Crystal structures of aspartate aminotransferase reconstituted with 1-deazapyridoxal 5′-phosphate: Internal aldimine and stable l -aspartate external aldimine

Biochemistry

Volumn 50, Issue 26, 2011, Pages 5918-5924

  Griswold, Wait R ^a   Fisher, Andrew J ^a   Toney, Michael D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ALDIMINES; AMINO GROUP; ASPARTATE AMINOTRANSFERASE; ASPARTATES; CATALYTIC BASE; COCRYSTALLIZATION; MECHANISTIC DIFFERENCES; METHYL GROUP; PLANARITY; PYRIDINE RINGS; SCHIFF-BASE; STERIC BULK;

ESCHERICHIA COLI; FUNCTIONAL GROUPS; HYDROGEN BONDS;

HYDROGEN;

1 DEAZAPYRIDOXAL 5' PHOSPHATE; ALDIMINE; ALPHA METHYL ASPARTATE; AMINO ACID; ASPARTATE AMINOTRANSFERASE; ASPARTIC ACID; BACTERIAL ENZYME; ESCHERICHIA COLI ASPARTATE AMINOTRANSFERASE; METHYL GROUP; PYRIDINE; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; CATALYSIS; CRYSTAL STRUCTURE; ENZYME STRUCTURE; HYDROGEN BOND; PRIORITY JOURNAL;

ASPARTATE AMINOTRANSFERASES; ASPARTIC ACID; BENZALDEHYDES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME STABILITY; ESCHERICHIA COLI; IMINES; MODELS, MOLECULAR; PHOSPHORIC ACID ESTERS;

ESCHERICHIA COLI;

EID: 79959778389     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200436y     Document Type: Article

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