Dose-dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat

Epilepsia

Volumn 50, Issue 6, 2009, Pages 1432-1441

  Frisch, Christian ^a   Hüsch, Kerstin ^a   Angenstein, Frank ^b   Kudin, Alexei ^a   Kunz, Wolfram ^a   Elger, Christian E ^a   Helmstaedter, Christoph ^a  

^a UNIVERSITY OF BONN   (Germany)

^b LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

Author keywords

Cognitive teratogenicity; MRI volumetry; Valproate; Wistar rat

Indexed keywords

VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN SIZE; BRAIN STEM; COGNITIVE DEFECT; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; EXPOSURE; FEMALE; MALE; MEMORY DISORDER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PREGNANCY; PRIORITY JOURNAL; PROGENY; RAT; TERATOGENICITY;

ABNORMALITIES, DRUG-INDUCED; AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTICONVULSANTS; BEHAVIOR, ANIMAL; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING; EXPLORATORY BEHAVIOR; FEMALE; MAGNETIC RESONANCE IMAGING; MALE; MAZE LEARNING; MEMORY DISORDERS; MOTOR ACTIVITY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; STATISTICS AS TOPIC; UTERUS; VALPROIC ACID;

EID: 66849138564     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2008.01943.x     Document Type: Article

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