-
1
-
-
78149409465
-
Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease
-
J. Ren, L. Pulakat, A. Whaley-Connell, and J.R. Sowers Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease J. Mol. Med. 88 2010 993 1001
-
(2010)
J. Mol. Med.
, vol.88
, pp. 993-1001
-
-
Ren, J.1
Pulakat, L.2
Whaley-Connell, A.3
Sowers, J.R.4
-
2
-
-
53649083550
-
Is mitochondrial dysfunction a cause of insulin resistance?
-
N. Turner, and L.K. Heilbronn Is mitochondrial dysfunction a cause of insulin resistance? Trends Endocrinol. Metab. 19 2008 324 330
-
(2008)
Trends Endocrinol. Metab.
, vol.19
, pp. 324-330
-
-
Turner, N.1
Heilbronn, L.K.2
-
3
-
-
71849083948
-
Abnormal mitochondrial dynamics and neurodegenerative diseases
-
B. Su, X. Wang, L. Zheng, G. Perry, M.A. Smith, and X. Zhu Abnormal mitochondrial dynamics and neurodegenerative diseases Biochim. Biophys. Acta 1802 2010 135 142
-
(2010)
Biochim. Biophys. Acta
, vol.1802
, pp. 135-142
-
-
Su, B.1
Wang, X.2
Zheng, L.3
Perry, G.4
Smith, M.A.5
Zhu, X.6
-
4
-
-
77956189388
-
Signaling pathways in mitochondrial dysfunction and aging
-
C. Mammucari, and R. Rizzuto Signaling pathways in mitochondrial dysfunction and aging Mech. Ageing Dev. 131 2010 536 543
-
(2010)
Mech. Ageing Dev.
, vol.131
, pp. 536-543
-
-
Mammucari, C.1
Rizzuto, R.2
-
5
-
-
83055173304
-
The first identification of lysine malonylation substrates and its regulatory enzyme
-
10.1074/mcp.M1111.012658
-
C. Peng, Z. Lu, Z. Xie, Z. Cheng, Y. Chen, M. Tan, H. Luo, Y. Zhang, W. He, K. Yang, B.M.M. Zwaans, D. Tishkoff, L. Ho, D. Lombard, T.-C. He, J. Dai, E. Verdin, Y. Ye, and Y. Zhao The First Identification of Lysine Malonylation Substrates and Its Regulatory Enzyme Mol. Cell. Proteomics 10 2011 10.1074/mcp.M1111.012658
-
(2011)
Mol. Cell. Proteomics
, vol.10
-
-
Peng, C.1
Lu, Z.2
Xie, Z.3
Cheng, Z.4
Chen, Y.5
Tan, M.6
Luo, H.7
Zhang, Y.8
He, W.9
Yang, K.10
Zwaans, B.M.M.11
Tishkoff, D.12
Ho, L.13
Lombard, D.14
He, T.-C.15
Dai, J.16
Verdin, E.17
Ye, Y.18
Zhao, Y.19
-
6
-
-
81055122671
-
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
-
J. Du, Y. Zhou, X. Su, J.J. Yu, S. Khan, H. Jiang, J. Kim, J. Woo, J.H. Kim, B.H. Choi, B. He, W. Chen, S. Zhang, R.A. Cerione, J. Auwerx, Q. Hao, and H. Lin Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase Science 334 2011 806 809
-
(2011)
Science
, vol.334
, pp. 806-809
-
-
Du, J.1
Zhou, Y.2
Su, X.3
Yu, J.J.4
Khan, S.5
Jiang, H.6
Kim, J.7
Woo, J.8
Kim, J.H.9
Choi, B.H.10
He, B.11
Chen, W.12
Zhang, S.13
Cerione, R.A.14
Auwerx, J.15
Hao, Q.16
Lin, H.17
-
7
-
-
84871143981
-
Minireview series on sirtuins: From biochemistry to health and disease
-
J.M. Denu, and J.M. Gottesfeld Minireview series on sirtuins: from biochemistry to health and disease J. Biol. Chem. 287 2012 42417 42418
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 42417-42418
-
-
Denu, J.M.1
Gottesfeld, J.M.2
-
8
-
-
84867594869
-
Mitochondrial protein acetylation regulates metabolism
-
K.A. Anderson, and M.D. Hirschey Mitochondrial protein acetylation regulates metabolism Essays Biochem. 52 2012 23 35
-
(2012)
Essays Biochem.
, vol.52
, pp. 23-35
-
-
Anderson, K.A.1
Hirschey, M.D.2
-
9
-
-
77149148756
-
Regulation of cellular metabolism by protein lysine acetylation
-
S. Zhao, W. Xu, W. Jiang, W. Yu, Y. Lin, T. Zhang, J. Yao, L. Zhou, Y. Zeng, H. Li, Y. Li, J. Shi, W. An, S.M. Hancock, F. He, L. Qin, J. Chin, P. Yang, X. Chen, Q. Lei, Y. Xiong, and K.L. Guan Regulation of cellular metabolism by protein lysine acetylation Science 327 2010 1000 1004
-
(2010)
Science
, vol.327
, pp. 1000-1004
-
-
Zhao, S.1
Xu, W.2
Jiang, W.3
Yu, W.4
Lin, Y.5
Zhang, T.6
Yao, J.7
Zhou, L.8
Zeng, Y.9
Li, H.10
Li, Y.11
Shi, J.12
An, W.13
Hancock, S.M.14
He, F.15
Qin, L.16
Chin, J.17
Yang, P.18
Chen, X.19
Lei, Q.20
Xiong, Y.21
Guan, K.L.22
more..
-
10
-
-
68949212379
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions
-
C. Choudhary, C. Kumar, F. Gnad, M.L. Nielsen, M. Rehman, T.C. Walther, J.V. Olsen, and M. Mann Lysine acetylation targets protein complexes and co-regulates major cellular functions Science 325 2009 834 840
-
(2009)
Science
, vol.325
, pp. 834-840
-
-
Choudhary, C.1
Kumar, C.2
Gnad, F.3
Nielsen, M.L.4
Rehman, M.5
Walther, T.C.6
Olsen, J.V.7
Mann, M.8
-
11
-
-
33746992118
-
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey
-
S.C. Kim, R. Sprung, Y. Chen, Y. Xu, H. Ball, J. Pei, T. Cheng, Y. Kho, H. Xiao, L. Xiao, N.V. Grishin, M. White, X.J. Yang, and Y. Zhao Substrate and functional diversity of lysine acetylation revealed by a proteomics survey Mol. Cell 23 2006 607 618
-
(2006)
Mol. Cell
, vol.23
, pp. 607-618
-
-
Kim, S.C.1
Sprung, R.2
Chen, Y.3
Xu, Y.4
Ball, H.5
Pei, J.6
Cheng, T.7
Kho, Y.8
Xiao, H.9
Xiao, L.10
Grishin, N.V.11
White, M.12
Yang, X.J.13
Zhao, Y.14
-
12
-
-
84876217035
-
Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways
-
M.J. Rardin, J.C. Newman, J.M. Held, M.P. Cusack, D.J. Sorensen, B. Li, B. Schilling, S.D. Mooney, C.R. Kahn, E. Verdin, and B.W. Gibson Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways Proc. Natl. Acad. Sci. U. S. A. 110 2013 6601 6606
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 6601-6606
-
-
Rardin, M.J.1
Newman, J.C.2
Held, J.M.3
Cusack, M.P.4
Sorensen, D.J.5
Li, B.6
Schilling, B.7
Mooney, S.D.8
Kahn, C.R.9
Verdin, E.10
Gibson, B.W.11
-
13
-
-
34249083199
-
Sirtuins in mammals: Insights into their biological function
-
S. Michan, and D. Sinclair Sirtuins in mammals: insights into their biological function Biochem. J. 404 2007 1 13
-
(2007)
Biochem. J.
, vol.404
, pp. 1-13
-
-
Michan, S.1
Sinclair, D.2
-
14
-
-
84865421953
-
Mitochondrial sirtuins: Regulators of protein acylation and metabolism
-
W. He, J.C. Newman, M.Z. Wang, L. Ho, and E. Verdin Mitochondrial sirtuins: regulators of protein acylation and metabolism Trends Endocrinol. Metab. 23 2012 467 476
-
(2012)
Trends Endocrinol. Metab.
, vol.23
, pp. 467-476
-
-
He, W.1
Newman, J.C.2
Wang, M.Z.3
Ho, L.4
Verdin, E.5
-
15
-
-
78651162036
-
Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis
-
V.G. Allfrey, R. Faulkner, and A.E. Mirsky Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis Proc. Natl. Acad. Sci. U. S. A. 51 1964 786 794
-
(1964)
Proc. Natl. Acad. Sci. U. S. A.
, vol.51
, pp. 786-794
-
-
Allfrey, V.G.1
Faulkner, R.2
Mirsky, A.E.3
-
16
-
-
0030798245
-
Histone acetylation in chromatin structure and transcription
-
M. Grunstein Histone acetylation in chromatin structure and transcription Nature 389 1997 349 352
-
(1997)
Nature
, vol.389
, pp. 349-352
-
-
Grunstein, M.1
-
17
-
-
28044471827
-
Acetylation and deacetylation of non-histone proteins
-
M.A. Glozak, N. Sengupta, X. Zhang, and E. Seto Acetylation and deacetylation of non-histone proteins Gene 363 2005 15 23
-
(2005)
Gene
, vol.363
, pp. 15-23
-
-
Glozak, M.A.1
Sengupta, N.2
Zhang, X.3
Seto, E.4
-
18
-
-
77149120797
-
Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux
-
Q. Wang, Y. Zhang, C. Yang, H. Xiong, Y. Lin, J. Yao, H. Li, L. Xie, W. Zhao, Y. Yao, Z.B. Ning, R. Zeng, Y. Xiong, K.L. Guan, S. Zhao, and G.P. Zhao Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux Science 327 2010 1004 1007
-
(2010)
Science
, vol.327
, pp. 1004-1007
-
-
Wang, Q.1
Zhang, Y.2
Yang, C.3
Xiong, H.4
Lin, Y.5
Yao, J.6
Li, H.7
Xie, L.8
Zhao, W.9
Yao, Y.10
Ning, Z.B.11
Zeng, R.12
Xiong, Y.13
Guan, K.L.14
Zhao, S.15
Zhao, G.P.16
-
19
-
-
84865726581
-
Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns
-
A. Lundby, K. Lage, B.T. Weinert, D.B. Bekker-Jensen, A. Secher, T. Skovgaard, C.D. Kelstrup, A. Dmytriyev, C. Choudhary, C. Lundby, and J.V. Olsen Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns Cell. Reprogram. 2 2012 419 431
-
(2012)
Cell. Reprogram.
, vol.2
, pp. 419-431
-
-
Lundby, A.1
Lage, K.2
Weinert, B.T.3
Bekker-Jensen, D.B.4
Secher, A.5
Skovgaard, T.6
Kelstrup, C.D.7
Dmytriyev, A.8
Choudhary, C.9
Lundby, C.10
Olsen, J.V.11
-
20
-
-
84869215170
-
Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae
-
P. Henriksen, S.A. Wagner, B.T. Weinert, S. Sharma, G. Bacinskaja, M. Rehman, A.H. Juffer, T.C. Walther, M. Lisby, and C. Choudhary Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae Mol. Cell Proteomics 11 2012 1510 1522
-
(2012)
Mol. Cell Proteomics
, vol.11
, pp. 1510-1522
-
-
Henriksen, P.1
Wagner, S.A.2
Weinert, B.T.3
Sharma, S.4
Bacinskaja, G.5
Rehman, M.6
Juffer, A.H.7
Walther, T.C.8
Lisby, M.9
Choudhary, C.10
-
21
-
-
0034654011
-
Acetylation: A regulatory modification to rival phosphorylation?
-
T. Kouzarides Acetylation: a regulatory modification to rival phosphorylation? EMBO J. 19 2000 1176 1179
-
(2000)
EMBO J.
, vol.19
, pp. 1176-1179
-
-
Kouzarides, T.1
-
22
-
-
34547875773
-
Sirtuins: Critical regulators at the crossroads between cancer and aging
-
L.R. Saunders, and E. Verdin Sirtuins: critical regulators at the crossroads between cancer and aging Oncogene 26 2007 5489 5504
-
(2007)
Oncogene
, vol.26
, pp. 5489-5504
-
-
Saunders, L.R.1
Verdin, E.2
-
23
-
-
84865576222
-
Metabolic regulation by SIRT3: Implications for tumorigenesis
-
L.W.S. Finley, and M.C. Haigis Metabolic regulation by SIRT3: implications for tumorigenesis Trends Mol. Med. 18 2012 516 523
-
(2012)
Trends Mol. Med.
, vol.18
, pp. 516-523
-
-
Finley, L.W.S.1
Haigis, M.C.2
-
24
-
-
79551584971
-
Regulation of intermediary metabolism by protein acetylation
-
K.L. Guan, and Y. Xiong Regulation of intermediary metabolism by protein acetylation Trends Biochem. Sci. 36 2010 108 116
-
(2010)
Trends Biochem. Sci.
, vol.36
, pp. 108-116
-
-
Guan, K.L.1
Xiong, Y.2
-
25
-
-
78649328799
-
Sirtuin regulation of mitochondria: Energy production, apoptosis, and signaling
-
E. Verdin, M.D. Hirschey, L.W. Finley, and M.C. Haigis Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling Trends Biochem. Sci. 35 2010 669 675
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 669-675
-
-
Verdin, E.1
Hirschey, M.D.2
Finley, L.W.3
Haigis, M.C.4
-
26
-
-
84872276165
-
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome
-
A.S. Hebert, K.E. Dittenhafer-Reed, W. Yu, D.J. Bailey, E.S. Selen, M.D. Boersma, J.J. Carson, M. Tonelli, A.J. Balloon, A.J. Higbee, M.S. Westphall, D.J. Pagliarini, T.A. Prolla, F. Assadi-Porter, S. Roy, J.M. Denu, and J.J. Coon Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome Mol. Cell 49 2013 186 199
-
(2013)
Mol. Cell
, vol.49
, pp. 186-199
-
-
Hebert, A.S.1
Dittenhafer-Reed, K.E.2
Yu, W.3
Bailey, D.J.4
Selen, E.S.5
Boersma, M.D.6
Carson, J.J.7
Tonelli, M.8
Balloon, A.J.9
Higbee, A.J.10
Westphall, M.S.11
Pagliarini, D.J.12
Prolla, T.A.13
Assadi-Porter, F.14
Roy, S.15
Denu, J.M.16
Coon, J.J.17
-
27
-
-
84857883360
-
Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice
-
K.S. Fritz, J.J. Galligan, M. Hirschey, E. Verdin, and D.R. Petersen Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice J. Proteome Res. 11 2012 1633 1643
-
(2012)
J. Proteome Res.
, vol.11
, pp. 1633-1643
-
-
Fritz, K.S.1
Galligan, J.J.2
Hirschey, M.3
Verdin, E.4
Petersen, D.R.5
-
28
-
-
84870880080
-
Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase Sirt3
-
E.M. Sol, S.A. Wagner, B.T. Weinert, A. Kumar, H.-S. Kim, C.-X. Deng, and C. Choudhary Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase Sirt3 PLoS One 7 2012 e50545
-
(2012)
PLoS One
, vol.7
, pp. 50545
-
-
Sol, E.M.1
Wagner, S.A.2
Weinert, B.T.3
Kumar, A.4
Kim, H.-S.5
Deng, C.-X.6
Choudhary, C.7
-
29
-
-
78651468707
-
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction
-
W.C. Hallows, W. Yu, B.C. Smith, M.K. Devries, J.J. Ellinger, S. Someya, M.R. Shortreed, T. Prolla, J.L. Markley, L.M. Smith, S. Zhao, K.L. Guan, and J.M. Denu Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction Mol. Cell 41 2011 139 149
-
(2011)
Mol. Cell
, vol.41
, pp. 139-149
-
-
Hallows, W.C.1
Yu, W.2
Smith, B.C.3
Devries, M.K.4
Ellinger, J.J.5
Someya, S.6
Shortreed, M.R.7
Prolla, T.8
Markley, J.L.9
Smith, L.M.10
Zhao, S.11
Guan, K.L.12
Denu, J.M.13
-
30
-
-
77950806433
-
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
-
M.D. Hirschey, T. Shimazu, E. Goetzman, E. Jing, B. Schwer, D.B. Lombard, C.A. Grueter, C. Harris, S. Biddinger, O.R. Ilkayeva, R.D. Stevens, Y. Li, A.K. Saha, N.B. Ruderman, J.R. Bain, C.B. Newgard, R.V. Farese Jr., F.W. Alt, C.R. Kahn, and E. Verdin SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation Nature 464 2010 121 125
-
(2010)
Nature
, vol.464
, pp. 121-125
-
-
Hirschey, M.D.1
Shimazu, T.2
Goetzman, E.3
Jing, E.4
Schwer, B.5
Lombard, D.B.6
Grueter, C.A.7
Harris, C.8
Biddinger, S.9
Ilkayeva, O.R.10
Stevens, R.D.11
Li, Y.12
Saha, A.K.13
Ruderman, N.B.14
Bain, J.R.15
Newgard, C.B.16
Farese Jr., R.V.17
Alt, F.W.18
Kahn, C.R.19
Verdin, E.20
more..
-
31
-
-
0033887456
-
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
-
R.A. Frye Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins Biochem. Biophys. Res. Commun. 273 2000 793 798
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.273
, pp. 793-798
-
-
Frye, R.A.1
-
32
-
-
0031459980
-
Extrachromosomal rDNA circles - A cause of aging in yeast
-
D.A. Sinclair, and L. Guarente Extrachromosomal rDNA circles - a cause of aging in yeast Cell 91 1997 1033 1042
-
(1997)
Cell
, vol.91
, pp. 1033-1042
-
-
Sinclair, D.A.1
Guarente, L.2
-
33
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
H.A. Tissenbaum, and L. Guarente Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans Nature 410 2001 227 230
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
34
-
-
8644224064
-
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
-
B. Rogina, and S.L. Helfand Sir2 mediates longevity in the fly through a pathway related to calorie restriction Proc. Natl. Acad. Sci. U. S. A. 101 2004 15998 16003
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 15998-16003
-
-
Rogina, B.1
Helfand, S.L.2
-
35
-
-
84859909860
-
SRT1720 improves survival and healthspan of obese mice
-
R.K. Minor, J.A. Baur, A.P. Gomes, T.M. Ward, A. Csiszar, E.M. Mercken, K. Abdelmohsen, Y.K. Shin, C. Canto, M. Scheibye-Knudsen, M. Krawczyk, P.M. Irusta, A. Martin-Montalvo, B.P. Hubbard, Y. Zhang, E. Lehrmann, A.A. White, N.L. Price, W.R. Swindell, K.J. Pearson, K.G. Becker, V.A. Bohr, M. Gorospe, J.M. Egan, M.I. Talan, J. Auwerx, C.H. Westphal, J.L. Ellis, Z. Ungvari, G.P. Vlasuk, P.J. Elliott, D.A. Sinclair, and R. de Cabo SRT1720 improves survival and healthspan of obese mice Sci. Rep. 1 2011 70
-
(2011)
Sci. Rep.
, vol.1
, pp. 70
-
-
Minor, R.K.1
Baur, J.A.2
Gomes, A.P.3
Ward, T.M.4
Csiszar, A.5
Mercken, E.M.6
Abdelmohsen, K.7
Shin, Y.K.8
Canto, C.9
Scheibye-Knudsen, M.10
Krawczyk, M.11
Irusta, P.M.12
Martin-Montalvo, A.13
Hubbard, B.P.14
Zhang, Y.15
Lehrmann, E.16
White, A.A.17
Price, N.L.18
Swindell, W.R.19
Pearson, K.J.20
Becker, K.G.21
Bohr, V.A.22
Gorospe, M.23
Egan, J.M.24
Talan, M.I.25
Auwerx, J.26
Westphal, C.H.27
Ellis, J.L.28
Ungvari, Z.29
Vlasuk, G.P.30
Elliott, P.J.31
Sinclair, D.A.32
De Cabo, R.33
more..
-
36
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
-
M. Lagouge, C. Argmann, Z. Gerhart-Hines, H. Meziane, C. Lerin, F. Daussin, N. Messadeq, J. Milne, P. Lambert, P. Elliott, B. Geny, M. Laakso, P. Puigserver, and J. Auwerx Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha Cell 127 2006 1109 1122
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
Geny, B.11
Laakso, M.12
Puigserver, P.13
Auwerx, J.14
-
37
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
K.T. Howitz, K.J. Bitterman, H.Y. Cohen, D.W. Lamming, S. Lavu, J.G. Wood, R.E. Zipkin, P. Chung, A. Kisielewski, L.L. Zhang, B. Scherer, and D.A. Sinclair Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan Nature 425 2003 191 196
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
Scherer, B.11
Sinclair, D.A.12
-
38
-
-
84875881601
-
SIRT6 regulates TNF-[agr] secretion through hydrolysis of long-chain fatty acyl lysine
-
H. Jiang, S. Khan, Y. Wang, G. Charron, B. He, C. Sebastian, J. Du, R. Kim, E. Ge, R. Mostoslavsky, H.C. Hang, Q. Hao, and H. Lin SIRT6 regulates TNF-[agr] secretion through hydrolysis of long-chain fatty acyl lysine Nature 496 2013 110 113
-
(2013)
Nature
, vol.496
, pp. 110-113
-
-
Jiang, H.1
Khan, S.2
Wang, Y.3
Charron, G.4
He, B.5
Sebastian, C.6
Du, J.7
Kim, R.8
Ge, E.9
Mostoslavsky, R.10
Hang, H.C.11
Hao, Q.12
Lin, H.13
-
39
-
-
33748316536
-
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells
-
M.C. Haigis, R. Mostoslavsky, K.M. Haigis, K. Fahie, D.C. Christodoulou, A.J. Murphy, D.M. Valenzuela, G.D. Yancopoulos, M. Karow, G. Blander, C. Wolberger, T.A. Prolla, R. Weindruch, F.W. Alt, and L. Guarente SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells Cell 126 2006 941 954
-
(2006)
Cell
, vol.126
, pp. 941-954
-
-
Haigis, M.C.1
Mostoslavsky, R.2
Haigis, K.M.3
Fahie, K.4
Christodoulou, D.C.5
Murphy, A.J.6
Valenzuela, D.M.7
Yancopoulos, G.D.8
Karow, M.9
Blander, G.10
Wolberger, C.11
Prolla, T.A.12
Weindruch, R.13
Alt, F.W.14
Guarente, L.15
-
40
-
-
84860192261
-
Identification of a molecular component of the mitochondrial acetyl transferase program; A novel role for GCN5L1
-
I. Scott, B.R. Webster, J.H. Li, and M.N. Sack Identification of a molecular component of the mitochondrial acetyl transferase program; a novel role for GCN5L1 Biochem. J. 443 2012 655 661
-
(2012)
Biochem. J.
, vol.443
, pp. 655-661
-
-
Scott, I.1
Webster, B.R.2
Li, J.H.3
Sack, M.N.4
-
42
-
-
0037135972
-
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
-
B. Schwer, B.J. North, R.A. Frye, M. Ott, and E. Verdin The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase J. Cell. Biol. 158 2002 647 657
-
(2002)
J. Cell. Biol.
, vol.158
, pp. 647-657
-
-
Schwer, B.1
North, B.J.2
Frye, R.A.3
Ott, M.4
Verdin, E.5
-
43
-
-
84871852995
-
SIRT3 functions in the nucleus in the control of stress-related gene expression
-
T. Iwahara, R. Bonasio, V. Narendra, and D. Reinberg SIRT3 functions in the nucleus in the control of stress-related gene expression Mol. Cell. Biol. 32 2012 5022 5034
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 5022-5034
-
-
Iwahara, T.1
Bonasio, R.2
Narendra, V.3
Reinberg, D.4
-
44
-
-
34247271282
-
SirT3 is a nuclear NAD+dependent histone deacetylase that translocates to the mitochondria upon cellular stress
-
M.B. Scher, A. Vaquero, and D. Reinberg SirT3 is a nuclear NAD+dependent histone deacetylase that translocates to the mitochondria upon cellular stress Genes Dev. 21 2007 920 928
-
(2007)
Genes Dev.
, vol.21
, pp. 920-928
-
-
Scher, M.B.1
Vaquero, A.2
Reinberg, D.3
-
45
-
-
42449128019
-
Where in the cell is SIRT3? - Functional localization of an NAD+dependent protein deacetylase
-
W.C. Hallows, B.N. Albaugh, and J.M. Denu Where in the cell is SIRT3? - functional localization of an NAD+dependent protein deacetylase Biochem. J. 411 2008 e11 e13
-
(2008)
Biochem. J.
, vol.411
-
-
Hallows, W.C.1
Albaugh, B.N.2
Denu, J.M.3
-
46
-
-
84860228592
-
In mammalian muscle, SIRT3 is present in mitochondria and not in the nucleus; And SIRT3 is upregulated by chronic muscle contraction in an adenosine monophosphate-activated protein kinase-independent manner
-
B.J. Gurd, G.P. Holloway, Y. Yoshida, and A. Bonen In mammalian muscle, SIRT3 is present in mitochondria and not in the nucleus; and SIRT3 is upregulated by chronic muscle contraction in an adenosine monophosphate- activated protein kinase-independent manner Metabolism 61 2012 733 741
-
(2012)
Metabolism
, vol.61
, pp. 733-741
-
-
Gurd, B.J.1
Holloway, G.P.2
Yoshida, Y.3
Bonen, A.4
-
47
-
-
42449132299
-
The human Sirt3 protein deacetylase is exclusively mitochondrial
-
H.M. Cooper, and J.N. Spelbrink The human Sirt3 protein deacetylase is exclusively mitochondrial Biochem. J. 411 2008 279 285
-
(2008)
Biochem. J.
, vol.411
, pp. 279-285
-
-
Cooper, H.M.1
Spelbrink, J.N.2
-
48
-
-
37549002891
-
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
-
D.B. Lombard, F.W. Alt, H.L. Cheng, J. Bunkenborg, R.S. Streeper, R. Mostoslavsky, J. Kim, G. Yancopoulos, D. Valenzuela, A. Murphy, Y. Yang, Y. Chen, M.D. Hirschey, R.T. Bronson, M. Haigis, L.P. Guarente, R.V. Farese Jr., S. Weissman, E. Verdin, and B. Schwer Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation Mol. Cell. Biol. 27 2007 8807 8814
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 8807-8814
-
-
Lombard, D.B.1
Alt, F.W.2
Cheng, H.L.3
Bunkenborg, J.4
Streeper, R.S.5
Mostoslavsky, R.6
Kim, J.7
Yancopoulos, G.8
Valenzuela, D.9
Murphy, A.10
Yang, Y.11
Chen, Y.12
Hirschey, M.D.13
Bronson, R.T.14
Haigis, M.15
Guarente, L.P.16
Farese Jr., R.V.17
Weissman, S.18
Verdin, E.19
Schwer, B.20
more..
-
49
-
-
77952940043
-
Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle
-
O.M. Palacios, J.J. Carmona, S. Michan, K.Y. Chen, Y. Manabe, J.L. Ward III, L.J. Goodyear, and Q. Tong Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle Aging (Albany NY) 1 2009 771 783
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 771-783
-
-
Palacios, O.M.1
Carmona, J.J.2
Michan, S.3
Chen, K.Y.4
Manabe, Y.5
Ward III, J.L.6
Goodyear, L.J.7
Tong, Q.8
-
50
-
-
82455212901
-
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome
-
M.D. Hirschey, T. Shimazu, E. Jing, C.A. Grueter, A.M. Collins, B. Aouizerat, A. Stanc·kov, E. Goetzman, M.M. Lam, B. Schwer, R.D. Stevens, M.J. Muehlbauer, S. Kakar, N.M. Bass, J. Kuusisto, M. Laakso, F.W. Alt, C.B. Newgard, R.V. Farese Jr., C.R. Kahn, and E. Verdin SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome Mol. Cell 44 2011 177 190
-
(2011)
Mol. Cell
, vol.44
, pp. 177-190
-
-
Hirschey, M.D.1
Shimazu, T.2
Jing, E.3
Grueter, C.A.4
Collins, A.M.5
Aouizerat, B.6
Stanckov, A.7
Goetzman, E.8
Lam, M.M.9
Schwer, B.10
Stevens, R.D.11
Muehlbauer, M.J.12
Kakar, S.13
Bass, N.M.14
Kuusisto, J.15
Laakso, M.16
Alt, F.W.17
Newgard, C.B.18
Farese Jr., R.V.19
Kahn, C.R.20
Verdin, E.21
more..
-
51
-
-
73949123433
-
Calorie restriction alters mitochondrial protein acetylation
-
B. Schwer, M. Eckersdorff, Y. Li, J.C. Silva, D. Fermin, M.V. Kurtev, C. Giallourakis, M.J. Comb, F.W. Alt, and D.B. Lombard Calorie restriction alters mitochondrial protein acetylation Aging Cell 8 2009 604 606
-
(2009)
Aging Cell
, vol.8
, pp. 604-606
-
-
Schwer, B.1
Eckersdorff, M.2
Li, Y.3
Silva, J.C.4
Fermin, D.5
Kurtev, M.V.6
Giallourakis, C.7
Comb, M.J.8
Alt, F.W.9
Lombard, D.B.10
-
52
-
-
84891506172
-
Sirt3 Regulates Metabolic Flexibility of Skeletal Muscle through Reversible Enzymatic Deacetylation
-
10.2337/db2312-1650 (in press)
-
E. Jing, B.T. O'ÄôNeill, M.J. Rardin, A. Kleinridders, O.R. Ilkeyeva, S. Ussar, J.R. Bain, K.Y. Lee, E.M. Verdin, C.B. Newgard, B.W. Gibson, and C.R. Kahn Sirt3 Regulates Metabolic Flexibility of Skeletal Muscle through Reversible Enzymatic Deacetylation Diabetes 2013 10.2337/db2312-1650 (in press)
-
(2013)
Diabetes
-
-
Jing, E.1
O'Äôneill, B.T.2
Rardin, M.J.3
Kleinridders, A.4
Ilkeyeva, O.R.5
Ussar, S.6
Bain, J.R.7
Lee, K.Y.8
Verdin, E.M.9
Newgard, C.B.10
Gibson, B.W.11
Kahn, C.R.12
-
53
-
-
78751513117
-
Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation
-
A.A. Kendrick, M. Choudhury, S.M. Rahman, C.E. McCurdy, M. Friederich, J.L. Van Hove, P.A. Watson, N. Birdsey, J. Bao, D. Gius, M.N. Sack, E. Jing, C.R. Kahn, J.E. Friedman, and K.R. Jonscher Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation Biochem. J. 433 2011 505 514
-
(2011)
Biochem. J.
, vol.433
, pp. 505-514
-
-
Kendrick, A.A.1
Choudhury, M.2
Rahman, S.M.3
McCurdy, C.E.4
Friederich, M.5
Van Hove, J.L.6
Watson, P.A.7
Birdsey, N.8
Bao, J.9
Gius, D.10
Sack, M.N.11
Jing, E.12
Kahn, C.R.13
Friedman, J.E.14
Jonscher, K.R.15
-
54
-
-
77956173286
-
SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity
-
J. Bao, I. Scott, Z. Lu, L. Pang, C.C. Dimond, D. Gius, and M.N. Sack SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity Free Radic. Biol. Med. 49 2010 1230 1237
-
(2010)
Free Radic. Biol. Med.
, vol.49
, pp. 1230-1237
-
-
Bao, J.1
Scott, I.2
Lu, Z.3
Pang, L.4
Dimond, C.C.5
Gius, D.6
Sack, M.N.7
-
55
-
-
80052291180
-
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
-
E. Jing, B. Emanuelli, M.D. Hirschey, J. Boucher, K.Y. Lee, D. Lombard, E.M. Verdin, and C.R. Kahn Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production Proc. Natl. Acad. Sci. 108 2011 14608 14613
-
(2011)
Proc. Natl. Acad. Sci.
, vol.108
, pp. 14608-14613
-
-
Jing, E.1
Emanuelli, B.2
Hirschey, M.D.3
Boucher, J.4
Lee, K.Y.5
Lombard, D.6
Verdin, E.M.7
Kahn, C.R.8
-
56
-
-
33745889628
-
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
-
B. Schwer, J. Bunkenborg, R.O. Verdin, J.S. Andersen, and E. Verdin Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2 Proc. Natl. Acad. Sci. U. S. A. 103 2006 10224 10229
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 10224-10229
-
-
Schwer, B.1
Bunkenborg, J.2
Verdin, R.O.3
Andersen, J.S.4
Verdin, E.5
-
57
-
-
33745931074
-
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
-
W.C. Hallows, S. Lee, and J.M. Denu Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases Proc. Natl. Acad. Sci. U. S. A. 103 2006 10230 10235
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 10230-10235
-
-
Hallows, W.C.1
Lee, S.2
Denu, J.M.3
-
58
-
-
55749084738
-
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
-
B.H. Ahn, H.S. Kim, S. Song, I.H. Lee, J. Liu, A. Vassilopoulos, C.X. Deng, and T. Finkel A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis Proc. Natl. Acad. Sci. U. S. A. 105 2008 14447 14452
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 14447-14452
-
-
Ahn, B.H.1
Kim, H.S.2
Song, S.3
Lee, I.H.4
Liu, J.5
Vassilopoulos, A.6
Deng, C.X.7
Finkel, T.8
-
59
-
-
78649509214
-
SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production
-
T. Shimazu, M.D. Hirschey, L. Hua, K.E. Dittenhafer-Reed, B. Schwer, D.B. Lombard, Y. Li, J. Bunkenborg, F.W. Alt, J.M. Denu, M.P. Jacobson, and E. Verdin SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production Cell Metab. 12 2010 654 661
-
(2010)
Cell Metab.
, vol.12
, pp. 654-661
-
-
Shimazu, T.1
Hirschey, M.D.2
Hua, L.3
Dittenhafer-Reed, K.E.4
Schwer, B.5
Lombard, D.B.6
Li, Y.7
Bunkenborg, J.8
Alt, F.W.9
Denu, J.M.10
Jacobson, M.P.11
Verdin, E.12
-
60
-
-
75349111140
-
Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria
-
H. Cimen, M.J. Han, Y. Yang, Q. Tong, H. Koc, and E.C. Koc Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria Biochemistry 49 2010 304 311
-
(2010)
Biochemistry
, vol.49
, pp. 304-311
-
-
Cimen, H.1
Han, M.J.2
Yang, Y.3
Tong, Q.4
Koc, H.5
Koc, E.C.6
-
61
-
-
80051716282
-
Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity
-
L.W. Finley, W. Haas, V. Desquiret-Dumas, D.C. Wallace, V. Procaccio, S.P. Gygi, and M.C. Haigis Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity PLoS One 6 2011 e23295
-
(2011)
PLoS One
, vol.6
, pp. 23295
-
-
Finley, L.W.1
Haas, W.2
Desquiret-Dumas, V.3
Wallace, D.C.4
Procaccio, V.5
Gygi, S.P.6
Haigis, M.C.7
-
62
-
-
78651468722
-
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
-
S. Someya, W. Yu, W.C. Hallows, J. Xu, J.M. Vann, C. Leeuwenburgh, M. Tanokura, J.M. Denu, and T.A. Prolla Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction Cell 143 2010 802 812
-
(2010)
Cell
, vol.143
, pp. 802-812
-
-
Someya, S.1
Yu, W.2
Hallows, W.C.3
Xu, J.4
Vann, J.M.5
Leeuwenburgh, C.6
Tanokura, M.7
Denu, J.M.8
Prolla, T.A.9
-
63
-
-
78649521247
-
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
-
X. Qiu, K. Brown, M.D. Hirschey, E. Verdin, and D. Chen Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation Cell Metab. 12 2010 662 667
-
(2010)
Cell Metab.
, vol.12
, pp. 662-667
-
-
Qiu, X.1
Brown, K.2
Hirschey, M.D.3
Verdin, E.4
Chen, D.5
-
64
-
-
78650248160
-
Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress
-
R. Tao, M.C. Coleman, J.D. Pennington, O. Ozden, S.H. Park, H. Jiang, H.S. Kim, C.R. Flynn, S. Hill, W. Hayes McDonald, A.K. Olivier, D.R. Spitz, and D. Gius Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress Mol. Cell 40 2010 893 904
-
(2010)
Mol. Cell
, vol.40
, pp. 893-904
-
-
Tao, R.1
Coleman, M.C.2
Pennington, J.D.3
Ozden, O.4
Park, S.H.5
Jiang, H.6
Kim, H.S.7
Flynn, C.R.8
Hill, S.9
Hayes McDonald, W.10
Olivier, A.K.11
Spitz, D.R.12
Gius, D.13
-
65
-
-
53549105529
-
SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
-
N.R. Sundaresan, S.A. Samant, V.B. Pillai, S.B. Rajamohan, and M.P. Gupta SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70 Mol. Cell. Biol. 28 2008 6384 6401
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 6384-6401
-
-
Sundaresan, N.R.1
Samant, S.A.2
Pillai, V.B.3
Rajamohan, S.B.4
Gupta, M.P.5
-
66
-
-
79952266729
-
Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy
-
A.V. Hafner, J. Dai, A.P. Gomes, C.Y. Xiao, C.M. Palmeira, A. Rosenzweig, and D.A. Sinclair Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy Aging (Albany NY) 2 2010 914 923
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 914-923
-
-
Hafner, A.V.1
Dai, J.2
Gomes, A.P.3
Xiao, C.Y.4
Palmeira, C.M.5
Rosenzweig, A.6
Sinclair, D.A.7
-
67
-
-
80051796665
-
SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells
-
T. Koyama, S. Kume, D. Koya, S. Araki, K. Isshiki, M. Chin-Kanasaki, T. Sugimoto, M. Haneda, T. Sugaya, A. Kashiwagi, H. Maegawa, and T. Uzu SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells Free Radic. Biol. Med. 51 2011 1258 1267
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 1258-1267
-
-
Koyama, T.1
Kume, S.2
Koya, D.3
Araki, S.4
Isshiki, K.5
Chin-Kanasaki, M.6
Sugimoto, T.7
Haneda, M.8
Sugaya, T.9
Kashiwagi, A.10
Maegawa, H.11
Uzu, T.12
-
68
-
-
79952501323
-
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization
-
L.W. Finley, A. Carracedo, J. Lee, A. Souza, A. Egia, J. Zhang, J. Teruya-Feldstein, P.I. Moreira, S.M. Cardoso, C.B. Clish, P.P. Pandolfi, and M.C. Haigis SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization Cancer Cell 19 2011 416 428
-
(2011)
Cancer Cell
, vol.19
, pp. 416-428
-
-
Finley, L.W.1
Carracedo, A.2
Lee, J.3
Souza, A.4
Egia, A.5
Zhang, J.6
Teruya-Feldstein, J.7
Moreira, P.I.8
Cardoso, S.M.9
Clish, C.B.10
Pandolfi, P.P.11
Haigis, M.C.12
-
69
-
-
74049094817
-
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
-
H.S. Kim, K. Patel, K. Muldoon-Jacobs, K.S. Bisht, N. Aykin-Burns, J.D. Pennington, R. van der Meer, P. Nguyen, J. Savage, K.M. Owens, A. Vassilopoulos, O. Ozden, S.H. Park, K.K. Singh, S.A. Abdulkadir, D.R. Spitz, C.X. Deng, and D. Gius SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress Cancer Cell 17 2010 41 52
-
(2010)
Cancer Cell
, vol.17
, pp. 41-52
-
-
Kim, H.S.1
Patel, K.2
Muldoon-Jacobs, K.3
Bisht, K.S.4
Aykin-Burns, N.5
Pennington, J.D.6
Van Der Meer, R.7
Nguyen, P.8
Savage, J.9
Owens, K.M.10
Vassilopoulos, A.11
Ozden, O.12
Park, S.H.13
Singh, K.K.14
Abdulkadir, S.A.15
Spitz, D.R.16
Deng, C.X.17
Gius, D.18
-
70
-
-
79959819034
-
SirT3 suppresses hypoxia inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS production
-
E.L. Bell, B.M. Emerling, S.J. Ricoult, and L. Guarente SirT3 suppresses hypoxia inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS production Oncogene 30 2011 2986 2996
-
(2011)
Oncogene
, vol.30
, pp. 2986-2996
-
-
Bell, E.L.1
Emerling, B.M.2
Ricoult, S.J.3
Guarente, L.4
-
71
-
-
77951176793
-
Sirtuin-3 deacetylation of cyclophilin D induces dissociation of hexokinase II from the mitochondria
-
N. Shulga, R. Wilson-Smith, and J.G. Pastorino Sirtuin-3 deacetylation of cyclophilin D induces dissociation of hexokinase II from the mitochondria J. Cell Sci. 123 2010 894 902
-
(2010)
J. Cell Sci.
, vol.123
, pp. 894-902
-
-
Shulga, N.1
Wilson-Smith, R.2
Pastorino, J.G.3
-
72
-
-
79953799195
-
Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer
-
T.Y. Alhazzazi, P. Kamarajan, N. Joo, J.Y. Huang, E. Verdin, N.J. D'Silva, and Y.L. Kapila Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer Cancer 117 2011 1670 1678
-
(2011)
Cancer
, vol.117
, pp. 1670-1678
-
-
Alhazzazi, T.Y.1
Kamarajan, P.2
Joo, N.3
Huang, J.Y.4
Verdin, E.5
D'Silva, N.J.6
Kapila, Y.L.7
-
73
-
-
84875622163
-
Sirtuin-3 modulates Bak- and Bax-dependent apoptosis
-
M. Verma, N. Shulga, and J.G. Pastorino Sirtuin-3 modulates Bak- and Bax-dependent apoptosis J. Cell Sci. 126 2013 274 288
-
(2013)
J. Cell Sci.
, vol.126
, pp. 274-288
-
-
Verma, M.1
Shulga, N.2
Pastorino, J.G.3
-
74
-
-
84861589885
-
Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis
-
P.J. Fernandez-Marcos, E.H. Jeninga, C. Canto, T. Harach, V.C. de Boer, P. Andreux, N. Moullan, E. Pirinen, H. Yamamoto, S.M. Houten, K. Schoonjans, and J. Auwerx Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis Sci. Rep. 2 2012 425
-
(2012)
Sci. Rep.
, vol.2
, pp. 425
-
-
Fernandez-Marcos, P.J.1
Jeninga, E.H.2
Canto, C.3
Harach, T.4
De Boer, V.C.5
Andreux, P.6
Moullan, N.7
Pirinen, E.8
Yamamoto, H.9
Houten, S.M.10
Schoonjans, K.11
Auwerx, J.12
-
75
-
-
65249091951
-
Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD
-
J. Du, H. Jiang, and H. Lin Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD Biochemistry 48 2009 2878 2890
-
(2009)
Biochemistry
, vol.48
, pp. 2878-2890
-
-
Du, J.1
Jiang, H.2
Lin, H.3
-
76
-
-
36349030394
-
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase
-
N. Ahuja, B. Schwer, S. Carobbio, D. Waltregny, B.J. North, V. Castronovo, P. Maechler, and E. Verdin Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase J. Biol. Chem. 282 2007 33583 33592
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 33583-33592
-
-
Ahuja, N.1
Schwer, B.2
Carobbio, S.3
Waltregny, D.4
North, B.J.5
Castronovo, V.6
Maechler, P.7
Verdin, E.8
-
77
-
-
77957762687
-
SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells
-
N. Nasrin, X. Wu, E. Fortier, Y. Feng, O.C. Bare, S. Chen, X. Ren, Z. Wu, R.S. Streeper, and L. Bordone SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells J. Biol. Chem. 285 2010 31995 32002
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 31995-32002
-
-
Nasrin, N.1
Wu, X.2
Fortier, E.3
Feng, Y.4
Bare, O.C.5
Chen, S.6
Ren, X.7
Wu, Z.8
Streeper, R.S.9
Bordone, L.10
-
78
-
-
84867746901
-
Sirtuin-4 modulates sensitivity to induction of the mitochondrial permeability transition pore
-
M. Verma, N. Shulga, and J.G. Pastorino Sirtuin-4 modulates sensitivity to induction of the mitochondrial permeability transition pore Biochim. Biophys. Acta 1827 2013 38 49
-
(2013)
Biochim. Biophys. Acta
, vol.1827
, pp. 38-49
-
-
Verma, M.1
Shulga, N.2
Pastorino, J.G.3
-
79
-
-
84876359638
-
SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism
-
S.M. Jeong, C. Xiao, L.W.S. Finley, T. Lahusen, A.L. Souza, K. Pierce, Y.-H. Li, X. Wang, G. Laurent, N.J. German, X. Xu, C. Li, R.-H. Wang, J. Lee, A. Csibi, R. Cerione, J. Blenis, C.B. Clish, A. Kimmelman, C.-X. Deng, and M.C. Haigis SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism Cancer Cell 23 2013 450 463
-
(2013)
Cancer Cell
, vol.23
, pp. 450-463
-
-
Jeong, S.M.1
Xiao, C.2
Finley, L.W.S.3
Lahusen, T.4
Souza, A.L.5
Pierce, K.6
Li, Y.-H.7
Wang, X.8
Laurent, G.9
German, N.J.10
Xu, X.11
Li, C.12
Wang, R.-H.13
Lee, J.14
Csibi, A.15
Cerione, R.16
Blenis, J.17
Clish, C.B.18
Kimmelman, A.19
Deng, C.-X.20
Haigis, M.C.21
more..
-
80
-
-
84878891625
-
SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase
-
G. Laurent, N.J. German, A.K. Saha, V.C. de Boer, M. Davies, T.R. Koves, N. Dephoure, F. Fischer, G. Boanca, B. Vaitheesvaran, S.B. Lovitch, A.H. Sharpe, I.J. Kurland, C. Steegborn, S.P. Gygi, D.M. Muoio, N.B. Ruderman, and M.C. Haigis SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase Mol. Cell 50 2013 686 698
-
(2013)
Mol. Cell
, vol.50
, pp. 686-698
-
-
Laurent, G.1
German, N.J.2
Saha, A.K.3
De Boer, V.C.4
Davies, M.5
Koves, T.R.6
Dephoure, N.7
Fischer, F.8
Boanca, G.9
Vaitheesvaran, B.10
Lovitch, S.B.11
Sharpe, A.H.12
Kurland, I.J.13
Steegborn, C.14
Gygi, S.P.15
Muoio, D.M.16
Ruderman, N.B.17
Haigis, M.C.18
-
81
-
-
65249087389
-
SIRT5 deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle
-
T. Nakagawa, D.J. Lomb, M.C. Haigis, and L. Guarente SIRT5 deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle Cell 137 2009 560 570
-
(2009)
Cell
, vol.137
, pp. 560-570
-
-
Nakagawa, T.1
Lomb, D.J.2
Haigis, M.C.3
Guarente, L.4
-
82
-
-
77249128352
-
Overexpression of SIRT5 confirms its involvement in deacetylation and activation of carbamoyl phosphate synthetase 1
-
M. Ogura, Y. Nakamura, D. Tanaka, X. Zhuang, Y. Fujita, A. Obara, A. Hamasaki, M. Hosokawa, and N. Inagaki Overexpression of SIRT5 confirms its involvement in deacetylation and activation of carbamoyl phosphate synthetase 1 Biochem. Biophys. Res. Commun. 393 2010 73 78
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.393
, pp. 73-78
-
-
Ogura, M.1
Nakamura, Y.2
Tanaka, D.3
Zhuang, X.4
Fujita, Y.5
Obara, A.6
Hamasaki, A.7
Hosokawa, M.8
Inagaki, N.9
-
83
-
-
78650516004
-
Identification of lysine succinylation as a new post-translational modification
-
Z. Zhang, M. Tan, Z. Xie, L. Dai, Y. Chen, and Y. Zhao Identification of lysine succinylation as a new post-translational modification Nat. Chem. Biol. 7 2011 58 63
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 58-63
-
-
Zhang, Z.1
Tan, M.2
Xie, Z.3
Dai, L.4
Chen, Y.5
Zhao, Y.6
-
85
-
-
84864062918
-
Sirtuin 1 and sirtuin 3: Physiological modulators of metabolism
-
R. Nogueiras, K.M. Habegger, N. Chaudhary, B. Finan, A.S. Banks, M.O. Dietrich, T.L. Horvath, D.A. Sinclair, P.T. Pfluger, and M.H. Tschop Sirtuin 1 and sirtuin 3: physiological modulators of metabolism Physiol. Rev. 92 2012 1479 1514
-
(2012)
Physiol. Rev.
, vol.92
, pp. 1479-1514
-
-
Nogueiras, R.1
Habegger, K.M.2
Chaudhary, N.3
Finan, B.4
Banks, A.S.5
Dietrich, M.O.6
Horvath, T.L.7
Sinclair, D.A.8
Pfluger, P.T.9
Tschop, M.H.10
|