Radical use of rossmann and TIM barrel architectures for controlling coenzyme B12 chemistry

Annual Review of Biophysics

Volumn 41, Issue 1, 2012, Pages 403-427

  Dowling, Daniel P ^a   Croft, Anna K ^c   Drennan, Catherine L ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c BANGOR UNIVERSITY   (United Kingdom)

Author keywords

Aminomutases; Carbon skeleton mutases; Protein folds; Radical enzymes; X ray crystallography

Indexed keywords

COBALAMIN; COBAMAMIDE; HYDROGEN; LYSINE 5,6 AMINOMUTASE; METHYLASPARTATE MUTASE; METHYLMALONYL COENZYME A MUTASE; MUTASE; ORNITHINE 4,5 AMINOMUTASE; UNCLASSIFIED DRUG;

ATOM; BACTERIUM; CATALYSIS; CATALYST; CHEMICAL BOND; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; FERMENTATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; REVIEW;

BACTERIA; CATALYSIS; CATALYTIC DOMAIN; COBAMIDES; FREE RADICALS; HUMANS; INTRAMOLECULAR TRANSFERASES; IRON; LIGANDS; METHYLMALONYL-COA MUTASE; S-ADENOSYLMETHIONINE; VITAMIN B 12;

HARNESS;

EID: 84861405071     PISSN: 1936122X     EISSN: 19361238     Source Type: Book Series    
DOI: 10.1146/annurev-biophys-050511-102225     Document Type: Review

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