Germline stem cell arrest inhibits the collapse of somatic proteostasis early in Caenorhabditis elegans adulthood

Aging Cell

Volumn 12, Issue 5, 2013, Pages 814-822

  Shemesh, Netta ^a   Shai, Nadav ^a   Ben Zvi, Anat ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Aging; daf 16; Germline stem cells; hsf 1; Proteostasis; Reproduction

Indexed keywords

ADULT ANIMAL; ADULTHOOD; ARTICLE; BIOMASS PRODUCTION; CAENORHABDITIS ELEGANS; CELL CYCLE ARREST; CELLULAR STRESS RESPONSE; COLONY COLLAPSE; CONTROLLED STUDY; GERMLINE STEM CELL; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN HOMEOSTASIS; PROTEIN QUALITY; QUALITY CONTROL; RNA INTERFERENCE; SOMATIC CELL; UNFOLDED PROTEIN RESPONSE;

ANIMALIA; CAENORHABDITIS ELEGANS;

AGING; DAF-16; GERMLINE STEM CELLS; HSF-1; PROTEOSTASIS; REPRODUCTION;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; FEMALE; GERM CELLS; LONGEVITY; MALE; PROTEIN FOLDING; PROTEOSTASIS DEFICIENCIES; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 84883767608     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12110     Document Type: Article

References (33)

1. Akerfelt M, Morimoto RI, Sistonen L (2010) Heat shock factors: integrators of cell stress, development and lifespan. Nat. Rev. Mol. Cell Biol. 11, 545-555.
2. Alper S, McElwee MK, Apfeld J, Lackford B, Freedman JH, Schwartz DA (2010) The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity. J. Biol. Chem. 285, 1822-1828.
3. Antebi A (2012) Regulation of longevity by the reproductive system. Exp. Gerontol. doi: 10.1016/j.exger.2012.09.009 (in press).
4. Arantes-Oliveira N, Apfeld J, Dillin A, Kenyon C (2002) Regulation of life-span by germ-line stem cells in Caenorhabditis elegans. Science 295, 502-505.
5. Arias E, Cuervo AM (2011) Chaperone-mediated autophagy in protein quality control. Curr. Opin. Cell Biol. 23, 184-189.
6. Ben-Zvi A, Miller EA, Morimoto RI (2009) Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging. Proc. Natl Acad. Sci. USA 106, 14914-14919.
7. Berman JR, Kenyon C (2006) Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling. Cell 124, 1055-1068.
8. Cohen E, Du D, Joyce D, Kapernick EA, Volovik Y, Kelly JW, Dillin A (2010) Temporal requirements of insulin/IGF-1 signaling for proteotoxicity protection. Aging Cell 9, 126-134.
9. David DC, Ollikainen N, Trinidad JC, Cary MP, Burlingame AL, Kenyon C (2010) Widespread protein aggregation as an inherent part of aging in C. elegans. PLoS Biol. 8, e1000450.
10. Eremenko E, Ben-Zvi A, Morozova-Roche LA, Raveh D (2013) Aggregation of human S100A8 and S100A9 amyloidogenic proteins perturbs proteostasis in a yeast model. PLoS One 8, e58218.
11. Finley D (2009) Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu. Rev. Biochem. 78, 477-513.
12. Gerisch B, Rottiers V, Li D, Motola DL, Cummins CL, Lehrach H, Mangelsdorf DJ, Antebi A (2007) A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling. Proc. Natl Acad. Sci. USA 104, 5014-5019.
13. Ghazi A, Henis-Korenblit S, Kenyon C (2009) A transcription elongation factor that links signals from the reproductive system to lifespan extension in Caenorhabditis elegans. PLoS Genet. 5, e1000639.
14. Gidalevitz T, Ben-Zvi A, Ho KH, Brignull HR, Morimoto RI (2006) Progressive disruption of cellular protein folding in models of polyglutamine diseases. Science 311, 1471-1474.
15. Gidalevitz T, Kikis EA, Morimoto RI (2010) A cellular perspective on conformational disease: the role of genetic background and proteostasis networks. Curr. Opin. Struct. Biol. 20, 23-32.
16. Goudeau J, Bellemin S, Toselli-Mollereau E, Shamalnasab M, Chen Y, Aguilaniu H (2011) Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans. PLoS Biol. 9, e1000599.
17. Hansen M, Hsu AL, Dillin A, Kenyon C (2005) New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. PLoS Genet. 1, 119-128.
18. Haynes CM, Ron D (2010) The mitochondrial UPR - protecting organelle protein homeostasis. J. Cell Sci. 123, 3849-3855.
19. Hsin H, Kenyon C (1999) Signals from the reproductive system regulate the lifespan of C. elegans. Nature 399, 362-366.
20. Ito S, Greiss S, Gartner A, Derry WB (2010) Cell-nonautonomous regulation of C. elegans germ cell death by kri-1. Curr. Biol. 20, 333-338.
21. Lapierre LR, Gelino S, Melendez A, Hansen M (2011) Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans. Curr. Biol. 21, 1507-1514.
22. Libina N, Berman JR, Kenyon C (2003) Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan. Cell 115, 489-502.
23. Liu G, Rogers J, Murphy CT, Rongo C (2011) EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan. EMBO J. 30, 2990-3003.
24. McColl G, Rogers AN, Alavez S, Hubbard AE, Melov S, Link CD, Bush AI, Kapahi P, Lithgow GJ (2010) Insulin-like signaling determines survival during stress via posttranscriptional mechanisms in C. elegans. Cell Metab. 12, 260-272.
25. McCormick M, Chen K, Ramaswamy P, Kenyon C (2012) New genes that extend Caenorhabditis elegans' lifespan in response to reproductive signals. Aging Cell 11, 192-202.
26. Olsen A, Vantipalli MC, Lithgow GJ (2006) Checkpoint proteins control survival of the postmitotic cells in Caenorhabditis elegans. Science 312, 1381-1385.
27. Taylor RC, Dillin A (2011) Aging as an event of proteostasis collapse. Cold Spring Harb. Perspect. Biol. 3, a004440.
28. Twumasi-Boateng K, Wang TW, Tsai L, Lee KH, Salehpour A, Bhat S, Tan MW, Shapira M (2012) An age-dependent reversal in the protective capacities of JNK signaling shortens Caenorhabditis elegans lifespan. Aging Cell 11, 659-667.
29. Tyedmers J, Mogk A, Bukau B (2010) Cellular strategies for controlling protein aggregation. Nat. Rev. Mol. Cell Biol. 11, 777-788.
30. Vilchez D, Morantte I, Liu Z, Douglas PM, Merkwirth C, Rodrigues AP, Manning G, Dillin A (2012) RPN-6 determines C. elegans longevity under proteotoxic stress conditions. Nature 489, 263-268.
31. Volovik Y, Maman M, Dubnikov T, Bejerano-Sagie M, Joyce D, Kapernick EA, Cohen E, Dillin A (2012) Temporal requirements of heat shock factor-1 for longevity assurance. Aging Cell 11, 491-499.
32. Walter P, Ron D (2011) The unfolded protein response: from stress pathway to homeostatic regulation. Science 334, 1081-1086.
33. Wang MC, O'Rourke EJ, Ruvkun G (2008) Fat metabolism links germline stem cells and longevity in C. elegans. Science 322, 957-960.