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Volumn 20, Issue 3, 2014, Pages 154-165

Pathomechanisms: Homeostatic chemokines in health, tissue regeneration, and progressive diseases

Author keywords

Chemokine receptor; Inflammation; Malignancy; Regeneration; Tissue damage

Indexed keywords

CHEMOKINE RECEPTOR; INFLAMMATION; MALIGNANCY; REGENERATION; TISSUE DAMAGE;

EID: 84894454703     PISSN: 14714914     EISSN: 1471499X     Source Type: Journal    
DOI: 10.1016/j.molmed.2013.12.002     Document Type: Review
Times cited : (70)

References (106)
  • 1
    • 84859550605 scopus 로고    scopus 로고
    • The stem cell niche in regenerative medicine
    • Wagers A.J. The stem cell niche in regenerative medicine. Cell Stem Cell 2012, 10:362-369.
    • (2012) Cell Stem Cell , vol.10 , pp. 362-369
    • Wagers, A.J.1
  • 2
    • 78649639492 scopus 로고    scopus 로고
    • Tissue-resident adult stem cell populations of rapidly self-renewing organs
    • Barker N., et al. Tissue-resident adult stem cell populations of rapidly self-renewing organs. Cell Stem Cell 2010, 7:656-670.
    • (2010) Cell Stem Cell , vol.7 , pp. 656-670
    • Barker, N.1
  • 3
    • 60849136593 scopus 로고    scopus 로고
    • Mesenchymal stem cell homing: the devil is in the details
    • Karp J.M., Leng Teo G.S. Mesenchymal stem cell homing: the devil is in the details. Cell Stem Cell 2009, 4:206-216.
    • (2009) Cell Stem Cell , vol.4 , pp. 206-216
    • Karp, J.M.1    Leng Teo, G.S.2
  • 4
    • 84871616815 scopus 로고    scopus 로고
    • Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history
    • Nomiyama H., et al. Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history. Genes Cells 2013, 18:1-16.
    • (2013) Genes Cells , vol.18 , pp. 1-16
    • Nomiyama, H.1
  • 5
    • 84862184616 scopus 로고    scopus 로고
    • Overview of the mechanisms regulating chemokine activity and availability
    • Mortier A., et al. Overview of the mechanisms regulating chemokine activity and availability. Immunol. Lett. 2012, 145:2-9.
    • (2012) Immunol. Lett. , vol.145 , pp. 2-9
    • Mortier, A.1
  • 6
    • 0032499260 scopus 로고    scopus 로고
    • Chemokines and leukocyte traffic
    • Baggiolini M. Chemokines and leukocyte traffic. Nature 1998, 392:565-568.
    • (1998) Nature , vol.392 , pp. 565-568
    • Baggiolini, M.1
  • 7
    • 42649122256 scopus 로고    scopus 로고
    • Development of secondary lymphoid organs
    • Randall T.D., et al. Development of secondary lymphoid organs. Annu. Rev. Immunol. 2008, 26:627-650.
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 627-650
    • Randall, T.D.1
  • 8
    • 2342650412 scopus 로고    scopus 로고
    • The impact of CCR7 and CXCR5 on lymphoid organ development and systemic immunity
    • Muller G., et al. The impact of CCR7 and CXCR5 on lymphoid organ development and systemic immunity. Immunol. Rev. 2003, 195:117-135.
    • (2003) Immunol. Rev. , vol.195 , pp. 117-135
    • Muller, G.1
  • 9
    • 0028324454 scopus 로고
    • Molecular cloning and structure of a pre-B-cell growth-stimulating factor
    • Nagasawa T., et al. Molecular cloning and structure of a pre-B-cell growth-stimulating factor. Proc. Natl. Acad. Sci. U.S.A. 1994, 91:2305-2309.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 2305-2309
    • Nagasawa, T.1
  • 10
    • 0038500953 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and G(alpha)i proteins and enhances engraftment of competitive, repopulating stem cells
    • Broxmeyer H.E., et al. Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and G(alpha)i proteins and enhances engraftment of competitive, repopulating stem cells. J. Leukoc. Biol. 2003, 73:630-638.
    • (2003) J. Leukoc. Biol. , vol.73 , pp. 630-638
    • Broxmeyer, H.E.1
  • 11
    • 0037097581 scopus 로고    scopus 로고
    • Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines
    • Lee Y., et al. Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines. Blood 2002, 99:4307-4317.
    • (2002) Blood , vol.99 , pp. 4307-4317
    • Lee, Y.1
  • 12
    • 84859640534 scopus 로고    scopus 로고
    • The bone marrow-expressed antimicrobial cationic peptide LL-37 enhances the responsiveness of hematopoietic stem progenitor cells to an SDF-1 gradient and accelerates their engraftment after transplantation
    • Wu W., et al. The bone marrow-expressed antimicrobial cationic peptide LL-37 enhances the responsiveness of hematopoietic stem progenitor cells to an SDF-1 gradient and accelerates their engraftment after transplantation. Leukemia 2012, 26:736-745.
    • (2012) Leukemia , vol.26 , pp. 736-745
    • Wu, W.1
  • 13
    • 11144358161 scopus 로고    scopus 로고
    • CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow
    • Avigdor A., et al. CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow. Blood 2004, 103:2981-2989.
    • (2004) Blood , vol.103 , pp. 2981-2989
    • Avigdor, A.1
  • 14
    • 84894478436 scopus 로고    scopus 로고
    • (in press) New nomenclature for atypical chemokine receptor. Nat. Immunol.
    • Bachelerie, F. et al. (in press) New nomenclature for atypical chemokine receptor. Nat. Immunol.
    • Bachelerie, F.1
  • 15
    • 39549122204 scopus 로고    scopus 로고
    • Essential but differential role for CXCR4 and CXCR7 in the therapeutic homing of human renal progenitor cells
    • Mazzinghi B., et al. Essential but differential role for CXCR4 and CXCR7 in the therapeutic homing of human renal progenitor cells. J. Exp. Med. 2008, 205:479-490.
    • (2008) J. Exp. Med. , vol.205 , pp. 479-490
    • Mazzinghi, B.1
  • 16
    • 0032507962 scopus 로고    scopus 로고
    • Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
    • Zou Y.R., et al. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 1998, 393:595-599.
    • (1998) Nature , vol.393 , pp. 595-599
    • Zou, Y.R.1
  • 17
    • 17044411400 scopus 로고    scopus 로고
    • The role of CXCL12 in the organ-specific process of artery formation
    • Ara T., et al. The role of CXCL12 in the organ-specific process of artery formation. Blood 2005, 105:3155-3161.
    • (2005) Blood , vol.105 , pp. 3155-3161
    • Ara, T.1
  • 18
    • 68049123542 scopus 로고    scopus 로고
    • The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature
    • Takabatake Y., et al. The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature. J. Am. Soc. Nephrol. 2009, 20:1714-1723.
    • (2009) J. Am. Soc. Nephrol. , vol.20 , pp. 1714-1723
    • Takabatake, Y.1
  • 19
    • 0034691531 scopus 로고    scopus 로고
    • A chemokine-driven positive feedback loop organizes lymphoid follicles
    • Ansel K.M., et al. A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 2000, 406:309-314.
    • (2000) Nature , vol.406 , pp. 309-314
    • Ansel, K.M.1
  • 20
    • 77951753963 scopus 로고    scopus 로고
    • CCL21 is sufficient to mediate DC migration, maturation and function in the absence of CCL19
    • Britschgi M.R., et al. CCL21 is sufficient to mediate DC migration, maturation and function in the absence of CCL19. Eur. J. Immunol. 2010, 40:1266-1271.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 1266-1271
    • Britschgi, M.R.1
  • 21
    • 0033214348 scopus 로고    scopus 로고
    • CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
    • Forster R., et al. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 1999, 99:23-33.
    • (1999) Cell , vol.99 , pp. 23-33
    • Forster, R.1
  • 22
    • 35548975191 scopus 로고    scopus 로고
    • Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells
    • Link A., et al. Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells. Nat. Immunol. 2007, 8:1255-1265.
    • (2007) Nat. Immunol. , vol.8 , pp. 1255-1265
    • Link, A.1
  • 23
    • 84887619988 scopus 로고    scopus 로고
    • Directional tissue migration through a self-generated chemokine gradient
    • Dona E., et al. Directional tissue migration through a self-generated chemokine gradient. Nature 2013, 503:285-289.
    • (2013) Nature , vol.503 , pp. 285-289
    • Dona, E.1
  • 24
    • 84862194058 scopus 로고    scopus 로고
    • Chemokines and adult bone marrow stem cells
    • Rankin S.M. Chemokines and adult bone marrow stem cells. Immunol. Lett. 2012, 145:47-54.
    • (2012) Immunol. Lett. , vol.145 , pp. 47-54
    • Rankin, S.M.1
  • 25
    • 18444389451 scopus 로고    scopus 로고
    • Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand
    • Heissig B., et al. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell 2002, 109:625-637.
    • (2002) Cell , vol.109 , pp. 625-637
    • Heissig, B.1
  • 26
    • 0033001177 scopus 로고    scopus 로고
    • Effects of CC, CXC, C, and CX3C chemokines on proliferation of myeloid progenitor cells, and insights into SDF-1-induced chemotaxis of progenitors
    • Broxmeyer H.E., et al. Effects of CC, CXC, C, and CX3C chemokines on proliferation of myeloid progenitor cells, and insights into SDF-1-induced chemotaxis of progenitors. Ann. N. Y. Acad. Sci. 1999, 872:142-163.
    • (1999) Ann. N. Y. Acad. Sci. , vol.872 , pp. 142-163
    • Broxmeyer, H.E.1
  • 27
    • 77952422757 scopus 로고    scopus 로고
    • Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex
    • Ratajczak M.Z., et al. Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex. Leukemia 2010, 24:976-985.
    • (2010) Leukemia , vol.24 , pp. 976-985
    • Ratajczak, M.Z.1
  • 28
    • 0037656291 scopus 로고    scopus 로고
    • Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease
    • Hernandez P.A., et al. Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease. Nat. Genet. 2003, 34:70-74.
    • (2003) Nat. Genet. , vol.34 , pp. 70-74
    • Hernandez, P.A.1
  • 29
    • 0142188265 scopus 로고    scopus 로고
    • Chemokines acting via CXCR2 and CXCR4 control the release of neutrophils from the bone marrow and their return following senescence
    • Martin C., et al. Chemokines acting via CXCR2 and CXCR4 control the release of neutrophils from the bone marrow and their return following senescence. Immunity 2003, 19:583-593.
    • (2003) Immunity , vol.19 , pp. 583-593
    • Martin, C.1
  • 30
    • 0032482926 scopus 로고    scopus 로고
    • Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
    • Ma Q., et al. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:9448-9453.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 9448-9453
    • Ma, Q.1
  • 31
    • 20944440068 scopus 로고    scopus 로고
    • Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist
    • Broxmeyer H.E., et al. Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist. J. Exp. Med. 2005, 201:1307-1318.
    • (2005) J. Exp. Med. , vol.201 , pp. 1307-1318
    • Broxmeyer, H.E.1
  • 32
    • 77956241246 scopus 로고    scopus 로고
    • Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling
    • Kokovay E., et al. Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling. Cell Stem Cell 2010, 7:163-173.
    • (2010) Cell Stem Cell , vol.7 , pp. 163-173
    • Kokovay, E.1
  • 33
    • 33845571563 scopus 로고    scopus 로고
    • Expression of SDF-1 and CXCR4 during reorganization of the postnatal dentate gyrus
    • Berger O., et al. Expression of SDF-1 and CXCR4 during reorganization of the postnatal dentate gyrus. Dev. Neurosci. 2007, 29:48-58.
    • (2007) Dev. Neurosci. , vol.29 , pp. 48-58
    • Berger, O.1
  • 34
    • 48549088793 scopus 로고    scopus 로고
    • The chemokine stromal cell-derived factor-1 regulates GABAergic inputs to neural progenitors in the postnatal dentate gyrus
    • Bhattacharyya B.J., et al. The chemokine stromal cell-derived factor-1 regulates GABAergic inputs to neural progenitors in the postnatal dentate gyrus. J. Neurosci. 2008, 28:6720-6730.
    • (2008) J. Neurosci. , vol.28 , pp. 6720-6730
    • Bhattacharyya, B.J.1
  • 35
    • 84866753559 scopus 로고    scopus 로고
    • Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair
    • Li M., et al. Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair. Trends Neurosci. 2012, 35:619-628.
    • (2012) Trends Neurosci. , vol.35 , pp. 619-628
    • Li, M.1
  • 36
    • 77954653333 scopus 로고    scopus 로고
    • CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination
    • Patel J.R., et al. CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:11062-11067.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 11062-11067
    • Patel, J.R.1
  • 37
    • 84876324765 scopus 로고    scopus 로고
    • CXCL12-CXCR4 signaling is required for the maintenance of mouse spermatogonial stem cells
    • Yang Q.E., et al. CXCL12-CXCR4 signaling is required for the maintenance of mouse spermatogonial stem cells. J. Cell Sci. 2013, 126:1009-1020.
    • (2013) J. Cell Sci. , vol.126 , pp. 1009-1020
    • Yang, Q.E.1
  • 38
    • 84883342660 scopus 로고    scopus 로고
    • CXCL12/CXCR4 signaling in the osteoblast regulates the mesenchymal stem cell and osteoclast lineage populations
    • Shahnazari M., et al. CXCL12/CXCR4 signaling in the osteoblast regulates the mesenchymal stem cell and osteoclast lineage populations. FASEB J. 2013, 27:3505-3513.
    • (2013) FASEB J. , vol.27 , pp. 3505-3513
    • Shahnazari, M.1
  • 39
    • 77953536520 scopus 로고    scopus 로고
    • Stromal derived factor-1 regulates bone morphogenetic protein 2-induced osteogenic differentiation of primary mesenchymal stem cells
    • Hosogane N., et al. Stromal derived factor-1 regulates bone morphogenetic protein 2-induced osteogenic differentiation of primary mesenchymal stem cells. Int. J. Biochem. Cell Biol. 2010, 42:1132-1141.
    • (2010) Int. J. Biochem. Cell Biol. , vol.42 , pp. 1132-1141
    • Hosogane, N.1
  • 40
    • 84864435399 scopus 로고    scopus 로고
    • Regulatory role of stromal cell-derived factor-1 in bone morphogenetic protein-2-induced chondrogenic differentiation in vitro
    • Guang L.G., et al. Regulatory role of stromal cell-derived factor-1 in bone morphogenetic protein-2-induced chondrogenic differentiation in vitro. Int. J. Biochem. Cell Biol. 2012, 44:1825-1833.
    • (2012) Int. J. Biochem. Cell Biol. , vol.44 , pp. 1825-1833
    • Guang, L.G.1
  • 41
    • 77953056742 scopus 로고    scopus 로고
    • Induction of myogenic differentiation by SDF-1 via CXCR4 and CXCR7 receptors
    • Melchionna R., et al. Induction of myogenic differentiation by SDF-1 via CXCR4 and CXCR7 receptors. Muscle Nerve 2010, 41:828-835.
    • (2010) Muscle Nerve , vol.41 , pp. 828-835
    • Melchionna, R.1
  • 42
    • 18844406447 scopus 로고    scopus 로고
    • Homing to hypoxia: HIF-1 as a mediator of progenitor cell recruitment to injured tissue
    • Ceradini D.J., Gurtner G.C. Homing to hypoxia: HIF-1 as a mediator of progenitor cell recruitment to injured tissue. Trends Cardiovasc. Med. 2005, 15:57-63.
    • (2005) Trends Cardiovasc. Med. , vol.15 , pp. 57-63
    • Ceradini, D.J.1    Gurtner, G.C.2
  • 43
    • 4043184065 scopus 로고    scopus 로고
    • Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
    • Ceradini D.J., et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat. Med. 2004, 10:858-864.
    • (2004) Nat. Med. , vol.10 , pp. 858-864
    • Ceradini, D.J.1
  • 44
    • 45749105047 scopus 로고    scopus 로고
    • P21Cip1 modulates arterial wound repair through the stromal cell-derived factor-1/CXCR4 axis in mice
    • Olive M., et al. p21Cip1 modulates arterial wound repair through the stromal cell-derived factor-1/CXCR4 axis in mice. J. Clin. Invest. 2008, 118:2050-2061.
    • (2008) J. Clin. Invest. , vol.118 , pp. 2050-2061
    • Olive, M.1
  • 45
    • 17744387942 scopus 로고    scopus 로고
    • Renal SDF-1 signals mobilization and homing of CXCR4-positive cells to the kidney after ischemic injury
    • Togel F., et al. Renal SDF-1 signals mobilization and homing of CXCR4-positive cells to the kidney after ischemic injury. Kidney Int. 2005, 67:1772-1784.
    • (2005) Kidney Int. , vol.67 , pp. 1772-1784
    • Togel, F.1
  • 46
    • 81855225283 scopus 로고    scopus 로고
    • Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction
    • Liehn E.A., et al. Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction. J. Am. Coll. Cardiol. 2011, 58:2415-2423.
    • (2011) J. Am. Coll. Cardiol. , vol.58 , pp. 2415-2423
    • Liehn, E.A.1
  • 47
    • 9344255481 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury
    • Abbott J.D., et al. Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury. Circulation 2004, 110:3300-3305.
    • (2004) Circulation , vol.110 , pp. 3300-3305
    • Abbott, J.D.1
  • 48
    • 33644663839 scopus 로고    scopus 로고
    • Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease
    • Walter D.H., et al. Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease. Circ. Res. 2005, 97:1142-1151.
    • (2005) Circ. Res. , vol.97 , pp. 1142-1151
    • Walter, D.H.1
  • 49
    • 20244375128 scopus 로고    scopus 로고
    • SDF-1alpha/CXCR4 axis is instrumental in neointimal hyperplasia and recruitment of smooth muscle progenitor cells
    • Zernecke A., et al. SDF-1alpha/CXCR4 axis is instrumental in neointimal hyperplasia and recruitment of smooth muscle progenitor cells. Circ. Res. 2005, 96:784-791.
    • (2005) Circ. Res. , vol.96 , pp. 784-791
    • Zernecke, A.1
  • 50
    • 79951854922 scopus 로고    scopus 로고
    • Inhibition of stromal cell-derived factor-1alpha further impairs diabetic wound healing
    • Bermudez D.M., et al. Inhibition of stromal cell-derived factor-1alpha further impairs diabetic wound healing. J. Vasc. Surg. 2011, 53:774-784.
    • (2011) J. Vasc. Surg. , vol.53 , pp. 774-784
    • Bermudez, D.M.1
  • 51
    • 34248213008 scopus 로고    scopus 로고
    • Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1 alpha
    • Gallagher K.A., et al. Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1 alpha. J. Clin. Invest. 2007, 117:1249-1259.
    • (2007) J. Clin. Invest. , vol.117 , pp. 1249-1259
    • Gallagher, K.A.1
  • 52
    • 77953747577 scopus 로고    scopus 로고
    • Continuous delivery of stromal cell-derived factor-1 from alginate scaffolds accelerates wound healing
    • Rabbany S.Y., et al. Continuous delivery of stromal cell-derived factor-1 from alginate scaffolds accelerates wound healing. Cell Transplant. 2010, 19:399-408.
    • (2010) Cell Transplant. , vol.19 , pp. 399-408
    • Rabbany, S.Y.1
  • 53
    • 33947386667 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1 promotes angiogenesis via a heme oxygenase 1-dependent mechanism
    • Deshane J., et al. Stromal cell-derived factor 1 promotes angiogenesis via a heme oxygenase 1-dependent mechanism. J. Exp. Med. 2007, 204:605-618.
    • (2007) J. Exp. Med. , vol.204 , pp. 605-618
    • Deshane, J.1
  • 54
    • 33846019216 scopus 로고    scopus 로고
    • CTACK/CCL27 accelerates skin regeneration via accumulation of bone marrow-derived keratinocytes
    • Inokuma D., et al. CTACK/CCL27 accelerates skin regeneration via accumulation of bone marrow-derived keratinocytes. Stem Cells 2006, 24:2810-2816.
    • (2006) Stem Cells , vol.24 , pp. 2810-2816
    • Inokuma, D.1
  • 55
    • 31144435893 scopus 로고    scopus 로고
    • Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injury
    • Gomperts B.N., et al. Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injury. J. Immunol. 2006, 176:1916-1927.
    • (2006) J. Immunol. , vol.176 , pp. 1916-1927
    • Gomperts, B.N.1
  • 56
    • 79959760786 scopus 로고    scopus 로고
    • Targeted intestinal epithelial deletion of the chemokine receptor CXCR4 reveals important roles for extracellular-regulated kinase-1/2 in restitution
    • Zimmerman N.P., et al. Targeted intestinal epithelial deletion of the chemokine receptor CXCR4 reveals important roles for extracellular-regulated kinase-1/2 in restitution. Lab. Invest. 2011, 91:1040-1055.
    • (2011) Lab. Invest. , vol.91 , pp. 1040-1055
    • Zimmerman, N.P.1
  • 57
    • 84879095350 scopus 로고    scopus 로고
    • CXCL12/CXCR4 axis promotes mesenchymal stem cell mobilization to burn wounds and contributes to wound repair
    • Hu C., et al. CXCL12/CXCR4 axis promotes mesenchymal stem cell mobilization to burn wounds and contributes to wound repair. J. Surg. Res. 2013, 183:427-434.
    • (2013) J. Surg. Res. , vol.183 , pp. 427-434
    • Hu, C.1
  • 58
    • 0035877019 scopus 로고    scopus 로고
    • Peripheral blood fibrocytes: differentiation pathway and migration to wound sites
    • Abe R., et al. Peripheral blood fibrocytes: differentiation pathway and migration to wound sites. J. Immunol. 2001, 166:7556-7562.
    • (2001) J. Immunol. , vol.166 , pp. 7556-7562
    • Abe, R.1
  • 59
    • 84879693711 scopus 로고    scopus 로고
    • Fibrocytes develop outside the kidney but contribute to renal fibrosis in a mouse model
    • Reich B., et al. Fibrocytes develop outside the kidney but contribute to renal fibrosis in a mouse model. Kidney Int. 2013, 84:78-89.
    • (2013) Kidney Int. , vol.84 , pp. 78-89
    • Reich, B.1
  • 60
    • 61649090805 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model
    • Kitaori T., et al. Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model. Arthritis Rheum. 2009, 60:813-823.
    • (2009) Arthritis Rheum. , vol.60 , pp. 813-823
    • Kitaori, T.1
  • 61
    • 84862186837 scopus 로고    scopus 로고
    • Role of lymphoid chemokines in the development of functional ectopic lymphoid structures in rheumatic autoimmune diseases
    • Corsiero E., et al. Role of lymphoid chemokines in the development of functional ectopic lymphoid structures in rheumatic autoimmune diseases. Immunol. Lett. 2012, 145:62-67.
    • (2012) Immunol. Lett. , vol.145 , pp. 62-67
    • Corsiero, E.1
  • 62
    • 0037443781 scopus 로고    scopus 로고
    • Role of the chemokine stromal cell-derived factor 1 in autoantibody production and nephritis in murine lupus
    • Balabanian K., et al. Role of the chemokine stromal cell-derived factor 1 in autoantibody production and nephritis in murine lupus. J. Immunol. 2003, 170:3392-3400.
    • (2003) J. Immunol. , vol.170 , pp. 3392-3400
    • Balabanian, K.1
  • 63
    • 79951694551 scopus 로고    scopus 로고
    • CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity
    • Cruz-Orengo L., et al. CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity. J. Exp. Med. 2011, 208:327-339.
    • (2011) J. Exp. Med. , vol.208 , pp. 327-339
    • Cruz-Orengo, L.1
  • 64
    • 84864374820 scopus 로고    scopus 로고
    • Attenuation of osteoarthritis via blockade of the SDF-1/CXCR4 signaling pathway
    • Wei F., et al. Attenuation of osteoarthritis via blockade of the SDF-1/CXCR4 signaling pathway. Arthritis Res. Ther. 2012, 14:R177.
    • (2012) Arthritis Res. Ther. , vol.14
    • Wei, F.1
  • 65
    • 69749122514 scopus 로고    scopus 로고
    • CXCR4 but not CXCR7 is mainly implicated in ocular leukocyte trafficking during ovalbumin-induced acute uveitis
    • Zhang Z., et al. CXCR4 but not CXCR7 is mainly implicated in ocular leukocyte trafficking during ovalbumin-induced acute uveitis. Exp. Eye Res. 2009, 89:522-531.
    • (2009) Exp. Eye Res. , vol.89 , pp. 522-531
    • Zhang, Z.1
  • 66
    • 84859892389 scopus 로고    scopus 로고
    • CXCL12 in control of neuroinflammation
    • Momcilovic M., et al. CXCL12 in control of neuroinflammation. Immunol. Res. 2012, 52:53-63.
    • (2012) Immunol. Res. , vol.52 , pp. 53-63
    • Momcilovic, M.1
  • 67
    • 33748448816 scopus 로고    scopus 로고
    • Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice
    • Ding M., et al. Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice. Nat. Med. 2006, 12:1081-1087.
    • (2006) Nat. Med. , vol.12 , pp. 1081-1087
    • Ding, M.1
  • 68
    • 4043055316 scopus 로고    scopus 로고
    • Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis
    • Phillips R.J., et al. Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis. J. Clin. Invest. 2004, 114:438-446.
    • (2004) J. Clin. Invest. , vol.114 , pp. 438-446
    • Phillips, R.J.1
  • 69
    • 85047690920 scopus 로고    scopus 로고
    • SDF-1 is both necessary and sufficient to promote proliferative retinopathy
    • Butler J.M., et al. SDF-1 is both necessary and sufficient to promote proliferative retinopathy. J. Clin. Invest. 2005, 115:86-93.
    • (2005) J. Clin. Invest. , vol.115 , pp. 86-93
    • Butler, J.M.1
  • 70
    • 80052435113 scopus 로고    scopus 로고
    • Dual blockade of the homeostatic chemokine CXCL12 and the proinflammatory chemokine CCL2 has additive protective effects on diabetic kidney disease
    • Darisipudi M.N., et al. Dual blockade of the homeostatic chemokine CXCL12 and the proinflammatory chemokine CCL2 has additive protective effects on diabetic kidney disease. Am. J. Pathol. 2011, 179:116-124.
    • (2011) Am. J. Pathol. , vol.179 , pp. 116-124
    • Darisipudi, M.N.1
  • 71
    • 76149112291 scopus 로고    scopus 로고
    • Human nephrosclerosis triggers a hypoxia-related glomerulopathy
    • Neusser M.A., et al. Human nephrosclerosis triggers a hypoxia-related glomerulopathy. Am. J. Pathol. 2010, 176:594-607.
    • (2010) Am. J. Pathol. , vol.176 , pp. 594-607
    • Neusser, M.A.1
  • 72
    • 47949096781 scopus 로고    scopus 로고
    • Cancer-related inflammation
    • Mantovani A., et al. Cancer-related inflammation. Nature 2008, 454:436-444.
    • (2008) Nature , vol.454 , pp. 436-444
    • Mantovani, A.1
  • 73
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • Hermann P.C., et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 2007, 1:313-323.
    • (2007) Cell Stem Cell , vol.1 , pp. 313-323
    • Hermann, P.C.1
  • 74
    • 3042616145 scopus 로고    scopus 로고
    • Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4
    • Liang Z., et al. Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4. Cancer Res. 2004, 64:4302-4308.
    • (2004) Cancer Res. , vol.64 , pp. 4302-4308
    • Liang, Z.1
  • 75
    • 77953348723 scopus 로고    scopus 로고
    • CXCR4 and cancer
    • Furusato B., et al. CXCR4 and cancer. Pathol. Int. 2010, 60:497-505.
    • (2010) Pathol. Int. , vol.60 , pp. 497-505
    • Furusato, B.1
  • 76
    • 0035282432 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in breast cancer metastasis
    • Muller A., et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001, 410:50-56.
    • (2001) Nature , vol.410 , pp. 50-56
    • Muller, A.1
  • 77
    • 33846682591 scopus 로고    scopus 로고
    • The inflammatory cytokine tumor necrosis factor-alpha generates an autocrine tumor-promoting network in epithelial ovarian cancer cells
    • Kulbe H., et al. The inflammatory cytokine tumor necrosis factor-alpha generates an autocrine tumor-promoting network in epithelial ovarian cancer cells. Cancer Res. 2007, 67:585-592.
    • (2007) Cancer Res. , vol.67 , pp. 585-592
    • Kulbe, H.1
  • 78
    • 0141828145 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL
    • Staller P., et al. Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL. Nature 2003, 425:307-311.
    • (2003) Nature , vol.425 , pp. 307-311
    • Staller, P.1
  • 79
    • 84872080485 scopus 로고    scopus 로고
    • Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer
    • Vanharanta S., et al. Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer. Nat. Med. 2013, 19:50-56.
    • (2013) Nat. Med. , vol.19 , pp. 50-56
    • Vanharanta, S.1
  • 80
    • 84870510405 scopus 로고    scopus 로고
    • Sequential genetic change at the TP53 and chemokine receptor CXCR4 locus during transformation of human ovarian surface epithelium
    • Archibald K.M., et al. Sequential genetic change at the TP53 and chemokine receptor CXCR4 locus during transformation of human ovarian surface epithelium. Oncogene 2012, 31:4987-4995.
    • (2012) Oncogene , vol.31 , pp. 4987-4995
    • Archibald, K.M.1
  • 81
    • 0037108923 scopus 로고    scopus 로고
    • Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer
    • Scotton C.J., et al. Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer. Cancer Res. 2002, 62:5930-5938.
    • (2002) Cancer Res. , vol.62 , pp. 5930-5938
    • Scotton, C.J.1
  • 82
    • 0037447318 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt
    • Barbero S., et al. Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt. Cancer Res. 2003, 63:1969-1974.
    • (2003) Cancer Res. , vol.63 , pp. 1969-1974
    • Barbero, S.1
  • 83
    • 33646426383 scopus 로고    scopus 로고
    • Human melanoma metastases express functional CXCR4
    • Scala S., et al. Human melanoma metastases express functional CXCR4. Clin. Cancer Res. 2006, 12:2427-2433.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 2427-2433
    • Scala, S.1
  • 84
    • 36049020021 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 enhances motility and integrin up-regulation through CXCR4, ERK and NF-kappaB-dependent pathway in human lung cancer cells
    • Huang Y.C., et al. Stromal cell-derived factor-1 enhances motility and integrin up-regulation through CXCR4, ERK and NF-kappaB-dependent pathway in human lung cancer cells. Biochem. Pharmacol. 2007, 74:1702-1712.
    • (2007) Biochem. Pharmacol. , vol.74 , pp. 1702-1712
    • Huang, Y.C.1
  • 85
    • 0033485625 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells
    • Burger J.A., et al. Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells. Blood 1999, 94:3658-3667.
    • (1999) Blood , vol.94 , pp. 3658-3667
    • Burger, J.A.1
  • 86
    • 4644300589 scopus 로고    scopus 로고
    • Correlation between CXCR4 and homing or engraftment of acute myelogenous leukemia
    • Monaco G., et al. Correlation between CXCR4 and homing or engraftment of acute myelogenous leukemia. Cancer Res. 2004, 64:6832-6833.
    • (2004) Cancer Res. , vol.64 , pp. 6832-6833
    • Monaco, G.1
  • 87
    • 84874787432 scopus 로고    scopus 로고
    • CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors
    • Mo W., et al. CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell 2013, 152:1077-1090.
    • (2013) Cell , vol.152 , pp. 1077-1090
    • Mo, W.1
  • 88
    • 84878529330 scopus 로고    scopus 로고
    • CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia
    • Chen Y., et al. CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia. J. Clin. Invest. 2013, 123:2395-2407.
    • (2013) J. Clin. Invest. , vol.123 , pp. 2395-2407
    • Chen, Y.1
  • 89
    • 77952231121 scopus 로고    scopus 로고
    • Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21
    • Shields J.D., et al. Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21. Science 2010, 328:749-752.
    • (2010) Science , vol.328 , pp. 749-752
    • Shields, J.D.1
  • 90
    • 67649249962 scopus 로고    scopus 로고
    • CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia
    • Buonamici S., et al. CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia. Nature 2009, 459:1000-1004.
    • (2009) Nature , vol.459 , pp. 1000-1004
    • Buonamici, S.1
  • 91
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • Balkwill F. Cancer and the chemokine network. Nat. Rev. Cancer 2004, 4:540-550.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 540-550
    • Balkwill, F.1
  • 92
    • 34748820033 scopus 로고    scopus 로고
    • Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response
    • Koizumi K., et al. Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response. Cancer Sci. 2007, 98:1652-1658.
    • (2007) Cancer Sci. , vol.98 , pp. 1652-1658
    • Koizumi, K.1
  • 93
    • 27644562737 scopus 로고    scopus 로고
    • Role of CXCR4 chemokine receptor blockade using AMD3100 for mobilization of autologous hematopoietic progenitor cells
    • Flomenberg N., et al. Role of CXCR4 chemokine receptor blockade using AMD3100 for mobilization of autologous hematopoietic progenitor cells. Acta Haematol. 2005, 114:198-205.
    • (2005) Acta Haematol. , vol.114 , pp. 198-205
    • Flomenberg, N.1
  • 94
    • 84860349448 scopus 로고    scopus 로고
    • A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia
    • Uy G.L., et al. A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia. Blood 2012, 119:3917-3924.
    • (2012) Blood , vol.119 , pp. 3917-3924
    • Uy, G.L.1
  • 95
    • 80855156712 scopus 로고    scopus 로고
    • The CXCR4 antagonist plerixafor is a potential therapy for myelokathexis, WHIM syndrome
    • Dale D.C., et al. The CXCR4 antagonist plerixafor is a potential therapy for myelokathexis, WHIM syndrome. Blood 2011, 118:4963-4966.
    • (2011) Blood , vol.118 , pp. 4963-4966
    • Dale, D.C.1
  • 96
    • 13344278012 scopus 로고    scopus 로고
    • HCC-1, a novel chemokine from human plasma
    • Schulz-Knappe P., et al. HCC-1, a novel chemokine from human plasma. J. Exp. Med. 1996, 183:295-299.
    • (1996) J. Exp. Med. , vol.183 , pp. 295-299
    • Schulz-Knappe, P.1
  • 97
    • 9144259213 scopus 로고    scopus 로고
    • CCL16 activates an angiogenic program in vascular endothelial cells
    • Strasly M., et al. CCL16 activates an angiogenic program in vascular endothelial cells. Blood 2004, 103:40-49.
    • (2004) Blood , vol.103 , pp. 40-49
    • Strasly, M.1
  • 98
    • 84872058734 scopus 로고    scopus 로고
    • CCX-CKR deficiency alters thymic stroma impairing thymocyte development and promoting autoimmunity
    • Bunting M.D., et al. CCX-CKR deficiency alters thymic stroma impairing thymocyte development and promoting autoimmunity. Blood 2013, 121:118-128.
    • (2013) Blood , vol.121 , pp. 118-128
    • Bunting, M.D.1
  • 99
    • 58749117434 scopus 로고    scopus 로고
    • An indispensable role for the chemokine receptor CCR10 in IgA antibody-secreting cell accumulation
    • Morteau O., et al. An indispensable role for the chemokine receptor CCR10 in IgA antibody-secreting cell accumulation. J. Immunol. 2008, 181:6309-6315.
    • (2008) J. Immunol. , vol.181 , pp. 6309-6315
    • Morteau, O.1
  • 100
    • 34250162780 scopus 로고    scopus 로고
    • Impaired accumulation of antigen-specific CD8 lymphocytes in chemokine CCL25-deficient intestinal epithelium and lamina propria
    • Wurbel M.A., et al. Impaired accumulation of antigen-specific CD8 lymphocytes in chemokine CCL25-deficient intestinal epithelium and lamina propria. J. Immunol. 2007, 178:7598-7606.
    • (2007) J. Immunol. , vol.178 , pp. 7598-7606
    • Wurbel, M.A.1
  • 101
    • 3843072270 scopus 로고    scopus 로고
    • Transgenic mice studies demonstrate a role for platelet factor 4 in thrombosis: dissociation between anticoagulant and antithrombotic effect of heparin
    • Eslin D.E., et al. Transgenic mice studies demonstrate a role for platelet factor 4 in thrombosis: dissociation between anticoagulant and antithrombotic effect of heparin. Blood 2004, 104:3173-3180.
    • (2004) Blood , vol.104 , pp. 3173-3180
    • Eslin, D.E.1
  • 102
    • 0029758113 scopus 로고    scopus 로고
    • Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
    • Nagasawa T., et al. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 1996, 382:635-638.
    • (1996) Nature , vol.382 , pp. 635-638
    • Nagasawa, T.1
  • 103
    • 0037087478 scopus 로고    scopus 로고
    • A role for CCR9 in T lymphocyte development and migration
    • Uehara S., et al. A role for CCR9 in T lymphocyte development and migration. J. Immunol. 2002, 168:2811-2819.
    • (2002) J. Immunol. , vol.168 , pp. 2811-2819
    • Uehara, S.1
  • 104
    • 35548996783 scopus 로고    scopus 로고
    • Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7
    • Sierro F., et al. Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:14759-14764.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 14759-14764
    • Sierro, F.1
  • 105
    • 3142559469 scopus 로고    scopus 로고
    • Homeostatic chemokines drive migration of malignant B cells in patients with non-Hodgkin lymphomas
    • Trentin L., et al. Homeostatic chemokines drive migration of malignant B cells in patients with non-Hodgkin lymphomas. Blood 2004, 104:502-508.
    • (2004) Blood , vol.104 , pp. 502-508
    • Trentin, L.1
  • 106
    • 80052734649 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1 (SDF-1) and its receptor CXCR4 in the formation of postburn hypertrophic scar (HTS)
    • Ding J., et al. Stromal cell-derived factor 1 (SDF-1) and its receptor CXCR4 in the formation of postburn hypertrophic scar (HTS). Wound Repair Regen. 2011, 19:568-578.
    • (2011) Wound Repair Regen. , vol.19 , pp. 568-578
    • Ding, J.1


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