-
1
-
-
0039115156
-
Transport into and out of the cell nucleus
-
Görlich, D. Transport into and out of the cell nucleus. EMBO J. 17, 2721-2727 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 2721-2727
-
-
Görlich, D.1
-
2
-
-
0001556063
-
A Ran-binding motif found in nuclear pore proteins
-
Hartmann, E. & Görlich, D. A Ran-binding motif found in nuclear pore proteins. Trends Cell Biol. 5, 192-193 (1995).
-
(1995)
Trends Cell Biol.
, vol.5
, pp. 192-193
-
-
Hartmann, E.1
Görlich, D.2
-
3
-
-
0029117229
-
A family of Ran binding proteins that includes nucleoporins
-
Dingwall, C., Kandels-Lewis, S. & Séraphin, B. A family of Ran binding proteins that includes nucleoporins. Proc. Natl Acad. Sci. USA 92, 7525-7529 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 7525-7529
-
-
Dingwall, C.1
Kandels-Lewis, S.2
Séraphin, B.3
-
4
-
-
0028834428
-
Protein import into nuclei - Association and dissociation reactions involving transport substrate, transport factors, and nucleoporins
-
Rexach, M. & Blobel, G. Protein import into nuclei - association and dissociation reactions involving transport substrate, transport factors, and nucleoporins. Cell 83, 683-692 (1995).
-
(1995)
Cell
, vol.83
, pp. 683-692
-
-
Rexach, M.1
Blobel, G.2
-
5
-
-
0029853631
-
Identification of different roles for RanGDP and RanGTP in nuclear protein import
-
Görlich, D., Pante, N., Kutay, U., Aebi, U. & Bischoff, F. R. Identification of different roles for RanGDP and RanGTP in nuclear protein import. EMBO J. 15, 5584-5594 (1996).
-
(1996)
EMBO J.
, vol.15
, pp. 5584-5594
-
-
Görlich, D.1
Pante, N.2
Kutay, U.3
Aebi, U.4
Bischoff, F.R.5
-
6
-
-
0030924190
-
CRMI is an export receptor for leucine-rich nuclear export signals
-
Fornerod, M., Ohno, M., Yoshida, M. & Mattaj, I. W. CRMI is an export receptor for leucine-rich nuclear export signals. Cell 90, 1051-1060 (1997).
-
(1997)
Cell
, vol.90
, pp. 1051-1060
-
-
Fornerod, M.1
Ohno, M.2
Yoshida, M.3
Mattaj, I.W.4
-
7
-
-
0029920934
-
The nucleic transport factor karyopherin-beta binds stoichiometrically to ran-GTP and inhibits the ran GTPase-activating protein
-
Floer, M. & Blobel, G. The nucleic transport factor karyopherin-beta binds stoichiometrically to ran-GTP and inhibits the ran GTPase-activating protein. J. Biol. Chem. 271, 5313-5316 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5313-5316
-
-
Floer, M.1
Blobel, G.2
-
8
-
-
0028937195
-
Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1
-
Bischoff, F. R., Krebber, H., Smirnova, E., Dong, W. & Ponstingl, H. Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1. EMBO J. 14, 705-713 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 705-713
-
-
Bischoff, F.R.1
Krebber, H.2
Smirnova, E.3
Dong, W.4
Ponstingl, H.5
-
9
-
-
0345647103
-
RanBP1 is crucial for the release of Ran-GTP from importin-β-related nuclear transport factors
-
Bischoff, F. R. & Görlich, D. RanBP1 is crucial for the release of Ran-GTP from importin-β-related nuclear transport factors. FEBS lett. 419, 249-254 (1997).
-
(1997)
FEBS Lett.
, vol.419
, pp. 249-254
-
-
Bischoff, F.R.1
Görlich, D.2
-
10
-
-
0028802811
-
Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex
-
Wilken, N., Senécal, J.-L., Scheer, U. & Dabauvalle, M.-C. Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex. Eur. J. Cell Biol. 68, 211-219 (1995).
-
(1995)
Eur. J. Cell Biol.
, vol.68
, pp. 211-219
-
-
Wilken, N.1
Senécal, J.-L.2
Scheer, U.3
Dabauvalle, M.-C.4
-
11
-
-
0030696935
-
Ran-GTP targets p97 to RanBP2, a filamentous protein localized at the cytoplasmic periphery of the nuclear pore complex
-
Delphin, C., Guan, T., Melchior, F. & Gerace, L. Ran-GTP targets p97 to RanBP2, a filamentous protein localized at the cytoplasmic periphery of the nuclear pore complex. Mol. Biol. Cell 8, 2379-2390 (1997).
-
(1997)
Mol. Biol. Cell
, vol.8
, pp. 2379-2390
-
-
Delphin, C.1
Guan, T.2
Melchior, F.3
Gerace, L.4
-
12
-
-
0029032954
-
A giant nucleopore protein that binds Ran/TC4
-
Yokoyama, N. et al. A giant nucleopore protein that binds Ran/TC4. Nature 376, 184-188 (1995).
-
(1995)
Nature
, vol.376
, pp. 184-188
-
-
Yokoyama, N.1
-
13
-
-
0029070074
-
Nup358, a cytoplasmatically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region
-
Wu, J., Matunis, M. J., Kraemer, D., Blobel, G. & Coutavas, E. Nup358, a cytoplasmatically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region. J. Biol. Chem. 270, 14209-14213 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14209-14213
-
-
Wu, J.1
Matunis, M.J.2
Kraemer, D.3
Blobel, G.4
Coutavas, E.5
-
14
-
-
0029021567
-
The peptide repeat domain of nucleoporin Nup98 functions as docking site in transport across the nuclear pore complex
-
Radu, A., Moore, M. S. & Blobel, G. The peptide repeat domain of nucleoporin Nup98 functions as docking site in transport across the nuclear pore complex. Cell 81, 215-222 (1995).
-
(1995)
Cell
, vol.81
, pp. 215-222
-
-
Radu, A.1
Moore, M.S.2
Blobel, G.3
-
15
-
-
0028832520
-
GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import
-
Melchior, F., Guan, T., Yokoyama, N., Nishimoto, T. & Gerace, L. GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import. J. Cell Biol. 131, 571-581 (1995).
-
(1995)
J. Cell Biol.
, vol.131
, pp. 571-581
-
-
Melchior, F.1
Guan, T.2
Yokoyama, N.3
Nishimoto, T.4
Gerace, L.5
-
16
-
-
0032080831
-
Two-way trafficking with Ran
-
Melchior, F. & Gerace, L. Two-way trafficking with Ran. Trends Cell Biol. 8, 175-179 (1998).
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 175-179
-
-
Melchior, F.1
Gerace, L.2
-
17
-
-
0028929866
-
Crystal structure of human Ran complexed with GDP
-
Scheffzek, K., Klebe, C., Fritz-Wolf, K., Kabsch, W. & Wittinghofer, A. Crystal structure of human Ran complexed with GDP. Nature 374, 378-381 (1995).
-
(1995)
Nature
, vol.374
, pp. 378-381
-
-
Scheffzek, K.1
Klebe, C.2
Fritz-Wolf, K.3
Kabsch, W.4
Wittinghofer, A.5
-
18
-
-
0028556994
-
Structure of the human ADP-ribosylation factor I complexed with GDP
-
Amor, J. C. et al. Structure of the human ADP-ribosylation factor I complexed with GDP. Nature 372, 704-708 (1994).
-
(1994)
Nature
, vol.372
, pp. 704-708
-
-
Amor, J.C.1
-
19
-
-
0029113233
-
The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms
-
Greasley, S. E. et al. The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms. Nature Struct. Biol. 2, 797-806 (1995).
-
(1995)
Nature Struct. Biol.
, vol.2
, pp. 797-806
-
-
Greasley, S.E.1
-
20
-
-
0030587932
-
An alpha to beta conformational switch in EF-TU
-
Abel, K., Yoder, M. D., Hilgenfeld, R. & Jurnak, F. An alpha to beta conformational switch in EF-TU. Structure 4, 1153-1159 (1996).
-
(1996)
Structure
, vol.4
, pp. 1153-1159
-
-
Abel, K.1
Yoder, M.D.2
Hilgenfeld, R.3
Jurnak, F.4
-
21
-
-
0030587857
-
Helix unwinding in the effector of elongation factor EF-TU-GDP
-
Polekhina, G. et al. Helix unwinding in the effector of elongation factor EF-TU-GDP. Structure 4, 1141-1151 (1996).
-
(1996)
Structure
, vol.4
, pp. 1141-1151
-
-
Polekhina, G.1
-
22
-
-
0025740753
-
The structure of Ras protein: A model for a universal molecular switch
-
Wittinghofer, A. & Pai, E. F. The structure of Ras protein: a model for a universal molecular switch. Trends Biochem. Sci. 16, 382-387 (1991).
-
(1991)
Trends Biochem. Sci.
, vol.16
, pp. 382-387
-
-
Wittinghofer, A.1
Pai, E.F.2
-
23
-
-
0032538317
-
Structural basis for activation of ARF GTPase: Mechanisms of guanine nucleotide exchange and GTP-myristoyl switching
-
Goldberg, J. Structural basis for activation of ARF GTPase: Mechanisms of guanine nucleotide exchange and GTP-myristoyl switching. Cell 95, 237-248 (1998).
-
(1998)
Cell
, vol.95
, pp. 237-248
-
-
Goldberg, J.1
-
24
-
-
0029026774
-
The C terminus of the nuclear RAN/TC4 GTPase stabilizes the GDP-bound state and mediates interactions with RCC1, RAN-GAP, and HTF9A/ RANBP1
-
Richards, S. A., Lounsbury, K. M. & Macara, I. The C terminus of the nuclear RAN/TC4 GTPase stabilizes the GDP-bound state and mediates interactions with RCC1, RAN-GAP, and HTF9A/ RANBP1. J. Biol. Chem. 270, 14405-14411 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14405-14411
-
-
Richards, S.A.1
Lounsbury, K.M.2
Macara, I.3
-
25
-
-
0028964821
-
Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1
-
Klebe, C., Bischoff, F. R., Ponstingl, H. & Wittinghofer, A. Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1. Biochemistry 34, 639-647 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 639-647
-
-
Klebe, C.1
Bischoff, F.R.2
Ponstingl, H.3
Wittinghofer, A.4
-
26
-
-
0032538803
-
NTF2 mediates nuclear import of Ran
-
Ribbeck, K., Lipowsky, G., Kent, H. M., Stewart, M. & Görlich, D. NTF2 mediates nuclear import of Ran. EMBO J. 17, 6587-6598 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 6587-6598
-
-
Ribbeck, K.1
Lipowsky, G.2
Kent, H.M.3
Stewart, M.4
Görlich, D.5
-
27
-
-
0032478537
-
Structural basis for molecular recognition between nuclear transport factor 2 (NFT2) and GTP-bound form of the Ras family GTPase Ran
-
Stewart, M., Kent, H. M. & Mccoy, A. J. Structural basis for molecular recognition between nuclear transport factor 2 (NFT2) and GTP-bound form of the Ras family GTPase Ran. J. Mol. Biol. 277, 535-646 (1998).
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 535-646
-
-
Stewart, M.1
Kent, H.M.2
McCoy, A.J.3
-
28
-
-
0028955712
-
The Ran/TC4 GTPase-binding domain: Identification by expression cloning and characterization of a conserved sequence motif
-
Beddow, A. L., Richards, S. A., Orem, N. R. & Macara, I. G. The Ran/TC4 GTPase-binding domain: Identification by expression cloning and characterization of a conserved sequence motif. Proc. Natl Acad. Sci. USA 92, 3328-3332 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 3328-3332
-
-
Beddow, A.L.1
Richards, S.A.2
Orem, N.R.3
Macara, I.G.4
-
30
-
-
0039710379
-
Structure of the PH domain and BTK motif from Bruton's tyrosine kinase: Molecular explanations for X-linked agammaglobulinzemia
-
Hyvönen, M. & Saraste, M. Structure of the PH domain and BTK motif from Bruton's tyrosine kinase: Molecular explanations for X-linked agammaglobulinzemia. EMBO J. 16, 3396-3404 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 3396-3404
-
-
Hyvönen, M.1
Saraste, M.2
-
31
-
-
0028246440
-
Binding of G protein βγ-subunits to pleckstrin homology domains
-
Touhara, K., Inglese, J., Pitcher, J. A., Shaw, G. & Lefkowitz, R. J. Binding of G protein βγ-subunits to pleckstrin homology domains. J. Biol. Chem. 269, 10217-10220 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 10217-10220
-
-
Touhara, K.1
Inglese, J.2
Pitcher, J.A.3
Shaw, G.4
Lefkowitz, R.J.5
-
32
-
-
0028784164
-
Mutants in a yeast Ran binding protein are defective in nuclear transport
-
Schlenstedt, G., Wong, D. H., Koepp, D. M. & Silver, P. A. Mutants in a yeast Ran binding protein are defective in nuclear transport. EMBO J. 14, 5367-5378 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 5367-5378
-
-
Schlenstedt, G.1
Wong, D.H.2
Koepp, D.M.3
Silver, P.A.4
-
33
-
-
0000538815
-
Analytical molecular surface calculation
-
Connolly, M. L. Analytical molecular surface calculation. J. Appl. Crystallogr. 16, 548-558 (1983).
-
(1983)
J. Appl. Crystallogr.
, vol.16
, pp. 548-558
-
-
Connolly, M.L.1
-
34
-
-
0030870158
-
Dynamic and equilibrium studies on the interaction of Ran with its effector RanBP1.
-
Kuhlmann, J., Macara, I. & Wittinghofer, A. Dynamic and equilibrium studies on the interaction of Ran with its effector RanBP1. Biochemistry 36, 12027-12035 (1997).
-
(1997)
Biochemistry
, vol.36
, pp. 12027-12035
-
-
Kuhlmann, J.1
Macara, I.2
Wittinghofer, A.3
-
35
-
-
0029617615
-
Structure of the high affinity complex of inositol triphosphale with a phospholipase C pleckstrin homology domain
-
Ferguson, K. M., Lemmon, M. A., Schlessinger, J. & Sigler, P. B. Structure of the high affinity complex of inositol triphosphale with a phospholipase C pleckstrin homology domain. Cell 83, 1037-1046 (1995).
-
(1995)
Cell
, vol.83
, pp. 1037-1046
-
-
Ferguson, K.M.1
Lemmon, M.A.2
Schlessinger, J.3
Sigler, P.B.4
-
36
-
-
0029096888
-
Structure of the binding site for inositol phosphates in a PH domain
-
Hyvönen, M. et al. Structure of the binding site for inositol phosphates in a PH domain. EMBO J. 14, 4676-4685 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 4676-4685
-
-
Hyvönen, M.1
-
38
-
-
0029107760
-
The 2.2 Ȧ crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue
-
Nassar, N. et al. The 2.2 Ȧ crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue. Nature 375, 554-560 (1995).
-
(1995)
Nature
, vol.375
, pp. 554-560
-
-
Nassar, N.1
-
39
-
-
0030462224
-
Mutations within the Ran/TC4 GTPase-effects on regulatory factor interactions and subcellular localization
-
Lounsbury, K. M., Richards, S. A., Carey, K. L. & Macara, I. G. Mutations within the Ran/TC4 GTPase-effects on regulatory factor interactions and subcellular localization. J. Biol. Chem. 271, 32834-32841 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32834-32841
-
-
Lounsbury, K.M.1
Richards, S.A.2
Carey, K.L.3
Macara, I.G.4
-
40
-
-
0030772378
-
The Ras-RasGAP complex: Structural basis for GTPase activation and its loss in oncogenic Ras mutants
-
Scheffzek, K. et al. The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science 277, 333-338 (1998).
-
(1998)
Science
, vol.277
, pp. 333-338
-
-
Scheffzek, K.1
-
41
-
-
0029847386
-
RanBP1 stabilizes the interaction of Ran with p97 in nuclear protein import
-
Chi, N. C., Adam, E. J. H., Visser, G. D. & Adam, S. A. RanBP1 stabilizes the interaction of Ran with p97 in nuclear protein import. J. Cell. Biol. 135, 559-569 (1996).
-
(1996)
J. Cell. Biol.
, vol.135
, pp. 559-569
-
-
Chi, N.C.1
Adam, E.J.H.2
Visser, G.D.3
Adam, S.A.4
-
42
-
-
0027879008
-
Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell contents
-
Kabsch, W. Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell contents. J. Appl. Crystallogr. 26, 795-800 (1993).
-
(1993)
J. Appl. Crystallogr.
, vol.26
, pp. 795-800
-
-
Kabsch, W.1
-
43
-
-
0028103275
-
Collaborative computational project no. 4. The CCP4 suite: Programs for protein crystallography
-
Collaborative Computational Project No. 4. The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D 50, 760-763 (1994).
-
(1994)
Acta Crystallogr. D
, vol.50
, pp. 760-763
-
-
-
44
-
-
0030841587
-
Electron-density map interpretation
-
Jones, T. A. & Kjeldgaard, M. Electron-density map interpretation. Methods Enzymol. 277, 173-208 (1997).
-
(1997)
Methods Enzymol.
, vol.277
, pp. 173-208
-
-
Jones, T.A.1
Kjeldgaard, M.2
-
45
-
-
3543012707
-
Crystallography and NMR system: A new software system for macromolecular structure determination
-
Brunger, A. T. et al. Crystallography and NMR system: A new software system for macromolecular structure determination. Acta Crystallogr. C 54, 905-921 (1998).
-
(1998)
Acta Crystallogr. C
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
-
46
-
-
0030729838
-
An extensively modified version of MOLSCRIPT that includes greatly enhanced coloring capabilities
-
Esnouf, R. M. An extensively modified version of MOLSCRIPT that includes greatly enhanced coloring capabilities. J. Mol. Graphics 15, 132-134 (1997).
-
(1997)
J. Mol. Graphics
, vol.15
, pp. 132-134
-
-
Esnouf, R.M.1
-
47
-
-
0025310575
-
Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 Ȧ resolution: Implications for the mechanism of GTP hydrolysis
-
Pai, E. F. et al. Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 Ȧ resolution: implications for the mechanism of GTP hydrolysis. EMBO J. 9, 2351-2359 (1990).
-
(1990)
EMBO J.
, vol.9
, pp. 2351-2359
-
-
Pai, E.F.1
-
48
-
-
0026244229
-
MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
-
Kraulis, P. J. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24, 946-950 (1991).
-
(1991)
J. Appl. Crystallogr.
, vol.24
, pp. 946-950
-
-
Kraulis, P.J.1
-
49
-
-
0028057108
-
Raster3D version 2.0. A program for photorealistic molecular graphics
-
Merritt, E. A. & Murphy, M. E. P. Raster3D version 2.0. A program for photorealistic molecular graphics. Acta Crystallogr. D 50, 869-873 (1994).
-
(1994)
Acta Crystallogr. D
, vol.50
, pp. 869-873
-
-
Merritt, E.A.1
Murphy, M.E.P.2
-
50
-
-
0026319199
-
Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
-
Nicholls, A., Sharp, K. A. & Honig, B. Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins 11, 281-296 (1991).
-
(1991)
Proteins
, vol.11
, pp. 281-296
-
-
Nicholls, A.1
Sharp, K.A.2
Honig, B.3
|