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Volumn 86, Issue 3, 1996, Pages 435-444

The immunophilin FKBP12 functions as a common inhibitor of the TGFβ family type I receptors

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOPHILIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0030576525     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80116-6     Document Type: Article
Times cited : (326)

References (47)
  • 4
    • 0026778310 scopus 로고
    • Transforming growth factor-beta in disease: The dark side of tissue repair
    • Border, W.A., and Ruoslahti, E.J. (1992). Transforming growth factor-beta in disease: the dark side of tissue repair. J. Clin. Invest. 90, 1-7.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1-7
    • Border, W.A.1    Ruoslahti, E.J.2
  • 9
    • 0028597938 scopus 로고
    • Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands
    • Cardenas, M.E., Hemenway, C., Muir, R.S., Ye, R., Fiorentino, D., and Heitman, J. (1994). Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands. EMBO J. 13, 5944-5957.
    • (1994) EMBO J. , vol.13 , pp. 5944-5957
    • Cardenas, M.E.1    Hemenway, C.2    Muir, R.S.3    Ye, R.4    Fiorentino, D.5    Heitman, J.6
  • 10
    • 0026643141 scopus 로고
    • Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
    • Clipstone, N.A., and Crabtree, G.R. (1992). Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature 357, 695-697.
    • (1992) Nature , vol.357 , pp. 695-697
    • Clipstone, N.A.1    Crabtree, G.R.2
  • 11
    • 0017704635 scopus 로고
    • A graded organ culture assay for the detection of Müllerian Inhibiting Substance
    • Donahoe, P.K., Ito, Y., and Hendren, W.H., III. (1977). A graded organ culture assay for the detection of Müllerian Inhibiting Substance. J. Surg. Res. 23, 141-148.
    • (1977) J. Surg. Res. , vol.23 , pp. 141-148
    • Donahoe, P.K.1    Ito, Y.2    Hendren W.H., III.3
  • 13
    • 0027219671 scopus 로고
    • Cloning of a type I TGF-β receptor and its effect on TGF-β binding to the type II receptor
    • Ebner, R., Chen, R.-H., Shum, L., Lawler, S., Zioncheck, T.F., Lee, A., Lopez, A.R, and Derynk, R. (1993). Cloning of a type I TGF-β receptor and its effect on TGF-β binding to the type II receptor. Science 260, 1344-1348.
    • (1993) Science , vol.260 , pp. 1344-1348
    • Ebner, R.1    Chen, R.-H.2    Shum, L.3    Lawler, S.4    Zioncheck, T.F.5    Lee, A.6    Lopez, A.R.7    Derynk, R.8
  • 14
    • 0028972072 scopus 로고
    • Transforming growth factor-β (TGF-β)-induced down-regulation of cyclin A expression requires a functional TGF-β receptor complex
    • Feng, X.-H., Filvaroff, E.H., and Derynck, R. (1995). Transforming growth factor-β (TGF-β)-induced down-regulation of cyclin A expression requires a functional TGF-β receptor complex. J. Biol. Chem. 270, 24237-24245.
    • (1995) J. Biol. Chem. , vol.270 , pp. 24237-24245
    • Feng, X.-H.1    Filvaroff, E.H.2    Derynck, R.3
  • 15
    • 0027437850 scopus 로고
    • Cdi1, a human G1 and S phase protein phosphotase that associates with Cdk2
    • Gyuris, J., Golemis, E., Chertkov, H., and Brent, R. (1993). Cdi1, a human G1 and S phase protein phosphotase that associates with Cdk2. Cell 75, 791-803.
    • (1993) Cell , vol.75 , pp. 791-803
    • Gyuris, J.1    Golemis, E.2    Chertkov, H.3    Brent, R.4
  • 16
    • 0024472603 scopus 로고
    • A receptor for the immunosuppressant FK506 is a cis-trans peptidylprolyl isomerase
    • Harding, M.W., Galat, A., Uehlin, D.E., and Schreiber, S.L. (1989). A receptor for the immunosuppressant FK506 is a cis-trans peptidylprolyl isomerase. Nature 341, 758-760.
    • (1989) Nature , vol.341 , pp. 758-760
    • Harding, M.W.1    Galat, A.2    Uehlin, D.E.3    Schreiber, S.L.4
  • 17
    • 0027240959 scopus 로고
    • The developmental expression of four novel serine/threonine kinase receptors homologous to the Activin/TGF-β II receptor family
    • He, W.W., Gustafson, M.L., Hirobe, S., and Donahoe, P.K. (1993). The developmental expression of four novel serine/threonine kinase receptors homologous to the Activin/TGF-β II receptor family. Dev. Dyn. 196, 133-142.
    • (1993) Dev. Dyn. , vol.196 , pp. 133-142
    • He, W.W.1    Gustafson, M.L.2    Hirobe, S.3    Donahoe, P.K.4
  • 18
    • 0001664017 scopus 로고
    • Recherches sur la differenciation sexuelle de l'embryon de lapin
    • Jost, A. (1947). Recherches sur la differenciation sexuelle de l'embryon de lapin. Arch. Anat. Micro. Morph. Exp. 36, 271-315.
    • (1947) Arch. Anat. Micro. Morph. Exp. , vol.36 , pp. 271-315
    • Jost, A.1
  • 19
    • 0028180315 scopus 로고
    • The TGF-beta superfamily: New members, new receptors, and new genetic tests of function in different organisms
    • Kingsley, D.M. (1994). The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8, 133-146.
    • (1994) Genes Dev. , vol.8 , pp. 133-146
    • Kingsley, D.M.1
  • 21
    • 0026537831 scopus 로고
    • Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase
    • Lin, H.Y., Wang, X.-F., Ng-Eaton, E., Weinberg, R.A., and Lodish, H.F. (1992). Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase. Cell 68, 775-785.
    • (1992) Cell , vol.68 , pp. 775-785
    • Lin, H.Y.1    Wang, X.-F.2    Ng-Eaton, E.3    Weinberg, R.A.4    Lodish, H.F.5
  • 22
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • Liu, J., Farmer, J.D., Jr., Lane, W.S., Friedman, J., Weissman, I., and Schreiber, S.L. (1991). Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66, 807-815.
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer J.D., Jr.2    Lane, W.S.3    Friedman, J.4    Weissman, I.5    Schreiber, S.L.6
  • 24
    • 0021992459 scopus 로고
    • Cellular receptors for type b transforming growth factor: Ligand binding and affinity labeling in human and rodent cell lines
    • Massagué, J., and Like, B. (1985). Cellular receptors for type b transforming growth factor: ligand binding and affinity labeling in human and rodent cell lines. J. Biol. Chem. 260, 2636-2645.
    • (1985) J. Biol. Chem. , vol.260 , pp. 2636-2645
    • Massagué, J.1    Like, B.2
  • 25
    • 0028179120 scopus 로고
    • The TGF-β family and its composite receptors
    • Massagué, J., Attisano, L., and Wrana, J.L. (1994). The TGF-β family and its composite receptors. Trends Cell Biol. 4, 172-178.
    • (1994) Trends Cell Biol. , vol.4 , pp. 172-178
    • Massagué, J.1    Attisano, L.2    Wrana, J.L.3
  • 26
    • 0025905181 scopus 로고
    • Expression cloning of an activin receptor, a predicted transmembrane serine kinase
    • Mathews, L.S., and Vale, W.W. (1991). Expression cloning of an activin receptor, a predicted transmembrane serine kinase. Cell 65, 973-982.
    • (1991) Cell , vol.65 , pp. 973-982
    • Mathews, L.S.1    Vale, W.W.2
  • 27
    • 0025104027 scopus 로고
    • TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights
    • Moses, H.L., Yang, E.Y., and Pietenpol, J.A. (1990). TGF-β stimulation and inhibition of cell proliferation: new mechanistic insights. Cell 63, 245-247.
    • (1990) Cell , vol.63 , pp. 245-247
    • Moses, H.L.1    Yang, E.Y.2    Pietenpol, J.A.3
  • 28
    • 0017704543 scopus 로고
    • Programmed cell death in the Müllerian duct induced by Müllerian Inhibiting Substance
    • Price, J.M., Donahoe, P.K., and Hendren, W.H., III. (1977). Programmed cell death in the Müllerian duct induced by Müllerian Inhibiting Substance. Am. J. Anat. 149, 353-376.
    • (1977) Am. J. Anat. , vol.149 , pp. 353-376
    • Price, J.M.1    Donahoe, P.K.2    Hendren W.H., III.3
  • 29
    • 0027503601 scopus 로고
    • Physiological actions and clinical applications of transforming growth factor-β
    • Roberts, A.B., and Sporn, M.B. (1993). Physiological actions and clinical applications of transforming growth factor-β. Growth Factors 8, 1-9.
    • (1993) Growth Factors , vol.8 , pp. 1-9
    • Roberts, A.B.1    Sporn, M.B.2
  • 30
    • 0028239893 scopus 로고
    • RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
    • Sabatini, D.M., Erdjument-Bromage, J., Lui, M., Tempst, P., and Snyder, S.H. (1994). RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. Cell 78, 35-43.
    • (1994) Cell , vol.78 , pp. 35-43
    • Sabatini, D.M.1    Erdjument-Bromage, J.2    Lui, M.3    Tempst, P.4    Snyder, S.H.5
  • 31
    • 0026793456 scopus 로고
    • Growth factor signaling by receptor tyrosine kinases
    • Schlessinger, J., and Ulrich, A. (1992). Growth factor signaling by receptor tyrosine kinases. Neuron 9, 383-391.
    • (1992) Neuron , vol.9 , pp. 383-391
    • Schlessinger, J.1    Ulrich, A.2
  • 32
    • 0024442393 scopus 로고
    • A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin
    • Siekierka, J.J., Hung, S.H.Y., Poe, M., Lin, C.S., and Sigal, N.H. (1989). A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin. Nature 341, 755-777.
    • (1989) Nature , vol.341 , pp. 755-777
    • Siekierka, J.J.1    Hung, S.H.Y.2    Poe, M.3    Lin, C.S.4    Sigal, N.H.5
  • 34
    • 0027328191 scopus 로고
    • Activin receptor-like kinases: A novel subclass of cell-surface receptors with predicted serine/ threonine kinase activity
    • ten Dijke, P., Ichijo, H., Franzen, P., Schulz, P., Saras, J., Toyoshima, H., Heldin, C.H., Miyanzono, K. (1993). Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/ threonine kinase activity. Oncogene 8, 2879-2887.
    • (1993) Oncogene , vol.8 , pp. 2879-2887
    • Ten Dijke, P.1    Ichijo, H.2    Franzen, P.3    Schulz, P.4    Saras, J.5    Toyoshima, H.6    Heldin, C.H.7    Miyanzono, K.8
  • 35
    • 0028295762 scopus 로고
    • Characterization of type I receptors for transforming growth factor-β and activin
    • ten Dijke, P., Yamashita, H., Ichijo, H., Franzen, P., Laiho, M., Miyazono, K., Heldin, C.H. (1994). Characterization of type I receptors for transforming growth factor-β and activin. Science 264, 101-104.
    • (1994) Science , vol.264 , pp. 101-104
    • Dijke, P.1    Yamashita, H.2    Ichijo, H.3    Franzen, P.4    Laiho, M.5    Miyazono, K.6    Heldin, C.H.7
  • 36
    • 0020324761 scopus 로고
    • The epithelial-mesenchymal interface of the male rat mullerian duct: Loss of basement membrane integrity and ductal regression
    • Trelstad, R.L., Hayashi, A., Hayashi, K., and Donahoe, P.K. (1982). The epithelial-mesenchymal interface of the male rat mullerian duct: loss of basement membrane integrity and ductal regression. Dev. Biol. 92, 27-40.
    • (1982) Dev. Biol. , vol.92 , pp. 27-40
    • Trelstad, R.L.1    Hayashi, A.2    Hayashi, K.3    Donahoe, P.K.4
  • 37
    • 0028108801 scopus 로고
    • Specific interaction of type I receptors of the TGF-β family with the immunophilin FKBP12
    • Wang, T.W., Donahoe, P.K., and Zervos, A.S. (1994). Specific interaction of type I receptors of the TGF-β family with the immunophilin FKBP12. Science 265, 674-676.
    • (1994) Science , vol.265 , pp. 674-676
    • Wang, T.W.1    Donahoe, P.K.2    Zervos, A.S.3
  • 39
    • 0030030373 scopus 로고    scopus 로고
    • Complementation between kinase-defective and activation-defective TGF-β receptors reveals a novel form of receptor cooperativity essential for signaling
    • Weis-Garcia, F., and Massagué, J. (1996). Complementation between kinase-defective and activation-defective TGF-β receptors reveals a novel form of receptor cooperativity essential for signaling. EMBO J. 15, 276-289.
    • (1996) EMBO J. , vol.15 , pp. 276-289
    • Weis-Garcia, F.1    Massagué, J.2
  • 40
    • 0029022221 scopus 로고
    • GS domain mutations that constitutively activate TGF-βR1, the downstream signaling component in the TGF-β receptor complex
    • Wieser, R., Wrana, J.L., and Massagué, J. (1995). GS domain mutations that constitutively activate TGF-βR1, the downstream signaling component in the TGF-β receptor complex. EMBO J. 14, 2199-2208.
    • (1995) EMBO J. , vol.14 , pp. 2199-2208
    • Wieser, R.1    Wrana, J.L.2    Massagué, J.3
  • 44
    • 0028218186 scopus 로고
    • The Drosophila saxophone gene: A serine-threonine kinase receptor of the TGF-β super-family
    • Xie, T., Finelli, A.L., and Padgett, R.W. (1994). The Drosophila saxophone gene: a serine-threonine kinase receptor of the TGF-β super-family. Science 263, 1756-1759.
    • (1994) Science , vol.263 , pp. 1756-1759
    • Xie, T.1    Finelli, A.L.2    Padgett, R.W.3
  • 45
    • 0027463577 scopus 로고
    • A composite FKBP12-FK506 surface that contacts calcineurin
    • Yang, D., Rosen, M.K., and Schreiber, S.L. (1993). A composite FKBP12-FK506 surface that contacts calcineurin. J. Am. Chem. Soc. 115, 819-820.
    • (1993) J. Am. Chem. Soc. , vol.115 , pp. 819-820
    • Yang, D.1    Rosen, M.K.2    Schreiber, S.L.3
  • 46
    • 0027511606 scopus 로고
    • Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites
    • Zervos, A.S., Gyuris, J., and Brent, R. (1993). Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell 72, 223-232.
    • (1993) Cell , vol.72 , pp. 223-232
    • Zervos, A.S.1    Gyuris, J.2    Brent, R.3
  • 47
    • 0029071264 scopus 로고
    • TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin
    • Zheng, X.-F., Fiorentino, D., Chen, J., Crabtree, G.R., and Schreiber, S.L. (1995). TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin. Cell 82, 121-130.
    • (1995) Cell , vol.82 , pp. 121-130
    • Zheng, X.-F.1    Fiorentino, D.2    Chen, J.3    Crabtree, G.R.4    Schreiber, S.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.