkin, P.2    Hibbs, M.3    Tarlinton, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.