메뉴 건너뛰기




Volumn 231, Issue 6, 2014, Pages 1167-1189

Neuroimaging endophenotypes in animal models of autism spectrum disorders: Lost or found in translation?

Author keywords

Animal models; Autism; CNV; Endophenotypes; MRI; MRS; Serotonin; Synaptic cell adhesion molecules; Syndromic ASD; Valproic acid

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; BETA3 INTEGRIN; INTERLEUKIN 6; NEUROLIGIN;

EID: 84896712956     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-013-3200-z     Document Type: Review
Times cited : (8)

References (263)
  • 1
    • 42349095075 scopus 로고    scopus 로고
    • Advances in autism genetics: On the threshold of a new neurobiology
    • DOI 10.1038/nrg2346, PII NRG2346
    • Abrahams BS, Geschwind DH (2008) Advances in autism genetics: on the threshold of a new neurobiology. Nat Rev Genet 9:341-355 (Pubitemid 351556064)
    • (2008) Nature Reviews Genetics , vol.9 , Issue.5 , pp. 341-355
    • Abrahams, B.S.1    Geschwind, D.H.2
  • 3
    • 80755152681 scopus 로고    scopus 로고
    • The cerebellum in autism
    • Allen G (2005) The cerebellum in autism. Clin Neuropsychiatry 2:321-337
    • (2005) Clin Neuropsychiatry , vol.2 , pp. 321-337
    • Allen, G.1
  • 7
    • 84870469320 scopus 로고    scopus 로고
    • American Psychiatric Association 4th edn. American Psychiatric Association, Washington, text revision
    • American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Association, Washington, p 84, text revision
    • (2000) Diagnostic and Statistical Manual of Mental Disorders , pp. 84
  • 8
    • 80054960716 scopus 로고    scopus 로고
    • Review of neuroimaging in autism spectrum disorders: What have we learned and where we go from here
    • Anagnostou E, Taylor MJ (2011) Review of neuroimaging in autism spectrum disorders: what have we learned and where we go from here. Mol Autism 2:4
    • (2011) Mol Autism , vol.2 , pp. 4
    • Anagnostou, E.1    Taylor, M.J.2
  • 9
    • 84856305812 scopus 로고    scopus 로고
    • Age-related change in brain metabolite abnormalities in autism: A meta-analysis of proton magnetic resonance spectroscopy studies
    • Aoki Y, Kasai K, Yamasue H (2012) Age-related change in brain metabolite abnormalities in autism: a meta-analysis of proton magnetic resonance spectroscopy studies. Transl Psychiatry 2:e69
    • (2012) Transl Psychiatry , vol.2
    • Aoki, Y.1    Kasai, K.2    Yamasue, H.3
  • 10
    • 0035201049 scopus 로고    scopus 로고
    • Rett syndrome neuropathology review 2000
    • Armstrong DD (2001) Rett syndrome neuropathology review 2000. Brain Dev 23:72-76
    • (2001) Brain Dev , vol.23 , pp. 72-76
    • Armstrong, D.D.1
  • 11
    • 27144534968 scopus 로고    scopus 로고
    • Neuropathology of Rett syndrome
    • Armstrong DD (2005) Neuropathology of Rett syndrome. J Child Neurol 20:747-753
    • (2005) J Child Neurol , vol.20 , pp. 747-753
    • Armstrong, D.D.1
  • 18
    • 1642441704 scopus 로고    scopus 로고
    • White matter structure in autism: Preliminary evidence from diffusion tensor imaging
    • DOI 10.1016/j.biopsych.2003.10.022
    • Barnea-Goraly N, Kwon H, Menon V, Eliez S, Lotspeich L, Reiss AL (2004) White matter structure in autism: preliminary evidence from diffusion tensor imaging. Biol Psychiatry 55:323-326 (Pubitemid 38117172)
    • (2004) Biological Psychiatry , vol.55 , Issue.3 , pp. 323-326
    • Barnea-Goraly, N.1    Kwon, H.2    Menon, V.3    Eliez, S.4    Lotspeich, L.5    Reiss, A.L.6
  • 20
    • 0021838287 scopus 로고
    • Histoanatomic observations of the brain in early infantile autism
    • Bauman M, Kemper TL (1985) Histoanatomic observations of the brain in early infantile autism. Neurology 35:866-874 (Pubitemid 15025292)
    • (1985) Neurology , vol.35 , Issue.6 , pp. 866-874
    • Bauman, M.1    Kemper, T.L.2
  • 21
    • 14644395605 scopus 로고    scopus 로고
    • Neuroanatomic observations of the brain in autism: A review and future directions
    • DOI 10.1016/j.ijdevneu.2004.09.006
    • Bauman ML, Kemper TL (2005) Neuroanatomic observations of the brain in autism: a review and future directions. Int J Dev Neurosci 23:183-187 (Pubitemid 40313551)
    • (2005) International Journal of Developmental Neuroscience , vol.23 , Issue.2-3 SPEC. ISS. , pp. 183-187
    • Bauman, M.L.1    Kemper, T.L.2
  • 22
    • 67349129763 scopus 로고    scopus 로고
    • Reward circuitry is perturbed in the absence of the serotonin transporter
    • Bearer EL, Zhang X, Janvelyan D, Boulat B, Jacobs RE (2009) Reward circuitry is perturbed in the absence of the serotonin transporter. NeuroImage 46:1091-1104
    • (2009) NeuroImage , vol.46 , pp. 1091-1104
    • Bearer, E.L.1    Zhang, X.2    Janvelyan, D.3    Boulat, B.4    Jacobs, R.E.5
  • 23
    • 35248856059 scopus 로고    scopus 로고
    • Olfaction and Taste Processing in Autism
    • DOI 10.1016/j.biopsych.2007.04.019, PII S000632230700371X, Autism and Attention Defecit Hyperactivity Disorder
    • Bennetto L, Kuschner ES, Hyman SL (2007) Olfaction and taste processing in autism. Biol Psychiatry 62:1015-1021 (Pubitemid 47562372)
    • (2007) Biological Psychiatry , vol.62 , Issue.9 , pp. 1015-1021
    • Bennetto, L.1    Kuschner, E.S.2    Hyman, S.L.3
  • 24
    • 1642399711 scopus 로고    scopus 로고
    • Profound impairment in social recognition and reduction in anxiety-like behavior in vasopressin V1a receptor knockout mice
    • DOI 10.1038/sj.npp.1300360
    • Bielsky IF, Hu SB, Szegda KL, Westpahl H, Joung LJ (2004) Profound impairment in social recognition and reduction in anxiety-like behaviour in vasopressin V1a receptor knockout mice. Neuropsychopharmacology 29:483-493 (Pubitemid 38372087)
    • (2004) Neuropsychopharmacology , vol.29 , Issue.3 , pp. 483-493
    • Bielsky, I.F.1    Hu, S.-B.2    Szegda, K.L.3    Westphal, H.4    Young, L.J.5
  • 25
    • 0021916149 scopus 로고
    • The distribution and origin of serotonin immunoreactivity in the rat cerebellum
    • DOI 10.1016/0006-8993(85)91545-8
    • Bishop GA, Ho RH (1985) The distribution and origin of serotonin immunoreactivity in the rat cerebellum. Brain Res 331:195-207 (Pubitemid 15115329)
    • (1985) Brain Research , vol.331 , Issue.2 , pp. 195-207
    • Bishop, G.A.1    Ho, R.H.2
  • 26
    • 84875439709 scopus 로고    scopus 로고
    • Changes in prevalence of parent-reported autism spectrum disorder in school-aged U.S. children: 2007 to 2011-2012
    • no 65. National Center for Health Statistics, Hyattsville
    • Blumberg SJ, Bramlett MD, Kogan MD, Schieve LA, Jones JR, Lu MC (2013) Changes in prevalence of parent-reported autism spectrum disorder in school-aged U.S. children: 2007 to 2011-2012. National Health Statistics Reportes; no 65. National Center for Health Statistics, Hyattsville
    • (2013) National Health Statistics Reportes
    • Blumberg, S.J.1    Bramlett, M.D.2    Kogan, M.D.3    Schieve, L.A.4    Jones, J.R.5    Lu, M.C.6
  • 27
    • 0035955643 scopus 로고    scopus 로고
    • Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain Shank protein family interact with cytoskeletal protein alpha-fodrin
    • Bockers TM, Mameza MG, Kreutz MR, Bockmann J, Weise C, Buck F, Richter D, Gundelfinger ED, Kreienkamp HJ (2001) Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain Shank protein family interact with cytoskeletal protein alpha-fodrin. J Biol Chem 276:40104-40112
    • (2001) J Biol Chem , vol.276 , pp. 40104-40112
    • Bockers, T.M.1    Mameza, M.G.2    Kreutz, M.R.3    Bockmann, J.4    Weise, C.5    Buck, F.6    Richter, D.7    Gundelfinger, E.D.8    Kreienkamp, H.J.9
  • 28
    • 84896701920 scopus 로고    scopus 로고
    • Assessing autism-like behaviour in mice: Variations in social interactions among inbred strains
    • Bolivar VJ, Walters SR, Phoenix JL (2007) Assessing autism-like behaviour in mice: variations in social interactions among inbred strains. Behav Brain Res 233:99-104
    • (2007) Behav Brain Res , vol.233 , pp. 99-104
    • Bolivar, V.J.1    Walters, S.R.2    Phoenix, J.L.3
  • 29
    • 84907273902 scopus 로고    scopus 로고
    • Genetic basis of autism
    • Moldin SO, Rubenstein JL (eds) CRC Press, Taylor and Francis Group, Boca Raton
    • Bonora E, Lamb JA, Barnby G, Bailey AJ, Monaco AP (2006) Genetic basis of autism. In: Moldin SO, Rubenstein JL (eds) Understanding autism. CRC Press, Taylor and Francis Group, Boca Raton, pp 49-74
    • (2006) Understanding Autism , pp. 49-74
    • Bonora, E.1    Lamb, J.A.2    Barnby, G.3    Bailey, A.J.4    Monaco, A.P.5
  • 30
    • 51249118269 scopus 로고    scopus 로고
    • Monoamine oxidase inactivation: From pathophysiology to therapeutics
    • Bortolato M, Chen K, Shih JC (2008) Monoamine oxidase inactivation: from pathophysiology to therapeutics. Adv Drug Deliv Rev 60:1527-1533
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1527-1533
    • Bortolato, M.1    Chen, K.2    Shih, J.C.3
  • 34
    • 33845319742 scopus 로고    scopus 로고
    • Balb/c mice: Low sociability and other phenotypes that may be relevant to autism
    • Brodkin ES (2007) Balb/c mice: low sociability and other phenotypes that may be relevant to autism. Behav Brain Res 176:53-65
    • (2007) Behav Brain Res , vol.176 , pp. 53-65
    • Brodkin, E.S.1
  • 35
    • 1342279438 scopus 로고    scopus 로고
    • Social approach-avoidance behavior of inbred mouse strains towards DBA/2 mice
    • DOI 10.1016/j.brainres.2003.12.013
    • Brodkin ES, Hagemann A, Nemetski SM, Silver LM (2004) Social approach-avoidance behaviour of inbred mouse strains towards DBA/2 mice. Brain Res 1002:151-157 (Pubitemid 38251589)
    • (2004) Brain Research , vol.1002 , Issue.1-2 , pp. 151-157
    • Brodkin, E.S.1    Hagemann, A.2    Nemetski, S.M.3    Silver, L.M.4
  • 36
    • 63849307686 scopus 로고    scopus 로고
    • Autism spectrum disorders following in utero exposure to antiepileptic drugs
    • Bromley RL, Mawer G, Clayton-Smith J, Baker GA (2008) Autism spectrum disorders following in utero exposure to antiepileptic drugs. Neurology 71:1923-1924
    • (2008) Neurology , vol.71 , pp. 1923-1924
    • Bromley, R.L.1    Mawer, G.2    Clayton-Smith, J.3    Baker, G.A.4
  • 37
    • 84871371945 scopus 로고    scopus 로고
    • The autism sequencing consortium: Large-scale, high-throughput sequencing in autism spectrum disorders
    • Buxbaum JD, Daly MJ, Devlin B, Lehner T, Roeder K, State MW (2012) The autism sequencing consortium: large-scale, high-throughput sequencing in autism spectrum disorders. Neuron 76:1052-1056
    • (2012) Neuron , vol.76 , pp. 1052-1056
    • Buxbaum, J.D.1    Daly, M.J.2    Devlin, B.3    Lehner, T.4    Roeder, K.5    State, M.W.6
  • 39
    • 78751513645 scopus 로고    scopus 로고
    • Experimental models of Rett syndrome based on Mecp2 dysfunction
    • Calfa G, Percy AK, Pozzo-Miller L (2011) Experimental models of Rett syndrome based on Mecp2 dysfunction. Exp Biol Med 236:3-19
    • (2011) Exp Biol Med , vol.236 , pp. 3-19
    • Calfa, G.1    Percy, A.K.2    Pozzo-Miller, L.3
  • 40
    • 79951574616 scopus 로고    scopus 로고
    • Absence of preference for social novelty and increased grooming in integrin β3 knockout mice: Initial studies and future directions
    • Carter MD, Shah CR, Muller CL, Crawley JN, Carneiro AMD, Veenstra-VanderWeele J (2011) Absence of preference for social novelty and increased grooming in integrin β3 knockout mice: initial studies and future directions. Autism Res 4:57-67
    • (2011) Autism Res , vol.4 , pp. 57-67
    • Carter, M.D.1    Shah, C.R.2    Muller, C.L.3    Crawley, J.N.4    Carneiro, A.M.D.5    Veenstra-VanderWeele, J.6
  • 43
    • 8344271952 scopus 로고    scopus 로고
    • Influence of MECP2 gene mutation and x-chromosome inactivation on the Rett syndrome phenotype
    • Chae JH, Hwang H, Hwang YS, Cheong HJ, Kim KJ (2004) Influence of MECP2 gene mutation and X-chromosome inactivation on the Rett syndrome phenotype. J Child Neurol 19:503-508 (Pubitemid 39481249)
    • (2004) Journal of Child Neurology , vol.19 , Issue.7 , pp. 503-508
    • Chae, J.H.1    Hwang, H.2    Hwang, Y.S.3    Cheong, H.J.4    Kim, K.J.5
  • 44
    • 35648978121 scopus 로고    scopus 로고
    • The Story of Rett Syndrome: From Clinic to Neurobiology
    • DOI 10.1016/j.neuron.2007.10.001, PII S0896627307007568
    • Chahrour M, Zoghbi HY (2007) The story of Rett syndrome: from clinic to neurobiology. Neuron 56:422-437 (Pubitemid 350026269)
    • (2007) Neuron , vol.56 , Issue.3 , pp. 422-437
    • Chahrour, M.1    Zoghbi, H.Y.2
  • 46
    • 0035093830 scopus 로고    scopus 로고
    • Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
    • DOI 10.1038/85906
    • Chen RZ, Akbarian S, Tudor M, Jaenisch R (2001) Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat Genet 27:327-331 (Pubitemid 32201857)
    • (2001) Nature Genetics , vol.27 , Issue.3 , pp. 327-331
    • Chen, R.Z.1    Akbarian, S.2    Tudor, M.3    Jaenisch, R.4
  • 47
    • 79954627753 scopus 로고    scopus 로고
    • Structural MRI in autism spectrum disorder
    • Chen R, Jiao Y, Herskovits EH (2011) Structural MRI in autism spectrum disorder. Pediatr Res 69:63-68
    • (2011) Pediatr Res , vol.69 , pp. 63-68
    • Chen, R.1    Jiao, Y.2    Herskovits, E.H.3
  • 49
    • 0032987647 scopus 로고    scopus 로고
    • Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children
    • DOI 10.1002/1531-8249(199903)45:3<287::AID-ANA3
    • Chugani DC, Muzik O, Behen M, Rothermel R, Janisse JJ, Lee J, Chugani HT (1999) Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children. Ann Neurol 45:287-295 (Pubitemid 29120032)
    • (1999) Annals of Neurology , vol.45 , Issue.3 , pp. 287-295
    • Chugani, D.C.1    Muzik, O.2    Behen, M.3    Rothermel, R.4    Janisse, J.J.5    Lee, J.6    Chugani, H.T.7
  • 50
    • 4344682582 scopus 로고    scopus 로고
    • Less white matter concentration in autism: 2D voxel-based morphometry
    • DOI 10.1016/j.neuroimage.2004.04.037, PII S1053811904002290
    • Chung MK, Dalton KM, Alexander AL, Davidson RJ (2004) Less white matter concentration in autism: 2D voxel-based morphometry. NeuroImage 23:242-251 (Pubitemid 39119454)
    • (2004) NeuroImage , vol.23 , Issue.1 , pp. 242-251
    • Chung, M.K.1    Dalton, K.M.2    Alexander, A.L.3    Davidson, R.J.4
  • 51
    • 0035986909 scopus 로고    scopus 로고
    • Structural and functional magnetic resonance imaging of autism
    • Cody H, Pelphrey K, Piven J (2002) Structural and functional magnetic resonance imaging of autism. Int J Dev Neurosci 20:421-438
    • (2002) Int J Dev Neurosci , vol.20 , pp. 421-438
    • Cody, H.1    Pelphrey, K.2    Piven, J.3
  • 53
    • 10544234621 scopus 로고    scopus 로고
    • The serotonin system in autism
    • Cook E, Leventhal B (1996) The serotonin system in autism. Curr Opin Pediatr 8:348-354
    • (1996) Curr Opin Pediatr , vol.8 , pp. 348-354
    • Cook, E.1    Leventhal, B.2
  • 54
    • 4944227121 scopus 로고    scopus 로고
    • Brain development in autism: Early overgrowth followed by premature arrest of growth
    • Courchesne E (2004) Brain development in autism: early overgrowth followed by premature arrest of growth. Ment Retard Dev Disabil Res Rev 10:106-111
    • (2004) Ment Retard Dev Disabil Res Rev , vol.10 , pp. 106-111
    • Courchesne, E.1
  • 60
    • 35148821488 scopus 로고    scopus 로고
    • Mouse behavioural assays relevant to the symptoms of autism
    • Crawley JN (2007) Mouse behavioural assays relevant to the symptoms of autism. Brain Pathol 17:448-459
    • (2007) Brain Pathol , vol.17 , pp. 448-459
    • Crawley, J.N.1
  • 63
    • 33846585891 scopus 로고    scopus 로고
    • Evidence for Cortical Dysfunction in Autism: A Proton Magnetic Resonance Spectroscopic Imaging Study
    • DOI 10.1016/j.biopsych.2006.07.022, PII S0006322306009334, Advances in Understending and Treating Autism Spectrum Disorders
    • DeVito TJ, Drost DJ, Neufeld RW, Rajakumar N, Pavlosky W, Williamson P, Nicolson R (2007) Evidence for cortical dysfunction in autism: a proton magnetic resonance spectroscopic imaging study. Biol Psychiatry 61:465-473 (Pubitemid 46185338)
    • (2007) Biological Psychiatry , vol.61 , Issue.4 , pp. 465-473
    • DeVito, T.J.1    Drost, D.J.2    Neufeld, R.W.J.3    Rajakumar, N.4    Pavlosky, W.5    Williamson, P.6    Nicolson, R.7
  • 64
    • 57049102842 scopus 로고    scopus 로고
    • Functional brain correlates of social and non-social processes in autism spectrum disorders: An activation likelihood estimation meta-analysis
    • Di Martino A, Ross K, Uddin LQ, Sklar AB, Castellanos FX, Milham MP (2009) Functional brain correlates of social and non-social processes in autism spectrum disorders: an activation likelihood estimation meta-analysis. Biol Psychiatry 65:63-74
    • (2009) Biol Psychiatry , vol.65 , pp. 63-74
    • Di Martino, A.1    Ross, K.2    Uddin, L.Q.3    Sklar, A.B.4    Castellanos, F.X.5    Milham, M.P.6
  • 65
    • 73449103400 scopus 로고    scopus 로고
    • Fragile X syndrome and autism: From disease model to therapeutic targets
    • Dolen G, Bear MF (2009) Fragile X syndrome and autism: from disease model to therapeutic targets. J Neurodev Disord 1:133-140
    • (2009) J Neurodev Disord , vol.1 , pp. 133-140
    • Dolen, G.1    Bear, M.F.2
  • 66
    • 0029135317 scopus 로고
    • Reduced size of corpus callosum in autism
    • Egaas B, Chourchesne E, Saitoh O (1995) Reduced size of corpus callosum in autism. Arch Neurol 52:794-801
    • (1995) Arch Neurol , vol.52 , pp. 794-801
    • Egaas, B.1    Chourchesne, E.2    Saitoh, O.3
  • 67
    • 77956211293 scopus 로고    scopus 로고
    • Anatomical phenotyping in a mouse model of fragile X syndrome with magnetic resonance imaging
    • Ellegood J, Pacey LK, Hampson DR, Lerch JP, Henkelman RM (2010) Anatomical phenotyping in a mouse model of fragile X syndrome with magnetic resonance imaging. NeuroImage 53:1023-1029
    • (2010) NeuroImage , vol.53 , pp. 1023-1029
    • Ellegood, J.1    Pacey, L.K.2    Hampson, D.R.3    Lerch, J.P.4    Henkelman, R.M.5
  • 68
    • 80053913696 scopus 로고    scopus 로고
    • Brain abnormalities in a neuroligin3 R451C knockin mouse model associated with autism
    • Ellegood J, Lerch JP, Henkelman RM (2011) Brain abnormalities in a neuroligin3 R451C knockin mouse model associated with autism. Autism Res 4:368-376
    • (2011) Autism Res , vol.4 , pp. 368-376
    • Ellegood, J.1    Lerch, J.P.2    Henkelman, R.M.3
  • 69
    • 84866842812 scopus 로고    scopus 로고
    • Neuroanatomical assessment of the integrin β3 mouse model related to autism and the serotonin system using high resolution MRI
    • doi:10.1016/j.neuroimage.2012.12.029
    • Ellegood J, Henkelman RM, Lerch JP (2012) Neuroanatomical assessment of the integrin β3 mouse model related to autism and the serotonin system using high resolution MRI. Front Psychiatry. doi:10.1016/j.neuroimage.2012.12. 029
    • (2012) Front Psychiatry
    • Ellegood, J.1    Henkelman, R.M.2    Lerch, J.P.3
  • 70
    • 84872714279 scopus 로고    scopus 로고
    • Neuroanatomical analysis of the BTBR mouse model of autism using magnetic resonance imaging and diffusion tensor imaging
    • Ellegood J, Babineau BA, Henkelman RM, Lerch JP, Crawley JN (2013a) Neuroanatomical analysis of the BTBR mouse model of autism using magnetic resonance imaging and diffusion tensor imaging. NeuroImage 70:288-300
    • (2013) NeuroImage , vol.70 , pp. 288-300
    • Ellegood, J.1    Babineau, B.A.2    Henkelman, R.M.3    Lerch, J.P.4    Crawley, J.N.5
  • 71
    • 84896718100 scopus 로고    scopus 로고
    • Using volumetric measures of neuroanatomy to cluster multiple mouse models of autism
    • Ellegood J, Henkelman RM, Lerch JP (2013b) Using volumetric measures of neuroanatomy to cluster multiple mouse models of autism. Proc Int Soc Magn Reson Med 21:1041
    • (2013) Proc Int Soc Magn Reson Med , vol.21 , pp. 1041
    • Ellegood, J.1    Henkelman, R.M.2    Lerch, J.P.3
  • 74
    • 84861203989 scopus 로고    scopus 로고
    • Gestational valproate alters BOLD activation in response to complex social and primary sensory stimuli
    • Felix-Ortiz A, Febo M (2012) Gestational valproate alters BOLD activation in response to complex social and primary sensory stimuli. PLoS One 5:e37313
    • (2012) PLoS One , vol.5
    • Felix-Ortiz, A.1    Febo, M.2
  • 76
    • 0019469515 scopus 로고
    • Effects of precursors on brain neurotransmitter synthesis and brain functions
    • Fernstrom JD (1981) Effects of precursors on brain neurotransmitter synthesis and brain functions. Diabetologia 20:281-289
    • (1981) Diabetologia , vol.20 , pp. 281-289
    • Fernstrom, J.D.1
  • 77
  • 78
    • 0017337957 scopus 로고
    • Genetic influences and infantile autism
    • DOI 10.1038/265726a0
    • Folstein S, Rutter M (1977) Genetic influences and infantile autism. Nature 24:726-728 (Pubitemid 8039452)
    • (1977) Nature , vol.265 , Issue.5596 , pp. 726-728
    • Folstein, S.1    Rutter, M.2
  • 79
    • 0032804766 scopus 로고    scopus 로고
    • The epidemiology of autism: A review
    • Fombonne E (1999) The epidemiology of autism: a review. Psychol Med 29:769-786
    • (1999) Psychol Med , vol.29 , pp. 769-786
    • Fombonne, E.1
  • 80
    • 31144444162 scopus 로고    scopus 로고
    • Epidemiology of autistic disorder and other pervasive developmental disorders
    • Fombonne E (2005) Epidemiology of autistic disorder and other pervasive developmental disorders. J Clin Psychiatry 66:3-8
    • (2005) J Clin Psychiatry , vol.66 , pp. 3-8
    • Fombonne, E.1
  • 81
    • 33845797961 scopus 로고    scopus 로고
    • The genetics of autistic disorders and its clinical relevance: A review of the literature
    • Freitag CM (2007) The genetics of autistic disorders and its clinical relevance: a review of the literature. Mol Psychiatry 12:2-22
    • (2007) Mol Psychiatry , vol.12 , pp. 2-22
    • Freitag, C.M.1
  • 83
    • 66849138564 scopus 로고    scopus 로고
    • Dose-dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat
    • Frisch C, Husch K, Angenstein F, Kudin A, Kunz W, Elger CE, Helmstaedter C (2009) Dose-dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat. Epilepsia 50:1432-1441
    • (2009) Epilepsia , vol.50 , pp. 1432-1441
    • Frisch, C.1    Husch, K.2    Angenstein, F.3    Kudin, A.4    Kunz, W.5    Elger, C.E.6    Helmstaedter, C.7
  • 84
    • 77749277378 scopus 로고    scopus 로고
    • Function of the frontal lobe in autistic individuals: A proton magnetic resonance spectroscopic study
    • Fujii E, Mori K, Miyazaki M, Hashimoto T, Harada M, Kagami S (2010) Function of the frontal lobe in autistic individuals: a proton magnetic resonance spectroscopic study. J Med Investig 57:35-44
    • (2010) J Med Investig , vol.57 , pp. 35-44
    • Fujii, E.1    Mori, K.2    Miyazaki, M.3    Hashimoto, T.4    Harada, M.5    Kagami, S.6
  • 85
    • 67650732715 scopus 로고    scopus 로고
    • Advances in autism
    • Geschwind DH(2009) Advances in autism. Annu Rev Med 60:367-380
    • (2009) Annu Rev Med , vol.60 , pp. 367-380
    • Geschwind, D.H.1
  • 86
    • 80051920294 scopus 로고    scopus 로고
    • Genetics of autism spectrum disorders
    • Geschwind DH (2011) Genetics of autism spectrum disorders. Trends Cogn Sci 15:409-416
    • (2011) Trends Cogn Sci , vol.15 , pp. 409-416
    • Geschwind, D.H.1
  • 87
    • 33846921789 scopus 로고    scopus 로고
    • Autism spectrum disorders: Developmental disconnection syndromes
    • DOI 10.1016/j.conb.2007.01.009, PII S0959438807000116
    • Geschwind DH, Levitt P (2007) Autism spectrum disorders: developmental disconnection syndromes. Curr Opin Neurobiol 17:103-111 (Pubitemid 46237744)
    • (2007) Current Opinion in Neurobiology , vol.17 , Issue.1 , pp. 103-111
    • Geschwind, D.H.1    Levitt, P.2
  • 89
    • 0035192560 scopus 로고    scopus 로고
    • Magnetic resonance imaging and clinical findings examined in adulthood-studies on three adults with Rett syndrome
    • Gotoh H, Suzuki I, Maruki K, Mitomo M, Hirasawa K, Sasaki N (2001) Magnetic resonance imaging and clinical findings examined in adulthood-studies on three adults with Rett syndrome. Brain Dev 23:118-121
    • (2001) Brain Dev , vol.23 , pp. 118-121
    • Gotoh, H.1    Suzuki, I.2    Maruki, K.3    Mitomo, M.4    Hirasawa, K.5    Sasaki, N.6
  • 90
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • DOI 10.1176/appi.ajp.160.4.636
    • Gottesman II, Gould TD (2003) The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 160:636-645 (Pubitemid 41079594)
    • (2003) American Journal of Psychiatry , vol.160 , Issue.4 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 92
    • 0035094767 scopus 로고    scopus 로고
    • A mouse Mecp2-null mutation causes neurological symptoms that mimic rett syndrome
    • DOI 10.1038/85899
    • Guy J, Hendrich B, Holmes M, Martin JE, Bird A (2001) A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 27:322-326 (Pubitemid 32201856)
    • (2001) Nature Genetics , vol.27 , Issue.3 , pp. 322-326
    • Guy, J.1    Hendrich, B.2    Holmes, M.3    Martin, J.E.4    Bird, A.5
  • 93
    • 33646145602 scopus 로고    scopus 로고
    • Lessons from fragile X regarding neurobiology, autism, and neurodegeneration
    • Hagerman RJ (2006) Lessons from fragile X regarding neurobiology, autism, and neurodegeneration. J Dev Behav Pediatr 27:63-74
    • (2006) J Dev Behav Pediatr , vol.27 , pp. 63-74
    • Hagerman, R.J.1
  • 97
    • 67651042530 scopus 로고    scopus 로고
    • A preliminary longitudinal magnetic resonance imaging study of brain volume and cortical thickness in autism
    • Hardan AY, Libove RA, Keshavan MS, Melhem NM, Minsew NJ (2009) A preliminary longitudinal magnetic resonance imaging study of brain volume and cortical thickness in autism. Biol Psychiatry 66:320-326
    • (2009) Biol Psychiatry , vol.66 , pp. 320-326
    • Hardan, A.Y.1    Libove, R.A.2    Keshavan, M.S.3    Melhem, N.M.4    Minsew, N.J.5
  • 98
    • 28544442720 scopus 로고    scopus 로고
    • Magnetic resonance imaging and head circumference study of brain size in autism: Birth through age 2 years
    • DOI 10.1001/archpsyc.62.12.1366
    • Hazlett HC, Poe M, Gerig G, Smith RG, Provenzale J, Ross A, Gilmore J, Piven J (2005) Magnetic resonance imaging and head circumference study of brain size in autism: birth through age 2 years. Arch Gen Psychiatry 62:1366-1376 (Pubitemid 41746614)
    • (2005) Archives of General Psychiatry , vol.62 , Issue.12 , pp. 1366-1376
    • Hazlett, H.C.1    Poe, M.2    Gerig, G.3    Smith, R.G.4    Provenzale, J.5    Ross, A.6    Gilmore, J.7    Piven, J.8
  • 99
    • 79960574244 scopus 로고    scopus 로고
    • Aberrant immune responses in a mouse with behavioural disorders
    • Heo Y, Zhang Y, Gao D, Miller VM, Lawrence DA (2011) Aberrant immune responses in a mouse with behavioural disorders. PLoS One 6:e20912
    • (2011) PLoS One , vol.6
    • Heo, Y.1    Zhang, Y.2    Gao, D.3    Miller, V.M.4    Lawrence, D.A.5
  • 101
    • 0034954911 scopus 로고    scopus 로고
    • Regional magnetic resonance spectroscopy of the brain in autistic individuals
    • DOI 10.1007/s002340000520
    • Hisaoka S, Harada M, Nishitani H, Mori K (2001) Regional magnetic resonance spectroscopy of the brain in autistic individuals. Neuroradiology 43:496-498 (Pubitemid 32591078)
    • (2001) Neuroradiology , vol.43 , Issue.6 , pp. 496-498
    • Hisaoka, S.1    Harada, M.2    Nishitani, H.3    Mori, K.4
  • 105
    • 0023922296 scopus 로고
    • The cerebral metabolic landscape in autism. Intercorrelations of regional glucose utilization
    • Horwitz B, Rumsey JM, Grady CL, Rapoport SI (1988) The cerebral metabolic landscape in autism. Intercorrelations of regional glucose utilization. Arch Neurol 45:749-755
    • (1988) Arch Neurol , vol.45 , pp. 749-755
    • Horwitz, B.1    Rumsey, J.M.2    Grady, C.L.3    Rapoport, S.I.4
  • 106
    • 47549099793 scopus 로고    scopus 로고
    • Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: From autism to altruism with some notes in between
    • DOI 10.1016/S0079-6123(08)00434-2, PII S0079612308004342, Advances in Vasopressin and Oxytocin - From Genes to Behaviour to Disease
    • Israel S, Lerer E, Shalev I, Uzefovsky F, Reibold M, Bachner-Melman R, Granot R, Bornstein G, Knafo A, Yirmiya N, Ebstein RP (2008) Molecular genetic studies if the arginine vaspressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between. Prog Brain Res 170:435-449 (Pubitemid 352010246)
    • (2008) Progress in Brain Research , vol.170 , pp. 435-449
    • Israel, S.1    Lerer, E.2    Shalev, I.3    Uzefovsky, F.4    Reibold, M.5    Bachner-Melman, R.6    Granot, R.7    Bornstein, G.8    Knafo, A.9    Yirmiya, N.10    Ebstein, R.P.11
  • 109
    • 84896698942 scopus 로고    scopus 로고
    • Autism and autism spectrum disorders: Clinical overview
    • Powell CM, Monteggia LM (ed) Oxford University Press, New York
    • Joseph L, Spence S, Thurm A (2013) Autism and autism spectrum disorders: clinical overview. In: Powell CM, Monteggia LM (ed) The autisms. Oxford University Press, New York, p 8
    • (2013) The Autisms , pp. 8
    • Joseph, L.1    Spence, S.2    Thurm, A.3
  • 110
    • 4043138783 scopus 로고    scopus 로고
    • Cortical activation and synchronization during sentence comprehension in high-functioning autism: Evidence of underconnectivity
    • DOI 10.1093/brain/awh199
    • Just MA, Cherkassky VL, Keller TA, Minshew NJ (2004) Cortical activation and synchronization during sentence comprehension in high-functioning autism: evidence of underconnectivity. Brain 127:1811-1821 (Pubitemid 39061557)
    • (2004) Brain , vol.127 , Issue.8 , pp. 1811-1821
    • Just, M.A.1    Cherkassky, V.L.2    Keller, T.A.3    Minshew, N.J.4
  • 111
    • 33846923678 scopus 로고    scopus 로고
    • Functional and anatomical cortical underconnectivity in autism: Evidence from an fmri study of an executive function task and corpus callosum morphometry
    • DOI 10.1093/cercor/bhl006
    • Just MA, Cherkassky VL, Keller TA, Kana RK, Minshew NJ (2007) Functional and anatomical cortical underconnectivity in autism: evidence from FMRI study of an executive functional task and corpus callosum morphometry. Cereb Cortex 17:951-961 (Pubitemid 46434636)
    • (2007) Cerebral Cortex , vol.17 , Issue.4 , pp. 951-961
    • Just, M.A.1    Cherkassky, V.L.2    Keller, T.A.3    Kana, R.K.4    Minshew, N.J.5
  • 112
    • 0036122464 scopus 로고    scopus 로고
    • Behavioral and magnetic resonance spectroscopic studies in the rat hyperserotonemic model of autism
    • DOI 10.1016/S0031-9384(01)00673-4, PII S0031938401006734
    • Kahne D, Tudorica A, Borella A, Shapiro L, Johnstone F, Huang W, Whitaker-Azmitia PM (2002) Behavioral and magnetic resonance spectroscopic studies in the rat hyperserotonemic model of autism. Physiol Behav 75:403-410 (Pubitemid 34230610)
    • (2002) Physiology and Behavior , vol.75 , Issue.3 , pp. 403-410
    • Kahne, D.1    Tudorica, A.2    Borella, A.3    Shapiro, L.4    Johnstone, F.5    Huang, W.6    Whitaker-Azmitia, P.M.7
  • 113
    • 72449207509 scopus 로고    scopus 로고
    • Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes
    • Kalueff AV, Olivier JD, Nonkes LJ, Homberg JR (2010) Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes. Neurosci Biobehav Rev 34:373-386
    • (2010) Neurosci Biobehav Rev , vol.34 , pp. 373-386
    • Kalueff, A.V.1    Olivier, J.D.2    Nonkes, L.J.3    Homberg, J.R.4
  • 114
    • 0000984981 scopus 로고
    • Autistic disturbances of affective contact
    • Kanner L (1943) Autistic disturbances of affective contact. Nerv Child 2:217-250
    • (1943) Nerv Child , vol.2 , pp. 217-250
    • Kanner, L.1
  • 115
    • 0015038274 scopus 로고
    • Follow up study of eleven autistic children originally reported in 1943
    • Kanner L (1971) Follow up study of eleven autistic children originally reported in 1943. J Autism Dev Disord 1:119-145
    • (1971) J Autism Dev Disord , vol.1 , pp. 119-145
    • Kanner, L.1
  • 116
    • 84871490248 scopus 로고    scopus 로고
    • Autism-like bahaviors with transient histone hyperacetylation in mice treated prenatally with valproic acid
    • Kataoka S, Takuma K, Hara Y, Maeda Y, Ago Y, Matsuda T (2013) Autism-like bahaviors with transient histone hyperacetylation in mice treated prenatally with valproic acid. Int J Neuropsychopharmacol 16:91-103
    • (2013) Int J Neuropsychopharmacol , vol.16 , pp. 91-103
    • Kataoka, S.1    Takuma, K.2    Hara, Y.3    Maeda, Y.4    Ago, Y.5    Matsuda, T.6
  • 118
    • 33846642070 scopus 로고    scopus 로고
    • A developmental study of the structural integrity of white matter in autism
    • DOI 10.1097/01.wnr.0000239965.21685.99, PII 0000175620070108000005
    • Keller TA, Kana RK, Just MA (2007) A developmental study of the structural integrity of white matter in autism. Neuroreport 18:23-27 (Pubitemid 46183384)
    • (2007) NeuroReport , vol.18 , Issue.1 , pp. 23-27
    • Keller, T.A.1    Kana, R.K.2    Just, M.A.3
  • 119
    • 0027532518 scopus 로고
    • The contribution of neuropathologic studies to the understanding of autism
    • Kemper TL, Bauman ML (1993) The contribution of neuropathologic studies to the understanding of autism. Neurol Clin 11:175-187 (Pubitemid 23063094)
    • (1993) Neurologic Clinics , vol.11 , Issue.1 , pp. 175-187
    • Kemper, T.L.1    Bauman, M.L.2
  • 120
    • 38749111465 scopus 로고    scopus 로고
    • The intrinsic functional organization of the rain is altered in autism
    • Kennedy DP, Courchesne E (2008) The intrinsic functional organization of the rain is altered in autism. NeuroImage 39:1877-1885
    • (2008) NeuroImage , vol.39 , pp. 1877-1885
    • Kennedy, D.P.1    Courchesne, E.2
  • 121
    • 0031052970 scopus 로고    scopus 로고
    • GKAP, a novel synaptic protein that interacts with the guanylate kinase- like domain of the PSD-95/SAP90 family of channel clustering molecules
    • DOI 10.1083/jcb.136.3.669
    • Kim E, Naisbitt S, Hsueh YP, Rao A, Rothschild A, Craig AM, Sheng M (1997) GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules. J Cell Biol 136:669-678 (Pubitemid 27083767)
    • (1997) Journal of Cell Biology , vol.136 , Issue.3 , pp. 669-678
    • Kim, E.1    Naisbitt, S.2    Hsueh, Y.-P.3    Rao, A.4    Rothschild, A.5    Craig, A.M.6    Sheng, M.7
  • 124
    • 0029006747 scopus 로고
    • Preliminary evidence for neurodegenerative changes in the substantia nigra of Rett syndrome
    • Kitt CA, Wilcox BJ (1995) Preliminary evidence for neurodegenerative changes in the substantia nigra of Rett syndrome. Neuropediatrics 26:114-118
    • (1995) Neuropediatrics , vol.26 , pp. 114-118
    • Kitt, C.A.1    Wilcox, B.J.2
  • 125
    • 80054106206 scopus 로고    scopus 로고
    • Lasting effects of chronic fluoxetine treatment on the late developing rat brain: Age-dependent changes in the serotonergic neurotransmitter system assessed by pharmacological MRI
    • Klomp A, Tremoleda JL, Wylezinska M, Nederveen AJ, Feenstra M, Gsell W, Reneman L (2012) Lasting effects of chronic fluoxetine treatment on the late developing rat brain: age-dependent changes in the serotonergic neurotransmitter system assessed by pharmacological MRI. NeuroImage 59:218-226
    • (2012) NeuroImage , vol.59 , pp. 218-226
    • Klomp, A.1    Tremoleda, J.L.2    Wylezinska, M.3    Nederveen, A.J.4    Feenstra, M.5    Gsell, W.6    Reneman, L.7
  • 127
    • 76249121818 scopus 로고    scopus 로고
    • Prenetal exposure to valproic acid leads to reduced expression of synaptic adhesion molecule neuroligin 3 in mice
    • Kolozsi E, Mackenzie RN, Roullet FI, Decatanzaro D, Foster JA (2009) Prenetal exposure to valproic acid leads to reduced expression of synaptic adhesion molecule neuroligin 3 in mice. Neuroscience 163:1201-1210
    • (2009) Neuroscience , vol.163 , pp. 1201-1210
    • Kolozsi, E.1    Mackenzie, R.N.2    Roullet, F.I.3    Decatanzaro, D.4    Foster, J.A.5
  • 128
    • 45349089199 scopus 로고    scopus 로고
    • Environmental enrichment ameliorates a motor coordination deficit in a mouse model of Rett syndrome - Mecp2 gene dosage effects and BDNF expression
    • DOI 10.1111/j.1460-9568.2008.06305.x
    • Kondo M, Gray LJ, Pelka GJ, Christodoulou J, Tam PP, Hannan AJ (2008) Environmental enrichment ameliorates a motor coordination deficit in a mouse model of Rett syndrome-Mecp2 gene dosage effects and BDNF expression. Eur J Neurosci 27:3342-3350 (Pubitemid 351847324)
    • (2008) European Journal of Neuroscience , vol.27 , Issue.12 , pp. 3342-3350
    • Kondo, M.1    Gray, L.J.2    Pelka, G.J.3    Christodoulou, J.4    Tam, P.P.L.5    Hannan, A.J.6
  • 131
    • 84863445395 scopus 로고    scopus 로고
    • The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses
    • Krueger DD, Tuffy LP, Papadopoulos T, Brose N (2012) The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses. Curr Opin Neurobiol 22:412-422
    • (2012) Curr Opin Neurobiol , vol.22 , pp. 412-422
    • Krueger, D.D.1    Tuffy, L.P.2    Papadopoulos, T.3    Brose, N.4
  • 133
    • 84860367629 scopus 로고    scopus 로고
    • Longitudinal in-vivo diffusion tensor imaging for assessing brain developmental changes in BALB/cJ mice, a model of reduced sociability relevant to autism
    • Kumar M, Kim S, Pickup S, Chen R, Fairless AH, Ittyerah R, Abel T, Brodkin ES, Poptani H (2012) Longitudinal in-vivo diffusion tensor imaging for assessing brain developmental changes in BALB/cJ mice, a model of reduced sociability relevant to autism. Brain Res 1455:56-76
    • (2012) Brain Res , vol.1455 , pp. 56-76
    • Kumar, M.1    Kim, S.2    Pickup, S.3    Chen, R.4    Fairless, A.H.5    Ittyerah, R.6    Abel, T.7    Brodkin, E.S.8    Poptani, H.9
  • 140
    • 84941426833 scopus 로고    scopus 로고
    • Autism spectrum disorder: Phenotype and diagnosis
    • Moldin SO, Rubenstein JL (eds) CRC Press, Taylor and Francis Group, Boca Raton
    • Lord C, Spence S (2006) Autism spectrum disorder: phenotype and diagnosis. In: Moldin SO, Rubenstein JL (eds) Understanding autism: from basic neuroscience to treatment. CRC Press, Taylor and Francis Group, Boca Raton, pp 1-23
    • (2006) Understanding Autism: From Basic Neuroscience to Treatment , pp. 1-23
    • Lord, C.1    Spence, S.2
  • 142
    • 39149089652 scopus 로고    scopus 로고
    • Abnormal fear conditioning and amygdala processing in an animal model of autism
    • DOI 10.1038/sj.npp.1301453, PII 1301453
    • Markram K, Rinaldi T, La Mendola D, Sandi C, Markram H (2008) Abnormal fear conditioning and amygdala processing in an animal model of autism. Neuropsychopharmacology 33:901-912 (Pubitemid 351252688)
    • (2008) Neuropsychopharmacology , vol.33 , Issue.4 , pp. 901-912
    • Markram, K.1    Rinaldi, T.2    Mendola, D.L.3    Sandi, C.4    Markram, H.5
  • 143
    • 70350626873 scopus 로고    scopus 로고
    • Microduplications of 16p11.2 are associated with schizophrenia
    • McCarthy SE, Makarov V, Kirov G et al (2009) Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet 41:1223-1227
    • (2009) Nat Genet , vol.41 , pp. 1223-1227
    • McCarthy, S.E.1    Makarov, V.2    Kirov, G.3
  • 146
    • 43449130685 scopus 로고    scopus 로고
    • Evidence for Social Anxiety and Impaired Social Cognition in a Mouse Model of Fragile X Syndrome
    • DOI 10.1037/0735-7044.122.2.293, PII S0735704408600610
    • McNaughton CH, Moon J, Strawderman MS, Maclean KN, Evans J, Strupp BJ (2008) Evidence for social anxiety and impaired social cognition in a mouse model of fragile X syndrome. Behav Neurosci 122:293-300 (Pubitemid 351672321)
    • (2008) Behavioral Neuroscience , vol.122 , Issue.2 , pp. 293-300
    • McNaughton, C.H.1    Moon, J.2    Strawderman, M.S.3    Maclean, K.N.4    Evans, J.5    Strupp, B.J.6
  • 147
    • 36749015065 scopus 로고    scopus 로고
    • Multifactor dimensionality reduction-phenomics: A novel method to capture genetic heterogeneity with use of phenotypic variables
    • DOI 10.1086/522307
    • Mei H, Cuccaro ML, Martin ER (2007) Multifactor dimensionality reduction-phenomics: a novel method to capture genetic heterogeneity with use of phenotypic variable. Am J Hum Genet 81:1251-1261 (Pubitemid 350211453)
    • (2007) American Journal of Human Genetics , vol.81 , Issue.6 , pp. 1251-1261
    • Mei, H.1    Cuccaro, M.L.2    Martin, E.R.3
  • 148
    • 33646164398 scopus 로고    scopus 로고
    • Temporal shift in methyl-CpG binding protein 2 expression in a mouse model of Rett syndrome
    • Metcalf BM, Mullaney BC, Johnston MV, Blue ME (2006) Temporal shift in methyl-CpG binding protein 2 expression in a mouse model of Rett syndrome. Neuroscience 139:1449-1460
    • (2006) Neuroscience , vol.139 , pp. 1449-1460
    • Metcalf, B.M.1    Mullaney, B.C.2    Johnston, M.V.3    Blue, M.E.4
  • 149
    • 0036197452 scopus 로고    scopus 로고
    • Behavioral and neuroanatomical characterization of the Fmr1 knockout mouse
    • DOI 10.1002/hipo.10005
    • Mineur YS, Sluyter F, de Witt S, Oostra BA, Crusio WE (2002) Behavioural and neuroanatomical characterization of the FMR1 knockout mice. Hippocampus 12:39-46 (Pubitemid 34211245)
    • (2002) Hippocampus , vol.12 , Issue.1 , pp. 39-46
    • Mineur, Y.S.1    Sluyter, F.2    De Wit, S.3    Oostra, B.A.4    Crusio, W.E.5
  • 150
    • 31444443968 scopus 로고    scopus 로고
    • Social behavior deficits in the Fmr1 mutant mouse
    • DOI 10.1016/j.bbr.2005.11.004, PII S0166432805004717
    • Mineur YS, Huynh LX, Crusio WE (2006) Social behaviour deficits in the Fmr1 mutant mouse. Behav Brain Res 168:172-175 (Pubitemid 43152066)
    • (2006) Behavioural Brain Research , vol.168 , Issue.1 , pp. 172-175
    • Mineur, Y.S.1    Huynh, L.X.2    Crusio, W.E.3
  • 151
    • 77949383668 scopus 로고    scopus 로고
    • The nature of brain dysfunction in autism: Functional brain imaging studies
    • Minshew NJ, Keller TA (2010) The nature of brain dysfunction in autism: functional brain imaging studies. Curr Opin Neurol 23:124-130
    • (2010) Curr Opin Neurol , vol.23 , pp. 124-130
    • Minshew, N.J.1    Keller, T.A.2
  • 152
    • 0027337120 scopus 로고
    • 31P MRS study of autism: Evidence for undersynthesis and increased degradation of brain membranes
    • Minshew NJ, Goldstein G, Dombrowski SM, Panchalingam K, Pettegrew JW (1993) A preliminary 31P MRS study of autism: evidence for undersynthesis and increased degradation of brain membranes. Biol Psychiatry 33:762-773 (Pubitemid 23234627)
    • (1993) Biological Psychiatry , vol.33 , Issue.11-12 , pp. 762-773
    • Minshew, N.J.1    Goldstein, G.2    Dombrowski, S.M.3    Panchalingam, K.4    Pettegrew, J.W.5
  • 154
    • 70350430194 scopus 로고    scopus 로고
    • Autism spectrum disorders in genetic syndromes: Implications for diagnosis, intervention and understanding the wider autism spectrum disorder population
    • Moss J, Howlin P (2009) Autism spectrum disorders in genetic syndromes: implications for diagnosis, intervention and understanding the wider autism spectrum disorder population. J Intellect Disabil Res 53:852-873
    • (2009) J Intellect Disabil Res , vol.53 , pp. 852-873
    • Moss, J.1    Howlin, P.2
  • 159
    • 34147152838 scopus 로고    scopus 로고
    • Postnatal dietary choline supplementation alters behavior in a mouse model of Rett syndrome
    • DOI 10.1016/j.nbd.2007.02.003, PII S0969996107000459
    • Nag N, Berger-Sweeney JE (2007) Postnatal dietary choline supplementation alters behaviour in a mouse model of Rett syndrome. Neurobiol Dis 26:473-480 (Pubitemid 46561344)
    • (2007) Neurobiology of Disease , vol.26 , Issue.2 , pp. 473-480
    • Nag, N.1    Berger-Sweeney, J.E.2
  • 162
    • 0033165926 scopus 로고    scopus 로고
    • Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin
    • DOI 10.1016/S0896-6273(00)80809-0
    • Naisbitt S, Kim E, Tu JC, Xiao B, Sala C, Valtschanoff J, Weinberg RJ, Worley PF, Sheng M (1999) Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin. Neuron 23:569-582 (Pubitemid 29359927)
    • (1999) Neuron , vol.23 , Issue.3 , pp. 569-582
    • Naisbitt, S.1    Eunjoon, K.2    Tu, J.C.3    Xiao, B.4    Sala, C.5    Valtschanoff, J.6    Weinberg, R.J.7    Worley, P.F.8    Sheng, M.9
  • 163
    • 78149360411 scopus 로고    scopus 로고
    • Altered white matter fractional anisotropy and social impairment in children with autism spectrum disorder
    • Noriuchi M, Kikuchi Y, Yoshiura T, Kira R, Shigeto H, Hara T, Tobimatsu S, Kamio Y (2010) Altered white matter fractional anisotropy and social impairment in children with autism spectrum disorder. Brain Res 1362:141-149
    • (2010) Brain Res , vol.1362 , pp. 141-149
    • Noriuchi, M.1    Kikuchi, Y.2    Yoshiura, T.3    Kira, R.4    Shigeto, H.5    Hara, T.6    Tobimatsu, S.7    Kamio, Y.8
  • 164
    • 0032794318 scopus 로고    scopus 로고
    • 1H-MR spectroscopy study
    • DOI 10.1007/s002340050795
    • Otsuka H, Harada M, Mori K, Hisaoka S, Nishitani H (1999) Brain metabolites in the hippocampus-amygdala region and cerebellum in autism: an 1H-MR spectroscopy study. Neuroradiology 41:517-519 (Pubitemid 29348670)
    • (1999) Neuroradiology , vol.41 , Issue.7 , pp. 517-519
    • Otsuka, H.1    Harada, M.2    Mori, K.3    Hisaoka, S.4    Nishitani, H.5
  • 168
    • 34748889986 scopus 로고    scopus 로고
    • Social reward among juvenile mice
    • DOI 10.1111/j.1601-183X.2006.00295.x
    • Panksepp JB, Lahvis GP (2007) Social reward among juvenile mice. Genes Brain Behav 6:661-671 (Pubitemid 47476188)
    • (2007) Genes, Brain and Behavior , vol.6 , Issue.7 , pp. 661-671
    • Panksepp, J.B.1    Lahvis, G.P.2
  • 172
    • 33645080930 scopus 로고    scopus 로고
    • Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice
    • Pelka GJ, Watson CM, Radziewic T, Hayward M, Lahooti H, Christodoulou J, Tam PP (2006) Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice. Brain 129:887-898
    • (2006) Brain , vol.129 , pp. 887-898
    • Pelka, G.J.1    Watson, C.M.2    Radziewic, T.3    Hayward, M.4    Lahooti, H.5    Christodoulou, J.6    Tam, P.P.7
  • 173
    • 32644445785 scopus 로고    scopus 로고
    • Neurobiological correlates of autism: A review of recent research
    • Penn HE (2006) Neurobiological correlates of autism: a review of recent research. Child Neuropsych 12:57-79
    • (2006) Child Neuropsych , vol.12 , pp. 57-79
    • Penn, H.E.1
  • 174
    • 80051558111 scopus 로고    scopus 로고
    • Rett syndrome: Exploring the autism link
    • Percy AK (2011) Rett syndrome: exploring the autism link. Arch Neurol 68:985-989
    • (2011) Arch Neurol , vol.68 , pp. 985-989
    • Percy, A.K.1
  • 175
    • 33746314832 scopus 로고    scopus 로고
    • Searching for ways out of the autism maze: Genetic, epigenetic and environmental clues
    • DOI 10.1016/j.tins.2006.05.010, PII S0166223606001111
    • Persico AM, Bourgeron T (2006) Searching for ways out of the autism maze: genetic, epigenetic and environmental clues. Trends Neurosci 29:349-358 (Pubitemid 44108247)
    • (2006) Trends in Neurosciences , vol.29 , Issue.7 , pp. 349-358
    • Persico, A.M.1    Bourgeron, T.2
  • 178
    • 79952060043 scopus 로고    scopus 로고
    • Genetic-background modulation of core and variable autistic-like symptoms in Fmr1 knock-out mice
    • Pietropaolo S, Guilleminot A, Martin B, D 'Amato FR, Crusio WE (2011) Genetic-background modulation of core and variable autistic-like symptoms in Fmr1 knock-out mice. PLoS One 6:e17073
    • (2011) PLoS One , vol.6
    • Pietropaolo, S.1    Guilleminot, A.2    Martin, B.3    D'Amato, F.R.4    Crusio, W.E.5
  • 182
    • 84855455705 scopus 로고    scopus 로고
    • Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion
    • Power JD, Barnes KA, Snyder AZ, Schlaggar BL, Petersen SE (2012) Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. NeuroImage 59:2142-2154
    • (2012) NeuroImage , vol.59 , pp. 2142-2154
    • Power, J.D.1    Barnes, K.A.2    Snyder, A.Z.3    Schlaggar, B.L.4    Petersen, S.E.5
  • 189
    • 58149340280 scopus 로고    scopus 로고
    • Mouse models of Rett syndrome: From behavioural phenotyping to preclinical evaluation of new therapeutic approaches
    • Ricceri L, De Filippis B, Laviola G (2008) Mouse models of Rett syndrome: from behavioural phenotyping to preclinical evaluation of new therapeutic approaches. Behav Pharmacol 19:501-517
    • (2008) Behav Pharmacol , vol.19 , pp. 501-517
    • Ricceri, L.1    De Filippis, B.2    Laviola, G.3
  • 190
    • 0021960916 scopus 로고
    • Concordance for the syndrome of autism in 40 pairs of afflicted twins
    • Ritvo ER, Freeman BJ, Mason-Brothers A, Mo A, Rotvo AM (1985) Concordance for the syndrome of autism in 40 pairs of afflicted twins. Am J Psychiatry 142:74-77 (Pubitemid 15189523)
    • (1985) American Journal of Psychiatry , vol.142 , Issue.1 , pp. 74-77
    • Ritvo, E.R.1    Freeman, B.J.2    Mason-Brothers, A.3
  • 192
    • 0031104734 scopus 로고    scopus 로고
    • Linking etiologies in humans and animal models: Studies of autism
    • DOI 10.1016/S0890-6238(97)80001-U, PII S0890623896001566
    • Rodier PM, Ingram JL, Tisdale B, Croog VJ (1997) Linking etiologies in humans and animal models: studies of autism. Reprod Toxicol 11:417-422 (Pubitemid 27180653)
    • (1997) Reproductive Toxicology , vol.11 , Issue.2-3 , pp. 417-422
    • Rodier, P.M.1    Ingram, J.L.2    Tisdale, B.3    Croog, V.J.4
  • 193
  • 194
    • 85128251104 scopus 로고    scopus 로고
    • Speech delays and behavioural problems are the predominant features in individuals with developmental delays and 16p11.2 microdeletions and microduplications
    • Rosenfeld JA, Coppinger J, Bejjani BA, Girirajan S, Eichler EE, Shaffer LG, Ballif BC (2010) Speech delays and behavioural problems are the predominant features in individuals with developmental delays and 16p11.2 microdeletions and microduplications. J Neurodev Disord 2:26-38
    • (2010) J Neurodev Disord , vol.2 , pp. 26-38
    • Rosenfeld, J.A.1    Coppinger, J.2    Bejjani, B.A.3    Girirajan, S.4    Eichler, E.E.5    Shaffer, L.G.6    Ballif, B.C.7
  • 195
    • 84856596122 scopus 로고    scopus 로고
    • Minocycline treatment reverses ultrasonic vocalization production deficit in a mouse model of Fragile X syndrome
    • Rotschafer SE, Trujillo MS, Dansie LE, Ethell IM, Razak KA (2012) Minocycline treatment reverses ultrasonic vocalization production deficit in a mouse model of Fragile X syndrome. Brain Res 1439:7-14
    • (2012) Brain Res , vol.1439 , pp. 7-14
    • Rotschafer, S.E.1    Trujillo, M.S.2    Dansie, L.E.3    Ethell, I.M.4    Razak, K.A.5
  • 196
    • 77956184210 scopus 로고    scopus 로고
    • Behvioral and molecular changes in the mouse in response to prenatal exposure to the anti-epileptic drug valproic acid
    • Roullet FI, Wollaston L, Decatanzaro D, Foster JA (2010) Behvioral and molecular changes in the mouse in response to prenatal exposure to the anti-epileptic drug valproic acid. Neuroscience 170:514-522
    • (2010) Neuroscience , vol.170 , pp. 514-522
    • Roullet, F.I.1    Wollaston, L.2    Decatanzaro, D.3    Foster, J.A.4
  • 197
    • 0242291090 scopus 로고    scopus 로고
    • Model of autism: Increased ratio of excitation/inhibition in key neural systems
    • DOI 10.1034/j.1601-183X.2003.00037.x
    • Rubenstein JL, Merzenich MM (2003) Model of autism: increased ratio of excitation/inhibition in key neural systems. Genes Brain Behav 2:255-267 (Pubitemid 37345664)
    • (2003) Genes, Brain and Behavior , vol.2 , Issue.5 , pp. 255-267
    • Rubenstein, J.L.R.1    Merzenich, M.M.2
  • 198
    • 0034106439 scopus 로고    scopus 로고
    • Genetic studies of autism: From 1970s into the millennium
    • Rutter M (2000) Genetic studies of autism: from 1970s into the millennium. J Abnorm Child Psychol 28:3-14
    • (2000) J Abnorm Child Psychol , vol.28 , pp. 3-14
    • Rutter, M.1
  • 199
    • 12344320696 scopus 로고    scopus 로고
    • Incidence of autism spectrum disorders: Changes over time and their meaning
    • Rutter M (2005) Incidence of autism spectrum disorders: changes over time and their meaning. Acta Pediatr 94:2-15
    • (2005) Acta Pediatr , vol.94 , pp. 2-15
    • Rutter, M.1
  • 200
    • 84863435952 scopus 로고    scopus 로고
    • Intact and impaired executive abilities in the BTBR mouse model of autism
    • Rutz HL, Rothblat LA (2012) Intact and impaired executive abilities in the BTBR mouse model of autism. Behav Brain Res 234:33-37
    • (2012) Behav Brain Res , vol.234 , pp. 33-37
    • Rutz, H.L.1    Rothblat, L.A.2
  • 202
    • 33344465229 scopus 로고    scopus 로고
    • A mouse model system for genetic analysis of sociability: C57BL/6J versus BALB/cJ inbred mouse strains
    • DOI 10.1016/j.biopsych.2005.07.026, PII S0006322305009157
    • Sankoorikal GM, Kaercher KA, Boon CJ, Lee JK, Brodkin ES (2006) A mouse model system for genetic analysis of sociability: C57BL/6J versus BALB/cJ inbred mouse strains. Biol Psychiatry 59:415-423 (Pubitemid 43289220)
    • (2006) Biological Psychiatry , vol.59 , Issue.5 , pp. 415-423
    • Sankoorikal, G.M.V.1    Kaercher, K.A.2    Boon, C.J.3    Lee, J.K.4    Brodkin, E.S.5
  • 203
    • 84856093663 scopus 로고    scopus 로고
    • Impact of in-scanner head motion on multiple measures of functional connectivity: Relevance for studies of neurodevelopment in youth
    • Satterthwaite TD, Wolf DH, Loughead J, Ruparel K, Elliott MA, Hakonarson H, Gur RC, Gur RE (2012) Impact of in-scanner head motion on multiple measures of functional connectivity: relevance for studies of neurodevelopment in youth. NeuroImage 60:623-632
    • (2012) NeuroImage , vol.60 , pp. 623-632
    • Satterthwaite, T.D.1    Wolf, D.H.2    Loughead, J.3    Ruparel, K.4    Elliott, M.A.5    Hakonarson, H.6    Gur, R.C.7    Gur, R.E.8
  • 205
    • 52449086931 scopus 로고    scopus 로고
    • Unusual repertoire of vocalizations in the BTBR T+tf/J mouse model of autism
    • Scattoni ML, Gandhy SU, Ricceri L, Crawley JN (2008) Unusual repertoire of vocalizations in the BTBR T+tf/J mouse model of autism. PLoS One 3:e3067
    • (2008) PLoS One , vol.3
    • Scattoni, M.L.1    Gandhy, S.U.2    Ricceri, L.3    Crawley, J.N.4
  • 206
    • 79958071067 scopus 로고    scopus 로고
    • Solving the autism puzzle a few pieces at a time
    • Schaaf CP, Zoghbi HY (2011) Solving the autism puzzle a few pieces at a time. Neuron 70:806-808
    • (2011) Neuron , vol.70 , pp. 806-808
    • Schaaf, C.P.1    Zoghbi, H.Y.2
  • 208
    • 0000526929 scopus 로고
    • Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded children
    • Schain RJ, Freedman DX (1961) Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded children. J Pediatr 58:315-320
    • (1961) J Pediatr , vol.58 , pp. 315-320
    • Schain, R.J.1    Freedman, D.X.2
  • 210
    • 11144259318 scopus 로고    scopus 로고
    • Behavioral alterations in rats prenatally to valproic acid: Animal model of autism
    • DOI 10.1038/sj.npp.1300518
    • Schneider T, Przewlocki R (2005) Behavioural alterations in rats prenatally exposed to valproic acid: animal model of autism. Neuropsychopharmacology 30:80-89 (Pubitemid 40024402)
    • (2005) Neuropsychopharmacology , vol.30 , Issue.1 , pp. 80-89
    • Schneider, T.1    Przewlocki, R.2
  • 211
    • 32844457426 scopus 로고    scopus 로고
    • Environmental enrichment reverses behavioral alterations in rats prenatally exposed to valproic acid: Issues for a therapeutic approach in autism
    • DOI 10.1055/s-2006-931550, PII 1300767
    • Schneider T, Turczak J, Przewlocki R (2006) Environmental enrichment reverses behavioural alterations in rats prenatally exposed to valproic acid: issues for therapeutic approach in autism. Neuropsychopharmacology 31:36-46 (Pubitemid 43250939)
    • (2006) Neuropsychopharmacology , vol.31 , Issue.1 , pp. 36-46
    • Schneider, T.1    Turczak, J.2    Przewlocki, R.3
  • 212
    • 34447626496 scopus 로고    scopus 로고
    • Prenatal exposure to valproic acid disturbs the enkephalinergic system functioning, basal hedonic tone, and emotional responses in an animal model of autism
    • DOI 10.1007/s00213-007-0795-y
    • Schneider T, Ziolkowska B, Gieryk A, Tyminska A, Przewlocki R (2007) Prenatal exposure to valproic acid disturbs the enkephalinergic system functioning, basal hedonic tone, and emotional responses in an animal model of autism. Psychopharmacology 193:547-555 (Pubitemid 47094372)
    • (2007) Psychopharmacology , vol.193 , Issue.4 , pp. 547-555
    • Schneider, T.1    Ziolkowska, B.2    Gieryk, A.3    Tyminska, A.4    Przewlocki, R.5
  • 215
    • 79952620959 scopus 로고    scopus 로고
    • Abnormal structure or function of the amygdala is a common component of neurodevelopmental disorders
    • Schumann CM, Bauman MD, Amaral DG (2011) Abnormal structure or function of the amygdala is a common component of neurodevelopmental disorders. Neuropsychologia 49:745-759
    • (2011) Neuropsychologia , vol.49 , pp. 745-759
    • Schumann, C.M.1    Bauman, M.D.2    Amaral, D.G.3
  • 219
    • 0032914318 scopus 로고    scopus 로고
    • Monoamine oxidase: From genes to behaviour
    • Shih JC, Chen K, Ridd MJ (1999) Monoamine oxidase: from genes to behaviour. Annu Rev Neurosci 22:197-217
    • (1999) Annu Rev Neurosci , vol.22 , pp. 197-217
    • Shih, J.C.1    Chen, K.2    Ridd, M.J.3
  • 221
    • 79751518985 scopus 로고    scopus 로고
    • Tract-specific analyses of diffusion tensor imaging show wide-spread white matter compromise in autism spectrum disorder
    • Shukla DK, Keehn B, Muller R (2011) Tract-specific analyses of diffusion tensor imaging show wide-spread white matter compromise in autism spectrum disorder. J Child Psychol Psychiatry 52:286-295
    • (2011) J Child Psychol Psychiatry , vol.52 , pp. 286-295
    • Shukla, D.K.1    Keehn, B.2    Muller, R.3
  • 222
    • 85047695687 scopus 로고    scopus 로고
    • Visuospatial processing and the function of prefrontal-parietal networks in autism spectrum disorders: A functional MRI study
    • DOI 10.1176/appi.ajp.163.8.1440
    • Silk TJ, Rinehart N, Bradshaw JL, Tonge B, Egan G, O'Boyle MW, Cunnington R (2006) Visuospatial processing and the function of prefrontal-parietal networks in autism spectrum disorders: a functional MRI study. Am J Psychiatry 163:1440-1443 (Pubitemid 44464419)
    • (2006) American Journal of Psychiatry , vol.163 , Issue.8 , pp. 1440-1443
    • Silk, T.J.1    Rinehart, N.2    Bradshaw, J.L.3    Tonge, B.4    Egan, G.5    O'Boyle, M.W.6    Cunnington, R.7
  • 223
  • 227
    • 46649092318 scopus 로고    scopus 로고
    • Towards a neuroanatomy of autism: A systematic review and meta-analysis of structural magnetic resonance imaging studies
    • DOI 10.1016/j.eurpsy.2007.05.006, PII S092493380701334X
    • Stanfield AC, McIntosh AM, Spencer MD, Philip R, Gaur S, Lawrie SM (2008) Towards a neuroanatomy of autism: a systematic review and meta-analysis of structural magnetic resonance imaging studies. Eur Psychiatry 23:289-299 (Pubitemid 351938706)
    • (2008) European Psychiatry , vol.23 , Issue.4 , pp. 289-299
    • Stanfield, A.C.1    McIntosh, A.M.2    Spencer, M.D.3    Philip, R.4    Gaur, S.5    Lawrie, S.M.6
  • 228
    • 33845284211 scopus 로고    scopus 로고
    • Discrimination learning and reversal of the conditioned eyeblink reflex in a rodent model of autism
    • DOI 10.1016/j.bbr.2006.10.022, PII S016643280600581X, Animal Model for Autism
    • Stanton ME, Peloso E, Brown KL, Rodier P (2007) Discrimination learning and reversal of the conditioned eyeblink reflex in a rodent model of autism. Behav Brain Res 176:133-140 (Pubitemid 44879632)
    • (2007) Behavioural Brain Research , vol.176 , Issue.1 , pp. 133-140
    • Stanton, M.E.1    Peloso, E.2    Brown, K.L.3    Rodier, P.4
  • 229
    • 34247862140 scopus 로고    scopus 로고
    • Behavioral and anatomical abnormalities in Mecp2 mutant mice: A model for Rett syndrome
    • DOI 10.1016/j.neuroscience.2007.02.009, PII S0306452207001820
    • Stearns NA, Schaevitz LR, Bowlling H, Nag N, Berger UV, Berger-Sweeney J (2007) Behavioural and anatomical abnormalities in Mecp2 mutant mice: a model for Rett syndrome. Neuroscience 146:907-921 (Pubitemid 46694130)
    • (2007) Neuroscience , vol.146 , Issue.3 , pp. 907-921
    • Stearns, N.A.1    Schaevitz, L.R.2    Bowling, H.3    Nag, N.4    Berger, U.V.5    Berger-Sweeney, J.6
  • 230
    • 79952317258 scopus 로고    scopus 로고
    • Structural and functional magnetic resonance imaging of autism spectrum disorders
    • Stigler KA, McDonald BC, Anand A, Saykin AJ, McDougle CJ (2011) Structural and functional magnetic resonance imaging of autism spectrum disorders. Brain Res 1380:146-161
    • (2011) Brain Res , vol.1380 , pp. 146-161
    • Stigler, K.A.1    McDonald, B.C.2    Anand, A.3    Saykin, A.J.4    McDougle, C.J.5
  • 233
    • 35148858044 scopus 로고    scopus 로고
    • A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice
    • DOI 10.1126/science.1146221
    • Tabuchi K, Blundell J, Etherton MR, Hammer RE, Liu X, Powell CM, Südhof TC (2007) A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science 318:71-76 (Pubitemid 47538032)
    • (2007) Science , vol.318 , Issue.5847 , pp. 71-76
    • Tabuchi, K.1    Blundell, J.2    Etherton, M.R.3    Hammer, R.E.4    Liu, X.5    Powell, C.M.6    Sudhof, T.C.7
  • 234
    • 0022514780 scopus 로고
    • Distribution of serotonin-containing cell bodies in the brainstem of the human fetus determined with immunohistochemistry using antiserotonin serum
    • Takahashi H, Nakashima S, Ohama E, Takeda S, Ikuta F (1986) Distribution of serotonin-containing cell bodies in the brainstem of the human fetus determined with immunohistochemistry using antiserotonin serum. Brain Dev 8:355-365 (Pubitemid 16004051)
    • (1986) Brain and Development , vol.8 , Issue.4 , pp. 355-365
    • Takahashi, H.1    Nakashima, S.2    Ohama, E.3
  • 235
    • 0020414358 scopus 로고
    • Immunohistochemical demonstration of serotonin-containing nerve fibers in the cerebellum
    • Takeuchi Y, Kimura H, Sano Y (1982) Immunohistochemical demonstration of serotonin-containing nerve fibers in the cerebellum. Cell Tissue Res 226:1-12 (Pubitemid 13238361)
    • (1982) Cell and Tissue Research , vol.226 , Issue.1 , pp. 1-12
    • Takeuchi, Y.1    Kimura, H.2    Sano, Y.3
  • 236
    • 71749092054 scopus 로고    scopus 로고
    • Deciphering Rett syndrome with mouse genetics, epigenomics, and human neurons
    • Tao J, Wu H, Sun YE (2009) Deciphering Rett syndrome with mouse genetics, epigenomics, and human neurons. Int Rev Neurobiol 89:147-160
    • (2009) Int Rev Neurobiol , vol.89 , pp. 147-160
    • Tao, J.1    Wu, H.2    Sun, Y.E.3
  • 239
    • 84874355034 scopus 로고    scopus 로고
    • Functional and structural neural network characterization of serotonin transporter knockout rats
    • Van der Marel K, Homberg JR, Otte WM, Dijkhuizen RM (2013) Functional and structural neural network characterization of serotonin transporter knockout rats. PLoS One 8:e57780
    • (2013) PLoS One , vol.8
    • Van Der Marel, K.1    Homberg, J.R.2    Otte, W.M.3    Dijkhuizen, R.M.4
  • 240
    • 81155162516 scopus 로고    scopus 로고
    • The influence of head motion on intrinsic functional connectivity MRI
    • Van Dijk KR, Sabuncu MR, Buckner RL (2012) The influence of head motion on intrinsic functional connectivity MRI. NeuroImage 59:431-438
    • (2012) NeuroImage , vol.59 , pp. 431-438
    • Van Dijk, K.R.1    Sabuncu, M.R.2    Buckner, R.L.3
  • 241
    • 11144230769 scopus 로고    scopus 로고
    • Neuroglial activation and neuroinflammation in the brain of patients with autism
    • DOI 10.1002/ana.20315
    • Vargas DL, Nascimbene C, Krishnan C, Zimmerman AW, Pardo CA (2005) Neuroglial activation and neuroinflammation in the brain of patients with autism. Ann Neurol 57:67-81 (Pubitemid 40053317)
    • (2005) Annals of Neurology , vol.57 , Issue.1 , pp. 67-81
    • Vargas, D.L.1    Nascimbene, C.2    Krishnan, C.3    Zimmerman, A.W.4    Pardo, C.A.5
  • 245
    • 35648965648 scopus 로고    scopus 로고
    • Metabolic fingerprints of altered brain growth, osmoregulation and neurotransmission in a Rett syndrome model
    • Viola A, Saywell V, Villard L, Cozzone PJ, Lutz NW (2007) Metabolic fingerprints of altered brain growth, osmoregulation and neurotransmission in a Rett syndrome model. PLoS One 2:e157
    • (2007) PLoS One , vol.2
    • Viola, A.1    Saywell, V.2    Villard, L.3    Cozzone, P.J.4    Lutz, N.W.5
  • 246
    • 0037414416 scopus 로고    scopus 로고
    • Survey of 21 inbred mouse strains in two laboratories reveals that BTBR T/+ tf/tf has severely reduced hippocampal commissure and absent corpus callosum
    • DOI 10.1016/S0006-8993(03)02354-0
    • Wahlsten D, Metten P, Crabbe JC (2003) Survey of 21 inbred mouse strains in two laboratories reveals that BTBR T+tf/tf has severely reduced hippocampal commisure and absent corpus callosum. Brain Res 971:47-54 (Pubitemid 36412063)
    • (2003) Brain Research , vol.971 , Issue.1 , pp. 47-54
    • Wahlsten, D.1    Metten, P.2    Crabbe, J.C.3
  • 248
    • 44949148164 scopus 로고    scopus 로고
    • Longitudinal brain MRI study in a mouse model of Rett Syndrome and the effects of choline
    • DOI 10.1016/j.nbd.2008.03.009, PII S0969996108000697
    • Ward BC, Agarwal S, Wang K, Berger-Sweeney J, Kolodny NH (2008) Longitudinal brain MRI study in a mouse model of Rett syndrome and the effects of choline. Neurobiol Dis 31:110-119 (Pubitemid 351822558)
    • (2008) Neurobiology of Disease , vol.31 , Issue.1 , pp. 110-119
    • Ward, B.C.1    Agarwal, S.2    Wang, K.3    Berger-Sweeney, J.4    Kolodny, N.H.5
  • 249
    • 79956040296 scopus 로고    scopus 로고
    • IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation
    • Wei H, Zou H, Sheikh AM, Malik M, Dobkin C, Brown WT, Li X (2011) IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation. J Neuroinflammation 8:52
    • (2011) J Neuroinflammation , vol.8 , pp. 52
    • Wei, H.1    Zou, H.2    Sheikh, A.M.3    Malik, M.4    Dobkin, C.5    Brown, W.T.6    Li, X.7
  • 251
    • 84867409344 scopus 로고    scopus 로고
    • Alteration of brain volume in IL-6 overexpressing mice related to autism
    • Wei H, Mori S, Hua K, Li X (2012b) Alteration of brain volume in IL-6 overexpressing mice related to autism. Int J Dev Neurosci 30:554-559
    • (2012) Int J Dev Neurosci , vol.30 , pp. 554-559
    • Wei, H.1    Mori, S.2    Hua, K.3    Li, X.4
  • 254
    • 33745728424 scopus 로고    scopus 로고
    • ITGB3 shows genetic and expression interaction with SLC6A4
    • Weiss LA, Ober C, Cook EH (2006b) ITGB3 shows genetic and expression interaction with SLC6A4. Hum Genet 120:93-100
    • (2006) Hum Genet , vol.120 , pp. 93-100
    • Weiss, L.A.1    Ober, C.2    Cook, E.H.3
  • 256
    • 0029021717 scopus 로고
    • Alterations in dopaminergic function in Rett syndrome
    • Wenk GL (1995) Alterations in dopaminergic function in Rett syndrome. Neuropediatrics 26:123-125
    • (1995) Neuropediatrics , vol.26 , pp. 123-125
    • Wenk, G.L.1
  • 257
    • 0029951783 scopus 로고    scopus 로고
    • Choline acetyltransferase activity and vesamicol binding in Rett syndrome and in rats with nucleus basalis lesions
    • DOI 10.1016/0306-4522(96)00019-X
    • Wenk GL, Mobley SL (1996) Choline acetyltransferase activity and vesamicol minding in Rett syndrome and in rats with nucleus basilis lesions. Neuroscience 73:79-84 (Pubitemid 26167656)
    • (1996) Neuroscience , vol.73 , Issue.1 , pp. 79-84
    • Wenk, G.L.1    Mobley, S.L.2
  • 258
    • 78751697098 scopus 로고    scopus 로고
    • Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism
    • Wohr M, Roullet FI, Crawley JN (2011) Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism. Genes Brain Behav 10:35-43
    • (2011) Genes Brain Behav , vol.10 , pp. 35-43
    • Wohr, M.1    Roullet, F.I.2    Crawley, J.N.3
  • 260
    • 0020566454 scopus 로고
    • Stimulation of catecholamine secretion by choline
    • Wurtman RJ (1983) Stimulation of catecholamine secretion by choline. Science 222:188
    • (1983) Science , vol.222 , pp. 188
    • Wurtman, R.J.1
  • 261
    • 84901974536 scopus 로고    scopus 로고
    • Social approach behaviours are similar on conventional versus reverse lighting cycles, and in replications across cohorts, in BTBR T+tf/J, C57BL/6J, and vasopressin receptor 1B mutant mice
    • doi:10.3389/neuro.08.001.2007
    • Yang M, Scattoni ML, Zhodzishsky V, Chen T, Caldwell H, Young WS, McFarlane HG, Crawley JN (2007) Social approach behaviours are similar on conventional versus reverse lighting cycles, and in replications across cohorts, in BTBR T+tf/J, C57BL/6J, and vasopressin receptor 1B mutant mice. Front Behav Neurosci. doi:10.3389/neuro.08.001.2007
    • (2007) Front Behav Neurosci
    • Yang, M.1    Scattoni, M.L.2    Zhodzishsky, V.3    Chen, T.4    Caldwell, H.5    Young, W.S.6    McFarlane, H.G.7    Crawley, J.N.8
  • 262
    • 64849113070 scopus 로고    scopus 로고
    • Postnatal lesion evidence against a primary role for the corpus callosum in mouse sociability
    • Yang M, Clarke AM, Crawley JN (2009) Postnatal lesion evidence against a primary role for the corpus callosum in mouse sociability. Eur J Neurosci 29:1663-1677
    • (2009) Eur J Neurosci , vol.29 , pp. 1663-1677
    • Yang, M.1    Clarke, A.M.2    Crawley, J.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.