Histamine reverses IL-5-afforded human eosinophil survival by inducing apoptosis: Pharmacological evidence for a novel mechanism of action of histamine

Pulmonary Pharmacology and Therapeutics

Volumn 21, Issue 1, 2008, Pages 222-233

  Hasala, Hannele ^a,c   Giembycz, Mark A ^b   Janka Junttila, Mirkka ^a,c   Moilanen, Eeva ^a,c   Kankaanranta, Hannu ^a,c  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b UNIVERSITY OF CALGARY   (Canada)

^c TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

Apoptosis; Caspases; Eosinophils; Histamine; Histamine receptors; IL 5

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; ANTIHISTAMINIC AGENT; CASPASE; CASPASE 10; CASPASE 12; CASPASE 6; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; HISTAMINE; HISTAMINE AGONIST; HISTAMINE RECEPTOR; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 5; PHOSPHOLIPASE C; PROPIDIUM IODIDE; RECEPTOR SUBTYPE; SEROTONIN RECEPTOR;

APOPTOSIS; ARTICLE; BRIGHT FIELD MICROSCOPY; CELL CULTURE; CELL ISOLATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DIAGNOSTIC KIT; DNA CONTENT; ENZYME ACTIVITY; ENZYME INHIBITION; EOSINOPHIL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUMINESCENCE; PRIORITY JOURNAL; SECOND MESSENGER; SIGNAL TRANSDUCTION;

APOPTOSIS; CASPASES; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EOSINOPHILS; HISTAMINE; HUMANS; INTERLEUKIN-5; RECEPTORS, ADRENERGIC, ALPHA; RECEPTORS, HISTAMINE; RECEPTORS, SEROTONIN; SIGNAL TRANSDUCTION;

EID: 38049094235     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2007.03.002     Document Type: Article

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