Factors modulating conformational equilibria in large modular proteins: A case study with cobalamin-dependent methionine synthase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 14, 2003, Pages 8156-8163

  Bandarian, Vahe ^a   Ludwig, Martha L ^a,b   Matthews, Rowena G ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; COBALAMIN; HOMOCYSTEINE; LIGAND; METHIONINE; METHIONINE SYNTHASE; PROTEIN; S ADENOSYLMETHIONINE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CHEMICAL REACTION; CHROMATOPHORE; ENZYME ACTIVATION; EQUILIBRIUM CONSTANT; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION; STEREOSPECIFICITY;

5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE S-METHYLTRANSFERASE; AMINO ACID SUBSTITUTION; CATALYSIS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HOMOCYSTEINE; METHIONINE; METHYLATION; MUTATION, MISSENSE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; S-ADENOSYLMETHIONINE; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TEMPERATURE; TETRAHYDROFOLATES; VITAMIN B 12;

EID: 0038154035     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1133218100     Document Type: Article

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