Stromal cell-derived factor-1 enhances motility and integrin up-regulation through CXCR4, ERK and NF-κB-dependent pathway in human lung cancer cells

Biochemical Pharmacology

Volumn 74, Issue 12, 2007, Pages 1702-1712

  Huang, Yi Chia ^a   Hsiao, Yu Chun ^a   Chen, Ying Ju ^a   Wei, Ying Ying ^a   Lai, Tzu Hsu ^b   Tang, Chih Hsin ^b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

CXCR4; Integrin; Lung cancer; Migration; SDF

Indexed keywords

1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; PYRROLIDINE DITHIOCARBAMATE; SMALL INTERFERING RNA; STROMAL CELL DERIVED FACTOR 1; SYNAPTOTAGMIN I; TOSYLPHENYLALANYL CHLOROMETHYL KETONE;

ARTICLE; CANCER CELL CULTURE; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LUNG CANCER; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION;

BASE SEQUENCE; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOKINE CXCL12; DNA PRIMERS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INTEGRINS; LUNG NEOPLASMS; NF-KAPPA B; PHOSPHORYLATION; PROTEASE INHIBITORS; RECEPTORS, CXCR4; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 36049020021     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.08.025     Document Type: Article

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