Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 14, 2012, Pages 5469-5474

  Veenstra VanderWeele, Jeremy ^a,b,c   Muller, Christopher L ^a   Iwamoto, Hideki ^a   Sauer, Jennifer E ^a   Owens, W Anthony ^d   Shah, Charisma R ^a   Cohen, Jordan ^a   Mannangatti, Padmanabhan ^d   Jessen, Tammy ^a   Thompson, Brent J ^e   Ye, Ran ^a   Kerr, Travis M ^a   Carneiro, Ana M ^a,b,c   Crawley, Jacqueline N ^f   Sanders Bush, Elaine ^a,b,c   McMahon, Douglas G ^a,b,c   Ramamoorthy, Sammanda ^d   Daws, Lynette C ^d,e   Sutcliffe, James S ^a,b,c   Blakely, Randy D ^a,b,c  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^e Mays Cancer Center at UT Health San Antonio   (United States)

^f NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Development; Monoamine; Neurotransmitter

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38; SEROTONIN; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; COMMUNICATION DISORDER; COMPULSION; CONSTRUCT VALIDITY; CONTROLLED STUDY; FACE VALIDITY; GENETIC MODEL; GENETIC RISK; HOMEOSTASIS; HYPERSEROTONEMIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SEROTONIN RELEASE; SOCIAL DISABILITY; SOCIAL INTERACTION; SYNAPSE;

ANIMALS; AUTISTIC DISORDER; DISEASE MODELS, ANIMAL; HOMEOSTASIS; MICE; RECEPTORS, SEROTONIN; SEROTONIN; SOCIAL BEHAVIOR; STEREOTYPED BEHAVIOR;

MUS; MUS MUSCULUS;

EID: 84859475819     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1112345109     Document Type: Article

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