-
1
-
-
0347499617
-
The role of eosinophils in host defense against helminth parasites
-
Klion AD, Nutman TB. The role of eosinophils in host defense against helminth parasites. J Allergy Clin Immunol. 2004; 113:30-37.
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 30-37
-
-
Klion, A.D.1
Nutman, T.B.2
-
2
-
-
34249053866
-
Eosinophils in the pathogenesis of allergic airways disease
-
Trivedi SG, Lloyd CM. Eosinophils in the pathogenesis of allergic airways disease. Cell Mol Life Sci. 2007; 64:1269-1289.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 1269-1289
-
-
Trivedi, S.G.1
Lloyd, C.M.2
-
4
-
-
64149122012
-
The hypereosinophilic syndromes: Current concepts and treatments
-
Gleich GJ, Leiferman KM. The hypereosinophilic syndromes: current concepts and treatments. Br J Haematol. 2009; 145:271-285.
-
(2009)
Br J Haematol
, vol.145
, pp. 271-285
-
-
Gleich, G.J.1
Leiferman, K.M.2
-
6
-
-
61849155730
-
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
-
Nair P, Pizzichini MM, Kjarsgaard M, Inman MD, Efthimiadis A, Pizzichini E, et al. Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N Engl J Med. 2009; 360:985-993.
-
(2009)
N Engl J Med
, vol.360
, pp. 985-993
-
-
Nair, P.1
Pizzichini, M.M.2
Kjarsgaard, M.3
Inman, M.D.4
Efthimiadis, A.5
Pizzichini, E.6
-
7
-
-
61849086181
-
Mepolizumab and exacerbations of refractory eosinophilic asthma
-
Haldar P, Brightling CE, Hargadon B, Gupta S, Monteiro W, Sousa A, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med. 2009; 360:973-984.
-
(2009)
N Engl J Med
, vol.360
, pp. 973-984
-
-
Haldar, P.1
Brightling, C.E.2
Hargadon, B.3
Gupta, S.4
Monteiro, W.5
Sousa, A.6
-
8
-
-
85047693849
-
Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
-
Flood-Page P, Menzies-Gow A, Phipps S, Ying S, Wangoo A, Ludwig MS, et al. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Invest. 2003; 112:1029-1036.
-
(2003)
J Clin Invest
, vol.112
, pp. 1029-1036
-
-
Flood-Page, P.1
Menzies-Gow, A.2
Phipps, S.3
Ying, S.4
Wangoo, A.5
Ludwig, M.S.6
-
9
-
-
4544274172
-
A critical role for eosinophils in allergic airways remodeling
-
Humbles AA, Lloyd CM, McMillan SJ, Friend DS, Xanthou G, McKenna EE, et al. A critical role for eosinophils in allergic airways remodeling. Science. 2004; 305:1776-1779.
-
(2004)
Science
, vol.305
, pp. 1776-1779
-
-
Humbles, A.A.1
Lloyd, C.M.2
McMillan, S.J.3
Friend, D.S.4
Xanthou, G.5
McKenna, E.E.6
-
10
-
-
77952753062
-
Eosinophil survival and apoptosis in health and disease
-
Park YM, Bochner BS. Eosinophil survival and apoptosis in health and disease. Allergy Asthma Immunol Res. 2010; 2:87-101.
-
(2010)
Allergy Asthma Immunol Res
, vol.2
, pp. 87-101
-
-
Park, Y.M.1
Bochner, B.S.2
-
11
-
-
84255210700
-
Molecular definitions of cell death subroutines: Recommendations of the nomenclature committee on cell death 2012
-
Galluzzi L, Vitale I, Abrams JM, Alnemri ES, Baehrecke EH, Blagosklonny MV, et al. Molecular definitions of cell death subroutines: recommendations of the nomenclature committee on cell death 2012. Cell Death Differ. 2012; 19:107-120.
-
(2012)
Cell Death Differ
, vol.19
, pp. 107-120
-
-
Galluzzi, L.1
Vitale, I.2
Abrams, J.M.3
Alnemri, E.S.4
Baehrecke, E.H.5
Blagosklonny, M.V.6
-
13
-
-
84876467969
-
Eosinophil apoptosis and clearance in asthma
-
Walsh G. Eosinophil apoptosis and clearance in asthma. J Cell Death. 2013; 6:17-25.
-
(2013)
J Cell Death
, vol.6
, pp. 17-25
-
-
Walsh, G.1
-
14
-
-
33747756534
-
Asthma: Defining of the persistent adult phenotypes
-
Wenzel SE. Asthma: defining of the persistent adult phenotypes. Lancet. 2006; 368:804-813.
-
(2006)
Lancet
, vol.368
, pp. 804-813
-
-
Wenzel, S.E.1
-
15
-
-
69249150516
-
T-helper type 2-driven inflammation defines major subphenotypes of asthma
-
Woodruff PG, Modrek B, Choy DF, Jia G, Abbas AR, Ellwanger A, et al. T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med. 2009; 180:388-395.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 388-395
-
-
Woodruff, P.G.1
Modrek, B.2
Choy, D.F.3
Jia, G.4
Abbas, A.R.5
Ellwanger, A.6
-
16
-
-
84868627139
-
Use of 111-indium-labeled autologous eosinophils to establish the in vivo kinetics of human eosinophils in healthy subjects
-
Farahi N, Singh NR, Heard S, Loutsios C, Summers C, Solanki CK, et al. Use of 111-indium-labeled autologous eosinophils to establish the in vivo kinetics of human eosinophils in healthy subjects. Blood. 2012; 120:4068-4071.
-
(2012)
Blood
, vol.120
, pp. 4068-4071
-
-
Farahi, N.1
Singh, N.R.2
Heard, S.3
Loutsios, C.4
Summers, C.5
Solanki, C.K.6
-
18
-
-
84891739424
-
Real-time differential tracking of human neutrophil and eosinophil migration in vivo
-
Lukawska JJ, Livieratos L, Sawyer BM, Lee T, O'Doherty M, Blower PJ, et al. Real-time differential tracking of human neutrophil and eosinophil migration in vivo. J Allergy Clin Immunol. 2014; 133:233-239.
-
(2014)
J Allergy Clin Immunol
, vol.133
, pp. 233-239
-
-
Lukawska, J.J.1
Livieratos, L.2
Sawyer, B.M.3
Lee, T.4
O'Doherty, M.5
Blower, P.J.6
-
19
-
-
77956537363
-
Flow cytometric profiles, biomolecular and morphological aspects of transfixed leukocytes and red cells
-
Canonico B, Betti M, Luchetti F, Battistelli M, Falcieri E, Ferri P, et al. Flow cytometric profiles, biomolecular and morphological aspects of transfixed leukocytes and red cells. Cytometry B Clin Cytom. 2010; 78:267-278.
-
(2010)
Cytometry B Clin Cytom
, vol.78
, pp. 267-278
-
-
Canonico, B.1
Betti, M.2
Luchetti, F.3
Battistelli, M.4
Falcieri, E.5
Ferri, P.6
-
20
-
-
49249130983
-
Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils
-
Zimmermann N, McBride ML, Yamada Y, Hudson SA, Jones C, Cromie KD, et al. Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils. Allergy. 2008; 63:1156-1163.
-
(2008)
Allergy
, vol.63
, pp. 1156-1163
-
-
Zimmermann, N.1
McBride, M.L.2
Yamada, Y.3
Hudson, S.A.4
Jones, C.5
Cromie, K.D.6
-
21
-
-
0034693075
-
Enhancement of human eosinophil apoptosis by fluticasone propionate, budesonide, and beclomethasone
-
Zhang X, Moilanen E, Kankaanranta H. Enhancement of human eosinophil apoptosis by fluticasone propionate, budesonide, and beclomethasone. Eur J Pharmacol. 2000; 406:325-332.
-
(2000)
Eur J Pharmacol
, vol.406
, pp. 325-332
-
-
Zhang, X.1
Moilanen, E.2
Kankaanranta, H.3
-
22
-
-
0037119038
-
Divergent effect of mometasone on human eosinophil and neutrophil apoptosis
-
Zhang X, Moilanen E, Adcock IM, Lindsay MA, Kankaanranta H. Divergent effect of mometasone on human eosinophil and neutrophil apoptosis. Life Sci. 2002; 71:1523-1534.
-
(2002)
Life Sci
, vol.71
, pp. 1523-1534
-
-
Zhang, X.1
Moilanen, E.2
Adcock, I.M.3
Lindsay, M.A.4
Kankaanranta, H.5
-
23
-
-
0026075046
-
Glucocorticoids inhibit eosinophil responses to granulocyte-macrophage colony-stimulating factor
-
Lamas AM, Leon OG, Schleimer RP. Glucocorticoids inhibit eosinophil responses to granulocyte-macrophage colony-stimulating factor. J Immunol. 1991; 147:254-259.
-
(1991)
J Immunol
, vol.147
, pp. 254-259
-
-
Lamas, A.M.1
Leon, O.G.2
Schleimer, R.P.3
-
24
-
-
0025841768
-
Glucocorticoids inhibit cytokine-mediated eosinophil survival
-
Wallen N, Kita H, Weiler D, Gleich GJ. Glucocorticoids inhibit cytokine-mediated eosinophil survival. J Immunol. 1991; 147:3490-3495.
-
(1991)
J Immunol
, vol.147
, pp. 3490-3495
-
-
Wallen, N.1
Kita, H.2
Weiler, D.3
Gleich, G.J.4
-
25
-
-
0034047709
-
Leukotriene receptor antagonists and synthesis inhibitors reverse survival in eosinophils of asthmatic individuals
-
Lee E, Robertson T, Smith J, Kilfeather S. Leukotriene receptor antagonists and synthesis inhibitors reverse survival in eosinophils of asthmatic individuals. Am J Respir Crit Care Med. 2000; 161:1881-1886.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 1881-1886
-
-
Lee, E.1
Robertson, T.2
Smith, J.3
Kilfeather, S.4
-
26
-
-
0030984157
-
Theophylline accelerates human granulocyte apoptosis not via phosphodiesterase inhibition
-
Yasui K, Hu B, Nakazawa T, Agematsu K, Komiyama A. Theophylline accelerates human granulocyte apoptosis not via phosphodiesterase inhibition. J Clin Invest. 1997; 100:1677-1684.
-
(1997)
J Clin Invest
, vol.100
, pp. 1677-1684
-
-
Yasui, K.1
Hu, B.2
Nakazawa, T.3
Agematsu, K.4
Komiyama, A.5
-
27
-
-
0842321788
-
Extremely rapid and intense induction of apoptosis in human eosinophils by anti-CD30 antibody treatment in vitro
-
Matsumoto K., Terakawa M., Miura K., Fukuda S., Nakajima T., Saito H. Extremely rapid and intense induction of apoptosis in human eosinophils by anti-CD30 antibody treatment in vitro. J Immunol. 2004; 172:2186-2193.
-
(2004)
J Immunol
, vol.172
, pp. 2186-2193
-
-
Matsumoto, K.1
Terakawa, M.2
Miura, K.3
Fukuda, S.4
Nakajima, T.5
Saito, H.6
-
28
-
-
0030035298
-
Eosinophil apoptosis and the resolution of airway inflammation in asthma
-
Woolley KL, Gibson PG, Carty K, Wilson AJ, Twaddell SH, Woolley MJ. Eosinophil apoptosis and the resolution of airway inflammation in asthma. Am J Respir Crit Care Med. 1996; 154:237-243.
-
(1996)
Am J Respir Crit Care Med
, vol.154
, pp. 237-243
-
-
Woolley, K.L.1
Gibson, P.G.2
Carty, K.3
Wilson, A.J.4
Twaddell, S.H.5
Woolley, M.J.6
-
29
-
-
0032209561
-
Apoptosis, proliferation, and expression of Bcl-2, Fas, and Fas ligand in bronchial biopsies from asthmatics
-
Druilhe A, Wallaert B, Tsicopoulos A, Lapa e Silva JR, Tillie-Leblond I, Tonnel AB, et al. Apoptosis, proliferation, and expression of Bcl-2, Fas, and Fas ligand in bronchial biopsies from asthmatics. Am J Respir Cell Mol Biol. 1998; 19: 747-757.
-
(1998)
Am J Respir Cell Mol Biol
, vol.19
, pp. 747-757
-
-
Druilhe, A.1
Wallaert, B.2
Tsicopoulos, A.3
Lapae Silva, J.R.4
Tillie-Leblond, I.5
Tonnel, A.B.6
-
30
-
-
0033060178
-
Evaluation of apoptosis of eosinophils, macrophages, and T lymphocytes in mucosal biopsy specimens of patients with asthma and chronic bronchitis
-
Vignola AM, Chanez P, Chiappara G, Siena L, Merendino A, Reina C, et al. Evaluation of apoptosis of eosinophils, macrophages, and T lymphocytes in mucosal biopsy specimens of patients with asthma and chronic bronchitis. J Allergy Clin Immunol. 1999; 103:563-573.
-
(1999)
J Allergy Clin Immunol
, vol.103
, pp. 563-573
-
-
Vignola, A.M.1
Chanez, P.2
Chiappara, G.3
Siena, L.4
Merendino, A.5
Reina, C.6
-
31
-
-
0043142517
-
Reduced eosinophil apoptosis in induced sputum correlates with asthma severity
-
Duncan CJ, Lawrie A, Blaylock MG, Douglas JG, Walsh GM. Reduced eosinophil apoptosis in induced sputum correlates with asthma severity. Eur Respir J. 2003; 22:484-490.
-
(2003)
Eur Respir J
, vol.22
, pp. 484-490
-
-
Duncan, C.J.1
Lawrie, A.2
Blaylock, M.G.3
Douglas, J.G.4
Walsh, G.M.5
-
32
-
-
0031943598
-
Airway epithelial Fas ligand expression: Potential role in modulating bronchial inflammation
-
Gochuico BR, Miranda KM, Hessel EM, De Bie JJ, Van Oosterhout AJ, Cruikshank WW, et al. Airway epithelial Fas ligand expression: potential role in modulating bronchial inflammation. Am J Physiol. 1998; 274:L444-L449.
-
(1998)
Am J Physiol
, vol.274
-
-
Gochuico, B.R.1
Miranda, K.M.2
Hessel, E.M.3
de Bie, J.J.4
van Oosterhout, A.J.5
Cruikshank, W.W.6
-
33
-
-
66149175695
-
T cells and eosinophils in bronchial smooth muscle cell death in asthma
-
Solarewicz-Madejek K, Basinski TM, Crameri R, Akdis M, Akkaya A, Blaser K, et al. T cells and eosinophils in bronchial smooth muscle cell death in asthma. Clin Exp Allergy. 2009; 39:845-855.
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 845-855
-
-
Solarewicz-Madejek, K.1
Basinski, T.M.2
Crameri, R.3
Akdis, M.4
Akkaya, A.5
Blaser, K.6
-
34
-
-
40049085568
-
Increased T-cell survival by structural bronchial cells derived from asthmatic subjects cultured in an engineered human mucosa
-
Darveau ME, Jacques E, Rouabhia M, Hamid Q, Chakir J. Increased T-cell survival by structural bronchial cells derived from asthmatic subjects cultured in an engineered human mucosa. J Allergy Clin Immunol. 2008; 121:692-699.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 692-699
-
-
Darveau, M.E.1
Jacques, E.2
Rouabhia, M.3
Hamid, Q.4
Chakir, J.5
-
35
-
-
0031787176
-
Role of T-helper type 2 cytokines in down-modulation of Fas mRNA and receptor on the surface of activated CD4(+) T cells: Molecular basis for the persistence of the allergic immune response
-
Spinozzi F, Agea E, Fizzotti M, Bassotti G, Russano A, Droetto S, et al. Role of T-helper type 2 cytokines in down-modulation of Fas mRNA and receptor on the surface of activated CD4(+) T cells: molecular basis for the persistence of the allergic immune response. FASEB J. 1998; 12:1747-1753.
-
(1998)
FASEB J
, vol.12
, pp. 1747-1753
-
-
Spinozzi, F.1
Agea, E.2
Fizzotti, M.3
Bassotti, G.4
Russano, A.5
Droetto, S.6
-
36
-
-
84857195755
-
Systemic FasL neutralization increases eosinophilic inflammation in a mouse model of asthma
-
Sharma SK, Almeida FA, Kierstein S, Hortobagyi L, Lin T, Larkin A, et al. Systemic FasL neutralization increases eosinophilic inflammation in a mouse model of asthma. Allergy. 2012; 67:328-335.
-
(2012)
Allergy
, vol.67
, pp. 328-335
-
-
Sharma, S.K.1
Almeida, F.A.2
Kierstein, S.3
Hortobagyi, L.4
Lin, T.5
Larkin, A.6
-
37
-
-
26244464292
-
Anti-Fas mAb-induced apoptosis and cytolysis of airway tissue eosinophils aggravates rather than resolves established inflammation
-
Uller L, Rydell-Tormanen K, Persson CG, Erjefalt JS. Anti-Fas mAb-induced apoptosis and cytolysis of airway tissue eosinophils aggravates rather than resolves established inflammation. Respir Res. 2005; 6:90.
-
(2005)
Respir Res
, vol.6
, pp. 90
-
-
Uller, L.1
Rydell-Tormanen, K.2
Persson, C.G.3
Erjefalt, J.S.4
-
38
-
-
0026610142
-
Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma
-
Robinson DS, Hamid Q, Ying S, Tsicopoulos A, Barkans J, Bentley AM, et al. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med. 1992; 326:298-304.
-
(1992)
N Engl J Med
, vol.326
, pp. 298-304
-
-
Robinson, D.S.1
Hamid, Q.2
Ying, S.3
Tsicopoulos, A.4
Barkans, J.5
Bentley, A.M.6
-
39
-
-
0031723068
-
Granulocyte macrophage colony-stimulating factor is the main cytokine enhancing survival of eosinophils in asthmatic airways
-
Park CS, Choi YS, Ki SY, Moon SH, Jeong SW, Uh ST, et al. Granulocyte macrophage colony-stimulating factor is the main cytokine enhancing survival of eosinophils in asthmatic airways. Eur Respir J. 1998; 12:872-878.
-
(1998)
Eur Respir J
, vol.12
, pp. 872-878
-
-
Park, C.S.1
Choi, Y.S.2
Ki, S.Y.3
Moon, S.H.4
Jeong, S.W.5
Uh, S.T.6
-
40
-
-
0028907399
-
Eosinophil viabilityenhancing activity in sputum from patients with bronchial asthma, contributions of interleukin-5 and granulocyte/macrophage colony-stimulating factor
-
Adachi T, Motojima S, Hirata A, Fukuda T, Makino S. Eosinophil viabilityenhancing activity in sputum from patients with bronchial asthma, contributions of interleukin-5 and granulocyte/macrophage colony-stimulating factor. Am J Respir Crit Care Med. 1995; 151:618-623.
-
(1995)
Am J Respir Crit Care Med
, vol.151
, pp. 618-623
-
-
Adachi, T.1
Motojima, S.2
Hirata, A.3
Fukuda, T.4
Makino, S.5
-
41
-
-
0025769977
-
Effects of IL-5, granulocyte/macrophage colony-stimulating factor (GM-CSF) and IL-3 on the survival of human blood eosinophils in vitro
-
Tai PC, Sun L, Spry CJ. Effects of IL-5, granulocyte/macrophage colony-stimulating factor (GM-CSF) and IL-3 on the survival of human blood eosinophils in vitro. Clin Exp Immunol. 1991; 85:312-316.
-
(1991)
Clin Exp Immunol
, vol.85
, pp. 312-316
-
-
Tai, P.C.1
Sun, L.2
Spry, C.J.3
-
42
-
-
0028953733
-
Interleukin-5 signaling in human eosinophils involves JAK2 tyrosine kinase and Stat1 alpha
-
van der Bruggen T, Caldenhoven E, Kanters D, Coffer P, Raaijmakers JA, Lammers JW, et al. Interleukin-5 signaling in human eosinophils involves JAK2 tyrosine kinase and Stat1 alpha. Blood. 1995; 85:1442-1448.
-
(1995)
Blood
, vol.85
, pp. 1442-1448
-
-
van der Bruggen, T.1
Caldenhoven, E.2
Kanters, D.3
Coffer, P.4
Raaijmakers, J.A.5
Lammers, J.W.6
-
43
-
-
0029913802
-
Requirement of lyn and syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils
-
Yousefi S, Hoessli DC, Blaser K, Mills GB, Simon HU. Requirement of lyn and syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils. J Exp Med. 1996; 183:1407-1414.
-
(1996)
J Exp Med
, vol.183
, pp. 1407-1414
-
-
Yousefi, S.1
Hoessli, D.C.2
Blaser, K.3
Mills, G.B.4
Simon, H.U.5
-
44
-
-
0032479926
-
Lyn, Jak2, and raf-1 kinases are critical for the antiapoptotic effect of interleukin 5, whereas only raf-1 kinase is essential for eosinophil activation and degranulation
-
Pazdrak K, Olszewska-Pazdrak B, Stafford S, Garofalo RP, Alam R. Lyn, Jak2, and raf-1 kinases are critical for the antiapoptotic effect of interleukin 5, whereas only raf-1 kinase is essential for eosinophil activation and degranulation. J Exp Med. 1998; 188:421-429.
-
(1998)
J Exp Med
, vol.188
, pp. 421-429
-
-
Pazdrak, K.1
Olszewska-Pazdrak, B.2
Stafford, S.3
Garofalo, R.P.4
Alam, R.5
-
45
-
-
33751530020
-
IL-5-mediated eosinophil survival requires inhibition of GSK-3 and correlates with beta-catenin relocalization
-
Rosas M, Dijkers PF, Lindemans CL, Lammers JW, Koenderman L, Coffer PJ. IL-5-mediated eosinophil survival requires inhibition of GSK-3 and correlates with beta-catenin relocalization. J Leukoc Biol. 2006; 80:186-195.
-
(2006)
J Leukoc Biol
, vol.80
, pp. 186-195
-
-
Rosas, M.1
Dijkers, P.F.2
Lindemans, C.L.3
Lammers, J.W.4
Koenderman, L.5
Coffer, P.J.6
-
46
-
-
0028956998
-
The intracellular signal transduction mechanism of interleukin 5 in eosinophils: The involvement of lyn tyrosine kinase and the ras-raf-1-MEK-microtubule-associated protein kinase pathway
-
Pazdrak K, Schreiber D, Forsythe P, Justement L, Alam R. The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the ras-raf-1-MEK-microtubule-associated protein kinase pathway. J Exp Med. 1995; 181:1827-1834.
-
(1995)
J Exp Med
, vol.181
, pp. 1827-1834
-
-
Pazdrak, K.1
Schreiber, D.2
Forsythe, P.3
Justement, L.4
Alam, R.5
-
47
-
-
0029058148
-
The activation of the jak-STAT 1 signaling pathway by IL-5 in eosinophils
-
Pazdrak K, Stafford S, Alam R. The activation of the jak-STAT 1 signaling pathway by IL-5 in eosinophils. J Immunol. 1995; 155:397-402.
-
(1995)
J Immunol
, vol.155
, pp. 397-402
-
-
Pazdrak, K.1
Stafford, S.2
Alam, R.3
-
48
-
-
0032055541
-
Analysis of signal transduction pathways in human eosinophils activated by chemoattractants and the T-helper 2-derived cytokines interleukin-4 and interleukin- 5
-
Coffer PJ, Schweizer RC, Dubois GR, Maikoe T, Lammers JW, Koenderman L. Analysis of signal transduction pathways in human eosinophils activated by chemoattractants and the T-helper 2-derived cytokines interleukin-4 and interleukin- 5. Blood. 1998; 91:2547-2557.
-
(1998)
Blood
, vol.91
, pp. 2547-2557
-
-
Coffer, P.J.1
Schweizer, R.C.2
Dubois, G.R.3
Maikoe, T.4
Lammers, J.W.5
Koenderman, L.6
-
49
-
-
60749100315
-
The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation
-
Shen ZJ, Esnault S, Schinzel A, Borner C, Malter JS. The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation. Nat Immunol. 2009; 10:257-265.
-
(2009)
Nat Immunol
, vol.10
, pp. 257-265
-
-
Shen, Z.J.1
Esnault, S.2
Schinzel, A.3
Borner, C.4
Malter, J.S.5
-
50
-
-
0032763790
-
SB 203580, an inhibitor of p38 mitogen-activated protein kinase, enhances constitutive apoptosis of cytokine-deprived human eosinophils
-
Kankaanranta H, De Souza PM, Barnes PJ, Salmon M, Giembycz MA, Lindsay MA. SB 203580, an inhibitor of p38 mitogen-activated protein kinase, enhances constitutive apoptosis of cytokine-deprived human eosinophils. J Pharmacol Exp Ther. 1999; 290:621-628.
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 621-628
-
-
Kankaanranta, H.1
de Souza, P.M.2
Barnes, P.J.3
Salmon, M.4
Giembycz, M.A.5
Lindsay, M.A.6
-
51
-
-
0032934674
-
Involvement of JAK2, but not PI 3-kinase/Akt and MAP kinase pathways, in antiapoptotic signals of GM-CSF in human eosinophils
-
Miike S, Nakao A, Hiraguri M, Kurasawa K, Saito Y, Iwamoto I. Involvement of JAK2, but not PI 3-kinase/Akt and MAP kinase pathways, in antiapoptotic signals of GM-CSF in human eosinophils. J Leukoc Biol. 1999; 65: 700-706.
-
(1999)
J Leukoc Biol
, vol.65
, pp. 700-706
-
-
Miike, S.1
Nakao, A.2
Hiraguri, M.3
Kurasawa, K.4
Saito, Y.5
Iwamoto, I.6
-
52
-
-
0035496905
-
Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release, and activation of caspases in human eosinophils
-
Dewson G, Cohen GM, Wardlaw AJ. Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release, and activation of caspases in human eosinophils. Blood. 2001; 98:2239-2247.
-
(2001)
Blood
, vol.98
, pp. 2239-2247
-
-
Dewson, G.1
Cohen, G.M.2
Wardlaw, A.J.3
-
53
-
-
0028040125
-
Transforming growth factor beta abrogates the effects of hematopoietins on eosinophils and induces their apoptosis
-
Alam R, Forsythe P, Stafford S, Fukuda Y. Transforming growth factor beta abrogates the effects of hematopoietins on eosinophils and induces their apoptosis. J Exp Med. 1994; 179:1041-1045.
-
(1994)
J Exp Med
, vol.179
, pp. 1041-1045
-
-
Alam, R.1
Forsythe, P.2
Stafford, S.3
Fukuda, Y.4
-
54
-
-
0028881246
-
Mechanism of inhibition of eosinophil activation by transforming growth factor-beta. Inhibition of Lyn, MAP, Jak2 kinases and STAT1 nuclear factor
-
Pazdrak K, Justement L, Alam R. Mechanism of inhibition of eosinophil activation by transforming growth factor-beta. Inhibition of Lyn, MAP, Jak2 kinases and STAT1 nuclear factor. J Immunol. 1995; 155:4454-4458.
-
(1995)
J Immunol
, vol.155
, pp. 4454-4458
-
-
Pazdrak, K.1
Justement, L.2
Alam, R.3
-
55
-
-
84896730626
-
Transforming growth factor-1 antagonizes interleukin-5 pro-survival signaling by activating calpain-1 in primary human eosinophils
-
Xie Q, Shen ZJ, Oh J, Chu H, Malter JS. Transforming growth factor-1 antagonizes interleukin-5 pro-survival signaling by activating calpain-1 in primary human eosinophils. J Clin Cell Immunol. 2011; (Suppl 1):003.
-
(2011)
J Clin Cell Immunol
, Issue.SUPPL. 1
, pp. 003
-
-
Xie, Q.1
Shen, Z.J.2
Oh, J.3
Chu, H.4
Malter, J.S.5
-
56
-
-
0033941414
-
Delayed eosinophil apoptosis in asthma
-
Kankaanranta H, Lindsay MA, Giembycz MA, Zhang X, Moilanen E, Barnes PJ. Delayed eosinophil apoptosis in asthma. J Allergy Clin Immunol. 2000; 106:77-83.
-
(2000)
J Allergy Clin Immunol
, vol.106
, pp. 77-83
-
-
Kankaanranta, H.1
Lindsay, M.A.2
Giembycz, M.A.3
Zhang, X.4
Moilanen, E.5
Barnes, P.J.6
-
57
-
-
0031569468
-
Direct demonstration of delayed eosinophil apoptosis as a mechanism causing tissue eosinophilia
-
Simon HU, Yousefi S, Schranz C, Schapowal A, Bachert C, Blaser K. Direct demonstration of delayed eosinophil apoptosis as a mechanism causing tissue eosinophilia. J Immunol. 1997; 158:3902-3908.
-
(1997)
J Immunol
, vol.158
, pp. 3902-3908
-
-
Simon, H.U.1
Yousefi, S.2
Schranz, C.3
Schapowal, A.4
Bachert, C.5
Blaser, K.6
-
58
-
-
0036551325
-
Interleukin-15 inhibits spontaneous apoptosis in human eosinophils via autocrine production of granulocyte macrophage-colony stimulating factor and nuclear factor-kappa B activation
-
Hoontrakoon R, Chu HW, Gardai SJ, Wenzel SE, McDonald P, Fadok VA, et al. Interleukin-15 inhibits spontaneous apoptosis in human eosinophils via autocrine production of granulocyte macrophage-colony stimulating factor and nuclear factor-kappa B activation. Am J Respir Cell Mol Biol. 2002; 26: 404-412.
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 404-412
-
-
Hoontrakoon, R.1
Chu, H.W.2
Gardai, S.J.3
Wenzel, S.E.4
McDonald, P.5
Fadok, V.A.6
-
59
-
-
34547860034
-
Leptin-mediated cytokine release and migration of eosinophils: Implications for immunopathophysiology of allergic inflammation
-
Wong CK, Cheung PF, Lam CW. Leptin-mediated cytokine release and migration of eosinophils: implications for immunopathophysiology of allergic inflammation. Eur J Immunol. 2007; 37:2337-2348.
-
(2007)
Eur J Immunol
, vol.37
, pp. 2337-2348
-
-
Wong, C.K.1
Cheung, P.F.2
Lam, C.W.3
-
60
-
-
0035822270
-
Mechanism of tumour necrosis factor alpha mediated eosinophil survival
-
Temkin V, Levi-Schaffer F. Mechanism of tumour necrosis factor alpha mediated eosinophil survival. Cytokine. 2001; 15:20-26.
-
(2001)
Cytokine
, vol.15
, pp. 20-26
-
-
Temkin, V.1
Levi-Schaffer, F.2
-
61
-
-
77956633109
-
Thymic stromal lymphopoietin induces chemotactic and prosurvival effects in eosinophils: Implications in allergic inflammation
-
Wong CK, Hu S, Cheung PF, Lam CW. Thymic stromal lymphopoietin induces chemotactic and prosurvival effects in eosinophils: implications in allergic inflammation. Am J Respir Cell Mol Biol. 2010; 43:305-315.
-
(2010)
Am J Respir Cell Mol Biol
, vol.43
, pp. 305-315
-
-
Wong, C.K.1
Hu, S.2
Cheung, P.F.3
Lam, C.W.4
-
62
-
-
3242745070
-
Allergen activates peripheral blood eosinophil nuclear factor-kappa B to generate granulocyte macrophage-colony stimulating factor, tumour necrosis factor-alpha and interleukin- 8
-
Coward WR, Sagara H, Wilson SJ, Holgate ST, Church MK. Allergen activates peripheral blood eosinophil nuclear factor-kappa B to generate granulocyte macrophage-colony stimulating factor, tumour necrosis factor-alpha and interleukin- 8. Clin Exp Allergy. 2004; 34:1071-1078.
-
(2004)
Clin Exp Allergy
, vol.34
, pp. 1071-1078
-
-
Coward, W.R.1
Sagara, H.2
Wilson, S.J.3
Holgate, S.T.4
Church, M.K.5
-
63
-
-
34249814066
-
Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils
-
Wong CK, Cheung PF, Ip WK, Lam CW. Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils. Am J Respir Cell Mol Biol. 2007; 37:85-96.
-
(2007)
Am J Respir Cell Mol Biol
, vol.37
, pp. 85-96
-
-
Wong, C.K.1
Cheung, P.F.2
Ip, W.K.3
Lam, C.W.4
-
64
-
-
67349207937
-
Bacterial DNA delays human eosinophil apoptosis
-
Ilmarinen P, Hasala H, Sareila O, Moilanen E, Kankaanranta H. Bacterial DNA delays human eosinophil apoptosis. Pulm Pharmacol Ther. 2009; 22:167-176.
-
(2009)
Pulm Pharmacol Ther
, vol.22
, pp. 167-176
-
-
Ilmarinen, P.1
Hasala, H.2
Sareila, O.3
Moilanen, E.4
Kankaanranta, H.5
-
65
-
-
84890794285
-
Eosinophil apoptosis as a therapeutic target in allergic asthma
-
Ilmarinen P, Kankaanranta H. Eosinophil apoptosis as a therapeutic target in allergic asthma. Basic Clin Pharmacol Toxicol. 2014; 114(1):109-117.
-
(2014)
Basic Clin Pharmacol Toxicol
, vol.114
, Issue.1
, pp. 109-117
-
-
Ilmarinen, P.1
Kankaanranta, H.2
-
66
-
-
10444249499
-
Inhibition of NF-kappa B by a cell permeable form of I kappa B alpha induces apoptosis in eosinophils
-
Fujihara S, Jaffray E, Farrow SN, Rossi AG, Haslett C, Hay RT. Inhibition of NF-kappa B by a cell permeable form of I kappa B alpha induces apoptosis in eosinophils. Biochem Biophys Res Commun. 2005; 326:632-637.
-
(2005)
Biochem Biophys Res Commun
, vol.326
, pp. 632-637
-
-
Fujihara, S.1
Jaffray, E.2
Farrow, S.N.3
Rossi, A.G.4
Haslett, C.5
Hay, R.T.6
-
67
-
-
0032104031
-
Mast cells enhance eosinophil survival in vitro: Role of TNF-alpha and granulocyte-macrophage colony-stimulating factor
-
Levi-Schaffer F, Temkin V, Malamud V, Feld S, Zilberman Y. Mast cells enhance eosinophil survival in vitro: role of TNF-alpha and granulocyte-macrophage colony-stimulating factor. J Immunol. 1998; 160:5554-5562.
-
(1998)
J Immunol
, vol.160
, pp. 5554-5562
-
-
Levi-Schaffer, F.1
Temkin, V.2
Malamud, V.3
Feld, S.4
Zilberman, Y.5
-
68
-
-
0028927826
-
Effect of IL-4 and interferon-gamma (IFN-gamma) on IL-3- and IL-5-induced eosinophil differentiation from human cord blood mononuclear cells
-
Ochiai K, Iwamoto I, Takahashi H, Yoshida S, Tomioka H, Yoshida S. Effect of IL-4 and interferon-gamma (IFN-gamma) on IL-3- and IL-5-induced eosinophil differentiation from human cord blood mononuclear cells. Clin Exp Immunol. 1995; 99:124-128.
-
(1995)
Clin Exp Immunol
, vol.99
, pp. 124-128
-
-
Ochiai, K.1
Iwamoto, I.2
Takahashi, H.3
Yoshida, S.4
Tomioka, H.5
Yoshida, S.6
-
69
-
-
0025166115
-
Effects of IFN on human eosinophils in comparison with other cytokines. A novel class of eosinophil activators with delayed onset of action
-
Valerius T, Repp R, Kalden JR, Platzer E. Effects of IFN on human eosinophils in comparison with other cytokines. A novel class of eosinophil activators with delayed onset of action. J Immunol. 1990; 145:2950-2958.
-
(1990)
J Immunol
, vol.145
, pp. 2950-2958
-
-
Valerius, T.1
Repp, R.2
Kalden, J.R.3
Platzer, E.4
-
71
-
-
0036736789
-
CD40 engagement enhances eosinophil survival through induction of cellular inhibitor of apoptosis protein 2 expression: Possible involvement in allergic inflammation
-
Bureau F, Seumois G, Jaspar F, Vanderplasschen A, Detry B, Pastoret PP, et al. CD40 engagement enhances eosinophil survival through induction of cellular inhibitor of apoptosis protein 2 expression: possible involvement in allergic inflammation. J Allergy Clin Immunol. 2002; 110:443-449.
-
(2002)
J Allergy Clin Immunol
, vol.110
, pp. 443-449
-
-
Bureau, F.1
Seumois, G.2
Jaspar, F.3
Vanderplasschen, A.4
Detry, B.5
Pastoret, P.P.6
-
72
-
-
0032521148
-
Disruption of antigen-induced inflammatory responses in CD40 ligand knockout mice
-
Lei XF, Ohkawara Y, Stampfli MR, Mastruzzo C, Marr RA, Snider D, et al. Disruption of antigen-induced inflammatory responses in CD40 ligand knockout mice. J Clin Invest. 1998; 101:1342-1353.
-
(1998)
J Clin Invest
, vol.101
, pp. 1342-1353
-
-
Lei, X.F.1
Ohkawara, Y.2
Stampfli, M.R.3
Mastruzzo, C.4
Marr, R.A.5
Snider, D.6
-
73
-
-
84865293522
-
Nitric oxideinduced eosinophil apoptosis is dependent on mitochondrial permeability transition (mPT), JNK and oxidative stress: Apoptosis is preceded but not mediated by early mPT-dependent JNK activation
-
Ilmarinen-Salo P, Moilanen E, Kinnula VL, Kankaanranta H. Nitric oxideinduced eosinophil apoptosis is dependent on mitochondrial permeability transition (mPT), JNK and oxidative stress: apoptosis is preceded but not mediated by early mPT-dependent JNK activation. Respir Res. 2012; 13:73.
-
(2012)
Respir Res
, vol.13
, pp. 73
-
-
Ilmarinen-Salo, P.1
Moilanen, E.2
Kinnula, V.L.3
Kankaanranta, H.4
-
74
-
-
0036097582
-
Caspase activation in the absence of mitochondrial changes in granulocyte apoptosis
-
Nopp A, Lundahl J, Stridh H. Caspase activation in the absence of mitochondrial changes in granulocyte apoptosis. Clin Exp Immunol. 2002; 128:267-274.
-
(2002)
Clin Exp Immunol
, vol.128
, pp. 267-274
-
-
Nopp, A.1
Lundahl, J.2
Stridh, H.3
-
75
-
-
77953229988
-
Nitric oxide induces apoptosis in GM-CSF-treated eosinophils via caspase-6-dependent lamin and DNA fragmentation
-
Ilmarinen-Salo P, Moilanen E, Kankaanranta H. Nitric oxide induces apoptosis in GM-CSF-treated eosinophils via caspase-6-dependent lamin and DNA fragmentation. Pulm Pharmacol Ther. 2010; 23:365-371.
-
(2010)
Pulm Pharmacol Ther
, vol.23
, pp. 365-371
-
-
Ilmarinen-Salo, P.1
Moilanen, E.2
Kankaanranta, H.3
-
76
-
-
67649386799
-
Sequence of physical changes to the cell membrane during glucocorticoidinduced apoptosis in S49 lymphoma cells
-
Bailey RW, Nguyen T, Robertson L, Gibbons E, Nelson J, Christensen RE, et al. Sequence of physical changes to the cell membrane during glucocorticoidinduced apoptosis in S49 lymphoma cells. Biophys J. 2009; 96:2709-2718.
-
(2009)
Biophys J
, vol.96
, pp. 2709-2718
-
-
Bailey, R.W.1
Nguyen, T.2
Robertson, L.3
Gibbons, E.4
Nelson, J.5
Christensen, R.E.6
-
77
-
-
0034916694
-
The trigger to cell death determines the efficiency with which dying cells are cleared by neighbours
-
Wiegand UK, Corbach S, Prescott AR, Savill J, Spruce BA. The trigger to cell death determines the efficiency with which dying cells are cleared by neighbours. Cell Death Differ. 2001; 8:734-746.
-
(2001)
Cell Death Differ
, vol.8
, pp. 734-746
-
-
Wiegand, U.K.1
Corbach, S.2
Prescott, A.R.3
Savill, J.4
Spruce, B.A.5
-
78
-
-
0036362584
-
Kinetics of apoptotic markers in exogeneously induced apoptosis of EL4 cells
-
Jessel R, Haertel S, Socaciu C, Tykhonova S, Diehl HA. Kinetics of apoptotic markers in exogeneously induced apoptosis of EL4 cells. J Cell Mol Med. 2002; 6:82-92.
-
(2002)
J Cell Mol Med
, vol.6
, pp. 82-92
-
-
Jessel, R.1
Haertel, S.2
Socaciu, C.3
Tykhonova, S.4
Diehl, H.A.5
-
79
-
-
33644925825
-
Annexin A5 inhibits engulfment through internalization of PS-expressing cell membrane patches
-
Kenis H, van Genderen H, Deckers NM, Lux PA, Hofstra L, Narula J, et al. Annexin A5 inhibits engulfment through internalization of PS-expressing cell membrane patches. Exp Cell Res. 2006; 312:719-726.
-
(2006)
Exp Cell Res
, vol.312
, pp. 719-726
-
-
Kenis, H.1
van Genderen, H.2
Deckers, N.M.3
Lux, P.A.4
Hofstra, L.5
Narula, J.6
-
80
-
-
84885410221
-
Various methods available for detection of apoptotic cells-a review
-
Archana M, Bastian, Yogesh TL, Kumaraswamy KL. Various methods available for detection of apoptotic cells-a review. Indian J Cancer. 2013; 50:274-283.
-
(2013)
Indian J Cancer
, vol.50
, pp. 274-283
-
-
Archana, M.1
Bastian Yogesh, T.L.2
Kumaraswamy, K.L.3
-
81
-
-
84872250952
-
Cytometry of apoptosis. Historical perspective and new advances
-
Wlodkowic D, Skommer J, Darzynkiewicz Z. Cytometry of apoptosis. Historical perspective and new advances. Exp Oncol. 2012; 34:255-262.
-
(2012)
Exp Oncol
, vol.34
, pp. 255-262
-
-
Wlodkowic, D.1
Skommer, J.2
Darzynkiewicz, Z.3
-
83
-
-
77956095537
-
Mitochondria and cell death: Outer membrane permeabilization and beyond
-
Tait SW, Green DR. Mitochondria and cell death: outer membrane permeabilization and beyond. Nat Rev Mol Cell Biol. 2010; 11:621-632.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 621-632
-
-
Tait, S.W.1
Green, D.R.2
-
84
-
-
34948813599
-
Bid activation during induction of extrinsic and intrinsic apoptosis in eosinophils
-
Segal M, Niazi S, Simons MP, Galati SA, Zangrilli JG. Bid activation during induction of extrinsic and intrinsic apoptosis in eosinophils. Immunol Cell Biol. 2007; 85:518-524.
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 518-524
-
-
Segal, M.1
Niazi, S.2
Simons, M.P.3
Galati, S.A.4
Zangrilli, J.G.5
-
85
-
-
66949179732
-
A role for bid in eosinophil apoptosis and in allergic airway reaction
-
Maret M, Ruffie C, Letuve S, Phelep A, Thibaudeau O, Marchal J, et al. A role for bid in eosinophil apoptosis and in allergic airway reaction. J Immunol. 2009; 182:5740-5747.
-
(2009)
J Immunol
, vol.182
, pp. 5740-5747
-
-
Maret, M.1
Ruffie, C.2
Letuve, S.3
Phelep, A.4
Thibaudeau, O.5
Marchal, J.6
-
86
-
-
0037222933
-
Oxidant-mediated mitochondrial injury in eosinophil apoptosis: Enhancement by glucocorticoids and inhibition by granulocyte-macrophage colony-stimulating factor
-
Gardai SJ, Hoontrakoon R, Goddard CD, Day BJ, Chang LY, Henson PM, et al. Oxidant-mediated mitochondrial injury in eosinophil apoptosis: enhancement by glucocorticoids and inhibition by granulocyte-macrophage colony-stimulating factor. J Immunol. 2003; 170:556-566.
-
(2003)
J Immunol
, vol.170
, pp. 556-566
-
-
Gardai, S.J.1
Hoontrakoon, R.2
Goddard, C.D.3
Day, B.J.4
Chang, L.Y.5
Henson, P.M.6
-
87
-
-
0034107113
-
Effect of IL-5, glucocorticoid, and Fas ligation on Bcl-2 homologue expression and caspase activation in circulating human eosinophils
-
Zangrilli J, Robertson N, Shetty A, Wu J, Hastie A, Fish JE, et al. Effect of IL-5, glucocorticoid, and Fas ligation on Bcl-2 homologue expression and caspase activation in circulating human eosinophils. Clin Exp Immunol. 2000; 120:12-21.
-
(2000)
Clin Exp Immunol
, vol.120
, pp. 12-21
-
-
Zangrilli, J.1
Robertson, N.2
Shetty, A.3
Wu, J.4
Hastie, A.5
Fish, J.E.6
-
88
-
-
0032014925
-
Human eosinophils express Bcl-2 family proteins: Modulation of Mcl-1 expression by IFN-gamma
-
Druilhe A, Arock M, Le Goff L, Pretolani M. Human eosinophils express Bcl-2 family proteins: modulation of Mcl-1 expression by IFN-gamma. Am J Respir Cell Mol Biol. 1998; 18:315-322.
-
(1998)
Am J Respir Cell Mol Biol
, vol.18
, pp. 315-322
-
-
Druilhe, A.1
Arock, M.2
Le Goff, L.3
Pretolani, M.4
-
89
-
-
0033110882
-
Expression of Bcl-2 and its homologues in human eosinophils. Modulation by interleukin-5
-
Dewson G, Walsh GM, Wardlaw AJ. Expression of Bcl-2 and its homologues in human eosinophils. Modulation by interleukin-5. Am J Respir Cell Mol Biol. 1999; 20:720-728.
-
(1999)
Am J Respir Cell Mol Biol
, vol.20
, pp. 720-728
-
-
Dewson, G.1
Walsh, G.M.2
Wardlaw, A.J.3
-
90
-
-
34447629367
-
The differential effect of dexamethasone on granulocyte apoptosis involves stabilization of Mcl-1L in neutrophils but not in eosinophils
-
Sivertson KL, Seeds MC, Long DL, Peachman KK, Bass DA. The differential effect of dexamethasone on granulocyte apoptosis involves stabilization of Mcl-1L in neutrophils but not in eosinophils. Cell Immunol. 2007; 246: 34-45.
-
(2007)
Cell Immunol
, vol.246
, pp. 34-45
-
-
Sivertson, K.L.1
Seeds, M.C.2
Long, D.L.3
Peachman, K.K.4
Bass, D.A.5
-
91
-
-
0033060178
-
Evaluation of apoptosis of eosinophils, macrophages, and T lymphocytes in mucosal biopsy specimens of patients with asthma and chronic bronchitis
-
Vignola AM, Chanez P, Chiappara G, Siena L, Merendino A, Reina C, et al. Evaluation of apoptosis of eosinophils, macrophages, and T lymphocytes in mucosal biopsy specimens of patients with asthma and chronic bronchitis. J Allergy Clin Immunol. 1999; 103:563-573.
-
(1999)
J Allergy Clin Immunol
, vol.103
, pp. 563-573
-
-
Vignola, A.M.1
Chanez, P.2
Chiappara, G.3
Siena, L.4
Merendino, A.5
Reina, C.6
-
92
-
-
0141956405
-
Endogenous nitric oxide downregulates the Bcl-2 expression of eosinophils through mitogen- activated protein kinase in bronchial asthma
-
Maa SH, Wang CH, Liu CY, Lin HC, Huang KH, Kuo HP. Endogenous nitric oxide downregulates the Bcl-2 expression of eosinophils through mitogen- activated protein kinase in bronchial asthma. J Allergy Clin Immunol. 2003; 112:761-767.
-
(2003)
J Allergy Clin Immunol
, vol.112
, pp. 761-767
-
-
Maa, S.H.1
Wang, C.H.2
Liu, C.Y.3
Lin, H.C.4
Huang, K.H.5
Kuo, H.P.6
-
93
-
-
9244256718
-
Expression of the apoptosis inhibitor bcl-2 in sputum eosinophils from children with acute asthma
-
El-Gamal Y, Heshmat N, Mahran M, El-Gabbas Z. Expression of the apoptosis inhibitor bcl-2 in sputum eosinophils from children with acute asthma. Clin Exp Allergy. 2004; 34:1701-1706.
-
(2004)
Clin Exp Allergy
, vol.34
, pp. 1701-1706
-
-
El-Gamal, Y.1
Heshmat, N.2
Mahran, M.3
El-Gabbas, Z.4
-
94
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
Kroemer G, Galluzzi L, Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol Rev. 2007; 87:99-163.
-
(2007)
Physiol Rev
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
95
-
-
80052627393
-
Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis
-
Rasola A, Bernardi P. Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis. Cell Calcium. 2011; 50:222-233.
-
(2011)
Cell Calcium
, vol.50
, pp. 222-233
-
-
Rasola, A.1
Bernardi, P.2
-
96
-
-
0035209820
-
Involvement of caspases and of mitochondria in Fas ligation-induced eosinophil apoptosis: Modulation by interleukin-5 and interferon-gamma
-
Letuve S, Druilhe A, Grandsaigne M, Aubier M, Pretolani M. Involvement of caspases and of mitochondria in Fas ligation-induced eosinophil apoptosis: modulation by interleukin-5 and interferon-gamma. J Leukoc Biol. 2001; 70:767-775.
-
(2001)
J Leukoc Biol
, vol.70
, pp. 767-775
-
-
Letuve, S.1
Druilhe, A.2
Grandsaigne, M.3
Aubier, M.4
Pretolani, M.5
-
97
-
-
0036010520
-
Critical role of mitochondria, but not caspases, during glucocorticosteroid-induced human eosinophil apoptosis
-
Letuve S, Druilhe A, Grandsaigne M, Aubier M, Pretolani M. Critical role of mitochondria, but not caspases, during glucocorticosteroid-induced human eosinophil apoptosis. Am J Respir Cell Mol Biol. 2002; 26:565-571.
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 565-571
-
-
Letuve, S.1
Druilhe, A.2
Grandsaigne, M.3
Aubier, M.4
Pretolani, M.5
-
98
-
-
69249100500
-
Human caspases: Activation, specificity, and regulation
-
Pop C, Salvesen GS. Human caspases: activation, specificity, and regulation. J Biol Chem. 2009; 284:21777-21781.
-
(2009)
J Biol Chem
, vol.284
, pp. 21777-21781
-
-
Pop, C.1
Salvesen, G.S.2
-
99
-
-
10644282148
-
The protein structures that shape caspase activity, specificity, activation and inhibition
-
Fuentes-Prior P, Salvesen GS. The protein structures that shape caspase activity, specificity, activation and inhibition. Biochem J. 2004; 384:201-232.
-
(2004)
Biochem J
, vol.384
, pp. 201-232
-
-
Fuentes-Prior, P.1
Salvesen, G.S.2
-
100
-
-
0033771527
-
Role of caspases in dexamethasone-induced apoptosis and activation of c-Jun NH2-terminal kinase and p38 mitogenactivated protein kinase in human eosinophils
-
Zhang JP, Wong CK, Lam CW. Role of caspases in dexamethasone-induced apoptosis and activation of c-Jun NH2-terminal kinase and p38 mitogenactivated protein kinase in human eosinophils. Clin Exp Immunol. 2000; 122: 20-27.
-
(2000)
Clin Exp Immunol
, vol.122
, pp. 20-27
-
-
Zhang, J.P.1
Wong, C.K.2
Lam, C.W.3
-
101
-
-
33745173850
-
Antieosinophilic activity of orazipone
-
Kankaanranta H, Ilmarinen P, Zhang X, Nissinen E, Moilanen E. Antieosinophilic activity of orazipone. Mol Pharmacol. 2006; 69:1861-1870.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 1861-1870
-
-
Kankaanranta, H.1
Ilmarinen, P.2
Zhang, X.3
Nissinen, E.4
Moilanen, E.5
-
102
-
-
77949720337
-
Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils
-
Kankaanranta H, Janka-Junttila M, Ilmarinen-Salo P, Ito K, Jalonen U, Ito M, et al. Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils. J Inflamm (Lond). 2010; 7:9.
-
(2010)
J Inflamm (Lond)
, vol.7
, pp. 9
-
-
Kankaanranta, H.1
Janka-Junttila, M.2
Ilmarinen-Salo, P.3
Ito, K.4
Jalonen, U.5
Ito, M.6
-
103
-
-
38049094235
-
Histamine reverses IL-5-afforded human eosinophil survival by inducing apoptosis: Pharmacological evidence for a novel mechanism of action of histamine
-
Hasala H, Giembycz MA, Janka-Junttila M, Moilanen E, Kankaanranta H. Histamine reverses IL-5-afforded human eosinophil survival by inducing apoptosis: pharmacological evidence for a novel mechanism of action of histamine. Pulm Pharmacol Ther. 2008; 21:222-233.
-
(2008)
Pulm Pharmacol Ther
, vol.21
, pp. 222-233
-
-
Hasala, H.1
Giembycz, M.A.2
Janka-Junttila, M.3
Moilanen, E.4
Kankaanranta, H.5
-
104
-
-
0035208625
-
Critical role for caspases 3 and 8 in neutrophil but not eosinophil apoptosis
-
Daigle I, Simon HU. Critical role for caspases 3 and 8 in neutrophil but not eosinophil apoptosis. Int Arch Allergy Immunol. 2001; 126:147-156.
-
(2001)
Int Arch Allergy Immunol
, vol.126
, pp. 147-156
-
-
Daigle, I.1
Simon, H.U.2
-
105
-
-
0033601746
-
Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases- 2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
-
Slee EA, Harte MT, Kluck RM, Wolf BB, Casiano CA, Newmeyer DD, et al. Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases- 2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J Cell Biol. 1999; 144:281-292.
-
(1999)
J Cell Biol
, vol.144
, pp. 281-292
-
-
Slee, E.A.1
Harte, M.T.2
Kluck, R.M.3
Wolf, B.B.4
Casiano, C.A.5
Newmeyer, D.D.6
-
106
-
-
0037336790
-
Overlap between death receptor and non-receptor-mediated mechanisms during apoptosis in human eosinophils
-
Niazi S, Robertson NM, Agrawal A, Hastie AT, Peters SP, Zangrilli J. Overlap between death receptor and non-receptor-mediated mechanisms during apoptosis in human eosinophils. Chest. 2003; 123:345S.
-
(2003)
Chest
, vol.345 S
, pp. 123
-
-
Niazi, S.1
Robertson, N.M.2
Agrawal, A.3
Hastie, A.T.4
Peters, S.P.5
Zangrilli, J.6
-
107
-
-
84877827899
-
Pin1-FADD interactions regulate Fas-mediated apoptosis in activated eosinophils
-
Oh J, Malter JS. Pin1-FADD interactions regulate Fas-mediated apoptosis in activated eosinophils. J Immunol. 2013; 190:4937-4945.
-
(2013)
J Immunol
, vol.190
, pp. 4937-4945
-
-
Oh, J.1
Malter, J.S.2
-
108
-
-
0030465544
-
Lamin proteolysis facilitates nuclear events during apoptosis
-
Rao L, Perez D, White E. Lamin proteolysis facilitates nuclear events during apoptosis. J Cell Biol. 1996; 135:1441-1455.
-
(1996)
J Cell Biol
, vol.135
, pp. 1441-1455
-
-
Rao, L.1
Perez, D.2
White, E.3
-
109
-
-
0033778360
-
Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis
-
Allsopp TE, McLuckie J, Kerr LE, Macleod M, Sharkey J, Kelly JS. Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis. Cell Death Differ. 2000; 7:984-993.
-
(2000)
Cell Death Differ
, vol.7
, pp. 984-993
-
-
Allsopp, T.E.1
McLuckie, J.2
Kerr, L.E.3
Macleod, M.4
Sharkey, J.5
Kelly, J.S.6
-
110
-
-
0037090614
-
Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation
-
Ruchaud S, Korfali N, Villa P, Kottke TJ, Dingwall C, Kaufmann SH, et al. Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation. EMBO J. 2002; 21:1967-1977.
-
(2002)
EMBO J
, vol.21
, pp. 1967-1977
-
-
Ruchaud, S.1
Korfali, N.2
Villa, P.3
Kottke, T.J.4
Dingwall, C.5
Kaufmann, S.H.6
-
111
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
-
Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia- Calvo M, et al. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J Biol Chem. 1997; 272:17907-17911.
-
(1997)
J Biol Chem
, vol.272
, pp. 17907-17911
-
-
Thornberry, N.A.1
Rano, T.A.2
Peterson, E.P.3
Rasper, D.M.4
Timkey, T.5
Garcia-calvo, M.6
-
112
-
-
79955458657
-
The calpain system and cancer
-
Storr SJ, Carragher NO, Frame MC, Parr T, Martin SG. The calpain system and cancer. Nat Rev Cancer. 2011; 11:364-374.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 364-374
-
-
Storr, S.J.1
Carragher, N.O.2
Frame, M.C.3
Parr, T.4
Martin, S.G.5
-
113
-
-
27844595293
-
Caspase and calpain function in cell death: Bridging the gap between apoptosis and necrosis
-
Harwood SM, Yaqoob MM, Allen DA. Caspase and calpain function in cell death: bridging the gap between apoptosis and necrosis. Ann Clin Biochem. 2005; 42:415-431.
-
(2005)
Ann Clin Biochem
, vol.42
, pp. 415-431
-
-
Harwood, S.M.1
Yaqoob, M.M.2
Allen, D.A.3
-
114
-
-
0036125004
-
Hydrogen peroxide reverses IL-5 afforded eosinophil survival and promotes constitutive human eosinophil apoptosis
-
Kankaanranta H, Giembycz MA, Barnes PJ, Haddad el-B, Saarelainen S, Zhang X, et al. Hydrogen peroxide reverses IL-5 afforded eosinophil survival and promotes constitutive human eosinophil apoptosis. Int Arch Allergy Immunol. 2002; 127:73-78.
-
(2002)
Int Arch Allergy Immunol
, vol.127
, pp. 73-78
-
-
Kankaanranta, H.1
Giembycz, M.A.2
Barnes, P.J.3
Haddad, E.-B.4
Saarelainen, S.5
Zhang, X.6
-
115
-
-
0033214683
-
Eosinophil apoptosis is mediated by stimulators of cellular oxidative metabolisms and inhibited by antioxidants: Involvement of a thiol-sensitive redox regulation in eosinophil cell death
-
Wedi B, Straede J, Wieland B, Kapp A. Eosinophil apoptosis is mediated by stimulators of cellular oxidative metabolisms and inhibited by antioxidants: involvement of a thiol-sensitive redox regulation in eosinophil cell death. Blood. 1999; 94:2365-2373.
-
(1999)
Blood
, vol.94
, pp. 2365-2373
-
-
Wedi, B.1
Straede, J.2
Wieland, B.3
Kapp, A.4
-
117
-
-
38449108808
-
Modulatory effects of N-acetyl-L-cysteine on human eosinophil apoptosis
-
Martinez-Losa M, Cortijo J, Juan G, Ramon M, Sanz MJ, Morcillo EJ. Modulatory effects of N-acetyl-L-cysteine on human eosinophil apoptosis. Eur Respir J. 2007; 30:436-442.
-
(2007)
Eur Respir J
, vol.30
, pp. 436-442
-
-
Martinez-Losa, M.1
Cortijo, J.2
Juan, G.3
Ramon, M.4
Sanz, M.J.5
Morcillo, E.J.6
-
119
-
-
84881187383
-
Mechanism of siglec-8-mediated cell death in IL-5-activated eosinophils: Role for reactive oxygen species- enhanced MEK/ERK activation
-
Kano G, Almanan M, Bochner BS, Zimmermann N. Mechanism of siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species- enhanced MEK/ERK activation. J Allergy Clin Immunol. 2013; 132:437-445.
-
(2013)
J Allergy Clin Immunol
, vol.132
, pp. 437-445
-
-
Kano, G.1
Almanan, M.2
Bochner, B.S.3
Zimmermann, N.4
-
120
-
-
34248597065
-
Differential regulation and properties of MAPKs
-
Raman M, Chen W, Cobb MH. Differential regulation and properties of MAPKs. Oncogene. 2007; 26:3100-3112.
-
(2007)
Oncogene
, vol.26
, pp. 3100-3112
-
-
Raman, M.1
Chen, W.2
Cobb, M.H.3
-
121
-
-
84856395989
-
Mitogen-activated protein kinase phosphatase (MKP)-1 in immunology, physiology, and disease
-
Wancket LM, Frazier WJ, Liu Y. Mitogen-activated protein kinase phosphatase (MKP)-1 in immunology, physiology, and disease. Life Sci. 2012; 90:237-248.
-
(2012)
Life Sci
, vol.90
, pp. 237-248
-
-
Wancket, L.M.1
Frazier, W.J.2
Liu, Y.3
-
122
-
-
0033796587
-
A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs
-
Eichhorst ST, Muller M, Li-Weber M, Schulze-Bergkamen H, Angel P, Krammer PH. A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs. Mol Cell Biol. 2000; 20:7826-7837.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7826-7837
-
-
Eichhorst, S.T.1
Muller, M.2
Li-Weber, M.3
Schulze-Bergkamen, H.4
Angel, P.5
Krammer, P.H.6
-
123
-
-
0037046509
-
Evidence that the human death receptor 4 is regulated by activator protein 1
-
Guan B, Yue P, Lotan R, Sun SY. Evidence that the human death receptor 4 is regulated by activator protein 1. Oncogene. 2002; 21:3121-3129.
-
(2002)
Oncogene
, vol.21
, pp. 3121-3129
-
-
Guan, B.1
Yue, P.2
Lotan, R.3
Sun, S.Y.4
-
124
-
-
0038677013
-
C-Jun N-terminal kinase (JNK)-mediated modulation of brain mitochondria function: New target proteins for JNK signalling in mitochondrion-dependent apoptosis
-
Schroeter H, Boyd CS, Ahmed R, Spencer JP, Duncan RF, Rice-Evans C, et al. c-Jun N-terminal kinase (JNK)-mediated modulation of brain mitochondria function: new target proteins for JNK signalling in mitochondrion-dependent apoptosis. Biochem J. 2003; 372:359-369.
-
(2003)
Biochem J
, vol.372
, pp. 359-369
-
-
Schroeter, H.1
Boyd, C.S.2
Ahmed, R.3
Spencer, J.P.4
Duncan, R.F.5
Rice-Evans, C.6
-
125
-
-
33845653234
-
Uses for JNK: The many and varied substrates of the c-Jun N-terminal kinases
-
Bogoyevitch MA, Kobe B. Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases. Microbiol Mol Biol Rev. 2006; 70:1061-1095.
-
(2006)
Microbiol Mol Biol Rev
, vol.70
, pp. 1061-1095
-
-
Bogoyevitch, M.A.1
Kobe, B.2
-
126
-
-
46649084880
-
Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury
-
Hanawa N, Shinohara M, Saberi B, Gaarde WA, Han D, Kaplowitz N. Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury. J Biol Chem. 2008; 283:13565-13577.
-
(2008)
J Biol Chem
, vol.283
, pp. 13565-13577
-
-
Hanawa, N.1
Shinohara, M.2
Saberi, B.3
Gaarde, W.A.4
Han, D.5
Kaplowitz, N.6
-
127
-
-
62149094246
-
Chronic high- dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway
-
Lin X, Wang YJ, Li Q, Hou YY, Hong MH, Cao YL, et al. Chronic high- dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway. FEBS J. 2009; 276:2022-2036.
-
(2009)
FEBS J
, vol.276
, pp. 2022-2036
-
-
Lin, X.1
Wang, Y.J.2
Li, Q.3
Hou, Y.Y.4
Hong, M.H.5
Cao, Y.L.6
-
128
-
-
33745487368
-
Cell apoptosis: Requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3
-
Lu C, Zhu F, Cho YY, Tang F, Zykova T, Ma WY, et al. Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3. Mol Cell. 2006; 23:121-132.
-
(2006)
Mol Cell
, vol.23
, pp. 121-132
-
-
Lu, C.1
Zhu, F.2
Cho, Y.Y.3
Tang, F.4
Zykova, T.5
Ma, W.Y.6
-
129
-
-
34447507590
-
Terminal kinase mediates constitutive human eosinophil apoptosis
-
Hasala H, Zhang X, Saarelainen S, Moilanen E, Kankaanranta H. c-Jun N- terminal kinase mediates constitutive human eosinophil apoptosis. Pulm Pharmacol Ther. 2007; 20:580-587.
-
(2007)
Pulm Pharmacol Ther
, vol.20
, pp. 580-587
-
-
Hasala, H.1
Zhang, X.2
Saarelainen, S.3
Moilanen, E.4
Kankaanranta, H.5
C-Jun N-6
-
130
-
-
0029934289
-
JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells
-
Wilson DJ, Fortner KA, Lynch DH, Mattingly RR, Macara IG, Posada JA, et al. JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells. Eur J Immunol. 1996; 26:989-994.
-
(1996)
Eur J Immunol
, vol.26
, pp. 989-994
-
-
Wilson, D.J.1
Fortner, K.A.2
Lynch, D.H.3
Mattingly, R.R.4
Macara, I.G.5
Posada, J.A.6
-
131
-
-
0029821787
-
CD95 (APO-1/Fas) induces activation of SAP kinases downstream of ICE-like proteases
-
Cahill MA, Peter ME, Kischkel FC, Chinnaiyan AM, Dixit VM, Krammer PH, et al. CD95 (APO-1/Fas) induces activation of SAP kinases downstream of ICE-like proteases. Oncogene. 1996; 13:2087-2096.
-
(1996)
Oncogene
, vol.13
, pp. 2087-2096
-
-
Cahill, M.A.1
Peter, M.E.2
Kischkel, F.C.3
Chinnaiyan, A.M.4
Dixit, V.M.5
Krammer, P.H.6
-
132
-
-
0032472837
-
Disruption of Fas receptor signaling by nitric oxide in eosinophils
-
Hebestreit H, Dibbert B, Balatti I, Braun D, Schapowal A, Blaser K, et al. Disruption of Fas receptor signaling by nitric oxide in eosinophils. J Exp Med. 1998; 187:415-425.
-
(1998)
J Exp Med
, vol.187
, pp. 415-425
-
-
Hebestreit, H.1
Dibbert, B.2
Balatti, I.3
Braun, D.4
Schapowal, A.5
Blaser, K.6
-
133
-
-
84868576347
-
Germinal center kinases in immune regulation
-
Yin H, Shi Z, Jiao S, Chen C, Wang W, Greene MI, et al. Germinal center kinases in immune regulation. Cell Mol Immunol. 2012; 9:439-445.
-
(2012)
Cell Mol Immunol
, vol.9
, pp. 439-445
-
-
Yin, H.1
Shi, Z.2
Jiao, S.3
Chen, C.4
Wang, W.5
Greene, M.I.6
-
134
-
-
34547161916
-
Activation of the c-Jun N-terminal kinase pathway by MST1 is essential and sufficient for the induction of chromatin condensation during apoptosis
-
Ura S, Nishina H, Gotoh Y, Katada T. Activation of the c-Jun N-terminal kinase pathway by MST1 is essential and sufficient for the induction of chromatin condensation during apoptosis. Mol Cell Biol. 2007; 27:5514-5522.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 5514-5522
-
-
Ura, S.1
Nishina, H.2
Gotoh, Y.3
Katada, T.4
-
135
-
-
0036565878
-
Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosis
-
De Souza PM, Kankaanranta H, Michael A, Barnes PJ, Giembycz MA, Lindsay MA. Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosis. Blood. 2002; 99:3432-3438.
-
(2002)
Blood
, vol.99
, pp. 3432-3438
-
-
de Souza, P.M.1
Kankaanranta, H.2
Michael, A.3
Barnes, P.J.4
Giembycz, M.A.5
Lindsay, M.A.6
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