Radical stabilization is crucial in the mechanism of action of lysine 5,6-aminomutase: Role of tyrosine-263α as revealed by electron paramagnetic resonance spectroscopy

Journal of the American Chemical Society

Volumn 133, Issue 43, 2011, Pages 17152-17155

  Chen, Yung Han ^a   Maity, Amarendra N ^a   Pan, Yu Chiang ^a   Frey, Perry A ^b   Ke, Shyue Chu ^a  

^a NATIONAL DONG HWA UNIVERSITY   (Taiwan)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ADENOSYLCOBALAMIN; ELECTRON PARAMAGNETIC RESONANCE SPECTROSCOPY; ENZYMATIC ACTIVITIES; HIGH ENERGY; MECHANISM OF ACTION; PYRIDINE RINGS; REACTION MECHANISM; SPIN TRANSFER; STACKING INTERACTION;

AMINO ACIDS; FREE RADICALS; ISOTOPES; MOLECULAR OXYGEN; PARAMAGNETIC RESONANCE; PARAMAGNETISM; SPECTROSCOPY;

ELECTRON SPIN RESONANCE SPECTROSCOPY;

COBAMAMIDE; ISOMERASE; LYSINE 5,6 AMINOMUTASE; OXYGEN; PYRIDOXAL 5 PHOSPHATE; TYROSINE; UNCLASSIFIED DRUG;

ANAEROBIC BACTERIUM; ARTICLE; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ENZYME STABILITY; ENZYME STRUCTURE; MOLECULAR INTERACTION; MOLECULAR MECHANICS;

CRYSTALLOGRAPHY, X-RAY; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; INTRAMOLECULAR TRANSFERASES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STEREOISOMERISM; TYROSINE;

EID: 80055010575     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja207766c     Document Type: Article

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