SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells

Free Radical Biology and Medicine

Volumn 51, Issue 6, 2011, Pages 1258-1267

  Koyama, Tetsuro ^a   Kume, Shinji ^a   Koya, Daisuke ^b   Araki, Shin Ichi ^a   Isshiki, Keiji ^a   Chin Kanasaki, Masami ^a   Sugimoto, Toshiro ^a   Haneda, Masakazu ^c   Sugaya, Takeshi ^d   Kashiwagi, Atsunori ^a   Maegawa, Hiroshi ^a   Uzu, Takashi ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

^c ASAHIKAWA MEDICAL COLLEGE   (Japan)

^d ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Diabetic nephropathy; Free radicals; Mitochondria; Oxidative stress; Palmitate; Proximal tubular cells; SIRT3

Indexed keywords

MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; SIRTUIN 3; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KIDNEY PROXIMAL TUBULE; LIPOTOXICITY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL LIPOTOXICITY; RETROVIRUS; TUBULOINTERSTITIAL INFLAMMATION; UPREGULATION;

ANIMALS; CALORIC RESTRICTION; CELLS, CULTURED; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; KIDNEY TUBULES, PROXIMAL; MICE; MUTATION; NEPHRITIS, INTERSTITIAL; OXIDATIVE STRESS; PALMITATES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIRTUIN 3; TRANSGENES;

EID: 80051796665     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.05.028     Document Type: Article

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