Alterations in frontal lobe tracts and corpus callosum in young children with autism spectrum disorder

Cerebral Cortex

Volumn 20, Issue 9, 2010, Pages 2103-2113

  Kumar, Ajay ^a   Sundaram, Senthil K ^a   Sivaswamy, Lalitha ^a   Behen, Michael E ^a   Makki, Malek I ^a,b   Ager, Joel ^b   Janisse, James ^b   Chugani, Harry T ^a   Chugani, Diane C ^a,b,c  

^a WAYNE STATE UNIVERSITY   (United States)

^b CHILDREN'S HOSPITAL OF MICHIGAN   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

association fiber tracts; autism spectrum disorder; children; corpus callosum; corticospinal tract; developmental impairment; diffusion tensor imaging; frontal lobe

Indexed keywords

ARCUATE FASCICULUS; ARTICLE; AUTISM; CHILD; CINGULUM; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS CALLOSUM; DEVELOPMENTAL DISORDER; DEVELOPMENTAL IMPAIRMENT; DIFFUSION COEFFICIENT; DIFFUSION TENSOR IMAGING; FEMALE; FRACTIONAL ANISOTROPY; FRONTAL LOBE; HUMAN; INFERIOR FRONTO OCCIPITAL FASCICULUS; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; PYRAMIDAL TRACT; TRACTOGRAPHY; UNCINATE FASCICULUS;

CHILD; CHILD DEVELOPMENT DISORDERS, PERVASIVE; CHILD, PRESCHOOL; CORPUS CALLOSUM; DIFFUSION TENSOR IMAGING; FEMALE; FRONTAL LOBE; FUNCTIONAL LATERALITY; HUMANS; MALE; NERVOUS SYSTEM MALFORMATIONS; NEURAL PATHWAYS; PREDICTIVE VALUE OF TESTS; REFERENCE VALUES;

EID: 77955928632     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhp278     Document Type: Article

References (56)

1. Alexander AL, Lee JE, Lazar M, Boudos R, Dubray MB, Oakes TR, Miller JN, Lu J, Jeong EK, McMahon WM, et al. 2007. Diffusion tensor imaging of the corpus callosum in Autism. Neuroimage. 34:61-73.
2. Bachevalier J, Loveland KA. 2006. The orbitofrontal-amygdala circuit and self-regulation of social-emotional behavior in autism. Neurosci Biobehav Rev. 30:97-117.
3. Barnea-Goraly N, Kwon H, Menon V, Eliez S, Lotspeich L, Reiss AL. 2004. White matter structure in autism: preliminary evidence from diffusion tensor imaging. Biol Psychiatry. 55:323-326.
4. Baron-Cohen S, Ring HA, Wheelwright S, Bullmore ET, Brammer MJ, Simmons A, Williams SC. 1999. Social intelligence in the normal and autistic brain: an fMRI study. Eur J Neurosci. 11:1891-1898.
5. Basser PJ. 1995. Inferring microstructural features and the physiological state of tissues from diffusion-weighted images. NMR Biomed. 8:333-344.
6. Bauman M, Kemper TL. 1985. Histoanatomic observations of the brain in early infantile autism. Neurology. 35:866-874.
7. Ben Bashat D, Kronfeld-Duenias V, Zachor DA, Ekstein PM, Hendler T, Tarrasch R, Even A, Levy Y, Ben Sira L. 2007. Accelerated maturation of white matter in young children with autism: a high b value DWI study. Neuroimage. 37:40-47.
8. Berument SK, Rutter M, Lord C, Pickles A, Bailey A. 1999. Autism screening questionnaire: diagnostic validity. Br J Psychiatry. 175:444-451.
9. Bill BR, Geschwind DH. 2009. Genetic advances in autism: heterogeneity and convergence on shared pathways. Curr Opin Genet Dev. 19:271-278.
10. Carper RA, Courchesne E. 2000. Inverse correlation between frontal lobe and cerebellum sizes in children with autism. Brain. 123(Pt 4):836-844.
11. Carper RA, Courchesne E. 2005. Localized enlargement of the frontal cortex in early autism. Biol Psychiatry. 57:126-133.
12. Castelli F, Frith C, Happe F, Frith U. 2002. Autism, Asperger syndrome and brain mechanisms for the attribution of mental states to animated shapes. Brain. 125:1839-1849.
13. Catani M, Jones DK, Daly E, Embiricos N, Deeley Q, Pugliese L, Curran S, Robertson D, Murphy DG. 2008. Altered cerebellar feedback projections in Asperger syndrome. Neuroimage. 41:1184-1191.
14. Chandana SR, Behen ME, Juhasz C, Muzik O, Rothermel RD, Mangner TJ, Chakraborty PK, Chugani HT, Chugani DC. 2005. Significance of abnormalities in developmental trajectory and asymmetry of cortical serotonin synthesis in autism. Int J Dev Neurosci. 23:171-182.
15. Chandler S, Charman T, Baird G, Simonoff E, Loucas T, Meldrum D, Scott M, Pickles A. 2007. Validation of the social communication questionnaire in a population cohort of children with autism spectrum disorders. J Am Acad Child Adolesc Psychiatry. 46:1324-1332.
16. Chugani DC, Muzik O, Behen M, Rothermel R, Janisse JJ, Lee J, Chugani HT. 1999. Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children. Ann Neurol. 45:287-295.
17. Chugani DC, Muzik O, Chakraborty P, Mangner T, Chugani HT. 1998. Human brain serotonin synthesis capacity measured in vivo with alpha-[C-11]methyl-L- tryptophan. Synapse (New York. NY 28: 33-43.
18. Ding XQ, Sun Y, Kruse B, Illies T, Zeumer H, Fiehler J, Lanfermann H. 2009. Microstructural callosal abnormalities in normal-appearing brain of children with developmental delay detected with diffusion tensor imaging. Eur Radiol. 19:1537-1543.
19. Filippi CG, Lin DD, Tsiouris AJ, Watts R, Packard AM, Heier LA, Ulug AM. 2003. Diffusion-tensor MR imaging in children with developmental delay: preliminary findings. Radiology. 229:44-50.
20. Frith U. 1989. Autism: explaining the enigma. Oxford: Blackwell.
21. Gilliam J. 1995. Gilliam Autism Rating Scales. Austin, TX: Pro-Ed.
22. Goldstein G, Minshew NJ, Siegel DJ. 1994. Age differences in academic achievement in high-functioning autistic individuals. J Clin Exp Neuropsychol. 16:671-680.
23. Hazlett EA, Buchsbaum MS, Hsieh P, Haznedar MM, Platholi J, LiCalzi EM, Cartwright C, Hollander E. 2004. Regional glucose metabolism within cortical Brodmann areas in healthy individuals and autistic patients. Neuropsychobiology. 49:115-125.
24. Haznedar MM, Buchsbaum MS, Metzger M, Solimando A, Spiegel-Cohen J, Hollander E. 1997. Anterior cingulate gyrus volume and glucose metabolism in autistic disorder. Am J Psychiatry. 154:1047-1050.
25. Haznedar MM, Buchsbaum MS, Wei TC, Hof PR, Cartwright C, Bienstock CA, Hollander E. 2000. Limbic circuitry in patients with autism spectrum disorders studied with positron emission tomography and magnetic resonance imaging. Am J Psychiatry. 157:1994-2001.
26. Herbert MR, Ziegler DA, Deutsch CK, O'Brien LM, Lange N, Bakardjiev A, Hodgson J, Adrien KT, Steele S, Makris N, et al. 2003. Dissociations of cerebral cortex, subcortical and cerebral white matter volumes in autistic boys. Brain. 126:1182-1192.
27. Herbert MR, Ziegler DA, Makris N, Filipek PA, Kemper TL, Normandin JJ, Sanders HA, Kennedy DN, Caviness VS, Jr. 2004. Localization of white matter volume increase in autism and developmental language disorder. Ann Neurol. 55:530-540.
28. Just MA, Cherkassky VL, Keller TA, Kana RK, Minshew NJ. 2007. Functional and anatomical cortical underconnectivity in autism: evidence from an FMRI study of an executive function task and corpus callosum morphometry. Cereb Cortex. 17:951-961.
29. Just MA, Cherkassky VL, Keller TA, Minshew NJ. 2004. Cortical activation and synchronization during sentence comprehension in high-functioning autism: evidence of underconnectivity. Brain. 127:1811-1821.
30. Ke X, Tang T, Hong S, Hang Y, Zou B, Li H, Zhou Z, Ruan Z, Lu Z, Tao G, et al. 2009. White matter impairments in autism, evidence from voxel-based morphometry and diffusion tensor imaging. Brain Res. 1265:171-177.
31. Keller TA, Kana RK, Just MA. 2007. A developmental study of the structural integrity of white matter in autism. Neuroreport. 18:23-27.
32. Kennedy DP, Redcay E, Courchesne E. 2006. Failing to deactivate: resting functional abnormalities in autism. Proc Natl Acad Sci USA. 103:8275-8280.
33. Koshino H, Carpenter PA, Minshew NJ, Cherkassky VL, Keller TA, Just MA. 2005. Functional connectivity in an fMRI working memory task in high-functioning autism. Neuroimage. 24:810-821.
34. Lee JE, Bigler ED, Alexander AL, Lazar M, DuBray MB, Chung MK, Johnson M, Morgan J, Miller JN, McMahon WM, et al. 2007. Diffusion tensor imaging of white matter in the superior temporal gyrus and temporal stem in autism. Neurosci Lett. 424:127-132.
35. Lee JE, Chung MK, Lazar M, DuBray MB, Kim J, Bigler ED, Lainhart JE, Alexander AL. 2009. A study of diffusion tensor imaging by tissue-specific, smoothing-compensated voxel-based analysis. Neuroimage. 44:870-883.
36. Lord C, Rutter M, Le Couteur A. 1994. Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord. 24:659-685.
37. Luna B, Minshew NJ, Garver KE, Lazar NA, Thulborn KR, Eddy WF, Sweeney JA. 2002. Neocortical system abnormalities in autism: an fMRI study of spatial working memory. Neurology. 59:834-840.
38. Minshew NJ, Williams DL. 2007. The new neurobiology of autism: cortex, connectivity, and neuronal organization. Arch Neurol. 64:945-950.
39. Mori S, Crain BJ, Chacko VP, van Zijl PC. 1999. Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann Neurol. 45:265-269.
40. Mori S, Kaufmann WE, Davatzikos C, Stieltjes B, Amodei L, Fredericksen K, Pearlson GD, Melhem ER, Solaiyappan M, Raymond GV, et al. 2002. Imaging cortical association tracts in the human brain using diffusion-tensor-based axonal tracking. Magn Reson Med. 47:215-223.
41. Mori S, Wakana S, Nagae-Poetsher LM, Van Zijl PC. 2005. MRI atlas of human white matter. Amsterdam, The Netherlands: Elsevier.
42. Muller RA. 2007. The study of autism as a distributed disorder. Ment Retard Dev Disabil Res Rev. 13:85-95.
43. Nordahl CW, Dierker D, Mostafavi I, Schumann CM, Rivera SM, Amaral DG, Van Essen DC. 2007. Cortical folding abnormalities in autism revealed by surface-based morphometry. J Neurosci. 27:11725-11735.
44. Ohnishi T, Matsuda H, Hashimoto T, Kunihiro T, Nishikawa M, Uema T, Sasaki M. 2000. Abnormal regional cerebral blood flow in childhood autism. Brain. 123(Pt 9):1838-1844.
45. Perry A, Factor DC. 1989. Psychometric validity and clinical usefulness of the Vineland Adaptive Behavior Scales and the AAMD Adaptive Behavior Scale for an autistic sample. J Autism Dev Disord. 19:41-55.
46. Rippon G, Brock J, Brown C, Boucher J. 2007. Disordered connectivity in the autistic brain: challenges for the "new psychophysiology". Int J Psychophysiol. 63:164-172.
47. Rutter M, Bailey A, Lord C. 2003. Social Communication Questionnaire (SCQ). Los Angeles, CA: Western Psychological Services.
48. Salmond CH, de Haan M, Friston KJ, Gadian DG, Vargha-Khadem F. 2003. Investigating individual differences in brain abnormalities in autism. Philos Trans R Soc Lond B Biol Sci. 358:405-413.
49. Sattler JM. 2008. Assessment of Children. La Mesa, CA: Jerome M. Sattler, Publisher.
50. Shafritz KM, Dichter GS, Baranek GT, Belger A. 2008. The neural circuitry mediating shifts in behavioral response and cognitive set in autism. Biol Psychiatry. 63:974-980.
51. Smith SM, Jenkinson M, Johansen-Berg H, Rueckert D, Nichols TE, Mackay CE, Watkins KE, Ciccarelli O, Cader MZ, Matthews PM, et al. 2006. Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. Neuroimage. 31:1487-1505.
52. Sparrow SS, Balla DA, Cicchetti DV, Doll EA. 1984. Vineland Adaptive Behavior Scales. Circle Pines, MN: American Guidance Service.
53. Sundaram S, Sivaswamy L, Makki M, Behen M, Chugani H. 2008a. Absence of arcuate fasciculus in children with global developmental delay of unknown etiology: a diffusion tensor imaging study. J Pediatrics. 152:250-255.
54. Sundaram SK, Kumar A, Makki MI, Behen ME, Chugani HT, Chugani DC. 2008b. Diffusion tensor imaging of frontal lobe in autism spectrum disorder. Cereb Cortex. 18:2659-2665.
55. Thakkar KN, Polli FE, Joseph RM, Tuch DS, Hadjikhani N, Barton JJ, Manoach DS. 2008. Response monitoring, repetitive behaviour and anterior cingulate abnormalities in autism spectrum disorders (ASD). Brain. 131:2464-2478.
56. Vitalis T, Parnavelas JG. 2003. The role of serotonin in early cortical development. Dev Neurosci. 25:245-256.