-
1
-
-
0004155427
-
-
4th Ed.; W.H. Freeman and Company: New York, NY, USA
-
Stryer, L. Biochemistry, 4th Ed.; W.H. Freeman and Company: New York, NY, USA, 1995.
-
(1995)
Biochemistry
-
-
Stryer, L.1
-
2
-
-
84855620601
-
-
John Wiley & Sons: New York, NY, USA
-
12; John Wiley & Sons: New York, NY, USA, 1982; Volume 1.
-
(1982)
12;
, vol.1
-
-
Dolphin, D.1
-
3
-
-
84855620601
-
-
John Wiley & Sons: New York, NY, USA
-
12; John Wiley & Sons: New York, NY, USA, 1982; Volume 2.
-
(1982)
12
, vol.2
-
-
Dolphin, D.1
-
4
-
-
33846687336
-
-
Wiley-Interscience: New York, NY, USA
-
12; Wiley-Interscience: New York, NY, USA, 1999.
-
(1999)
12
-
-
Banerjee, R.1
-
8
-
-
33748632647
-
Free radical mechanisms in enzymology
-
Frey, P.A.; Hegeman, A.D.; Reed, G.H. Free radical mechanisms in enzymology. Chem. Rev. 2006, 106, 3302-3316.
-
(2006)
Chem. Rev.
, vol.106
, pp. 3302-3316
-
-
Frey, P.A.1
Hegeman, A.D.2
Reed, G.H.3
-
10
-
-
0037899473
-
12-dependent mutases
-
12-dependent mutases. Chem. Rev. 2003, 103, 2083-2094.
-
(2003)
Chem. Rev.
, vol.103
, pp. 2083-2094
-
-
Banerjee, R.1
-
11
-
-
0037560995
-
12-dependent isomerization (eliminating) reactions
-
12-dependent isomerization (eliminating) reactions. Chem. Rev. 2003, 103, 2095-2127.
-
(2003)
Chem. Rev.
, vol.103
, pp. 2095-2127
-
-
Toraya, T.1
-
12
-
-
80054699132
-
Pyridoxal Phosphate Enzymology
-
In; Toney, M.D., Ed.; Elsevier: Miamisburg, OH, USA
-
Pyridoxal Phosphate Enzymology. In Biochimica et Biophysica Acta; Toney, M.D., Ed.; Elsevier: Miamisburg, OH, USA, 2011; Volume 1814, pp. 1405-1608.
-
(2011)
Biochimica et Biophysica Acta
, vol.1814
, pp. 1405-1608
-
-
-
15
-
-
80053318335
-
Mechanism of formation of the internal aldimine in pyridoxal 5'-phosphate-dependent enzymes
-
Oliveira, E.F.; Cerqueira, N.M.F.S.A.; Fernandes, P.A.; Ramos, M.J. Mechanism of formation of the internal aldimine in pyridoxal 5'-phosphate-dependent enzymes. J. Am. Chem. Soc. 2011, 133, 15496-15505.
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 15496-15505
-
-
Oliveira, E.F.1
Cerqueira, N.M.F.S.A.2
Fernandes, P.A.3
Ramos, M.J.4
-
16
-
-
3943113663
-
Pyridoxal phosphate enzymes: Mechanistic, structural, and evolutionary considerations
-
Eliot, A.C.; Kirsch, J.F. Pyridoxal phosphate enzymes: Mechanistic, structural, and evolutionary considerations. Annu. Rev. Biochem. 2004, 73, 383-415.
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 383-415
-
-
Eliot, A.C.1
Kirsch, J.F.2
-
21
-
-
84866981232
-
Hydrogen bonds guide the short-lived 5'-deoxyadenosyl radical to the place of action
-
Buckel, W.; Friedrich, P.; Golding, B.T. Hydrogen bonds guide the short-lived 5'-deoxyadenosyl radical to the place of action. Angew. Chem. Int. Ed. 2012, 51, 9974-9976.
-
(2012)
Angew. Chem. Int. Ed.
, vol.51
, pp. 9974-9976
-
-
Buckel, W.1
Friedrich, P.2
Golding, B.T.3
-
23
-
-
77954628691
-
Cobalamin coenzymes in enzymology
-
In Mander, L., Lui, H.-W., Eds.; Elsevier: Oxford, UK
-
Frey, P.A. Cobalamin coenzymes in enzymology. In Comprehensive Natural Products II Chemistry and Biology; Mander, L., Lui, H.-W., Eds.; Elsevier: Oxford, UK, 2010; Volume 7, pp. 501-546.
-
(2010)
Comprehensive Natural Products II Chemistry and Biology
, vol.7
, pp. 501-546
-
-
Frey, P.A.1
-
24
-
-
80054696193
-
Pyridoxal-5'-phosphate as the catalyst for radical isomerization in reactions of PLP-dependent aminomutases
-
Frey, P.A.; Reed, G.H. Pyridoxal-5'-phosphate as the catalyst for radical isomerization in reactions of PLP-dependent aminomutases. Biochim. Biophys. Acta 2011, 1814, 1548-1557.
-
(2011)
Biochim. Biophys. Acta
, vol.1814
, pp. 1548-1557
-
-
Frey, P.A.1
Reed, G.H.2
-
26
-
-
0000944732
-
Amino Mutases
-
In Dolphin, D., Ed.; John Wiley & Sons: New York, NY, USA
-
12; Dolphin, D., Ed.; John Wiley & Sons: New York, NY, USA, 1982; Volume 2, pp. 203-232.
-
(1982)
12
, vol.2
, pp. 203-232
-
-
Baker, J.J.1
Stadtman, T.C.2
-
27
-
-
84906290989
-
Lysine metabolism by Clostridia
-
Stadtman, T.C. Lysine metabolism by Clostridia. Adv. Enzymol. 1973, 38, 413-448.
-
(1973)
Adv. Enzymol.
, vol.38
, pp. 413-448
-
-
Stadtman, T.C.1
-
28
-
-
0014937539
-
12-coenzyme-dependent D-α-lysine mutase complex from Clostridium sticklandii
-
12-coenzyme-dependent D-α-lysine mutase complex from Clostridium sticklandii. Biochemistry 1970, 9, 4890-4900.
-
(1970)
Biochemistry
, vol.9
, pp. 4890-4900
-
-
Morley, C.G.D.1
Stadtman, T.C.2
-
30
-
-
0015507332
-
12 coenzyme-dependent D-α-lysine mutase reaction
-
12 coenzyme-dependent D-α-lysine mutase reaction. Biochemistry 1972, 11, 600-605.
-
(1972)
Biochemistry
, vol.11
, pp. 600-605
-
-
Morley, C.G.D.1
Stadtman, T.C.2
-
32
-
-
0343379516
-
Aminomutases
-
In Banerjee, R., Ed.; Wiley: New York, NY, USA
-
12; Banerjee, R., Ed.; Wiley: New York, NY, USA, 1999; pp. 835-857.
-
(1999)
12
, pp. 835-857
-
-
Frey, P.A.1
Chang, C.H.2
-
33
-
-
0014712064
-
2,4-Diaminovaleric acid: An intermediate in the anaerobic oxidation of ornithine by Clostridium sticklandii
-
Dyer, J.K.; Costilow, R.N. 2,4-Diaminovaleric acid: An intermediate in the anaerobic oxidation of ornithine by Clostridium sticklandii. J. Bacteriol. 1970, 101, 77-83.
-
(1970)
J. Bacteriol.
, vol.101
, pp. 77-83
-
-
Dyer, J.K.1
Costilow, R.N.2
-
34
-
-
0014962941
-
12 coenzyme, pyridoxal phosphate, and pyridine nucleotide
-
12 coenzyme, pyridoxal phosphate, and pyridine nucleotide. J. Biol. Chem. 1970, 245, 5914-5926.
-
(1970)
J. Biol. Chem.
, vol.245
, pp. 5914-5926
-
-
Tsuda, Y.1
Friedmann, H.C.2
-
35
-
-
0015828231
-
12 dependent D-α-ornithine 5,4-aminomutase
-
12 dependent D-α-ornithine 5,4-aminomutase. Biochemistry 1973, 12, 2597-2604.
-
(1973)
Biochemistry
, vol.12
, pp. 2597-2604
-
-
Somack, R.1
Costilow, R.N.2
-
36
-
-
0034614383
-
Cloning, sequencing, heterologous expression, purification, and characterization of adenosylcobalamin-dependent D-lysine 5,6-aminomutase from Clostridium sticklandii
-
Chang, C.H.; Frey, P.A. Cloning, sequencing, heterologous expression, purification, and characterization of adenosylcobalamin-dependent D-lysine 5,6-aminomutase from Clostridium sticklandii. J. Biol. Chem. 2000, 275, 106-114.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 106-114
-
-
Chang, C.H.1
Frey, P.A.2
-
37
-
-
0035340231
-
Electron transfer in the substrate-dependent suicide inactivation of lysine 5,6-aminomutase
-
Tang, K.H.; Chang, C.H.; Frey, P.A. Electron transfer in the substrate-dependent suicide inactivation of lysine 5,6-aminomutase. Biochemistry 2001, 40, 5190-5199.
-
(2001)
Biochemistry
, vol.40
, pp. 5190-5199
-
-
Tang, K.H.1
Chang, C.H.2
Frey, P.A.3
-
38
-
-
0037046994
-
Identification of a novel pyridoxal 5'-phosphate binding site in adenosylcobalamin-dependent lysine 5,6-aminomutase from Porphyromonas gingivalis
-
Tang, K.H.; Harms, A.; Frey, P.A. Identification of a novel pyridoxal 5'-phosphate binding site in adenosylcobalamin-dependent lysine 5,6-aminomutase from Porphyromonas gingivalis. Biochemistry 2002, 41, 8767-8776.
-
(2002)
Biochemistry
, vol.41
, pp. 8767-8776
-
-
Tang, K.H.1
Harms, A.2
Frey, P.A.3
-
39
-
-
0035976954
-
Cloning, sequencing, heterologous expression, purification, and characterization of adenosylcobalamin-dependent D-ornithine aminomutase from Clostridium sticklandii
-
Chen, H.P.; Wu, S.H.; Lin, Y.L.; Chen, C.M.; Tsay, S.S. Cloning, sequencing, heterologous expression, purification, and characterization of adenosylcobalamin-dependent D-ornithine aminomutase from Clostridium sticklandii. J. Biol. Chem. 2001, 276, 44744-44750.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44744-44750
-
-
Chen, H.P.1
Wu, S.H.2
Lin, Y.L.3
Chen, C.M.4
Tsay, S.S.5
-
41
-
-
34547477100
-
The S subunit of D-ornithine aminomutase from Clostridium sticklandii is responsible for the allosteric regulation in D-α-lysine aminomutase
-
Tseng, C.H.; Yang, C.H.; Lin, H.J.; Wu, C.H.; Chen, H.P. The S subunit of D-ornithine aminomutase from Clostridium sticklandii is responsible for the allosteric regulation in D-α-lysine aminomutase. FEMS Microbiol. Lett. 2007, 274, 148-153.
-
(2007)
FEMS Microbiol. Lett.
, vol.274
, pp. 148-153
-
-
Tseng, C.H.1
Yang, C.H.2
Lin, H.J.3
Wu, C.H.4
Chen, H.P.5
-
42
-
-
0141790414
-
Kinetic and biochemical analysis of the mechanism of action of lysine 5,6-aminomutase
-
Tang, K.-H.; Casarez, A.D.; Wu, W.; Frey, P.A. Kinetic and biochemical analysis of the mechanism of action of lysine 5,6-aminomutase. Arch. Biochem. Biophys. 2003, 418, 49-54.
-
(2003)
Arch. Biochem. Biophys.
, vol.418
, pp. 49-54
-
-
Tang, K.-H.1
Casarez, A.D.2
Wu, W.3
Frey, P.A.4
-
43
-
-
84873345184
-
Mutagenesis of a conserved glutamate reveals the contribution of electrostatic energy to adenosylcobalamin Co-C bond homolysis in ornithine 4,5-aminomutase and methylmalonyl-CoA mutase
-
Makins, C.; Pickering, A.V.; Mariani, C.; Wolthers, K.R. Mutagenesis of a conserved glutamate reveals the contribution of electrostatic energy to adenosylcobalamin Co-C bond homolysis in ornithine 4,5-aminomutase and methylmalonyl-CoA mutase. Biochemistry 2013, 52, 878-888.
-
(2013)
Biochemistry
, vol.52
, pp. 878-888
-
-
Makins, C.1
Pickering, A.V.2
Mariani, C.3
Wolthers, K.R.4
-
44
-
-
8644265127
-
A locking mechanism preventing radical damage in the absence of substrate, as revealed by the X-ray structure of lysine 5,6-aminomutase
-
Berkovitch, F.; Behshad, E.; Tang, K.-H.; Enns, E.A.; Frey, P.A.; Drennan, C.L. A locking mechanism preventing radical damage in the absence of substrate, as revealed by the X-ray structure of lysine 5,6-aminomutase. Proc. Natl. Acad. Sci. USA 2004, 101, 15870-15875.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15870-15875
-
-
Berkovitch, F.1
Behshad, E.2
Tang, K.-H.3
Enns, E.A.4
Frey, P.A.5
Drennan, C.L.6
-
45
-
-
77951581676
-
Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase
-
Wolthers, K.R.; Levy, C.; Scrutton, N.S.; Leys, D. Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J. Biol. Chem. 2010, 285, 13942-13950.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 13942-13950
-
-
Wolthers, K.R.1
Levy, C.2
Scrutton, N.S.3
Leys, D.4
-
49
-
-
0033548547
-
Binding of cob (II) alamin to the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii-Identification of dimethylbenzimidazole as the axial ligand
-
Lawrence, C.C.; Gerfen, G.J.; Samano, V.; Nitsche, R.; Robins, M.J.; Retey, J.; Stubbe, J. Binding of cob (II) alamin to the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii-Identification of dimethylbenzimidazole as the axial ligand. J. Biol. Chem. 1999, 274, 7039-7042.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7039-7042
-
-
Lawrence, C.C.1
Gerfen, G.J.2
Samano, V.3
Nitsche, R.4
Robins, M.J.5
Retey, J.6
Stubbe, J.7
-
51
-
-
0030584657
-
12 radicals are generated: The crystal structure of methylmalonyl-coenzyme A mutase at 2 Å resolution
-
12 radicals are generated: The crystal structure of methylmalonyl-coenzyme A mutase at 2 Å resolution. Structure 1996, 4, 339-350.
-
(1996)
Structure
, vol.4
, pp. 339-350
-
-
Mancia, F.1
Keep, N.H.2
Nakagawa, A.3
Leadlay, P.F.4
McSweeney, S.5
Rasmussen, B.6
Bosecke, P.7
Diat, O.8
Evans, P.R.9
-
52
-
-
0033566661
-
12-dependent enzyme provides new mechanistic insights
-
12-dependent enzyme provides new mechanistic insights. Structure 1999, 7, 891-902.
-
(1999)
Structure
, vol.7
, pp. 891-902
-
-
Reitzer, R.1
Gruber, K.2
Jogl, G.3
Wagner, U.G.4
Bothe, H.5
Buckel, W.6
Kratky, C.7
-
54
-
-
0032526407
-
Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism
-
Mancia, F.; Evans, P.R. Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism. Structure 1998, 6, 711-720.
-
(1998)
Structure
, vol.6
, pp. 711-720
-
-
Mancia, F.1
Evans, P.R.2
-
55
-
-
1242317113
-
Accurate redetermination of the X-ray structure and electronic bonding in adenosylcobalamin
-
Ouyang, L.Z.; Rulis, P.; Ching, W.Y.; Nardin, G.; Randaccio, L. Accurate redetermination of the X-ray structure and electronic bonding in adenosylcobalamin. Inorg. Chem. 2004, 43, 1235-1241.
-
(2004)
Inorg. Chem.
, vol.43
, pp. 1235-1241
-
-
Ouyang, L.Z.1
Rulis, P.2
Ching, W.Y.3
Nardin, G.4
Randaccio, L.5
-
57
-
-
33748619206
-
An NMR perspective on enzyme dynamics
-
Boehr, D.D.; Dyson, H.J.; Wright, P.E. An NMR perspective on enzyme dynamics. Chem. Rev. 2006, 106, 3055-3079.
-
(2006)
Chem. Rev.
, vol.106
, pp. 3055-3079
-
-
Boehr, D.D.1
Dyson, H.J.2
Wright, P.E.3
-
58
-
-
36849039429
-
A hierarchy of timescales in protein dynamics is linked to enzyme catalysis
-
Henzler-Wildman, K.A.; Lei, M.; Thai, V.; Kerns, S.J.; Karplus, M.; Kern, D. A hierarchy of timescales in protein dynamics is linked to enzyme catalysis. Nature 2007, 450, 913-916.
-
(2007)
Nature
, vol.450
, pp. 913-916
-
-
Henzler-Wildman, K.A.1
Lei, M.2
Thai, V.3
Kerns, S.J.4
Karplus, M.5
Kern, D.6
-
59
-
-
0346220393
-
The role of dynamics in allosteric regulation
-
Kern, D.; Zuiderweg, E.R. The role of dynamics in allosteric regulation. Curr. Opin. Struct. Biol. 2003, 13, 748-757.
-
(2003)
Curr. Opin. Struct. Biol.
, vol.13
, pp. 748-757
-
-
Kern, D.1
Zuiderweg, E.R.2
-
60
-
-
79953100071
-
Simulations of allosteric transitions
-
Elber, R. Simulations of allosteric transitions. Curr. Opin. Struct. Biol. 2011, 21, 167-172.
-
(2011)
Curr. Opin. Struct. Biol.
, vol.21
, pp. 167-172
-
-
Elber, R.1
-
61
-
-
0037022683
-
Network of coupled promoting motions in enzyme catalysis
-
Agarwal, P.K.; Billeter, S.R.; Rajagopalan, P.T.; Benkovic, S.J.; Hammes-Schiffer, S. Network of coupled promoting motions in enzyme catalysis. Proc. Natl. Acad. Sci. USA 2002, 99, 2794-2799.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2794-2799
-
-
Agarwal, P.K.1
Billeter, S.R.2
Rajagopalan, P.T.3
Benkovic, S.J.4
Hammes-Schiffer, S.5
-
62
-
-
1642399596
-
Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase
-
Evans, J.C.; Huddler, D.P.; Hilgers, M.T.; Romanchuk, G.; Matthews, R.G.; Ludwig, M.L. Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase. Proc. Natl. Acad. Sci. USA 2004, 101, 3729-3736.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3729-3736
-
-
Evans, J.C.1
Huddler, D.P.2
Hilgers, M.T.3
Romanchuk, G.4
Matthews, R.G.5
Ludwig, M.L.6
-
63
-
-
0038154035
-
Factors modulating conformational equilibria in large modular proteins: A case study with cobalamin-dependent methionine synthase
-
Bandarian, V.; Ludwig, M.L.; Matthews, R.G. Factors modulating conformational equilibria in large modular proteins: A case study with cobalamin-dependent methionine synthase. Proc. Natl. Acad. Sci. USA 2003, 100, 8156-8163.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8156-8163
-
-
Bandarian, V.1
Ludwig, M.L.2
Matthews, R.G.3
-
64
-
-
84863012809
-
12-dependent enzyme ornithine 4,5-aminomutase: A computational study
-
12-dependent enzyme ornithine 4,5-aminomutase: A computational study. J. Am. Chem. Soc. 2012, 134, 2367-2377.
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 2367-2377
-
-
Pang, J.Y.1
Li, X.2
Morokuma, K.3
Scrutton, N.S.4
Sutcliffe, M.J.5
-
65
-
-
0026444094
-
Structure of a substrate radical intermediate in the reaction of lysine 2,3-aminomutase
-
Ballinger, M.D.; Frey, P.A.; Reed, G.H. Structure of a substrate radical intermediate in the reaction of lysine 2,3-aminomutase. Biochemistry 1992, 31, 10782-10789.
-
(1992)
Biochemistry
, vol.31
, pp. 10782-10789
-
-
Ballinger, M.D.1
Frey, P.A.2
Reed, G.H.3
-
66
-
-
0029092235
-
Pulsed electron paramagnetic resonance studies of the lysine 2,3-aminomutase substrate radical: Evidence for participation of pyridoxal 5'-phosphate in a radical rearrangement
-
Ballinger, M.D.; Frey, P.A.; Reed, G.H.; LoBrutto, R. Pulsed electron paramagnetic resonance studies of the lysine 2,3-aminomutase substrate radical: Evidence for participation of pyridoxal 5'-phosphate in a radical rearrangement. Biochemistry 1995, 34, 10086-10093.
-
(1995)
Biochemistry
, vol.34
, pp. 10086-10093
-
-
Ballinger, M.D.1
Frey, P.A.2
Reed, G.H.3
LoBrutto, R.4
-
67
-
-
0029089648
-
Observation of a second substrate radical intermediate in the reaction of lysine 2,3-aminomutase: A radical centered on the β-carbon of the alternative substrate, 4-thia-L-lysine
-
Wu, W.; Lieder, K.W.; Reed, G.H.; Frey, P.A. Observation of a second substrate radical intermediate in the reaction of lysine 2,3-aminomutase: A radical centered on the β-carbon of the alternative substrate, 4-thia-L-lysine. Biochemistry 1995, 34, 10532-10537.
-
(1995)
Biochemistry
, vol.34
, pp. 10532-10537
-
-
Wu, W.1
Lieder, K.W.2
Reed, G.H.3
Frey, P.A.4
-
68
-
-
0025644318
-
Chemical model for the pyridoxal 5'-phosphate dependent lysine aminomutases
-
Han, O.; Frey, P.A. Chemical model for the pyridoxal 5'-phosphate dependent lysine aminomutases. J. Am. Chem. Soc. 1990, 112, 8982-8983.
-
(1990)
J. Am. Chem. Soc.
, vol.112
, pp. 8982-8983
-
-
Han, O.1
Frey, P.A.2
-
69
-
-
84872512713
-
Mechanism-based inhibition reveals transitions between two conformational states in the action of lysine 5,6-aminomutase: A combination of electron paramagnetic resonance spectroscopy, electron nuclear double resonance spectroscopy, and density functional theory study
-
Chen, Y.H.; Maity, A.N.; Frey, P.A.; Ke, S.C. Mechanism-based inhibition reveals transitions between two conformational states in the action of lysine 5,6-aminomutase: A combination of electron paramagnetic resonance spectroscopy, electron nuclear double resonance spectroscopy, and density functional theory study. J. Am. Chem. Soc. 2013, 135, 788-794.
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 788-794
-
-
Chen, Y.H.1
Maity, A.N.2
Frey, P.A.3
Ke, S.C.4
-
70
-
-
58049197851
-
Mechanism of radical-based catalysis in the reaction catalyzed by adenosylcobalamin-dependent ornithine 4,5-aminomutase
-
Wolthers, K.R.; Rigby, S.E.J.; Scrutton, N.S. Mechanism of radical-based catalysis in the reaction catalyzed by adenosylcobalamin-dependent ornithine 4,5-aminomutase. J. Biol. Chem. 2008, 283, 34615-34625.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 34615-34625
-
-
Wolthers, K.R.1
Rigby, S.E.J.2
Scrutton, N.S.3
-
71
-
-
0034622621
-
Protection of radical intermediates at the active site of adenosylcobalamin-dependent methylmalonyl-CoA mutase
-
Thoma, N.H.; Evans, P.R.; Leadlay, P.F. Protection of radical intermediates at the active site of adenosylcobalamin-dependent methylmalonyl-CoA mutase. Biochemistry 2000, 39, 9213-9221.
-
(2000)
Biochemistry
, vol.39
, pp. 9213-9221
-
-
Thoma, N.H.1
Evans, P.R.2
Leadlay, P.F.3
-
72
-
-
0033525074
-
12-dependent diol dehydratase
-
12-dependent diol dehydratase. J. Biol. Chem. 1999, 274, 3372-3377.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 3372-3377
-
-
Toraya, T.1
Mori, K.2
-
73
-
-
84855864074
-
Role of histidine 225 in adenosylcobalamin-dependent ornithine 4,5-aminomutase
-
Makins, C.; Miros, F.N.; Scrutton, N.S.; Wolthers, K.R. Role of histidine 225 in adenosylcobalamin-dependent ornithine 4,5-aminomutase. Bioorg. Chem. 2012, 40, 39-47.
-
(2012)
Bioorg. Chem.
, vol.40
, pp. 39-47
-
-
Makins, C.1
Miros, F.N.2
Scrutton, N.S.3
Wolthers, K.R.4
-
74
-
-
84870625730
-
12
-
12. Chem. Eur. J. 2012, 18, 16114-16122.
-
(2012)
Chem. Eur. J.
, vol.18
, pp. 16114-16122
-
-
Friedrich, P.1
Baisch, U.2
Harrington, R.W.3
Lyatuu, F.4
Zhou, K.5
Zelder, F.6
McFarlane, W.7
Buckel, W.8
Golding, B.T.9
-
76
-
-
33845974304
-
ESR of fine radicals in enzymatic systems
-
In Berliner, L.J., Reuben, J., Eds.; Plenum: New York, NY, USA
-
Edmondson, D.E. ESR of fine radicals in enzymatic systems. In Biological Magnetic Resonance; Berliner, L.J., Reuben, J., Eds.; Plenum: New York, NY, USA, 1978; Volume 1, pp. 205-237.
-
(1978)
Biological Magnetic Resonance
, vol.1
, pp. 205-237
-
-
Edmondson, D.E.1
-
77
-
-
0000907326
-
Electron nuclear double resonance (ENDOR) of metalloenzymes
-
Hoffman, B.M. Electron nuclear double resonance (ENDOR) of metalloenzymes. Acc. Chem. Res. 1991, 24, 164-170.
-
(1991)
Acc. Chem. Res.
, vol.24
, pp. 164-170
-
-
Hoffman, B.M.1
-
78
-
-
0038506974
-
ENDOR of metalloenzymes
-
Hoffman, B.M. ENDOR of metalloenzymes. Acc. Chem. Res. 2003, 36, 522-529.
-
(2003)
Acc. Chem. Res.
, vol.36
, pp. 522-529
-
-
Hoffman, B.M.1
-
79
-
-
33746918356
-
How an enzyme tames reactive intermediates: Positioning of the active-site components of lysine 2,3-aminomutase during enzymatic turnover as determined by ENDOR spectroscopy
-
Lees, N.S.; Chen, D.; Walsby, C.J.; Behshad, E.; Frey, P.A.; Hoffman, B.M. How an enzyme tames reactive intermediates: Positioning of the active-site components of lysine 2,3-aminomutase during enzymatic turnover as determined by ENDOR spectroscopy. J. Am. Chem. Soc. 2006, 128, 10145-10154.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 10145-10154
-
-
Lees, N.S.1
Chen, D.2
Walsby, C.J.3
Behshad, E.4
Frey, P.A.5
Hoffman, B.M.6
-
80
-
-
0002607879
-
12-dependent enzymes
-
In Banerjee, R., Ed.; Wiley-Interscience: New York, NY, USA
-
12; Banerjee, R., Ed.; Wiley-Interscience: New York, NY, USA, 1999; pp. 165-195.
-
(1999)
12
, pp. 165-195
-
-
Gerfen, G.J.1
-
81
-
-
0008071254
-
-
12; Dolphin, D., Ed.; John Wiley & Sons: New York, NY, USA
-
12; Dolphin, D., Ed.; John Wiley & Sons: New York, NY, USA, 1982; Volume 1, pp. 431-462.
-
(1982)
12-dependent enzyme reaction and related systems
, vol.1
, pp. 431-462
-
-
Pilbrow, J.R.1
-
82
-
-
0346850974
-
The positions of radical intermediates in the active sites of adenosylcobalamin-dependent enzymes
-
Reed, G.H.; Mansoorabadi, S.O. The positions of radical intermediates in the active sites of adenosylcobalamin-dependent enzymes. Curr. Opin. Struct. Biol. 2003, 13, 716-721.
-
(2003)
Curr. Opin. Struct. Biol.
, vol.13
, pp. 716-721
-
-
Reed, G.H.1
Mansoorabadi, S.O.2
-
83
-
-
33749022253
-
Reaction of adenosylcobalamin-dependent glutamate mutase with 2-thiolglutarate
-
Yoon, M.; Patwardhan, A.; Qiao, C.; Mansoorabadi, S.O.; Menefee, A.L.; Reed, G.H.; Marsh, E.N. Reaction of adenosylcobalamin-dependent glutamate mutase with 2-thiolglutarate. Biochemistry 2006, 45, 11650-11657.
-
(2006)
Biochemistry
, vol.45
, pp. 11650-11657
-
-
Yoon, M.1
Patwardhan, A.2
Qiao, C.3
Mansoorabadi, S.O.4
Menefee, A.L.5
Reed, G.H.6
Marsh, E.N.7
-
84
-
-
14644401110
-
Characterization of a succinyl-CoA radical-cob (II) alamin spin triplet intermediate in the reaction catalyzed by adenosylcobalamin-dependent methylmalonyl-CoA mutase
-
Mansoorabadi, S.O.; Padmakumar, R.; Fazliddinova, N.; Vlasie, M.; Banerjee, R.; Reed, G.H. Characterization of a succinyl-CoA radical-cob (II) alamin spin triplet intermediate in the reaction catalyzed by adenosylcobalamin-dependent methylmalonyl-CoA mutase. Biochemistry 2005, 44, 3153-3158.
-
(2005)
Biochemistry
, vol.44
, pp. 3153-3158
-
-
Mansoorabadi, S.O.1
Padmakumar, R.2
Fazliddinova, N.3
Vlasie, M.4
Banerjee, R.5
Reed, G.H.6
-
85
-
-
69249158333
-
Radical triplets and suicide inhibition in reactions of 4-thia-D-and 4-thia-L-lysine with lysine 5,6-aminomutase
-
Tang, K.H.; Mansoorabadi, S.O.; Reed, G.H.; Frey, P.A. Radical triplets and suicide inhibition in reactions of 4-thia-D-and 4-thia-L-lysine with lysine 5,6-aminomutase. Biochemistry 2009, 48, 8151-8160.
-
(2009)
Biochemistry
, vol.48
, pp. 8151-8160
-
-
Tang, K.H.1
Mansoorabadi, S.O.2
Reed, G.H.3
Frey, P.A.4
-
86
-
-
69949119684
-
Evidence for conformational movement and radical mechanism in the reaction of 4-thia-L-lysine with lysine 5,6-aminomutase
-
Maity, A.N.; Hsieh, C.P.; Huang, M.H.; Chen, Y.H.; Tang, K.H.; Behshad, E.; Frey, P.A.; Ke, S.C. Evidence for conformational movement and radical mechanism in the reaction of 4-thia-L-lysine with lysine 5,6-aminomutase. J. Phys. Chem. 2009, 113, 12161-12163.
-
(2009)
J. Phys. Chem.
, vol.113
, pp. 12161-12163
-
-
Maity, A.N.1
Hsieh, C.P.2
Huang, M.H.3
Chen, Y.H.4
Tang, K.H.5
Behshad, E.6
Frey, P.A.7
Ke, S.C.8
-
87
-
-
0037047017
-
12-dependent ethanolamine ammonia-lyase catalyzed reaction of (S)-2-aminopropanol
-
12-dependent ethanolamine ammonia-lyase catalyzed reaction of (S)-2-aminopropanol. Biochemistry 2002, 41, 8580-8588.
-
(2002)
Biochemistry
, vol.41
, pp. 8580-8588
-
-
Bandarian, V.1
Reed, G.H.2
-
88
-
-
0037451744
-
Spin-spin interaction in ethanolamine deaminase
-
Ke, S.C. Spin-spin interaction in ethanolamine deaminase. Biochim. Biophys. Acta 2003, 1620, 267-272.
-
(2003)
Biochim. Biophys. Acta
, vol.1620
, pp. 267-272
-
-
Ke, S.C.1
-
90
-
-
0034705081
-
Identification of cis-ethanesemidione as the organic radical derived from glycolaldehyde in the suicide inactivation of dioldehydrase and of ethanolamine ammonia-lyase
-
Abend, A.; Bandarian, V.; Reed, G.H.; Frey, P.A. Identification of cis-ethanesemidione as the organic radical derived from glycolaldehyde in the suicide inactivation of dioldehydrase and of ethanolamine ammonia-lyase. Biochemistry 2000, 39, 6250-6257.
-
(2000)
Biochemistry
, vol.39
, pp. 6250-6257
-
-
Abend, A.1
Bandarian, V.2
Reed, G.H.3
Frey, P.A.4
-
92
-
-
84860242365
-
13C]glycine: Access to site-directed isotopomers of 2-aminoethanol, 2-bromoethylamine and 4-thialysine
-
13C]glycine: Access to site-directed isotopomers of 2-aminoethanol, 2-bromoethylamine and 4-thialysine. Amino Acids 2012, 42, 309-315.
-
(2012)
Amino Acids
, vol.42
, pp. 309-315
-
-
Maity, A.N.1
Shaikh, A.C.2
Srimurugan, S.3
Wu, C.J.4
Chen, C.P.5
Ke, S.-C.6
-
93
-
-
80055010575
-
Radical stabilization is crucial in the mechanism of action of lysine 5,6-aminomutase: Role of tyrosine-263α as revealed by electron paramagnetic resonance spectroscopy
-
Chen, Y.H.; Maity, A.N.; Pan, Y.C.; Frey, P.A.; Ke, S.-C. Radical stabilization is crucial in the mechanism of action of lysine 5,6-aminomutase: role of tyrosine-263α as revealed by electron paramagnetic resonance spectroscopy. J. Am. Chem. Soc. 2011, 133, 17152-17155.
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 17152-17155
-
-
Chen, Y.H.1
Maity, A.N.2
Pan, Y.C.3
Frey, P.A.4
Ke, S.-C.5
-
96
-
-
33845587345
-
In search of radical intermediates in the reactions catalyzed by lysine 2,3-aminomutase and lysine 5,6-aminomutase
-
Sandala, G.M.; Smith, D.M.; Radom, L. In search of radical intermediates in the reactions catalyzed by lysine 2,3-aminomutase and lysine 5,6-aminomutase. J. Am. Chem. Soc. 2006, 128, 16004-16005.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 16004-16005
-
-
Sandala, G.M.1
Smith, D.M.2
Radom, L.3
-
97
-
-
0034622523
-
Lysine 2,3-aminomutase and trans-4,5-dehydrolysine: Characterization of an allylic analogue of a substrate-based radical in the catalytic mechanism
-
Wu, W.; Booker, S.; Lieder, K.W.; Bandarian, V.; Reed, G.H.; Frey, P.A. Lysine 2,3-aminomutase and trans-4,5-dehydrolysine: Characterization of an allylic analogue of a substrate-based radical in the catalytic mechanism. Biochemistry 2000, 39, 9561-9570.
-
(2000)
Biochemistry
, vol.39
, pp. 9561-9570
-
-
Wu, W.1
Booker, S.2
Lieder, K.W.3
Bandarian, V.4
Reed, G.H.5
Frey, P.A.6
-
98
-
-
0001136531
-
Nitrogen-centered free radicals. VII. Electron spin resonance investigation of the 1-aziridylcarbinyl and related free radicals
-
Danen, W.C.; West, C.T. Nitrogen-centered free radicals. VII. Electron spin resonance investigation of the 1-aziridylcarbinyl and related free radicals. J. Am. Chem. Soc. 1974, 96, 2447-2453.
-
(1974)
J. Am. Chem. Soc.
, vol.96
, pp. 2447-2453
-
-
Danen, W.C.1
West, C.T.2
-
99
-
-
84883643609
-
5-Fluorolysine as alternative substrate of lysine 5,6-aminomutase: A computational study
-
Maity, A.N.; Ke, S.-C. 5-Fluorolysine as alternative substrate of lysine 5,6-aminomutase: A computational study. Comput. Theor. Chem. 2013, 1022, 1-5.
-
(2013)
Comput. Theor. Chem.
, vol.1022
, pp. 1-5
-
-
Maity, A.N.1
Ke, S.-C.2
-
101
-
-
79959778389
-
Crystal structures of aspartate aminotransferase reconstituted with 1-deazapyridoxal 5'-phosphate: Internal aldimine and stable L-aspartate external aldimine
-
Griswold, W.R.; Fisher, A.J.; Toney, M.D. Crystal structures of aspartate aminotransferase reconstituted with 1-deazapyridoxal 5'-phosphate: Internal aldimine and stable L-aspartate external aldimine. Biochemistry 2011, 50, 5918-5924.
-
(2011)
Biochemistry
, vol.50
, pp. 5918-5924
-
-
Griswold, W.R.1
Fisher, A.J.2
Toney, M.D.3
-
102
-
-
80052819676
-
Role of the pyridine nitrogen in pyridoxal 5'-phosphate catalysis: Activity of three classes of PLP enzymes reconstituted with deazapyridoxal 5'-phosphate
-
Griswold, W.R.; Toney, M.D. Role of the pyridine nitrogen in pyridoxal 5'-phosphate catalysis: Activity of three classes of PLP enzymes reconstituted with deazapyridoxal 5'-phosphate. J. Am. Chem. Soc. 2011, 133, 14823-14830.
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 14823-14830
-
-
Griswold, W.R.1
Toney, M.D.2
-
103
-
-
84861371017
-
Ground-state electronic destabilization via hyperconjugation in aspartate aminotransferase
-
Griswold, W.R.; Castro, J.N.; Fisher, A.J.; Toney, M.D. Ground-state electronic destabilization via hyperconjugation in aspartate aminotransferase. J. Am. Chem. Soc. 2012, 134, 8436-8438.
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 8436-8438
-
-
Griswold, W.R.1
Castro, J.N.2
Fisher, A.J.3
Toney, M.D.4
-
104
-
-
75449092895
-
Chemoenzymatic synthesis of 1-deaza-pyridoxal 5'-phosphate
-
Griswold, W.R.; Toney, M.D. Chemoenzymatic synthesis of 1-deaza-pyridoxal 5'-phosphate. Bioorg. Med. Chem. Lett. 2010, 20, 1352-1354.
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, pp. 1352-1354
-
-
Griswold, W.R.1
Toney, M.D.2
-
105
-
-
84882268663
-
Reconstitution of the pyridoxal 5'-phosphate (PLP) dependent enzyme serine palmitoyltransferase (SPT) with pyridoxal reveals a crucial role for the phosphate during catalysis
-
Beattie, A.E.; Clarke, D.J.; Wadsworth, J.M.; Lowther, J.; Sin, H.L.; Campopiano, D.J. Reconstitution of the pyridoxal 5'-phosphate (PLP) dependent enzyme serine palmitoyltransferase (SPT) with pyridoxal reveals a crucial role for the phosphate during catalysis. Chem. Commun. 2013, 49, 7058-7060.
-
(2013)
Chem. Commun.
, vol.49
, pp. 7058-7060
-
-
Beattie, A.E.1
Clarke, D.J.2
Wadsworth, J.M.3
Lowther, J.4
Sin, H.L.5
Campopiano, D.J.6
-
106
-
-
79959308926
-
Aminomutases: Mechanistic diversity, biotechnological applications and future perspectives
-
Wu, B.; Szymanski, W.; Heberling, M.M.; Feringa, B.L.; Janssen, D.B. Aminomutases: Mechanistic diversity, biotechnological applications and future perspectives. Trends Biotech. 2011, 29, 352-362.
-
(2011)
Trends Biotech.
, vol.29
, pp. 352-362
-
-
Wu, B.1
Szymanski, W.2
Heberling, M.M.3
Feringa, B.L.4
Janssen, D.B.5
-
107
-
-
34247608118
-
Effect of the diamine nonleaving group in platinum-acridinylthiourea conjugates on DNA damage and cytotoxicity
-
Guddneppanavar, R.; Choudhury, J.R.; Kheradi, A.R.; Steen, B.D.; Saluta, G.; Kucera, G.L.; Day, C.S.; Bierbach, U. Effect of the diamine nonleaving group in platinum-acridinylthiourea conjugates on DNA damage and cytotoxicity. J. Med. Chem. 2007, 50, 2259-2263.
-
(2007)
J. Med. Chem.
, vol.50
, pp. 2259-2263
-
-
Guddneppanavar, R.1
Choudhury, J.R.2
Kheradi, A.R.3
Steen, B.D.4
Saluta, G.5
Kucera, G.L.6
Day, C.S.7
Bierbach, U.8
-
108
-
-
33745836681
-
Polyamine analogues down-regulate estrogen receptor α expression in human breast cancer cells
-
Huang, Y.; Keen, J.C.; Pledgie, A.; Marton, L.J.; Zhu, T.; Sukumar, S.; Park, B.H.; Blair, B.; Brenner, K.; Casero, R.A.; et al. Polyamine analogues down-regulate estrogen receptor α expression in human breast cancer cells. J. Biol. Chem. 2006, 281, 19055-19063.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 19055-19063
-
-
Huang, Y.1
Keen, J.C.2
Pledgie, A.3
Marton, L.J.4
Zhu, T.5
Sukumar, S.6
Park, B.H.7
Blair, B.8
Brenner, K.9
Casero, R.A.10
-
109
-
-
0242665622
-
Die absolute konfiguration der 3,5-diaminohexansäure aus der β-lysin-mutase-reaktion
-
Kunz, F.; Rétey, J.; Arigoni, D.; Tsai, L.; Stadtman, T.C. Die absolute konfiguration der 3,5-diaminohexansäure aus der β-lysin-mutase-reaktion. Helv. Chim. Acta 1978, 61, 1139-1145.
-
(1978)
Helv. Chim. Acta
, vol.61
, pp. 1139-1145
-
-
Kunz, F.1
Rétey, J.2
Arigoni, D.3
Tsai, L.4
Stadtman, T.C.5
-
110
-
-
33750286042
-
Enantiomeric free radicals and enzymatic control of stereochemistry in a radical mechanism: The case of lysine 2,3-aminomutases
-
Behshad, E.; Ruzicka, F.J.; Mansoorabadi, S.O.; Chen, D.; Reed, G.H.; Frey, P.A. Enantiomeric free radicals and enzymatic control of stereochemistry in a radical mechanism: The case of lysine 2,3-aminomutases. Biochemistry 2006, 45, 12639-12646.
-
(2006)
Biochemistry
, vol.45
, pp. 12639-12646
-
-
Behshad, E.1
Ruzicka, F.J.2
Mansoorabadi, S.O.3
Chen, D.4
Reed, G.H.5
Frey, P.A.6
-
111
-
-
10744223235
-
5-Fluorinated L-lysine analogues as selective induced nitric oxide synthase inhibitors
-
Hallinan, E.A.; Hagen, T.J.; Bergmanis, A.; Moore, W.M.; Jerome, G.M.; Spangler, D.P.; Stevens, A.M.; Shieh, H.S.; Manning, P.T.; Pitzele, B.S. 5-Fluorinated L-lysine analogues as selective induced nitric oxide synthase inhibitors. J. Med. Chem. 2004, 47, 900-906.
-
(2004)
J. Med. Chem.
, vol.47
, pp. 900-906
-
-
Hallinan, E.A.1
Hagen, T.J.2
Bergmanis, A.3
Moore, W.M.4
Jerome, G.M.5
Spangler, D.P.6
Stevens, A.M.7
Shieh, H.S.8
Manning, P.T.9
Pitzele, B.S.10
-
112
-
-
78650109936
-
Kinetic and spectroscopic evidence of negative cooperativity in the action of lysine 2,3-aminomutase
-
Ruzicka, F.J.; Frey, P.A. Kinetic and spectroscopic evidence of negative cooperativity in the action of lysine 2,3-aminomutase. J. Phys. Chem. 2010, 114, 16118-16124.
-
(2010)
J. Phys. Chem.
, vol.114
, pp. 16118-16124
-
-
Ruzicka, F.J.1
Frey, P.A.2
|