Apoptosis, proliferation, and expression of Bcl-2, Fas, and Fas ligand in bronchial biopsies from asthmatics

American Journal of Respiratory Cell and Molecular Biology

Volumn 19, Issue 5, 1998, Pages 747-757

  Druilhe, Anne ^b   Wallaert, Benoît ^b   Tsicopoulos, Anne ^b   Lapa E Silva, José Roberto ^b   Tillie Leblond, Isabelle ^b   Tonnel, André Bernard ^b   Pretolani, Marina ^a  

^a INSTITUT PASTEUR   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BRONCHUS;

CYCLINE; FAS LIGAND; FASLG PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; PROTEIN BCL 2; STEROID;

ADULT; APOPTOSIS; ARTICLE; ASTHMA; BIOPSY; BRONCHUS; CELL DIVISION; CELL NUCLEUS; CYTOLOGY; EOSINOPHIL; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; NICK END LABELING;

ADULT; ANTIGENS, CD; APOPTOSIS; ASTHMA; BIOPSY; BRONCHI; CELL DIVISION; CELL NUCLEUS; EOSINOPHILS; FAS LIGAND PROTEIN; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MEMBRANE GLYCOPROTEINS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTO-ONCOGENE PROTEINS C-BCL-2; STEROIDS;

EID: 0032209561     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.19.5.3166     Document Type: Article

References (46)

1. Haanen, C., and I. Vermes. 1995. Apoptosis and inflammation. Med. Inflamm. 4:5-15.
2. Reed, J. 1994. Bel-2 and the regulation of programmed cell death. J. Cell Biol. 124:1-6.
3. Cosman, D. 1994. A family of ligands for the TNF receptor superfamily. Stem Cells 12:440-455.
4. Solary, E., L. Dubrez, and B. Eymin. 1996. The role of apoptosis in the pathogenesis and treatment of diseases. Eur. Respir. J. 9:1293-1305.
5. Holgate, S. T. 1993. Asthma: past, present and future. Eur. Respir. J. 6:1507-1520.
6. Robinson, D. S., O. Hamid, S. Ying, A. Tsicopoulos, J. Barkans, A. M. Bentley, C. Corrigan, S. R. Durham, and A. B. Kay. 1992. Predominant Th2-like bronchoalveolar T-lymphocyte population in atopic asthma. N. Engl. J. Med. 326:298-304.
7. Kroegel, C., J.-C. Virchow, W. Luttmann, C. Walker, and J. A. Warner. 1994. Pulmonary immune cells in health and disease: the eosinophil leukocyte (Part I). Eur. Respir. J. 7:519-543.
8. Wardlaw, A. J., S. Dunnette, G. J. Gleich, J. V. Collins, and A. B. Kay. 1988. Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Am. Rev. Respir. Dis. 137:62-69.
9. Beasley, R., W. R. Roche, J. A. Roberts, and S. T. Holgate. 1989. Cellular events in the bronchi in mild asthma and after bronchial provocation. Am. Rev. Respir. Dis. 139:806-817.
10. Rennard, S. I. 1996. Repair mechanisms in asthma. J. Allergy Clin. Immunol. 98:S278-S286.
11. Reed, C. 1991. Aerosol steroids as the primary treatment of mild asthma. N. Engl. J. Med. 325:425-126.
12. Bentley, A. M., Q. Hamid, D. S. Robinson, E. Schotman, Q. Meng, B. Assoufi, A. B. Kay, and S. R. Durham. 1996. Prednisolone treatment in asthma: reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa. Am. J. Respir. Crit. Care Med. 153:551-556.
13. Druilhe, A., Z. Cai, S. Hailé, S. Chouaib, and M. Pretolani. 1996. Fas-mediated apoptosis in cultured human eosinophils. Blood 87:2822-2830.
14. Meagher, L. C., J. M. Cousin, J. R. Seckl, and C. Haslett. 1996. Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes. J. Immunol. 156:4422-4428.
15. Brunetti, M., N. Martelli, A. Colasante, M. Piantelli, P. Musiani, and F. B. Aiello. 1995. Spontaneous and glucocorticoid-induced apoptosis in human mature T lymphocytes. Blood 86:4199-4205.
16. 1992. International consensus report on diagnosis and management of asthma. Eur. Respir. J. 5:601-641.
17. Aas, K. 1981. Heterogeneity of bronchial asthma: sub-populations or different stages of the disease. Allergy 36:3-14.
18. Summary and recommendations of a workshop on the investigative use of fiberoptic bronchoscopy and bronchoalveolar lavage in asthmatics. 1985. Am. Rev. Respir. Dis. 132:180-182.
19. Jones, D. G. 1993. The eosinophil. J. Comp. Pathol. 108:317-335.
20. Gavrieli, Y., Y. Sherman, and S. A. Sasson. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:493-501.
21. Wooley, K. L., E. Adelroth, M. J. Wooley, I. Ramis, J. S. Abrams, M. Jordana, and P. O'Byrne. 1996. Interleukin-3 in bronchial biopsies from non-asthmatics and patients with mild and allergen-induced asthma. Am. J. Respir. Crit. Care Med. 153:350-355.
22. Sont, J. K., J. H. J. M. van Krieken, H. C. J. van Klink, A. C. Roldaan, C. R. Apap, L. N. A. Willems, and P. J. Sterk. 1997. Enhanced expression of neutral endopeptidase (NEP) in airway epithelium in biopsies from steroid-versus nonsteroid-treated patients with atopic asthma. Am. J. Respir. Cell Mol. Biol. 16:549-556.
23. Moqbel, R., J. Barkans, B. L. Bradley, S. R. Durham, and A. B. Kay. 1992. Application of monoclonal antibodies against major basic protein (BMK-13) and eosinophil cationic protein (EG1 and EG2) for quantifying eosinophils in bronchial biopsies from atopic asthma. Clin. Exp. Allergy 22:265-273.
24. Bousquet, J., P. Chanez, J. Y. Lacoste, G. Barnéon, N. Ghavanian, I. Enander, P. Venge, S. Ahlstedt, J. Simony-Lafontaine, P. Godard, and F.-B. Michel. 1990. Eosinophilic inflammation in asthma. N. Engl. J. Med. 323: 1033-1039.
25. Bentley, A. M., G. Menz, C. H. R. Storz, D. S. Robinson, B. Bradley, P. K. Jeffery, S. R. Durham, and A. B. Kay. 1992. Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Am. Rev. Respir. Dis. 146:500-506.
26. Hamid, Q., M. Azzawi, S. Ying, R. Moqbel, A. J. Wardlaw, C. J. Corrigan, B. Bradley, S. R. Durham, J. V. Collins, P. K. Jeffery, D. J. Quint, and A. B. Kay. 1991. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J Clin. Invest. 87:1541-1546.
27. Wooley, K. L., E. Adelroth, M. J. Wooley, R. Ellis, M. Jordana, and P. M. O'Byrne. 1994. Granulocyte-macrophage colony-stimulating factor, eosinophils and eosinophil cationic protein in subjects with and without mild, stable, atopic asthma. Eur. Respir. J. 7:1576-1584.
28. Wooley, K. L., P. G. Gibson, K. Carty, A. J. Wilson, S. H. Swaddell, and M. J. Wooley. 1996. Eosinophil apoptosis and the resolution of airway inflammation in asthma. Am. J. Respir. Crit. Care Med. 154:237-243.
29. Rolfe, F. G., J. M. Hughes, C. L. Armour, and W. A. Sewell. 1992. Inhibition of interleukin-5 gene expression by dexamethasone. Immunology 77: 494-499.
30. Ohta, K., K. Iwai, Y. Kasahara, N. Taniguchi, S. Krajewski, J. C. Reed, and T. Miyawaki. 1995. Immunoblot analysis of cellular expression of Bcl-2 family proteins, Bcl-2, Bax, Bcl-x and Mcl-1, in human peripheral blood and lymphoid tissues. Int. Immunol. 7:1817-1825.
31. Druilhe, A., M. Arock, L. Le Goff, and M. Pretolani. 1998. Human eosinophils express Bcl-2 family proteins: modulation of Mcl-1 expression by IFN-γ. Am. J. Respir. Cell Mol. Biol. 18:315-322.
32. Crispe, N. 1995. Fatal interactions: Fas-induced apoptosis of mature T cells. Immunity 1:347-349.
33. Matsumoto, K., R. P. Schleimer, H. Saito, Y. Iikura, and B. S. Bochner. 1995. Induction of apoptosis in human eosinophils by anti-Fas antibody treatment in vitro. Blood 86:1437-1443.
34. Hebestreit, H., S. Yousefi, I. Balatti, M. Weber, R. Crameri, D. Simon, K. Hartung, A. Schapowal, K. Blaser, and H.-U. Simon. 1996. Expression and function of the Fas receptor on human blood and tissue eosinophils. Eur. J. Immunol. 26:1775-1780.
35. Liles, C., P. A. Kiener, J. A. Ledbetter, A. Aruffo, and S. J. Klebanoff. 1996. Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils. J. Exp. Med. 184:429-440.
36. Freiberg, R. A., D. M. Spencer, K. A. Choate, H. J. Duh, S. L. Schreiber, G. R. Crabtree, and P. A. Khavari. 1997. Fas signal transduction triggers either proliferation or apoptosis in human fibroblasts. J. Invest. Dermatol. 108:215-219.
37. Wang, E. 1995. Senescent human fibroblasts resist programmed cell death, and failure to suppress Bcl-2 is involved. Cancer Res. 55:2284-2292.
38. Mandik, L., K. A. Nguyen, and J. Erikson. 1995. Fas receptor expression on B-lineage cells. Eur. J. Immunol. 25:3148-3154.
39. Hahne, M., T. Renno, M. Schroeter, M. Irmler, L. French, T. Bornand, H. R. MacDonald, and J. Tschopp. 1996. Activated B-cells express functional Fas ligand. Eur. J. Immunol. 26:721-724.
40. + lymphocytes delete activated macrophages through the Fas/APO-1 antigen pathway. Proc. Natl. Acad. Sci. USA 92: 11225-11229.
41. Bullock, E. D., and E. M. Johnson. 1996. Nerve growth factor induces the expression of certain cytokine genes and Bcl-2 in mast cells: potential role in survival promotion. J. Biol. Chem. 271:27500-27508.
42. Hockenberry, D. M., M. Zutter, W. Hickey, M. Nahm, and S. J. Korsmeyer. 1991. Bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc. Natl. Acad. Sci. USA 88:6961-6965.
43. Lu, Q. L., P. Abel, C. S. Foster, and E. N. Lalani. 1996. Bcl-2: a role in epithelial differentiation and oncogenesis. Hum. Pathol. 27:102-110.
44. Hagimoto, N., K. Kuwano, Y. Nomoto, R. Kunitake, and N. Hara. 1996. Apoptosis and expression of Fas/FasL mRNA in bleomycin-induced pulmonary fibrosis in mice. Am. J. Respir. Cell Mol. Biol. 16:91-101.
45. French, L. E., M. Hahne, I. Viard, G. Radlgruber, R. Zanone, K. Becker, C. Müller, and J. Tschopp. 1996. Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover. J. Cell Biol. 133:335-343.
46. Dayan, C. M., K. A. Elsegood, and R. Maile. 1997. FasL expression on epithelial cells: the Bottazzo-Feldmann hypothesis revisited. Immunol. Today 18:203.