Mechanism of radical-based catalysis in the reaction catalyzed by adenosylcobalamin-dependent ornithine 4,5-aminomutase

Journal of Biological Chemistry

Volumn 283, Issue 50, 2008, Pages 34615-34625

  Wolthers, Kirsten R ^a   Rigby, Stephen E J ^a   Scrutton, Nigel S ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; AMINES; CATALYSIS; COBALT; ELECTRON SPIN RESONANCE SPECTROSCOPY; ISOMERS; NITROGEN COMPOUNDS; SUBSTRATES;

ABSORBANCE; ADENOSYLCOBALAMIN; ALDIMINE; ELECTRONIC COUPLINGS; EQUILIBRIUM DISTRIBUTIONS; EXTERNAL-; HOMOLYSIS; INTERMEDIATE STATES; KINETIC PHASES; LONG TIMES; REACTION CATALYZED; REACTION MECHANISMS; SUBSTRATE ANALOGUES; TAUTOMERIC FORMS; TERMINAL AMINO GROUPS;

ENZYMES;

2,4 DIAMINOBUTYRIC ACID; COBAMAMIDE; ORNITHINE 4,5 AMINOMUTASE; ORNITHINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ENZYME BINDING; ENZYME PURIFICATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REACTION ANALYSIS;

AMINOBUTYRIC ACIDS; CATALYSIS; CLOSTRIDIUM STICKLANDII; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; IMINES; INTRAMOLECULAR TRANSFERASES; KINETICS; LIGANDS; MODELS, CHEMICAL; ORNITHINE; PROTEIN CONFORMATION; SPECTROPHOTOMETRY; SPECTROPHOTOMETRY, ULTRAVIOLET; SUBSTRATE SPECIFICITY;

EID: 58049197851     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807911200     Document Type: Article

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