-
1
-
-
0030444654
-
Eosinophil apoptosis caused by theophylline, glucocorticoids and macrolides after stimulation with IL-5
-
Adachi T, Motojima S, Hirata A, Fukuda T, Kihara N, Kosaku A, Ohtake H, and Makino S (1996) Eosinophil apoptosis caused by theophylline, glucocorticoids and macrolides after stimulation with IL-5. J Allergy Clin Immunol 98:S207-S215.
-
(1996)
J Allergy Clin Immunol
, vol.98
-
-
Adachi, T.1
Motojima, S.2
Hirata, A.3
Fukuda, T.4
Kihara, N.5
Kosaku, A.6
Ohtake, H.7
Makino, S.8
-
2
-
-
33745118833
-
-
inventors; OrionPharma, assignee. Substituted β diketones and their use. U.S. patent 6,201,027. 2001 March 13
-
Aho P, Bäckström R, Koponen A, Linden I-B, Lotta T, Lönnberg K, Pippuri A, and Pohto P (2001), inventors; OrionPharma, assignee. Substituted β diketones and their use. U.S. patent 6,201,027. 2001 March 13.
-
(2001)
-
-
Aho, P.1
Bäckström, R.2
Koponen, A.3
Linden, I.-B.4
Lotta, T.5
Lönnberg, K.6
Pippuri, A.7
Pohto, P.8
-
3
-
-
0035152487
-
Cell-permeable peptide inhibitors of JNK: Novel blockers of beta-cell death
-
Bonny C, Oberson A, Negri S, Sauser C, and Schorderet DF (2001) Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death. Diabetes 50:77-82.
-
(2001)
Diabetes
, vol.50
, pp. 77-82
-
-
Bonny, C.1
Oberson, A.2
Negri, S.3
Sauser, C.4
Schorderet, D.F.5
-
4
-
-
0035208625
-
Critical role for caspases 3 and 8 in neutrophil but not eosinophil apoptosis
-
Daigle I and Simon HU (2001) Critical role for caspases 3 and 8 in neutrophil but not eosinophil apoptosis. Int Arch Allergy Immunol 126:147-156.
-
(2001)
Int Arch Allergy Immunol
, vol.126
, pp. 147-156
-
-
Daigle, I.1
Simon, H.U.2
-
5
-
-
0036565878
-
Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosis
-
De Souza PM, Kankaanranta H, Michael A, Barnes PJ, Giembycz MA, and Lindsay MA (2002) Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosis. Blood 99:3432-3438.
-
(2002)
Blood
, vol.99
, pp. 3432-3438
-
-
De Souza, P.M.1
Kankaanranta, H.2
Michael, A.3
Barnes, P.J.4
Giembycz, M.A.5
Lindsay, M.A.6
-
6
-
-
0035496905
-
Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release and activation of caspases in human eosinophils
-
Dewson G, Cohen GM, and Wardlaw AJ (2001) Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release and activation of caspases in human eosinophils. Blood 98:2239-2247.
-
(2001)
Blood
, vol.98
, pp. 2239-2247
-
-
Dewson, G.1
Cohen, G.M.2
Wardlaw, A.J.3
-
7
-
-
0141927331
-
Glucocorticoid-induced apoptosis in human eosinophils: Mechanisms of action
-
Druilhe A, Letuve S, and Pretolani M (2003) Glucocorticoid-induced apoptosis in human eosinophils: mechanisms of action. Apoptosis 8:481-495.
-
(2003)
Apoptosis
, vol.8
, pp. 481-495
-
-
Druilhe, A.1
Letuve, S.2
Pretolani, M.3
-
8
-
-
0037222933
-
Oxidant-mediated mitochondrial injury in eosinophil apoptosis: Enhancement by glucocorticoids and inhibition by granulocyte-macrophage colony-stimulating factor
-
Gardai SJ, Hoontrakoon R, Goddard CD, Day BJ, Chang LY, Henson PM, and Bratton DL (2003) Oxidant-mediated mitochondrial injury in eosinophil apoptosis: enhancement by glucocorticoids and inhibition by granulocyte-macrophage colony-stimulating factor. J Immunol 170:556-566.
-
(2003)
J Immunol
, vol.170
, pp. 556-566
-
-
Gardai, S.J.1
Hoontrakoon, R.2
Goddard, C.D.3
Day, B.J.4
Chang, L.Y.5
Henson, P.M.6
Bratton, D.L.7
-
10
-
-
0034049677
-
Mechanisms of eosinophil-associated inflammation
-
Gleich GJ (2000) Mechanisms of eosinophil-associated inflammation. J Allergy Clin Immunol 105:651-663.
-
(2000)
J Allergy Clin Immunol
, vol.105
, pp. 651-663
-
-
Gleich, G.J.1
-
11
-
-
0031709601
-
Inhibition of interleukin-5 mediated eosinophil viability by fluticasone 17-propionate: Comparison with other glucocorticoids
-
Hagan JB, Kita H, and Gleich GJ (1998) Inhibition of interleukin-5 mediated eosinophil viability by fluticasone 17-propionate: comparison with other glucocorticoids. Clin Exp Allergy 28:999-1006.
-
(1998)
Clin Exp Allergy
, vol.28
, pp. 999-1006
-
-
Hagan, J.B.1
Kita, H.2
Gleich, G.J.3
-
12
-
-
0035496902
-
Transduction of a dominant-negative H-Ras into human eosinophils attenuates extracellular signal-regulated kinase activation and interleukin-5-mediated cell viability
-
Hall DJ, Cui J, Bates ME, Stout BA, Koenderman L, Coffer PJ, and Bertics PJ (2001) Transduction of a dominant-negative H-Ras into human eosinophils attenuates extracellular signal-regulated kinase activation and interleukin-5-mediated cell viability. Blood 98:2014-2021.
-
(2001)
Blood
, vol.98
, pp. 2014-2021
-
-
Hall, D.J.1
Cui, J.2
Bates, M.E.3
Stout, B.A.4
Koenderman, L.5
Coffer, P.J.6
Bertics, P.J.7
-
13
-
-
0032472837
-
Disruption of fas receptor signaling by nitric oxide in eosinophils
-
Hebestreit H, Dibbert B, Balatti I, Braun D, Schapowal A, Blaser K, and Simon HU (1998) Disruption of fas receptor signaling by nitric oxide in eosinophils. J Exp Med 187:415-425.
-
(1998)
J Exp Med
, vol.187
, pp. 415-425
-
-
Hebestreit, H.1
Dibbert, B.2
Balatti, I.3
Braun, D.4
Schapowal, A.5
Blaser, K.6
Simon, H.U.7
-
14
-
-
0032763790
-
SB 203580, an inhibitor of p38 mitogen-activated protein kinase, enhances constitutive apoptosis of cytokine-deprived human eosinophils
-
Kankaanranta H, De Souza PM, Barnes PJ, Salmon M, Giembycz MA, and Lindsay MA (1999) SB 203580, an inhibitor of p38 mitogen-activated protein kinase, enhances constitutive apoptosis of cytokine-deprived human eosinophils. J Pharmacol Exp Ther 290:621-628.
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 621-628
-
-
Kankaanranta, H.1
De Souza, P.M.2
Barnes, P.J.3
Salmon, M.4
Giembycz, M.A.5
Lindsay, M.A.6
-
15
-
-
0033941414
-
Delayed eosinophil apoptosis in asthma
-
Kankaanranta H, Lindsay MA, Giembycz MA, Zhang X, Moilanen E, and Barnes PJ (2000a) Delayed eosinophil apoptosis in asthma. J Allergy Clin Immunol 106:77-83.
-
(2000)
J Allergy Clin Immunol
, vol.106
, pp. 77-83
-
-
Kankaanranta, H.1
Lindsay, M.A.2
Giembycz, M.A.3
Zhang, X.4
Moilanen, E.5
Barnes, P.J.6
-
16
-
-
33745117067
-
-
Chung KF and Adcock IM eds. Humana Press Inc., Totowa
-
Kankaanranta H, De Souza PM, Giembycz MA, and Lindsay MA (2000b) Human eosinophil isolation and the measurement of apoptosis in asthma: mechanisms and protocols (Chung KF and Adcock IM eds) pp 99-110, Humana Press Inc., Totowa.
-
(2000)
Human Eosinophil Isolation and the Measurement of Apoptosis in Asthma: Mechanisms and Protocols
, pp. 99-110
-
-
Kankaanranta, H.1
De Souza, P.M.2
Giembycz, M.A.3
Lindsay, M.A.4
-
17
-
-
0036125004
-
Hydrogen peroxide reverses IL-5-afforded eosinophil survival and promotes constitutive human eosinophil apoptosis
-
Kankaanranta H, Giembycz MA, Barnes PJ, Haddad E-B, Saarelainen S, Zhang X, Moilanen E, and Lindsay MA (2002) Hydrogen peroxide reverses IL-5-afforded eosinophil survival and promotes constitutive human eosinophil apoptosis. Int Arch Allergy Immunol 127:73-78.
-
(2002)
Int Arch Allergy Immunol
, vol.127
, pp. 73-78
-
-
Kankaanranta, H.1
Giembycz, M.A.2
Barnes, P.J.3
Haddad, E.-B.4
Saarelainen, S.5
Zhang, X.6
Moilanen, E.7
Lindsay, M.A.8
-
19
-
-
0042734434
-
The true face of JNK activation in apoptosis
-
Lin A and Dibling B (2002) The true face of JNK activation in apoptosis. Aging Cell 1:112-116.
-
(2002)
Aging Cell
, vol.1
, pp. 112-116
-
-
Lin, A.1
Dibling, B.2
-
20
-
-
0038004740
-
Targeting JNK for therapeutic benefit: From junk to gold?
-
Manning AM and Davis RJ (2003) Targeting JNK for therapeutic benefit: from junk to gold? Nat Rev Drug Discov 2:554-565.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 554-565
-
-
Manning, A.M.1
Davis, R.J.2
-
21
-
-
0032934674
-
Involvement of JAK2, but not PI3-kinase/Akt and MAP kinase pathways, in anti-apoptotic signals of GM-CSF in human eosinophils
-
Miike S, Nakao A, Hiraguri M, Kurasawa K, Saito Y, and Iwamoto I (1999) Involvement of JAK2, but not PI3-kinase/Akt and MAP kinase pathways, in anti-apoptotic signals of GM-CSF in human eosinophils. J Leukoc Biol 65:700-706.
-
(1999)
J Leukoc Biol
, vol.65
, pp. 700-706
-
-
Miike, S.1
Nakao, A.2
Hiraguri, M.3
Kurasawa, K.4
Saito, Y.5
Iwamoto, I.6
-
22
-
-
10344246226
-
Suppression of cytokine production and neutrophil activation by an immunomodulating agent OR-1384
-
Nissinen E, Serkkola E, Penttilä KE, Kaivola J, and Linden I-B (1997) Suppression of cytokine production and neutrophil activation by an immunomodulating agent OR-1384 (Abstract). Gastroenterology 112:A1051.
-
(1997)
Gastroenterology
, vol.112
-
-
Nissinen, E.1
Serkkola, E.2
Penttilä, K.E.3
Kaivola, J.4
Linden, I.-B.5
-
23
-
-
33745116739
-
Inhibition of neutrophil activation by a novel thiol modulating compound OR-1384
-
Nissinen E, Kaivola J, and Linden I-B (1998) Inhibition of neutrophil activation by a novel thiol modulating compound OR-1384 (Abstract). Naunyn-Schmiedeberg's Arch Pharmacol 358 (Suppl 2):R668.
-
(1998)
Naunyn-Schmiedeberg's Arch Pharmacol
, vol.358
, Issue.2 SUPPL.
-
-
Nissinen, E.1
Kaivola, J.2
Linden, I.-B.3
-
24
-
-
33745132543
-
Efficacy of a new anti-inflammatory compound, orazipone, in the models of airway eosinophilia in rat and guinea pigs
-
Ruotsalainen M, Koponen A, Nissinen E, and Hyttilä M (2000) Efficacy of a new anti-inflammatory compound, orazipone, in the models of airway eosinophilia in rat and guinea pigs (Abstract). Eur Respir J 16 (Suppl 31):s560.
-
(2000)
Eur Respir J
, vol.16
, Issue.31 SUPPL.
-
-
Ruotsalainen, M.1
Koponen, A.2
Nissinen, E.3
Hyttilä, M.4
-
25
-
-
0037468687
-
The hypereosinophilic syndrome and the biology of cancer
-
Schwartz RS (2003) The hypereosinophilic syndrome and the biology of cancer. N Engl J Med 348:1199-1200.
-
(2003)
N Engl J Med
, vol.348
, pp. 1199-1200
-
-
Schwartz, R.S.1
-
26
-
-
33745139298
-
The effect of orazipone on LPS-induced IL-1β and TNFα production
-
Serkkola E and Nissinen E (1999) The effect of orazipone on LPS-induced IL-1β and TNFα production (Abstract). Med Inflammation 8:S84.
-
(1999)
Med Inflammation
, vol.8
-
-
Serkkola, E.1
Nissinen, E.2
-
27
-
-
10344247644
-
The novel sulfhydryl-reactive compounds orazipone and OR-1958 inhibit cytokine production in rat and human (HMC-1) mast cells
-
Vendelin J, Laitinen C, Vainio P, Nissinen E, Mäki T, and Eklund KK (2005) The novel sulfhydryl-reactive compounds orazipone and OR-1958 inhibit cytokine production in rat and human (HMC-1) mast cells. Int Immunopharmacol 5:177-184.
-
(2005)
Int Immunopharmacol
, vol.5
, pp. 177-184
-
-
Vendelin, J.1
Laitinen, C.2
Vainio, P.3
Nissinen, E.4
Mäki, T.5
Eklund, K.K.6
-
28
-
-
0033060178
-
Evaluation of apoptosis of eosinophils, macrophages and T lymphocytes in mucosal biopsy specimens of patients with asthma and chronic bronchitis
-
Vignola AM, Chanez P, Chiappara G, Siena L, Merendino A, and Reina C (1999) Evaluation of apoptosis of eosinophils, macrophages and T lymphocytes in mucosal biopsy specimens of patients with asthma and chronic bronchitis. J Allergy Clin Immunol 103:563-573.
-
(1999)
J Allergy Clin Immunol
, vol.103
, pp. 563-573
-
-
Vignola, A.M.1
Chanez, P.2
Chiappara, G.3
Siena, L.4
Merendino, A.5
Reina, C.6
-
29
-
-
0642366134
-
Regulation of granulocyte apoptosis by hemopoietic growth factors, cytokines and drugs: Potential relevance to allergic inflammation
-
Walker A, Ward C, Dransfield I, Haslett C, and Rossi AG (2003) Regulation of granulocyte apoptosis by hemopoietic growth factors, cytokines and drugs: potential relevance to allergic inflammation. Curr Drug Targets Inflamm Allergy 2:339-347.
-
(2003)
Curr Drug Targets Inflamm Allergy
, vol.2
, pp. 339-347
-
-
Walker, A.1
Ward, C.2
Dransfield, I.3
Haslett, C.4
Rossi, A.G.5
-
30
-
-
0041669300
-
Mechanisms of steroid action and resistance in inflammation: Corticosteroids, eosinophils and bronchial epithelial cells: new insights into the resolution of inflammation in asthma
-
Walsh GM, Sexton DW, and Blaylock MG (2003) Mechanisms of steroid action and resistance in inflammation: corticosteroids, eosinophils and bronchial epithelial cells: new insights into the resolution of inflammation in asthma. J Endocrinol 178:37-43.
-
(2003)
J Endocrinol
, vol.178
, pp. 37-43
-
-
Walsh, G.M.1
Sexton, D.W.2
Blaylock, M.G.3
-
31
-
-
0030882371
-
Delayed eosinophil programmed cell death in vitro: A common feature of inhalant allergy and extrinsic and intrinsic atopic dermatitis
-
Wedi B, Raap U, Lewrick H, and Kapp A (1997) Delayed eosinophil programmed cell death in vitro: a common feature of inhalant allergy and extrinsic and intrinsic atopic dermatitis. J Allergy Clin Immunol 100:536-543.
-
(1997)
J Allergy Clin Immunol
, vol.100
, pp. 536-543
-
-
Wedi, B.1
Raap, U.2
Lewrick, H.3
Kapp, A.4
-
32
-
-
0033214683
-
Eosinophil apoptosis is mediated by stimulators of cellular oxidative metabolisms and inhibited by antioxidants: Involvement of a thiol-sensitive redox regulation in eosinophil death
-
Wedi B, Straede J, Wieland B, and Kapp A (1999) Eosinophil apoptosis is mediated by stimulators of cellular oxidative metabolisms and inhibited by antioxidants: involvement of a thiol-sensitive redox regulation in eosinophil death. Blood 94:2365-2373.
-
(1999)
Blood
, vol.94
, pp. 2365-2373
-
-
Wedi, B.1
Straede, J.2
Wieland, B.3
Kapp, A.4
-
34
-
-
0034107113
-
Effect of IL-5, glucocorticoid and Fas ligation on Bcl-2 homologue expression and caspase activation in circulating human eosinophils
-
Zangrilli J, Robertson N, Shetty A, Wu J, Hastie A, Fish JE, Litwack G, and Peters SP (2000) Effect of IL-5, glucocorticoid and Fas ligation on Bcl-2 homologue expression and caspase activation in circulating human eosinophils. Clin Exp Immunol 120:12-21.
-
(2000)
Clin Exp Immunol
, vol.120
, pp. 12-21
-
-
Zangrilli, J.1
Robertson, N.2
Shetty, A.3
Wu, J.4
Hastie, A.5
Fish, J.E.6
Litwack, G.7
Peters, S.P.8
-
35
-
-
0037119038
-
Divergent effect of mometasone on human eosinophil and neutrophil apoptosis
-
Zhang X, Moilanen E, Adcock IM, Lindsay MA, and Kankaanranta H (2002) Divergent effect of mometasone on human eosinophil and neutrophil apoptosis. Life Sci 71:1523-1534.
-
(2002)
Life Sci
, vol.71
, pp. 1523-1534
-
-
Zhang, X.1
Moilanen, E.2
Adcock, I.M.3
Lindsay, M.A.4
Kankaanranta, H.5
-
36
-
-
0034693075
-
Enhancement of human eosinophil apoptosis by fluticasone propionate, budesonide and beclomethasone
-
Zhang X, Moilanen E, and Kankaanranta H (2000) Enhancement of human eosinophil apoptosis by fluticasone propionate, budesonide and beclomethasone. Eur J Pharmacol 406:325-332.
-
(2000)
Eur J Pharmacol
, vol.406
, pp. 325-332
-
-
Zhang, X.1
Moilanen, E.2
Kankaanranta, H.3
-
37
-
-
0037662016
-
Regulation of eosinophil apoptosis by nitric oxide: Role of c-jun-N-terminal kinase and signal transducer and activator of transcription 5
-
Zhang X, Moilanen E, Lahti A, Hamalainen M, Giembycz MA, Barnes PJ, Lindsay MA, and Kankaanranta H (2003) Regulation of eosinophil apoptosis by nitric oxide: role of c-jun-N-terminal kinase and signal transducer and activator of transcription 5. J Allergy Clin Immunol 112:93-101.
-
(2003)
J Allergy Clin Immunol
, vol.112
, pp. 93-101
-
-
Zhang, X.1
Moilanen, E.2
Lahti, A.3
Hamalainen, M.4
Giembycz, M.A.5
Barnes, P.J.6
Lindsay, M.A.7
Kankaanranta, H.8
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