Polyamine analogues down-regulate estrogen receptor α expression in human breast cancer cells

Journal of Biological Chemistry

Volumn 281, Issue 28, 2006, Pages 19055-19063

  Huang, Yi ^a   Keen, Judith C ^a   Pledgie, Allison ^a   Marton, Laurence J ^b   Zhu, Tao ^a   Sukumar, Saraswati ^a   Park, Ben Ho ^a   Blair, Brian ^a   Brenner, Keith ^a   Casero Jr , Robert A ^a   Davidson, Nancy E ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b Cellgate Incorporated   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BIOPOLYMERS; ENZYME INHIBITION; HORMONES; RNA; TUMORS;

BREAST CANCER; OLIGOAMINES; POLYAMINES; STEROID HORMONAL RECEPTORS;

CELLS;

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MESSENGER RNA; POLYAMINE DERIVATIVE; PROTEIN C JUN; STEROID RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TRANSCRIPTION FACTOR SP1;

ARTICLE; BINDING SITE; BIOLOGICAL ACTIVITY; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DNA BINDING; DOWN REGULATION; DRUG INHIBITION; ENZYME ACTIVATION; GC RICH SEQUENCE; GENE REPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

BREAST NEOPLASMS; CELL LINE, TUMOR; CYTOMEGALOVIRUS; DOWN-REGULATION; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR MODULATORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; POLYAMINES; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR;

CYTOMEGALOVIRUS;

EID: 33745836681     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M600910200     Document Type: Article

References (26)

1. Huang, Y., Pledgie, A. M., Casero, R. A., and Davidson, N. E. (2005) Anticancer Drugs 16, 229-241
2. Russell, D. H. (1983) Crit. Rev. Clin. Lab. Sci. 18, 261-311
3. LaMuraglia, G. M., Lacaine, F., and Malt, R. A. (1986) Ann. Surg. 204, 89-93
4. Porter, C. W., Herrera-Ornelas, L., Pera, P., Petrelli, N. F., and Mittelman, A. (1987) Cancer 60, 1275-1281
5. Manni, A. (2002) In Vivo 16, 493-500
6. Manni, A. (1994) Cancer Treat. Res. 71, 209-225
7. Leveque, J., Foucher, F., Bansard, J. Y., Havouis, R., Grall, J. Y., and Moulinoux, J. P. (2000) Breast Cancer Res. Treat. 60, 99-105
8. Marton, L. J., and Pegg, A. E. (1995) Annu. Rev. Pharmacol. Toxicol. 35, 55-91
9. Valasinas, A., Reddy, V. K., Blokhin, A. V., Basu, H. S., Bhattacharya, S., Sarkar, A., Marton, L. J., and Frydman, B. (2003) Bioorg. Med. Chem. 11, 4121-4131
10. Huang, Y., Hager, E. R., Phillips, D. L., Dunn, V. R., Hacker, A., Frydman, B., Kink, J. A., Valasinas, A. L., Reddy, V. K., Marton, L. J., Casero, R. A., and Davidson, N. E. (2003) Clin. Cancer Res. 9, 2769-2777
11. Huang, Y., Keen, J. C., Hager, E., Smith, R., Hacker, A., Frydman, B., Valasinas, A. L., Reddy, V. K., Marton, L. J., Casero, R. A., Jr., and Davidson, N. E. (2004) Mol. Cancer Res. 2, 81-88
12. Thomas, T., and Thomas, T. J. (1993) Breast Cancer Res. Treat. 29, 189-201
13. Cohen, F. J., Manni, A., Glikman, P., Bartholomew, M., and Demers, L. (1988) Cancer Res. 48, 6819-6825
14. Shah, N., Thomas, T. J., Lewis, J. S., Klinge, C. M., Shirahata, A., Gelinas, C., and Thomas, T. (2001) Oncogene 20, 1715-1729
15. Bacchi, C. J., Weiss, L. M., Lane, S., Frydman, B., Valasinas, A., Reddy, V., Sun, J. S., Marton, L. J, Khan, I. A., Moretto, M., Yarlett, N., and Wittner, M. (2002) Antimicrob. Agents Chemother. 46, 55-61
16. Keen, J. C., Zhou, Q., Park, B. H., Pettit, C., Mack, K. M., Blair, B., Brenner, K., and Davidson, N. E. (2005) J. Biol. Chem. 280, 29519-29524
17. deGraffenried, L. A., Hilsenbeck, S. G., and Fuqua, S. A. (2002) J. Steroid Biochem. Mol. Biol. 82, 7-18
18. Sharma, D., Blum, J., Yang, X., Beaulieu, N., Macleod, A. R., and Davidson, N. E. (2005) Mol. Endocrinol. 19, 1740-1751
19. Huang, Y., Pledgie, A., Rubin, E., Marton, L. J., Woster, P. M., Sukumar, S., Casero, R. A., and Davidson, N. E. (2005) Cancer Biol. Ther. 4, 1006-1013
20. deConinck, E. C., McPherson, L. A., and Weigel, R. J. (1995) Mol. Cell. Biol. 15, 2191-2196
21. Tang, Z., Treilleux, I., and Brown, M. (1997) Mol. Cell. Biol. 17, 1274-1280
22. Haworth, I. S., Rodger, A., and Richards, W. G. (1991) Proc. Biol. Sci. 244, 107-116
23. Zakrzewska, K., and Pullman, B. (1986) Biopolymers 25, 375-392
24. Feuerstein, B. G., Williams, L. D., Basu, H. S., and Marton, L. J. (1991) J. Cell. Biochem. 46, 37-47
25. Panagiotidis, C. A., Artandi, S., Calame, K., and Silverstein, S. J. (1995) Nucleic Acids Res. 23, 1800-1809
26. Tomitori, H., Nenoi, M., Mita, K., Daino, K., Igarashi, K., and Ichimura, S. (2002) Biochim. Biophys. Acta 1579, 180-184