메뉴 건너뛰기




Volumn 2, Issue 2, 2012, Pages 207-215

The Oncogene eIF4E Reprograms the Nuclear Pore Complex to Promote mRNA Export and Oncogenic Transformation

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; DDX19 PROTEIN; GLE1 PROTEIN; MESSENGER RNA; NUCLEOPORIN; NUP214 PROTEIN; RANBP1 PROTEIN; RANBP2 PROTEIN; UNCLASSIFIED DRUG;

EID: 84865803029     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2012.07.007     Document Type: Article
Times cited : (115)

References (36)
  • 1
    • 77952776550 scopus 로고    scopus 로고
    • Control of mRNA export and translation termination by inositol hexakisphosphate requires specific interaction with Gle1
    • Alcázar-Román A.R., Bolger T.A., Wente S.R. Control of mRNA export and translation termination by inositol hexakisphosphate requires specific interaction with Gle1. J. Biol. Chem. 2010, 285:16683-16692.
    • (2010) J. Biol. Chem. , vol.285 , pp. 16683-16692
    • Alcázar-Román, A.R.1    Bolger, T.A.2    Wente, S.R.3
  • 3
    • 0031562701 scopus 로고    scopus 로고
    • The nucleoporin CAN/Nup214 binds to both the cytoplasmic and the nucleoplasmic sides of the nuclear pore complex in overexpressing cells
    • Boer J.M., van Deursen J.M., Croes H.J., Fransen J.A., Grosveld G.C. The nucleoporin CAN/Nup214 binds to both the cytoplasmic and the nucleoplasmic sides of the nuclear pore complex in overexpressing cells. Exp. Cell Res. 1997, 232:182-185.
    • (1997) Exp. Cell Res. , vol.232 , pp. 182-185
    • Boer, J.M.1    van Deursen, J.M.2    Croes, H.J.3    Fransen, J.A.4    Grosveld, G.C.5
  • 4
    • 49549099576 scopus 로고    scopus 로고
    • The mRNA export factor Gle1 and inositol hexakisphosphate regulate distinct stages of translation
    • Bolger T.A., Folkmann A.W., Tran E.J., Wente S.R. The mRNA export factor Gle1 and inositol hexakisphosphate regulate distinct stages of translation. Cell 2008, 134:624-633.
    • (2008) Cell , vol.134 , pp. 624-633
    • Bolger, T.A.1    Folkmann, A.W.2    Tran, E.J.3    Wente, S.R.4
  • 5
    • 77957737145 scopus 로고    scopus 로고
    • Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?
    • Borden K.L., Culjkovic-Kraljacic B. Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?. Leuk. Lymphoma 2010, 51:1805-1815.
    • (2010) Leuk. Lymphoma , vol.51 , pp. 1805-1815
    • Borden, K.L.1    Culjkovic-Kraljacic, B.2
  • 6
    • 0035881526 scopus 로고    scopus 로고
    • PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA
    • Cohen N., Sharma M., Kentsis A., Perez J.M., Strudwick S., Borden K.L. PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA. EMBO J. 2001, 20:4547-4559.
    • (2001) EMBO J. , vol.20 , pp. 4547-4559
    • Cohen, N.1    Sharma, M.2    Kentsis, A.3    Perez, J.M.4    Strudwick, S.5    Borden, K.L.6
  • 11
    • 0037154838 scopus 로고    scopus 로고
    • Role of nucleoporin induction in releasing an mRNA nuclear export block
    • Enninga J., Levy D.E., Blobel G., Fontoura B.M. Role of nucleoporin induction in releasing an mRNA nuclear export block. Science 2002, 295:1523-1525.
    • (2002) Science , vol.295 , pp. 1523-1525
    • Enninga, J.1    Levy, D.E.2    Blobel, G.3    Fontoura, B.M.4
  • 14
    • 0035863125 scopus 로고    scopus 로고
    • Effects of poliovirus infection on nucleo-cytoplasmic trafficking and nuclear pore complex composition
    • Gustin K.E., Sarnow P. Effects of poliovirus infection on nucleo-cytoplasmic trafficking and nuclear pore complex composition. EMBO J. 2001, 20:240-249.
    • (2001) EMBO J. , vol.20 , pp. 240-249
    • Gustin, K.E.1    Sarnow, P.2
  • 16
  • 17
    • 33748657386 scopus 로고    scopus 로고
    • Nup214 is required for CRM1-dependent nuclear protein export in vivo
    • Hutten S., Kehlenbach R.H. Nup214 is required for CRM1-dependent nuclear protein export in vivo. Mol. Cell. Biol. 2006, 26:6772-6785.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 6772-6785
    • Hutten, S.1    Kehlenbach, R.H.2
  • 18
    • 33947726050 scopus 로고    scopus 로고
    • CRM1-mediated nuclear export: to the pore and beyond
    • Hutten S., Kehlenbach R.H. CRM1-mediated nuclear export: to the pore and beyond. Trends Cell Biol. 2007, 17:193-201.
    • (2007) Trends Cell Biol. , vol.17 , pp. 193-201
    • Hutten, S.1    Kehlenbach, R.H.2
  • 19
    • 0027300051 scopus 로고
    • Characterization of wild-type and Ser53 mutant eukaryotic initiation factor 4E overexpression in mammalian cells
    • Kaufman R.J., Murtha-Riel P., Pittman D.D., Davies M.V. Characterization of wild-type and Ser53 mutant eukaryotic initiation factor 4E overexpression in mammalian cells. J. Biol. Chem. 1993, 268:11902-11909.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11902-11909
    • Kaufman, R.J.1    Murtha-Riel, P.2    Pittman, D.D.3    Davies, M.V.4
  • 20
    • 0033577860 scopus 로고    scopus 로고
    • A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export
    • Kehlenbach R.H., Dickmanns A., Kehlenbach A., Guan T., Gerace L. A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export. J. Cell Biol. 1999, 145:645-657.
    • (1999) J. Cell Biol. , vol.145 , pp. 645-657
    • Kehlenbach, R.H.1    Dickmanns, A.2    Kehlenbach, A.3    Guan, T.4    Gerace, L.5
  • 21
    • 24344457631 scopus 로고    scopus 로고
    • Interaction between the shuttling mRNA export factor Gle1 and the nucleoporin hCG1: a conserved mechanism in the export of Hsp70 mRNA
    • Kendirgi F., Rexer D.J., Alcázar-Román A.R., Onishko H.M., Wente S.R. Interaction between the shuttling mRNA export factor Gle1 and the nucleoporin hCG1: a conserved mechanism in the export of Hsp70 mRNA. Mol. Biol. Cell 2005, 16:4304-4315.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4304-4315
    • Kendirgi, F.1    Rexer, D.J.2    Alcázar-Román, A.R.3    Onishko, H.M.4    Wente, S.R.5
  • 22
    • 11144220618 scopus 로고    scopus 로고
    • Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap
    • Kentsis A., Topisirovic I., Culjkovic B., Shao L., Borden K.L. Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap. Proc. Natl. Acad. Sci. USA 2004, 101:18105-18110.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 18105-18110
    • Kentsis, A.1    Topisirovic, I.2    Culjkovic, B.3    Shao, L.4    Borden, K.L.5
  • 24
    • 77950347231 scopus 로고    scopus 로고
    • Gene regulation by nucleoporins and links to cancer
    • Köhler A., Hurt E. Gene regulation by nucleoporins and links to cancer. Mol. Cell 2010, 38:6-15.
    • (2010) Mol. Cell , vol.38 , pp. 6-15
    • Köhler, A.1    Hurt, E.2
  • 25
    • 0025314596 scopus 로고
    • Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap
    • Lazaris-Karatzas A., Montine K.S., Sonenberg N. Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap. Nature 1990, 345:544-547.
    • (1990) Nature , vol.345 , pp. 544-547
    • Lazaris-Karatzas, A.1    Montine, K.S.2    Sonenberg, N.3
  • 26
    • 79956300418 scopus 로고    scopus 로고
    • The Dbp5 cycle at the nuclear pore complex during mRNA export II: nucleotide cycling and mRNP remodeling by Dbp5 are controlled by Nup159 and Gle1
    • Noble K.N., Tran E.J., Alcázar-Román A.R., Hodge C.A., Cole C.N., Wente S.R. The Dbp5 cycle at the nuclear pore complex during mRNA export II: nucleotide cycling and mRNP remodeling by Dbp5 are controlled by Nup159 and Gle1. Genes Dev. 2011, 25:1065-1077.
    • (2011) Genes Dev. , vol.25 , pp. 1065-1077
    • Noble, K.N.1    Tran, E.J.2    Alcázar-Román, A.R.3    Hodge, C.A.4    Cole, C.N.5    Wente, S.R.6
  • 27
    • 0033601233 scopus 로고    scopus 로고
    • The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1
    • Singh B.B., Patel H.H., Roepman R., Schick D., Ferreira P.A. The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1. J. Biol. Chem. 1999, 274:37370-37378.
    • (1999) J. Biol. Chem. , vol.274 , pp. 37370-37378
    • Singh, B.B.1    Patel, H.H.2    Roepman, R.3    Schick, D.4    Ferreira, P.A.5
  • 28
  • 29
    • 0344629665 scopus 로고    scopus 로고
    • Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis
    • Topisirovic I., Guzman M.L., McConnell M.J., Licht J.D., Culjkovic B., Neering S.J., Jordan C.T., Borden K.L. Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis. Mol. Cell. Biol. 2003, 23:8992-9002.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 8992-9002
    • Topisirovic, I.1    Guzman, M.L.2    McConnell, M.J.3    Licht, J.D.4    Culjkovic, B.5    Neering, S.J.6    Jordan, C.T.7    Borden, K.L.8
  • 31
  • 32
    • 84858120416 scopus 로고    scopus 로고
    • The nucleoporin-like protein NLP1 (hCG1) promotes CRM1-dependent nuclear protein export
    • Waldmann I., Spillner C., Kehlenbach R.H. The nucleoporin-like protein NLP1 (hCG1) promotes CRM1-dependent nuclear protein export. J. Cell Sci. 2012, 125:144-154.
    • (2012) J. Cell Sci. , vol.125 , pp. 144-154
    • Waldmann, I.1    Spillner, C.2    Kehlenbach, R.H.3
  • 35
    • 0033543574 scopus 로고    scopus 로고
    • GTP hydrolysis links initiation and termination of nuclear import on the nucleoporin nup358
    • Yaseen N.R., Blobel G. GTP hydrolysis links initiation and termination of nuclear import on the nucleoporin nup358. J. Biol. Chem. 1999, 274:26493-26502.
    • (1999) J. Biol. Chem. , vol.274 , pp. 26493-26502
    • Yaseen, N.R.1    Blobel, G.2
  • 36
    • 0028784117 scopus 로고
    • Role of Ser-53 phosphorylation in the activity of human translation initiation factor eIF-4E in mammalian and yeast cells
    • Zhang Y., Klein H.L., Schneider R.J. Role of Ser-53 phosphorylation in the activity of human translation initiation factor eIF-4E in mammalian and yeast cells. Gene 1995, 163:283-288.
    • (1995) Gene , vol.163 , pp. 283-288
    • Zhang, Y.1    Klein, H.L.2    Schneider, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.