Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 41, 2011, Pages 17076-17081

  Horev, Guy ^a   Ellegood, Jacob ^b   Lerch, Jason P ^b   Son, Young Eun E ^a   Muthuswamy, Lakshmi ^a,e   Vogel, Hannes ^c   Krieger, Abba M ^d   Buja, Andreas ^d   Henkelman, R Mark ^b   Wigler, Michael ^a   Mills, Alea A ^a  

^a Cold Spring Harbor Laboratory ^*  (United States)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

Author keywords

Brain MRI; Home cage; Stereotypic behavior; Structural variation

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTISM; BEHAVIOR; BEHAVIOR DISORDER; CHROMOSOME; CIRCADIAN RHYTHM; CLIMBING; CONTROLLED STUDY; COPY NUMBER VARIATION; GENE EXPRESSION; GROOMING; HYPOTHALAMUS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; AUTISTIC DISORDER; BEHAVIOR, ANIMAL; BRAIN; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 16; CIRCADIAN RHYTHM; DISEASE MODELS, ANIMAL; FEMALE; GENE DOSAGE; GENETIC ENGINEERING; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PHENOTYPE; PREGNANCY; TRANSCRIPTOME;

MUS; RODENTIA;

EID: 80054754473     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1114042108     Document Type: Article

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