Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice

Nature Medicine

Volumn 12, Issue 9, 2006, Pages 1081-1087

  Ding, Mei ^a,b   Cui, Shiying ^a   Li, Chengjin ^a   Jothy, Serge ^c   Haase, Volker ^d   Steer, Brent M ^c   Marsden, Philip A ^c   Pippin, Jeffrey ^e   Shankland, Stuart ^e   Rastaldi, Maria Pia ^f   Cohen, Clemens D ^g   Kretzler, Matthias ^g,h   Quaggin, Susan E ^a,b,c  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c ST MICHAEL'S HOSPITAL   (Canada)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^f SAN CARLO BORROMEO HOSPITAL   (Italy)

^g UNIVERSITY OF MUNICH   (Germany)

^h UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; TUMOR SUPPRESSOR PROTEIN; VON HIPPEL LINDAU PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOPSY; CELL PROLIFERATION; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION; GENOTYPE; GLOMERULONEPHRITIS; GLOMERULOPATHY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY FUNCTION; MOUSE; NONHUMAN; PATHOGENESIS; PODOCYTE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL PROLIFERATION; GENE EXPRESSION PROFILING; GLOMERULONEPHRITIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KIDNEY GLOMERULUS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PODOCYTES; RECEPTORS, CXCR4; UP-REGULATION; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

ANIMALIA; MUS MUSCULUS;

EID: 33748448816     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1460     Document Type: Article

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