Disruption of Fas receptor signaling by nitric oxide in eosinophils

Journal of Experimental Medicine

Volumn 187, Issue 3, 1998, Pages 415-425

  Hebestreit, Holger ^a   Dibbert, Birgit ^a   Balatti, Ivo ^a   Braun, Doris ^b   Schapowal, Andreas ^b   Blaser, Kurt ^a   Simon, Hans Uwe ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b Clinic for Dermatology and Allergy   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; INTERLEUKIN 1; LAMIN B; NITRIC OXIDE; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR;

ALLERGIC PNEUMONITIS; ANIMAL CELL; APOPTOSIS; ARTICLE; ASTHMA; CELL DEATH; CELL SURVIVAL; ENZYME ACTIVITY; EOSINOPHILIA; IMMUNE RESPONSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

APOPTOSIS; CELL SURVIVAL; COCULTURE TECHNIQUES; EOSINOPHILS; FAS LIGAND PROTEIN; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTOCYTOCHEMISTRY; HUMANS; IMMUNOBLOTTING; MEMBRANE GLYCOPROTEINS; NASAL POLYPS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RNA; SECOND MESSENGER SYSTEMS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0032472837     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.3.415     Document Type: Article

References (59)

1. Simon, H.-U., and K. Blaser. 1995. Inhibition of programmed eosinophil death: a key pathogenic event for eosinophilia? Immunol. Today. 16:53-55.
2. Simon, H.-U., S. Yousefi, C. Schranz, A. Schapowal, C. Bachert, and K. Blaser. 1997. Direct demonstration of delayed eosinophil apoptosis as a mechanism causing tissue eosinophilia. J. Immunol. 158:3902-3908.
3. Rothenberg, M.E., R.L. Stevens, D.S. Silberstein, R. Soberman, K.F. Austen, and W.F. Owen. 1989. IL-5 promotes long-term culture and enhances functional properties of human eosinophils. J. Immunol. 143:2311-2316.
4. Yamaguchi, Y., T. Suda, S. Ohta, K. Tominaga, Y. Miura, and T. Kasahara. 1991. Analysis of the survival of mature human eosinophils: interleukin-5 prevents apoptosis in mature human eosinophils. Blood. 78:2542-2547.
5. Walker, C., J.C. Virchow, P.L.B. Bruijnzeel, and K. Blaser. 1991. T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma. J. Immunol. 146: 1829-1835.
6. Stern, M., L. Meagher, J. Savill, and C. Haslett. 1992. Apoptosis in human eosinophils. Programmed cell death in the eosinophil leads to phagocytosis by macrophages and is modulated by IL-5. J. Immunol. 148:3543-3549.
7. Yousefi, S., D.R. Green, K. Blaser, and H.-U. Simon. 1994. Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils. Proc. Natl. Acad. Sci. USA. 91:10868-10872.
8. Yousefi, S., D.C. Hoessli, K. Blaser, G.B. Mills, and H.-U. Simon. 1996. Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils. J. Exp. Med. 183:1407-1414.
9. - T cells associated with abnormal Fas expression and hypereosinophilia. J. Exp. Med. 183:1071-1082.
10. Matsumoto, K., R.P. Schleimer, H. Saito, Y. Iikura, and B.S. Bochner. 1995. Induction of apoptosis in human eosinophils by anti-Fas antibody treatment in vitro. Blood. 86:1437-1443.
11. Tsuyuki, S., C. Bertrand, F. Erard, A. Trifilieff, J. Tsuyuki, M. Wesp, G.P. Anderson, and A.J. Coyle. 1995. Activation of the Fas receptor on lung eosinophils leads to apoptosis and the resolution of eosinophilic inflammation of the airways. J. Clin. Invest. 96:2924-2931.
12. Druilhe, A., Z. Cai, S. Hailé, S. Chonaib, and M. Petrolani. 1996. Fas-mediated apoptosis in cultured human eosinophils. Blood. 87:2822-2830.
13. Hebestreit, H., S. Yousefi, I. Balatti, M. Weber, R. Crameri, D. Simon, K. Hartung, A. Schapowal, K. Blaser, and H.-U. Simon. 1996. Expression and function of the Fas receptor on human blood and tissue eosinophils. Eur. J. Immunol. 26: 1775-1780.
14. Alving, K.E., E. Weitzberg, and J.M. Lundberg. 1993. Increased amount of nitric oxide in exhaled air of asthmatics. Eur. Respir. J. 6:1268-1370.
15. Kharitonov, S.A., K. Rajakulasingam, B. O'Connor, S.R. Durham, and P.J. Barnes. 1997. Nasal nitric oxide is increased in patients with asthma and allergic rhinitis and may be modulated by nasal glucocorticoids. J. Allergy Clin. Immunol. 99:58-64.
16. Palmer, R.M.J., D.S. Ashton, and S. Moncada. 1988. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature. 333:664-666.
17. Hamid, Q., D.R. Springall, V. Riveros-Moreno, P. Chanez, P. Howarth, A. Redington, J. Bousquet, P. Godard, S. Holgate, and J.M. Polak. 1993. Induction of nitric oxide synthase in asthma. Lancet. 342:1510-1513.
18. del Pozo, V., E. de Arruda-Chaves, B. de Andrés, B. Cardaba, A. Lopez-Farré, S. Gallardo, I. Cortegano, L. Vidarte, A. Jurado, J. Sastre, et al. 1997. Eosinophils transcribe and translate messenger RNA for inducible nitric oxide synthase. J. Immunol. 158:859-864.
19. Abrahamsohn, I.S., and R.L. Coffman. 1995. Cytokine and nitric oxide regulation of the immunosuppression in trypanosoma cruzi infection. J. Immunol. 155:3955-3963.
20. Sternberg, J.M., and N.A. Mabbott. 1996. Nitric oxide-mediated suppression of T cell responses during trypanosoma brucei infection: soluble trypanosome products and interferon-γ are synergistic inducers of nitric oxide synthase. Eur. J. Immunol. 26:539-543.
21. Taylor-Robinson, A.W., F.Y. Liew, A. Severn, D. Xu, S.J. McSorley, P. Garside, J. Padron, and R.S. Phillips. 1994. Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells. Eur. J. Immunol. 24:980-984.
22. Barnes, P.J., and F.Y. Liew. 1995. Nitric oxide and asthmatic inflammation. Immunol. Today. 16:128-130.
23. Bohlinger, I., M. Leist, J. Barsig, S. Uhlig, G. Tiegs, and A. Wendel. 1995. Interleukin-1 and nitric oxide protect against tumor necrosis factor α-induced liver injury through distinct pathways. Hepatology. 22:1829-1837.
24. Boldin, M.P., T.M. Goncharov, Y.V. Goltsev, and D. Wallach. 1996. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1-and TNF receptor-induced cell death. Cell. 85:803-815.
25. Yousefi, S., S. Hemmann, M. Weber, C. Hölzer, K. Hartung, and H.-U. Simon. 1995. IL-8 is expressed by human peripheral blood eosinophils. Evidence for increased secretion in asthma. J. Immunol. 154:5481-5490.
26. Simon, H.-U., P.W. Tsao, K.A. Siminovitch, G.B. Mills, and K. Blaser. 1994. Functional platelet-activating factor receptors are expressed by monocytes and granulocytes but not by resting or activated T and B lymphocytes from normal individuals or patients with asthma. J. Immunol. 153:364-377.
27. Moro, M.A., R.J. Russel, S. Cellek, I. Lizasoain, Y. Su, V.M. Darley-Usmar, M.W. Radomski, and S. Moncada. 1996. cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase. Proc. Natl. Acad. Sci. USA. 93:1480-1485.
28. Martin, S.J., C.P.M. Reutelingsperger, A.J. McGahon, J.A. Rader, R.C.A.A. van Schie, D.M. LaFace, and D.R. Green. 1995. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med. 182:1545-1556.
29. Cifone, M.G., R. De Maria, F. Roncaioli, M.R. Rippo, M. Azuma, L.L. Lanier, A. Santoni, and R. Testi. 1993. Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J. Exp. Med. 177:1547-1552.
30. Wilson, D.J., K.A. Fortner, D.H. Lynch, R.R. Mattingly, I.G. Macara, J.A. Posada, and R.C. Budd. 1996. JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells. Eur. J. Immunol. 26:989-994.
31. Pacifici, R.E., and K.J.A. Davies. 1990. Protein degradation as an index of oxidative stress. Methods Enzymol. 186:485-502.
32. Brown, P.D., A.T. Levy, I.M. Margulies, L.A. Liotta, and W.G. Stetler-Stevenson. 1990. Independent expression and cellular processing of Mr 72.000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines. Cancer Res. 50:6184-6191.
33. Nicholls, P. 1964. The reactions of azide with catalase and their significance. Biochem. J. 90:331-343.
34. Ignarro, L.J., H. Lippton, J.C. Edwards, W.H. Baricos, A.L. Hyman, P.J. Kadowitz, and C.A. Gruetter. 1981. Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates. J. Pharmacol. Exp. Ther. 218:739-749.
35. Moncada, S., and A. Higgs. 1993. The L-arginine-nitric oxide pathway. N. Engl. J. Med. 329:2002-2012.
36. Thusu, K.G., F.C. Morin, J.A. Russell, and R.H. Steinhorn. 1995. The cGMP phosphodiesterase inhibitor Zaprinast enhances the effect of nitric oxid. Am J. Respir. Crit. Care Med. 152:1605-1610.
37. Gulbins, E., R. Bissonnette, A. Mahboubi, S. Martin, W. Nishioka, T. Brunner, G. Baier, G. Baier-Bitterlich, C. Byrd, F. Lang, et al. 1995. Fas-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway. Immunity. 2: 341-351.
38. Tepper, C.G., S. Jayadev, B. Liu, A. Bielawska, R. Wolff, S. Yonehara, Y.A. Hannun, and M.F. Seldin. 1995. Role of ceramide as an endogenous mediator of Fas-induced cytotoxicity. Proc. Natl. Acad. Sci. USA. 92:8443-8447.
39. Cahill, M.A., M.E. Peter, F.C. Kischkel, A.M. Chinnaiyan, V.M. Dixit, P.H. Krammer, and A. Nordheim. 1996. CD95 (APO-1/Fas) induces activation of SAP kinases downstream of ICE-like proteases. Oncogene. 13:2087-2096.
40. Chauhan, D., S. Kharbanda, A. Ogata, M. Urashima, G. Teoh, M. Robertson, D.W. Kufe, and K.C. Anderson. 1997. Interleukin-6 inhibits Fas-induced apoptosis and stress-activated protein kinase activation in multiple myeloma cells. Blood. 89:227-234.
41. Dérijard, B., M. Hibi, I. Wu, T. Barrett, B. Su, T. Deng, M. Karin, and R.J. Davis. 1994. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-jun activation domain. Cell. 76:1025-1037.
42. Liu, Z.-G., R. Baskaran, E.T. Lea-Chou, L.D. Wood, Y. Chen, M. Karin, and J.Y.J. Wang. 1996. Three distinct signalling responses by murine fibroblasts to genotoxic stress. Nature. 384:273-276.
43. Martin, S.J., and D.R. Green. 1995. Protease acitvation during apoptosis: Death by a thousand cuts. Cell. 82:349-352.
44. Oberhammer, F.A., K. Hochegger, G. Froschl, R. Tiefenbacher, and M. Pavelka. 1994. Chromatin condensation during apoptosis is accompanied by degradation of lamin A + B, without enhanced activation of cdc2 kinase. J. Cell Biol. 126: 827-837.
45. Lazebnik, Y., A. Takahashi, R.D. Moir, R.D. Goldman, G.G. Poirier, S.H. Kaufmann, and W.G. Earnshaw. 1995. Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution. Proc. Natl. Acad. Sci. USA. 92:9042-9046.
46. Bousquet, J., P. Chanez, J.Y. Lacoste, G. Barnéon, N. Ghavanian, I. Enander, P. Venge, S. Ahlstedt, J. Simony-Lafontaine, P. Godard, and F.-B. Michel. 1990. Eosinophilic inflammation in asthma. N. Engl. J. Med. 323:1033-1039.
47. Drazen, J.M., J.P. Arm, and K.F. Austen. 1996. Sorting out the cytokines of asthma. J. Exp. Med. 183:1-5.
48. Nagata, S. 1997. Apoptosis by death factor. Cell. 88:355-365.
49. Mapara, M.Y., R. Bargou, C. Zugck, H. Dohner, F. Ustaoglu, R.R. Jonker, P.H. Krammer, and B. Dörken. 1993. APO-1 mediated apoptosis or proliferation in human chronic B lymphocytic leukemia: correlation with bcl-2 oncogen expression. Eur. J. Immunol. 23:702-708.
50. Owen-Schaub, L.B., R. Radinski, E. Kruzel, K. Berry, and S. Yonehara. 1994. Anti-Fas on non-hematopoietic tumors: levels of Fas/APO-1 and bcl-2 are not predictive of biological responsiveness. Cancer Res. 54:1580-1586. 158:1912-1918.
51. Kischkel, F.C., S. Hellbardt, I. Behrmann, M. Germer, M. Pawlita, P.H. Krammer, and M.E. Peter. 1995. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO (Eur. Mol. Biol. Organ.) J. 14:5579-5588.
52. Muzio, M., A.M. Chinnaiyan, F.C. Kischkel, K. O'Rourke, A. Shevchenko, J. Ni, C. Scaffidi, J.D. Bretz, M. Zhang, R. Gentz, et al. 1996. FLICE, a novel FADD-homologous ICE/ CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell. 85:817-827.
53. Eischen, C.M., C.J. Dick, and P.J. Leibson. 1994. Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis. J. Immunol. 153:1947-1954.
54. Haimovitz-Friedman, A., C. Kan, D. Ehleiter, R. Persaud, M. McLoghlin, Z. Fuks, and R.N. Kolesnick. 1994. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J. Exp. Med. 180:525-535.
55. McGahon, A.J., W.K. Nishioka, S.J. Martin, A. Mahboubi, T.G. Cotter, and D.R. Green. 1995. Regulation of the Fas apoptotic cell death pathway by Abl. J. Biol. Chem. 270: 22625-22631.
56. Pronk, G.J., K. Ramer, P. Amiri, and L.T. Williams. 1996. Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER. Science. 271: 808-810.
57. Zhana, Y., B. Yao, S. Delikat, S. Bayoumy, X.-H. Lin, S. Basu, M. McGinley, P.-Y. Chan-Hui, H. Lichenstein, and R. Kolesnick. 1997. Kinase suppressor of Ras is ceramide-activated protein kinase. Cell. 89:63-72.
58. Enari, M., R.V. Talanian, W.W. Wong, and S. Nagata. 1996. Sequential activation ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature. 380:723-726.
59. Huang, S., Y. Jiang, Z. Li, E. Nishida, P. Mathias, S. Lin, R.J. Ulevitch, G.R. Nemerow, and J. Han. 1997. Apoptosis signaling pathway in T cells is composed of ICE/Ced-3 family proteases and MAP kinase kinase 6b. Immunity. 6:739-749.