Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation

EMBO Journal

Volumn 21, Issue 8, 2002, Pages 1967-1977

  Ruchaud, Sandrine ^a   Korfali, Nadia ^a   Villa, Pascal ^a   Kottke, Timothy J ^b   Dingwall, Colin ^c   Kaufmann, Scott H ^d   Earnshaw, William C ^e  

^a DIVISION OF REPRODUCTIVE BIOLOGY   (United States)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c RESEARCH AND DEVELOPMENT   (Australia)

^d College of Chemistry and Molecular Engineering ^*  (China)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Apoptosis; Caspase 6; Chromatin condensation; DT40; Lamins

Indexed keywords

CASPASE 6; CASPASE INHIBITOR; CELL EXTRACT; DNA; LAMIN A; LAMIN C;

ALLELE; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CLONE; CELL FREE SYSTEM; CELL LINE; CHICKEN; CHROMATIN CONDENSATION; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE DISRUPTION; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; CASPASE 6; CASPASES; CELL NUCLEUS; CHICKENS; CHROMATIN; GENE TARGETING; HELA CELLS; HUMANS; JURKAT CELLS; LAMIN TYPE A; LAMINS; NUCLEAR PROTEINS; PHENOTYPE; TUMOR CELLS, CULTURED;

ANIMALIA; GALLUS GALLUS;

EID: 0037090614     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/21.8.1967     Document Type: Article

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