Differential loss of prolyl isomerase or chaperone activity of ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis

Journal of Biological Chemistry

Volumn 289, Issue 8, 2014, Pages 4600-4625

  Cho, Kyoung In ^a   Patil, Hemangi ^a   Senda, Eugene ^a   Wang, Jessica ^a   Yi, Haiqing ^a   Qiu, Sunny ^a   Yoon, Dosuk ^a   Yu, Minzhong ^b   Orry, Andrew ^c   Peachey, Neal S ^b,d,e   Ferreira, Paulo A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c MOLSOFT LLC   (United States)

^d LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^e CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE ACTIVITY; MECHANISTIC LINK; NONOVERLAPPING; PHYSIOLOGICAL ACTIVITY; PHYSIOLOGICAL ROLES; PHYSIOLOGICAL SUBSTRATE; PROLYL ISOMERASE; UBIQUITIN-PROTEASOME SYSTEM;

PROTEINS;

PHYSIOLOGY;

CYCLOPHILIN; ISOMERASE; M OPSIN; OPSIN; PROLYL ISOMERASE; PROTEASOME; RAN BINDING PROTEIN 2; STAT3 PROTEIN; STAT5 PROTEIN; SUMO 1 PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG;

AGE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DEUBIQUITINATION; DOWN REGULATION; ELECTROPHYSIOLOGY; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SUBSTRATE; EVOKED VISUAL RESPONSE; GENE; GENETICS; HUMAN; HUMAN CELL; ISOMERIZATION; LIGHT DARK CYCLE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HOMEOSTASIS; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEINOPATHY; PROTEOMICS; RANBP2 GENE; RETINA CONE; STRESS; UBIQUITINATION;

CHAPERONE CHAPERONIN; ENZYMES; PROTEASOME; PROTEIN MISFOLDING; UBIQUITINATION;

AGING; ANIMALS; BIOCATALYSIS; DOWN-REGULATION; EVOKED POTENTIALS, VISUAL; GTPASE-ACTIVATING PROTEINS; HELA CELLS; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP A-B; HISTONE DEACETYLASES; HUMANS; MICE; MOLECULAR CHAPERONES; MUTANT PROTEINS; MUTATION; NUCLEAR PORE COMPLEX PROTEINS; OPSINS; ORGAN SPECIFICITY; PEPTIDYLPROLYL ISOMERASE; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RETINAL CONE PHOTORECEPTOR CELLS; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; STAT TRANSCRIPTION FACTORS; STRUCTURE-ACTIVITY RELATIONSHIP; UBIQUITIN;

EID: 84896700727     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.538215     Document Type: Article

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