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Volumn 9, Issue 3, 2013, Pages 179-189

Dysfunctional adaptive immunity during parasitic infections

Author keywords

B cell; Chronic infection; Exhaustion; Helminth; Parasite; Protozoan; T cell

Indexed keywords

ADAPTIVE IMMUNITY; B LYMPHOCYTE; CLINICAL STUDY; EXPERIMENTAL MODEL; HOST; HUMAN; IMMUNOCOMPETENT CELL; IMMUNOPATHOLOGY; IMMUNOTHERAPY; NONHUMAN; PARASITE; PARASITOSIS; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; T LYMPHOCYTE; VACCINATION;

EID: 84894034904     PISSN: 15733955     EISSN: 1875631X     Source Type: Journal    
DOI: 10.2174/1573395509666131126230832     Document Type: Review
Times cited : (14)

References (116)
  • 1
    • 84874499711 scopus 로고    scopus 로고
    • World Health Organization (WHO), Available from
    • World Health Organization (WHO). World Malaria Report 2012. 2012; Available from: http://www.who.int/malaria/publications/world_malaria_report_2012/en/
    • (2012) World Malaria Report 2012
  • 2
    • 84878883055 scopus 로고    scopus 로고
    • An Intensive Longitudinal Cohort Study of Malian Children and Adults Reveals No Evidence of Acquired Immunity to Plasmodium falciparum Infection
    • Tran TM, Li S, Doumbo S, et al. An Intensive Longitudinal Cohort Study of Malian Children and Adults Reveals No Evidence of Acquired Immunity to Plasmodium falciparum Infection. Clin Infect Dis 2013; 57(1): 40-7.
    • (2013) Clin Infect Dis , vol.57 , Issue.1 , pp. 40-47
    • Tran, T.M.1    Li, S.2    Doumbo, S.3
  • 3
    • 53749088914 scopus 로고    scopus 로고
    • Persistent parasites and immunologic memory in cutaneous leishmaniasis: Implications for vaccine designs and vaccination strategies
    • Okwor I, Uzonna J. Persistent parasites and immunologic memory in cutaneous leishmaniasis: implications for vaccine designs and vaccination strategies. Immunol Res 2008; 41(2): 123-36.
    • (2008) Immunol Res , vol.41 , Issue.2 , pp. 123-136
    • Okwor, I.1    Uzonna, J.2
  • 4
    • 84879912913 scopus 로고    scopus 로고
    • Bendiocarb resistance in Anopheles gambiae s.l. populations from Atacora department in Benin, West Africa: A threat for malaria vector control
    • Aikpon R, Agossa F, Osse R, et al. Bendiocarb resistance in Anopheles gambiae s.l. populations from Atacora department in Benin, West Africa: a threat for malaria vector control. Parasit Vectors 2013; 6: 192.
    • (2013) Parasit Vectors , vol.6 , pp. 192
    • Aikpon, R.1    Agossa, F.2    Osse, R.3
  • 5
    • 84873557949 scopus 로고    scopus 로고
    • Malaria biology and disease pathogenesis: Insights for new treatments
    • Miller LH, Ackerman HC, Su XZ, Wellems TE. Malaria biology and disease pathogenesis: insights for new treatments. Nat Med 2013; 19(2): 156-67.
    • (2013) Nat Med , vol.19 , Issue.2 , pp. 156-167
    • Miller, L.H.1    Ackerman, H.C.2    Su, X.Z.3    Wellems, T.E.4
  • 6
    • 0034780523 scopus 로고    scopus 로고
    • Antigenic variation at the infected red cell surface in malaria
    • Kyes S, Horrocks P, Newbold C. Antigenic variation at the infected red cell surface in malaria. Ann Rev Microbiol 2001; 55: 673-707.
    • (2001) Ann Rev Microbiol , vol.55 , pp. 673-707
    • Kyes, S.1    Horrocks, P.2    Newbold, C.3
  • 7
    • 84879691819 scopus 로고    scopus 로고
    • Severe malaria is associated with parasite binding to endothelial protein C receptor
    • Turner L, Lavstsen T, Berger SS, et al. Severe malaria is associated with parasite binding to endothelial protein C receptor. Nature 2013; 498(7455): 502-5.
    • (2013) Nature , vol.498 , Issue.7455 , pp. 502-505
    • Turner, L.1    Lavstsen, T.2    Berger, S.S.3
  • 8
    • 70249129419 scopus 로고    scopus 로고
    • Pathways of memory CD8+ Tcell development
    • Bannard O, Kraman M, Fearon D. Pathways of memory CD8+ Tcell development. Eur J Immunol 2009; 39(8): 2083-7.
    • (2009) Eur J Immunol , vol.39 , Issue.8 , pp. 2083-2087
    • Bannard, O.1    Kraman, M.2    Fearon, D.3
  • 10
    • 84861187675 scopus 로고    scopus 로고
    • Leishmaniasis: Vaccine candidates and perspectives
    • Singh B, Sundar S. Leishmaniasis: vaccine candidates and perspectives. Vaccine 2012; 30(26): 3834-42.
    • (2012) Vaccine , vol.30 , Issue.26 , pp. 3834-3842
    • Singh, B.1    Sundar, S.2
  • 11
    • 77956252678 scopus 로고    scopus 로고
    • Regulation of CD8+ T cell responses to infection with parasitic protozoa
    • Jordan KA, Hunter CA. Regulation of CD8+ T cell responses to infection with parasitic protozoa. Exp Parasitol 2010; 126(3): 318-25.
    • (2010) Exp Parasitol , vol.126 , Issue.3 , pp. 318-325
    • Jordan, K.A.1    Hunter, C.A.2
  • 12
    • 84871222839 scopus 로고    scopus 로고
    • Toxoplasma gondii infection and behaviour -location, location, location?
    • McConkey GA, Martin HL, Bristow GC, Webster JP. Toxoplasma gondii infection and behaviour -location, location, location? J Exp Biol 2013; 216(Pt 1): 113-9.
    • (2013) J Exp Biol , vol.216 , Issue.Pt 1 , pp. 113-119
    • McConkey, G.A.1    Martin, H.L.2    Bristow, G.C.3    Webster, J.P.4
  • 13
    • 84875066936 scopus 로고    scopus 로고
    • Determinants for the development of visceral leishmaniasis disease
    • McCall LI, Zhang WW, Matlashewski G. Determinants for the development of visceral leishmaniasis disease. PLoS pathogens 2013; 9(1): e1003053.
    • (2013) PLoS Pathogens , vol.9 , Issue.1
    • McCall, L.I.1    Zhang, W.W.2    Matlashewski, G.3
  • 14
    • 0027304299 scopus 로고
    • Gamma interferon response in secondary Leishmania major infection: Role of CD8+ T cells
    • Muller I, Kropf P, Etges RJ, Louis JA. Gamma interferon response in secondary Leishmania major infection: role of CD8+ T cells. Infect Immun 1993; 61(9): 3730-8.
    • (1993) Infect Immun , vol.61 , Issue.9 , pp. 3730-3738
    • Muller, I.1    Kropf, P.2    Etges, R.J.3    Louis, J.A.4
  • 15
    • 0023200625 scopus 로고
    • Involvement of specific Lyt-2+ T cells in the immunological control of experimentally induced murine cutaneous leishmaniasis
    • Titus RG, Milon G, Marchal G, Vassalli P, Cerottini JC, Louis JA. Involvement of specific Lyt-2+ T cells in the immunological control of experimentally induced murine cutaneous leishmaniasis. Eur J Immunol 1987; 17(10): 1429-33.
    • (1987) Eur J Immunol , vol.17 , Issue.10 , pp. 1429-1433
    • Titus, R.G.1    Milon, G.2    Marchal, G.3    Vassalli, P.4    Cerottini, J.C.5    Louis, J.A.6
  • 16
    • 0037767300 scopus 로고    scopus 로고
    • Perforin and gamma interferon are critical CD8+ T-cell-mediated responses in vaccine-induced immunity against Leishmania amazonensis infection
    • Colmenares M, Kima PE, Samoff E, Soong L, McMahon-Pratt D. Perforin and gamma interferon are critical CD8+ T-cell-mediated responses in vaccine-induced immunity against Leishmania amazonensis infection. Infect Immun 2003; 71(6): 3172-82.
    • (2003) Infect Immun , vol.71 , Issue.6 , pp. 3172-3182
    • Colmenares, M.1    Kima, P.E.2    Samoff, E.3    Soong, L.4    McMahon-Pratt, D.5
  • 17
    • 79251535587 scopus 로고    scopus 로고
    • CD4 T cells modulate expansion and survival but not functional properties of effector and memory CD8+ T cells induced by malaria sporozoites
    • Overstreet MG, Chen YC, Cockburn IA, Tse SW, Zavala F. CD4 T cells modulate expansion and survival but not functional properties of effector and memory CD8+ T cells induced by malaria sporozoites. PloS one 2011; 6(1): e15948.
    • (2011) PloS One , vol.6 , Issue.1
    • Overstreet, M.G.1    Chen, Y.C.2    Cockburn, I.A.3    Tse, S.W.4    Zavala, F.5
  • 18
    • 33845969532 scopus 로고    scopus 로고
    • Limited role for CD4+ Tcell help in the initial priming of Trypanosoma cruzi-specific CD8+ T cells
    • Padilla A, Xu D, Martin D, Tarleton R. Limited role for CD4+ Tcell help in the initial priming of Trypanosoma cruzi-specific CD8+ T cells. Infect Immun 2007; 75(1): 231-5.
    • (2007) Infect Immun , vol.75 , Issue.1 , pp. 231-235
    • Padilla, A.1    Xu, D.2    Martin, D.3    Tarleton, R.4
  • 19
    • 57549105717 scopus 로고    scopus 로고
    • Imaging effector functions of human cytotoxic CD4+ T cells specific for Plasmodium falciparum circumsporozoite protein
    • Frevert U, Moreno A, Calvo-Calle JM, Klotz C, Nardin E. Imaging effector functions of human cytotoxic CD4+ T cells specific for Plasmodium falciparum circumsporozoite protein. Int J Parasitol 2009; 39(1): 119-32.
    • (2009) Int J Parasitol , vol.39 , Issue.1 , pp. 119-132
    • Frevert, U.1    Moreno, A.2    Calvo-Calle, J.M.3    Klotz, C.4    Nardin, E.5
  • 20
    • 84865386747 scopus 로고    scopus 로고
    • Characterization of CD4(+) cytotoxic lymphocytes and apoptosis markers induced by Trypanossoma cruzi infection
    • Keesen TS, Gomes JA, Fares RC, et al. Characterization of CD4(+) cytotoxic lymphocytes and apoptosis markers induced by Trypanossoma cruzi infection. Scand J Immunol 2012; 76(3): 311-9.
    • (2012) Scand J Immunol , vol.76 , Issue.3 , pp. 311-319
    • Keesen, T.S.1    Gomes, J.A.2    Fares, R.C.3
  • 21
    • 0029820279 scopus 로고    scopus 로고
    • CD4-mediated and CD8-mediated cytotoxic and proliferative immune responses to Toxoplasma gondii in seropositive humans
    • Purner MB, Berens RL, Nash PB, et al. CD4-mediated and CD8-mediated cytotoxic and proliferative immune responses to Toxoplasma gondii in seropositive humans. Infect Immun 1996; 64(10): 4330-8.
    • (1996) Infect Immun , vol.64 , Issue.10 , pp. 4330-4338
    • Purner, M.B.1    Berens, R.L.2    Nash, P.B.3
  • 22
    • 0025777095 scopus 로고
    • Age-dependent acquired protection against Plasmodium falciparum in people having two years exposure to hyperendemic malaria
    • Baird JK, Jones TR, Danudirgo EW, et al. Age-dependent acquired protection against Plasmodium falciparum in people having two years exposure to hyperendemic malaria. Am J Trop Med Hyg 1991; 45(1): 65-76.
    • (1991) Am J Trop Med Hyg , vol.45 , Issue.1 , pp. 65-76
    • Baird, J.K.1    Jones, T.R.2    Danudirgo, E.W.3
  • 23
    • 0032977856 scopus 로고    scopus 로고
    • Immunity to non-cerebral severe malaria is acquired after one or two infections
    • Gupta S, Snow RW, Donnelly CA, Marsh K, Newbold C. Immunity to non-cerebral severe malaria is acquired after one or two infections. Nat Med 1999; 5(3): 340-3.
    • (1999) Nat Med , vol.5 , Issue.3 , pp. 340-343
    • Gupta, S.1    Snow, R.W.2    Donnelly, C.A.3    Marsh, K.4    Newbold, C.5
  • 24
    • 8144224632 scopus 로고
    • Gamma-globulin and acquired immunity to human malaria
    • Cohen S, Mc GI, Carrington S. Gamma-globulin and acquired immunity to human malaria. Nature 1961; 192: 733-7.
    • (1961) Nature , vol.192 , pp. 733-737
    • Cohen, S.1    Mc, G.I.2    Carrington, S.3
  • 25
    • 44949219210 scopus 로고    scopus 로고
    • Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses
    • Radwanska M, Guirnalda P, De Trez C, Ryffel B, Black S, Magez S. Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses. PLoS Pathogens 2008; 4(5): e1000078.
    • (2008) PLoS Pathogens , vol.4 , Issue.5
    • Radwanska, M.1    Guirnalda, P.2    de Trez, C.3    Ryffel, B.4    Black, S.5    Magez, S.6
  • 26
    • 79952675131 scopus 로고    scopus 로고
    • Follicular helper CD4 T cells (TFH)
    • Crotty S. Follicular helper CD4 T cells (TFH). Ann Review Immunol 2011; 29: 621-63.
    • (2011) Ann Review Immunol , vol.29 , pp. 621-663
    • Crotty, S.1
  • 27
    • 0034161721 scopus 로고    scopus 로고
    • Decreased resistance of B celldeficient mice to infection with Toxoplasma gondii despite unimpaired expression of IFN-gamma, TNF-alpha, and inducible nitric oxide synthase
    • Kang H, Remington JS, Suzuki Y. Decreased resistance of B celldeficient mice to infection with Toxoplasma gondii despite unimpaired expression of IFN-gamma, TNF-alpha, and inducible nitric oxide synthase. J Immunol 2000; 164(5): 2629-34.
    • (2000) J Immunol , vol.164 , Issue.5 , pp. 2629-2634
    • Kang, H.1    Remington, J.S.2    Suzuki, Y.3
  • 28
    • 53349139166 scopus 로고    scopus 로고
    • Polyclonal and specific antibodies mediate protective immunity against enteric helminth infection
    • McCoy KD, Stoel M, Stettler R, et al. Polyclonal and specific antibodies mediate protective immunity against enteric helminth infection. Cell Host Microbe 2008; 4(4): 362-73.
    • (2008) Cell Host Microbe , vol.4 , Issue.4 , pp. 362-373
    • McCoy, K.D.1    Stoel, M.2    Stettler, R.3
  • 29
    • 61949121872 scopus 로고    scopus 로고
    • Cytokineproducing effector B cells regulate type 2 immunity to H. polygyrus
    • Wojciechowski W, Harris DP, Sprague F, et al. Cytokineproducing effector B cells regulate type 2 immunity to H. polygyrus. Immunity 2009; 30(3): 421-33.
    • (2009) Immunity , vol.30 , Issue.3 , pp. 421-433
    • Wojciechowski, W.1    Harris, D.P.2    Sprague, F.3
  • 30
    • 0036138364 scopus 로고    scopus 로고
    • Deficient humoral responses underlie susceptibility to Toxoplasma gondii in CD4-deficient mice
    • Johnson LL, Sayles PC. Deficient humoral responses underlie susceptibility to Toxoplasma gondii in CD4-deficient mice. Infect Immun 2002; 70(1): 185-91.
    • (2002) Infect Immun , vol.70 , Issue.1 , pp. 185-191
    • Johnson, L.L.1    Sayles, P.C.2
  • 31
    • 0032539562 scopus 로고    scopus 로고
    • A role for B cells in the development of T cell helper function in a malaria infection in mice
    • Langhorne J, Cross C, Seixas E, Li C, von der Weid T. A role for B cells in the development of T cell helper function in a malaria infection in mice. Proc Natl Acad Sci USA 1998; 95(4): 1730-4.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.4 , pp. 1730-1734
    • Langhorne, J.1    Cross, C.2    Seixas, E.3    Li, C.4    von der Weid, T.5
  • 32
    • 0030001823 scopus 로고    scopus 로고
    • Gene-targeted mice lacking B cells are unable to eliminate a blood stage malaria infection
    • von der Weid T, Honarvar N, Langhorne J. Gene-targeted mice lacking B cells are unable to eliminate a blood stage malaria infection. J Immunol 1996; 156(7): 2510-6.
    • (1996) J Immunol , vol.156 , Issue.7 , pp. 2510-2516
    • von der Weid, T.1    Honarvar, N.2    Langhorne, J.3
  • 33
    • 0019405319 scopus 로고
    • Immunity to Plasmodium chabaudi adami in the B-cell-deficient mouse
    • Grun JL, Weidanz WP. Immunity to Plasmodium chabaudi adami in the B-cell-deficient mouse. Nature 1981; 290(5802): 143-5.
    • (1981) Nature , vol.290 , Issue.5802 , pp. 143-145
    • Grun, J.L.1    Weidanz, W.P.2
  • 34
    • 84862761006 scopus 로고    scopus 로고
    • Immune markers and correlates of protection for vaccine induced immune responses
    • Thakur A, Pedersen LE, Jungersen G. Immune markers and correlates of protection for vaccine induced immune responses. Vaccine 2012; 30(33): 4907-20.
    • (2012) Vaccine , vol.30 , Issue.33 , pp. 4907-4920
    • Thakur, A.1    Pedersen, L.E.2    Jungersen, G.3
  • 35
    • 79956077563 scopus 로고    scopus 로고
    • T cell exhaustion
    • Wherry EJ. T cell exhaustion. Nat Immunol 2011; 12(6): 492-9.
    • (2011) Nat Immunol , vol.12 , Issue.6 , pp. 492-499
    • Wherry, E.J.1
  • 36
    • 0032416085 scopus 로고    scopus 로고
    • Viral immune evasion due to persistence of activated T cells without effector function
    • Zajac AJ, Blattman JN, Murali-Krishna K, et al. Viral immune evasion due to persistence of activated T cells without effector function. J Exp Med 1998; 188(12): 2205-13.
    • (1998) J Exp Med , vol.188 , Issue.12 , pp. 2205-2213
    • Zajac, A.J.1    Blattman, J.N.2    Murali-Krishna, K.3
  • 37
    • 0032482176 scopus 로고    scopus 로고
    • Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes
    • Gallimore A, Glithero A, Godkin A, et al. Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes. J Exp Med 1998; 187(9): 1383-93.
    • (1998) J Exp Med , vol.187 , Issue.9 , pp. 1383-1393
    • Gallimore, A.1    Glithero, A.2    Godkin, A.3
  • 38
    • 0037221289 scopus 로고    scopus 로고
    • Ablation of CD8 and CD4 T cell responses by high viral loads
    • Fuller MJ, Zajac AJ. Ablation of CD8 and CD4 T cell responses by high viral loads. J Immunol 2003; 170(1): 477-86.
    • (2003) J Immunol , vol.170 , Issue.1 , pp. 477-486
    • Fuller, M.J.1    Zajac, A.J.2
  • 39
    • 0037383592 scopus 로고    scopus 로고
    • Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
    • Wherry EJ, Blattman JN, Murali-Krishna K, van der Most R, Ahmed R. Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J Virol 2003; 77(8): 4911-27.
    • (2003) J Virol , vol.77 , Issue.8 , pp. 4911-4927
    • Wherry, E.J.1    Blattman, J.N.2    Murali-Krishna, K.3    van der Most, R.4    Ahmed, R.5
  • 41
    • 34247884612 scopus 로고    scopus 로고
    • The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
    • Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol 2007; 8(3): 239-45.
    • (2007) Nat Immunol , vol.8 , Issue.3 , pp. 239-245
    • Sharpe, A.H.1    Wherry, E.J.2    Ahmed, R.3    Freeman, G.J.4
  • 42
    • 65349119978 scopus 로고    scopus 로고
    • CD28 and CTLA-4 coreceptor expression and signal transduction
    • Rudd CE, Taylor A, Schneider H. CD28 and CTLA-4 coreceptor expression and signal transduction. Immunol Rev 2009; 229(1): 12-26.
    • (2009) Immunol Rev , vol.229 , Issue.1 , pp. 12-26
    • Rudd, C.E.1    Taylor, A.2    Schneider, H.3
  • 43
    • 79953709110 scopus 로고    scopus 로고
    • Regulation of inflammation, autoimmunity, and infection immunity by HVEMBTLA signaling
    • Shui JW, Steinberg MW, Kronenberg M. Regulation of inflammation, autoimmunity, and infection immunity by HVEMBTLA signaling. J leukocyte Biol 2011; 89(4): 517-23.
    • (2011) J Leukocyte Biol , vol.89 , Issue.4 , pp. 517-523
    • Shui, J.W.1    Steinberg, M.W.2    Kronenberg, M.3
  • 44
    • 84860898062 scopus 로고    scopus 로고
    • The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology
    • Hafalla JC, Claser C, Couper KN, et al. The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. PLoS pathogens. 2012; 8(2): e1002504.
    • (2012) PLoS Pathogens , vol.8 , Issue.2
    • Hafalla, J.C.1    Claser, C.2    Couper, K.N.3
  • 45
    • 60149107060 scopus 로고    scopus 로고
    • Behavior of parasite-specific effector CD8+ T cells in the brain and visualization of a kinesisassociated system of reticular fibers
    • Wilson EH, Harris TH, Mrass P, et al. Behavior of parasite-specific effector CD8+ T cells in the brain and visualization of a kinesisassociated system of reticular fibers. Immunity 2009; 30(2): 300-11.
    • (2009) Immunity , vol.30 , Issue.2 , pp. 300-311
    • Wilson, E.H.1    Harris, T.H.2    Mrass, P.3
  • 46
    • 84884235549 scopus 로고    scopus 로고
    • Donor CD8 T cells prevent Toxoplasma de-encystation but fail to rescue exhausted endogenous CD8 population
    • Bhadra R, Cobb DA, Khan IA. Donor CD8 T cells prevent Toxoplasma de-encystation but fail to rescue exhausted endogenous CD8 population. Infect Immun 2013; 81(9): 3414-25.
    • (2013) Infect Immun , vol.81 , Issue.9 , pp. 3414-3425
    • Bhadra, R.1    Cobb, D.A.2    Khan, I.A.3
  • 47
    • 84861536242 scopus 로고    scopus 로고
    • PD-1-mediated attrition of polyfunctional memory CD8+ T cells in chronic toxoplasma infection
    • Bhadra R, Gigley JP, Khan IA. PD-1-mediated attrition of polyfunctional memory CD8+ T cells in chronic toxoplasma infection. J Infect Dis 2012; 206(1): 125-34.
    • (2012) J Infect Dis , vol.206 , Issue.1 , pp. 125-134
    • Bhadra, R.1    Gigley, J.P.2    Khan, I.A.3
  • 48
    • 79959357729 scopus 로고    scopus 로고
    • Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade
    • Bhadra R, Gigley JP, Weiss LM, Khan IA. Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade. Proc Natl Acad Sci USA 2011; 108(22): 9196-201.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.22 , pp. 9196-9201
    • Bhadra, R.1    Gigley, J.P.2    Weiss, L.M.3    Khan, I.A.4
  • 49
    • 84868113488 scopus 로고    scopus 로고
    • Redefining chronic toxoplasmosis-a T cell exhaustion perspective
    • Bhadra R, Khan IA. Redefining chronic toxoplasmosis-a T cell exhaustion perspective. PLoS pathogens 2012; 8(10): e1002903.
    • (2012) PLoS Pathogens , vol.8 , Issue.10
    • Bhadra, R.1    Khan, I.A.2
  • 50
    • 78649797454 scopus 로고    scopus 로고
    • CD8 cells of patients with diffuse cutaneous leishmaniasis display functional exhaustion: The latter is reversed, in vitro, by TLR2 agonists
    • Hernandez-Ruiz J, Salaiza-Suazo N, Carrada G, et al. CD8 cells of patients with diffuse cutaneous leishmaniasis display functional exhaustion: the latter is reversed, in vitro, by TLR2 agonists. PLoS Negl Trop Dis 2010; 4(11): e871.
    • (2010) PLoS Negl Trop Dis , vol.4 , Issue.11
    • Hernandez-Ruiz, J.1    Salaiza-Suazo, N.2    Carrada, G.3
  • 51
    • 84875455887 scopus 로고    scopus 로고
    • Parasite-derived arginase influences secondary anti-Leishmania immunity by regulating programmed cell death-1-mediated CD4+ T cell exhaustion
    • Mou Z, Muleme HM, Liu D, et al. Parasite-derived arginase influences secondary anti-Leishmania immunity by regulating programmed cell death-1-mediated CD4+ T cell exhaustion. J Immunol 2013; 190(7): 3380-9.
    • (2013) J Immunol , vol.190 , Issue.7 , pp. 3380-3389
    • Mou, Z.1    Muleme, H.M.2    Liu, D.3
  • 52
    • 0037369719 scopus 로고    scopus 로고
    • Cutting edge: Dysfunctional CD8+ T cells reside in nonlymphoid tissues during chronic Trypanosoma cruzi infection
    • Leavey JK, Tarleton RL. Cutting edge: dysfunctional CD8+ T cells reside in nonlymphoid tissues during chronic Trypanosoma cruzi infection. J Immunol 2003; 170(5): 2264-8.
    • (2003) J Immunol , vol.170 , Issue.5 , pp. 2264-2268
    • Leavey, J.K.1    Tarleton, R.L.2
  • 53
    • 84871349098 scopus 로고    scopus 로고
    • Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas disease
    • Arguello RJ, Albareda MC, Alvarez MG, et al. Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas disease. PloS one 2012; 7(5): e35966.
    • (2012) PloS One , vol.7 , Issue.5
    • Arguello, R.J.1    Albareda, M.C.2    Alvarez, M.G.3
  • 54
    • 33644698263 scopus 로고    scopus 로고
    • Trypanosoma cruzi modulates the profile of memory CD8+ T cells in chronic Chagas' disease patients
    • Albareda MC, Laucella SA, Alvarez MG, et al. Trypanosoma cruzi modulates the profile of memory CD8+ T cells in chronic Chagas' disease patients. Int Immunol 2006; 18(3): 465-71.
    • (2006) Int Immunol , vol.18 , Issue.3 , pp. 465-471
    • Albareda, M.C.1    Laucella, S.A.2    Alvarez, M.G.3
  • 55
    • 81455131796 scopus 로고    scopus 로고
    • B and T lymphocyte attenuator restricts the protective immune response against experimental malaria
    • Adler G, Steeg C, Pfeffer K, et al. B and T lymphocyte attenuator restricts the protective immune response against experimental malaria. J Immunol 2011; 187(10): 5310-9.
    • (2011) J Immunol , vol.187 , Issue.10 , pp. 5310-5319
    • Adler, G.1    Steeg, C.2    Pfeffer, K.3
  • 56
    • 84855911057 scopus 로고    scopus 로고
    • Therapeutic blockade of PDL1 and LAG-3 rapidly clears established blood-stage Plasmodium infection
    • Butler NS, Moebius J, Pewe LL, et al. Therapeutic blockade of PDL1 and LAG-3 rapidly clears established blood-stage Plasmodium infection. Nat Immunol 2012; 13(2): 188-95.
    • (2012) Nat Immunol , vol.13 , Issue.2 , pp. 188-195
    • Butler, N.S.1    Moebius, J.2    Pewe, L.L.3
  • 57
    • 84872737389 scopus 로고    scopus 로고
    • Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion
    • Illingworth J, Butler NS, Roetynck S, et al. Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion. J Immunol 2013; 190(3): 1038-47.
    • (2013) J Immunol , vol.190 , Issue.3 , pp. 1038-1047
    • Illingworth, J.1    Butler, N.S.2    Roetynck, S.3
  • 58
    • 0037442134 scopus 로고    scopus 로고
    • CTLA-4 in filarial infections: Implications for a role in diminished T cell reactivity
    • Steel C, Nutman TB. CTLA-4 in filarial infections: implications for a role in diminished T cell reactivity. J Immunol 2003; 170(4): 1930-8.
    • (2003) J Immunol , vol.170 , Issue.4 , pp. 1930-1938
    • Steel, C.1    Nutman, T.B.2
  • 59
    • 40949164727 scopus 로고    scopus 로고
    • CTLA-4 and CD4+ CD25+ regulatory T cells inhibit protective immunity to filarial parasites in vivo
    • Taylor MD, Harris A, Babayan SA, et al. CTLA-4 and CD4+ CD25+ regulatory T cells inhibit protective immunity to filarial parasites in vivo. J Immunol 2007; 179(7): 4626-34.
    • (2007) J Immunol , vol.179 , Issue.7 , pp. 4626-4634
    • Taylor, M.D.1    Harris, A.2    Babayan, S.A.3
  • 60
    • 84875969772 scopus 로고    scopus 로고
    • Th2 cell-intrinsic hypo-responsiveness determines susceptibility to helminth infection
    • van der Werf N, Redpath SA, Azuma M, Yagita H, Taylor MD. Th2 cell-intrinsic hypo-responsiveness determines susceptibility to helminth infection. PLoS Pathogens 2013; 9(3): e1003215.
    • (2013) PLoS Pathogens , vol.9 , Issue.3
    • van der Werf, N.1    Redpath, S.A.2    Azuma, M.3    Yagita, H.4    Taylor, M.D.5
  • 61
    • 65249145164 scopus 로고    scopus 로고
    • Th2 cell hyporesponsiveness during chronic murine schistosomiasis is cell intrinsic and linked to GRAIL expression
    • Taylor JJ, Krawczyk CM, Mohrs M, Pearce EJ. Th2 cell hyporesponsiveness during chronic murine schistosomiasis is cell intrinsic and linked to GRAIL expression. J Clin Invest 2009; 119(4): 1019-28.
    • (2009) J Clin Invest , vol.119 , Issue.4 , pp. 1019-1028
    • Taylor, J.J.1    Krawczyk, C.M.2    Mohrs, M.3    Pearce, E.J.4
  • 62
    • 84867176113 scopus 로고    scopus 로고
    • Helminth infections and host immune regulation
    • McSorley HJ, Maizels RM. Helminth infections and host immune regulation. Clin Microbiol Rev 2012; 25(4): 585-608.
    • (2012) Clin Microbiol Rev , vol.25 , Issue.4 , pp. 585-608
    • McSorley, H.J.1    Maizels, R.M.2
  • 63
    • 34548680261 scopus 로고    scopus 로고
    • Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction
    • Kaufmann DE, Kavanagh DG, Pereyra F, et al. Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction. Nat Immunol 2007; 8(11): 1246-54.
    • (2007) Nat Immunol , vol.8 , Issue.11 , pp. 1246-1254
    • Kaufmann, D.E.1    Kavanagh, D.G.2    Pereyra, F.3
  • 64
    • 61449181280 scopus 로고    scopus 로고
    • Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade
    • Nakamoto N, Cho H, Shaked A, et al. Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade. PLoS Pathogens 2009; 5(2): e1000313.
    • (2009) PLoS Pathogens , vol.5 , Issue.2
    • Nakamoto, N.1    Cho, H.2    Shaked, A.3
  • 65
    • 38349149016 scopus 로고    scopus 로고
    • CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator
    • Cai G, Anumanthan A, Brown JA, Greenfield EA, Zhu B, Freeman GJ. CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator. Nat Immunol 2008; 9(2): 176-85.
    • (2008) Nat Immunol , vol.9 , Issue.2 , pp. 176-185
    • Cai, G.1    Anumanthan, A.2    Brown, J.A.3    Greenfield, E.A.4    Zhu, B.5    Freeman, G.J.6
  • 66
    • 80555149919 scopus 로고    scopus 로고
    • Cutting edge: CD40-CD40 ligand pathway plays a critical CD8-intrinsic and -extrinsic role during rescue of exhausted CD8 T cells
    • Bhadra R, Gigley JP, Khan IA. Cutting edge: CD40-CD40 ligand pathway plays a critical CD8-intrinsic and -extrinsic role during rescue of exhausted CD8 T cells. J Immunol 2011; 187(9): 4421-5.
    • (2011) J Immunol , vol.187 , Issue.9 , pp. 4421-4425
    • Bhadra, R.1    Gigley, J.P.2    Khan, I.A.3
  • 67
    • 84878585947 scopus 로고    scopus 로고
    • PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells
    • West EE, Jin HT, Rasheed AU, et al. PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells. J Clin Invest 2013; 123(6): 2604-15.
    • (2013) J Clin Invest , vol.123 , Issue.6 , pp. 2604-2615
    • West, E.E.1    Jin, H.T.2    Rasheed, A.U.3
  • 68
    • 67649203681 scopus 로고    scopus 로고
    • A vital role for interleukin-21 in the control of a chronic viral infection
    • Yi JS, Du M, Zajac AJ. A vital role for interleukin-21 in the control of a chronic viral infection. Science 2009; 324(5934): 1572-6.
    • (2009) Science , vol.324 , Issue.5934 , pp. 1572-1576
    • Yi, J.S.1    Du, M.2    Zajac, A.J.3
  • 69
    • 79960592524 scopus 로고    scopus 로고
    • TLRs innate immunereceptors and Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) CIDR1alpha-driven human polyclonal B-cell activation
    • Simone O, Bejarano MT, Pierce SK, et al. TLRs innate immunereceptors and Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) CIDR1alpha-driven human polyclonal B-cell activation. Acta tropica 2011; 119(2-3): 144-50.
    • (2011) Acta Tropica , vol.119 , Issue.2-3 , pp. 144-150
    • Simone, O.1    Bejarano, M.T.2    Pierce, S.K.3
  • 70
    • 33747796656 scopus 로고    scopus 로고
    • Increased B cell survival and preferential activation of the memory compartment by a malaria polyclonal B cell activator
    • Donati D, Mok B, Chene A, et al. Increased B cell survival and preferential activation of the memory compartment by a malaria polyclonal B cell activator. J Immunol 2006; 177(5): 3035-44.
    • (2006) J Immunol , vol.177 , Issue.5 , pp. 3035-3044
    • Donati, D.1    Mok, B.2    Chene, A.3
  • 71
    • 0033805081 scopus 로고    scopus 로고
    • Albendazole treatment of children with ascariasis enhances the vibriocidal antibody response to the live attenuated oral cholera vaccine CVD 103-HgR
    • Cooper PJ, Chico ME, Losonsky G, et al. Albendazole treatment of children with ascariasis enhances the vibriocidal antibody response to the live attenuated oral cholera vaccine CVD 103-HgR. J Infect Dis 2000; 182(4): 1199-206.
    • (2000) J Infect Dis , vol.182 , Issue.4 , pp. 1199-1206
    • Cooper, P.J.1    Chico, M.E.2    Losonsky, G.3
  • 72
    • 0031657079 scopus 로고    scopus 로고
    • Impaired tetanus-specific cellular and humoral responses following tetanus vaccination in human onchocerciasis: A possible role for interleukin-10
    • Cooper PJ, Espinel I, Paredes W, Guderian RH, Nutman TB. Impaired tetanus-specific cellular and humoral responses following tetanus vaccination in human onchocerciasis: a possible role for interleukin-10. J Infect Dis 1998; 178(4): 1133-8.
    • (1998) J Infect Dis , vol.178 , Issue.4 , pp. 1133-1138
    • Cooper, P.J.1    Espinel, I.2    Paredes, W.3    Guderian, R.H.4    Nutman, T.B.5
  • 73
    • 2142755888 scopus 로고    scopus 로고
    • Impairment of tetanus-specific cellular and humoral responses following tetanus vaccination in human lymphatic filariasis
    • Nookala S, Srinivasan S, Kaliraj P, Narayanan RB, Nutman TB. Impairment of tetanus-specific cellular and humoral responses following tetanus vaccination in human lymphatic filariasis. Infect Immun 2004; 72(5): 2598-604.
    • (2004) Infect Immun , vol.72 , Issue.5 , pp. 2598-2604
    • Nookala, S.1    Srinivasan, S.2    Kaliraj, P.3    Narayanan, R.B.4    Nutman, T.B.5
  • 74
    • 84876854461 scopus 로고    scopus 로고
    • How malaria modulates memory: Activation and dysregulation of B cells in Plasmodium infection
    • Scholzen A, Sauerwein RW. How malaria modulates memory: activation and dysregulation of B cells in Plasmodium infection. Trends Parasitol 2013; 29(5): 252-62.
    • (2013) Trends Parasitol , vol.29 , Issue.5 , pp. 252-262
    • Scholzen, A.1    Sauerwein, R.W.2
  • 75
    • 68149164395 scopus 로고    scopus 로고
    • Atypical memory B cells are greatly expanded in individuals living in a malaria-endemic area
    • Weiss GE, Crompton PD, Li S, et al. Atypical memory B cells are greatly expanded in individuals living in a malaria-endemic area. J Immunol 2009; 183(3): 2176-82.
    • (2009) J Immunol , vol.183 , Issue.3 , pp. 2176-2182
    • Weiss, G.E.1    Crompton, P.D.2    Li, S.3
  • 76
    • 46049112339 scopus 로고    scopus 로고
    • Evidence for HIVassociated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals
    • Moir S, Ho J, Malaspina A, Wang W, et al. Evidence for HIVassociated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. J Exp Med 2008; 205(8): 1797-805.
    • (2008) J Exp Med , vol.205 , Issue.8 , pp. 1797-1805
    • Moir, S.1    Ho, J.2    Malaspina, A.3    Wang, W.4
  • 77
    • 83455210370 scopus 로고    scopus 로고
    • FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling
    • Sohn HW, Krueger PD, Davis RS, Pierce SK. FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling. Blood 2011; 118(24): 6332-41.
    • (2011) Blood , vol.118 , Issue.24 , pp. 6332-6341
    • Sohn, H.W.1    Krueger, P.D.2    Davis, R.S.3    Pierce, S.K.4
  • 79
    • 35349014587 scopus 로고    scopus 로고
    • Molecular signature of CD8+ T cell exhaustion during chronic viral infection
    • Wherry EJ, Ha SJ, Kaech SM, et al. Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity 2007; 27(4): 670-84.
    • (2007) Immunity , vol.27 , Issue.4 , pp. 670-684
    • Wherry, E.J.1    Ha, S.J.2    Kaech, S.M.3
  • 80
    • 84874572370 scopus 로고    scopus 로고
    • Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies
    • Muellenbeck MF, Ueberheide B, Amulic B, et al. Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies. J Exp Med 2013; 210(2): 389-99.
    • (2013) J Exp Med , vol.210 , Issue.2 , pp. 389-399
    • Muellenbeck, M.F.1    Ueberheide, B.2    Amulic, B.3
  • 81
    • 79959220130 scopus 로고    scopus 로고
    • Acute Disruption of Bone Marrow B Lymphopoiesis and Apoptosis of Transitional and Marginal Zone B Cells in the Spleen following a Blood-Stage Plasmodium chabaudi Infection in Mice
    • Bockstal V, Geurts N, Magez S. Acute Disruption of Bone Marrow B Lymphopoiesis and Apoptosis of Transitional and Marginal Zone B Cells in the Spleen following a Blood-Stage Plasmodium chabaudi Infection in Mice. J Parasitol Res 2011; 2011: 534697.
    • (2011) J Parasitol Res 2011 , pp. 534697
    • Bockstal, V.1    Geurts, N.2    Magez, S.3
  • 82
    • 79959833610 scopus 로고    scopus 로고
    • T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis
    • Bockstal V, Guirnalda P, Caljon G, et al. T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis. PLoS Pathogens 2011; 7(6): e1002089.
    • (2011) PLoS Pathogens , vol.7 , Issue.6
    • Bockstal, V.1    Guirnalda, P.2    Caljon, G.3
  • 83
    • 34447559900 scopus 로고    scopus 로고
    • Trypanosoma cruzi infection beats the B-cell compartment favouring parasite establishment: Can we strike first?
    • Acosta Rodriguez EV, Zuniga EI, Montes CL, et al. Trypanosoma cruzi infection beats the B-cell compartment favouring parasite establishment: can we strike first? Scand J Immunol 2007; 66(2-3): 137-42.
    • (2007) Scand J Immunol , vol.66 , Issue.2-3 , pp. 137-142
    • Acosta Rodriguez, E.V.1    Zuniga, E.I.2    Montes, C.L.3
  • 84
    • 0017684542 scopus 로고
    • Suppressor cells and loss of B-cell potential in mice infected with Trypanosoma brucei
    • Corsini AC, Clayton C, Askonas BA, Ogilvie BM. Suppressor cells and loss of B-cell potential in mice infected with Trypanosoma brucei. Clin Exp Immunol 1977; 29(1): 122-31.
    • (1977) Clin Exp Immunol , vol.29 , Issue.1 , pp. 122-131
    • Corsini, A.C.1    Clayton, C.2    Askonas, B.A.3    Ogilvie, B.M.4
  • 85
    • 66149190937 scopus 로고    scopus 로고
    • Molecular orchestration of differentiation and function of regulatory T cells
    • Lu LF, Rudensky A. Molecular orchestration of differentiation and function of regulatory T cells. Genes Dev 2009; 23(11): 1270-82.
    • (2009) Genes Dev , vol.23 , Issue.11 , pp. 1270-1282
    • Lu, L.F.1    Rudensky, A.2
  • 86
    • 84883772994 scopus 로고    scopus 로고
    • Role of cytokines in thymus-versus peripherally derived-regulatory T cell differentiation and function
    • Goldstein JD, Perol L, Zaragoza B, Baeyens A, Marodon G, Piaggio E. Role of cytokines in thymus-versus peripherally derived-regulatory T cell differentiation and function. Front Immunol 2013; 4: 155.
    • (2013) Front Immunol , vol.4 , pp. 155
    • Goldstein, J.D.1    Perol, L.2    Zaragoza, B.3    Baeyens, A.4    Marodon, G.5    Piaggio, E.6
  • 87
    • 33745074981 scopus 로고    scopus 로고
    • Signals required for programming effector and memory development by CD8+ T cells
    • Mescher MF, Curtsinger JM, Agarwal P, et al. Signals required for programming effector and memory development by CD8+ T cells. Immunol Rev 2006; 211: 81-92.
    • (2006) Immunol Rev , vol.211 , pp. 81-92
    • Mescher, M.F.1    Curtsinger, J.M.2    Agarwal, P.3
  • 88
    • 66349085903 scopus 로고    scopus 로고
    • Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria
    • Walther M, Jeffries D, Finney OC, et al. Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria. PLoS Pathogens 2009; 5(4): e1000364.
    • (2009) PLoS Pathogens , vol.5 , Issue.4
    • Walther, M.1    Jeffries, D.2    Finney, O.C.3
  • 89
    • 66349138519 scopus 로고    scopus 로고
    • Parasite-dependent expansion of TNF receptor II-positive regulatory T cells with enhanced suppressive activity in adults with severe malaria
    • Minigo G, Woodberry T, Piera KA, et al. Parasite-dependent expansion of TNF receptor II-positive regulatory T cells with enhanced suppressive activity in adults with severe malaria. PLoS Pathogens 2009; 5(4): e1000402.
    • (2009) PLoS Pathogens , vol.5 , Issue.4
    • Minigo, G.1    Woodberry, T.2    Piera, K.A.3
  • 90
    • 64249129200 scopus 로고    scopus 로고
    • Anti-CD25 antibody-mediated depletion of effector T cell populations enhances susceptibility of mice to acute but not chronic Toxoplasma gondii infection
    • Couper KN, Lanthier PA, Perona-Wright G, et al. Anti-CD25 antibody-mediated depletion of effector T cell populations enhances susceptibility of mice to acute but not chronic Toxoplasma gondii infection. J Immunol 2009; 182(7): 3985-94.
    • (2009) J Immunol , vol.182 , Issue.7 , pp. 3985-3994
    • Couper, K.N.1    Lanthier, P.A.2    Perona-Wright, G.3
  • 91
    • 84866483591 scopus 로고    scopus 로고
    • The cytokines interleukin 27 and interferon-gamma promote distinct Treg cell populations required to limit infection-induced pathology
    • Hall AO, Beiting DP, Tato C, et al. The cytokines interleukin 27 and interferon-gamma promote distinct Treg cell populations required to limit infection-induced pathology. Immunity 2012; 37(3): 511-23.
    • (2012) Immunity , vol.37 , Issue.3 , pp. 511-523
    • Hall, A.O.1    Beiting, D.P.2    Tato, C.3
  • 92
    • 84867150475 scopus 로고    scopus 로고
    • Induction of IL-10-producing CD1dhighCD5+ regulatory B cells following Babesia microti-infection
    • Jeong YI, Hong SH, Cho SH, Lee WJ, Lee SE. Induction of IL-10-producing CD1dhighCD5+ regulatory B cells following Babesia microti-infection. PloS one 2012; 7(10): e46553.
    • (2012) PloS One , vol.7 , Issue.10
    • Jeong, Y.I.1    Hong, S.H.2    Cho, S.H.3    Lee, W.J.4    Lee, S.E.5
  • 93
    • 84872826792 scopus 로고    scopus 로고
    • Development of adult worms and granulomatous pathology are collectively regulated by T-and Bcells in mice infected with Schistosoma japonicum
    • Tang H, Ming Z, Liu R, et al. Development of adult worms and granulomatous pathology are collectively regulated by T-and Bcells in mice infected with Schistosoma japonicum. PloS one 2013; 8(1): e54432.
    • (2013) PloS One , vol.8 , Issue.1
    • Tang, H.1    Ming, Z.2    Liu, R.3
  • 94
    • 84888074455 scopus 로고    scopus 로고
    • Role of IL-10-producing regulatory B cells in control of cerebral malaria in Plasmodium berghei infected mice
    • Liu Y, Chen Y, Li Z, et al. Role of IL-10-producing regulatory B cells in control of cerebral malaria in Plasmodium berghei infected mice. Eur J Immunol 2013; 43(11): 2907-18.
    • (2013) Eur J Immunol , vol.43 , Issue.11 , pp. 2907-2918
    • Liu, Y.1    Chen, Y.2    Li, Z.3
  • 96
    • 0036535490 scopus 로고    scopus 로고
    • The mechanism and significance of deletion of parasite-specific CD4(+) T cells in malaria infection
    • Xu H, Wipasa J, Yan H, et al. The mechanism and significance of deletion of parasite-specific CD4(+) T cells in malaria infection. J Exp Med 2002; 195(7): 881-92.
    • (2002) J Exp Med , vol.195 , Issue.7 , pp. 881-892
    • Xu, H.1    Wipasa, J.2    Yan, H.3
  • 97
    • 0035478642 scopus 로고    scopus 로고
    • Apoptotic deletion of Th cells specific for the 19-kDa carboxyl-terminal fragment of merozoite surface protein 1 during malaria infection
    • Wipasa J, Xu H, Stowers A, Good MF. Apoptotic deletion of Th cells specific for the 19-kDa carboxyl-terminal fragment of merozoite surface protein 1 during malaria infection. J Immunol 2001; 167(7): 3903-9.
    • (2001) J Immunol , vol.167 , Issue.7 , pp. 3903-3909
    • Wipasa, J.1    Xu, H.2    Stowers, A.3    Good, M.F.4
  • 98
    • 84884214616 scopus 로고    scopus 로고
    • Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria
    • Pinzon-Charry A, Woodberry T, Kienzloe V, et al. Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria. J Exp Med 2013; 210(8): 1635-46.
    • (2013) J Exp Med , vol.210 , Issue.8 , pp. 1635-1646
    • Pinzon-Charry, A.1    Woodberry, T.2    Kienzloe, V.3
  • 99
    • 84870796243 scopus 로고    scopus 로고
    • Transient deficiency of dendritic cells results in lack of a merozoite surface protein 1-specific CD4 T cell response during peak Plasmodium chabaudi blood-stage infection
    • Sponaas AM, Belyaev N, Falck-Hansen M, Potocnik A, Langhorne J. Transient deficiency of dendritic cells results in lack of a merozoite surface protein 1-specific CD4 T cell response during peak Plasmodium chabaudi blood-stage infection. Infect Immun 2012; 80(12): 4248-56.
    • (2012) Infect Immun , vol.80 , Issue.12 , pp. 4248-4256
    • Sponaas, A.M.1    Belyaev, N.2    Falck-Hansen, M.3    Potocnik, A.4    Langhorne, J.5
  • 100
    • 84863979534 scopus 로고    scopus 로고
    • Low-level Plasmodium falciparum blood-stage infection causes dendritic cell apoptosis and dysfunction in healthy volunteers
    • Woodberry T, Minigo G, Piera KA, et al. Low-level Plasmodium falciparum blood-stage infection causes dendritic cell apoptosis and dysfunction in healthy volunteers. J Infect Dis 2012; 206(3): 333-40.
    • (2012) J Infect Dis , vol.206 , Issue.3 , pp. 333-340
    • Woodberry, T.1    Minigo, G.2    Piera, K.A.3
  • 101
    • 34547631124 scopus 로고    scopus 로고
    • Plasmodium strain determines dendritic cell function essential for survival from malaria
    • Wykes MN, Liu XQ, Beattie L, et al. Plasmodium strain determines dendritic cell function essential for survival from malaria. PLoS Pathogens 2007; 3(7): e96.
    • (2007) PLoS Pathogens , vol.3 , Issue.7
    • Wykes, M.N.1    Liu, X.Q.2    Beattie, L.3
  • 102
    • 67249117672 scopus 로고    scopus 로고
    • B7-H1 blockade increases survival of dysfunctional CD8(+) T cells and confers protection against Leishmania donovani infections
    • Joshi T, Rodriguez S, Perovic V, Cockburn IA, Stager S. B7-H1 blockade increases survival of dysfunctional CD8(+) T cells and confers protection against Leishmania donovani infections. PLoS Pathogens 2009; 5(5): e1000431.
    • (2009) PLoS Pathogens , vol.5 , Issue.5
    • Joshi, T.1    Rodriguez, S.2    Perovic, V.3    Cockburn, I.A.4    Stager, S.5
  • 103
    • 76249106203 scopus 로고    scopus 로고
    • Regulatory B cells shape the development of Th2 immune responses in BALB/c mice infected with Leishmania major through IL-10 production
    • Ronet C, Hauyon-La Torre Y, Revaz-Breton M, et al. Regulatory B cells shape the development of Th2 immune responses in BALB/c mice infected with Leishmania major through IL-10 production. J Immunol 2010; 184(2): 886-94.
    • (2010) J Immunol , vol.184 , Issue.2 , pp. 886-894
    • Ronet, C.1    Hauyon-La Torre, Y.2    Revaz-Breton, M.3
  • 104
    • 77952708953 scopus 로고    scopus 로고
    • Assessment of CD8(+) T cell differentiation in Trypanosoma cruzi-infected children
    • Albareda MC, Olivera GC, De Rissio AM, Postan M. Assessment of CD8(+) T cell differentiation in Trypanosoma cruzi-infected children. Am J Trop Med Hyg 2010; 82(5): 861-4.
    • (2010) Am J Trop Med Hyg , vol.82 , Issue.5 , pp. 861-864
    • Albareda, M.C.1    Olivera, G.C.2    de Rissio, A.M.3    Postan, M.4
  • 105
    • 56149089459 scopus 로고    scopus 로고
    • HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease
    • Alvarez MG, Postan M, Weatherly DB, et al. HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease. PLoS Negl Trop Dis 2008; 2(9): e288.
    • (2008) PLoS Negl Trop Dis , vol.2 , Issue.9
    • Alvarez, M.G.1    Postan, M.2    Weatherly, D.B.3
  • 106
    • 70349328120 scopus 로고    scopus 로고
    • Chronic human infection with Trypanosoma cruzi drives CD4+ T cells to immune senescence
    • Albareda MC, Olivera GC, Laucella SA, et al. Chronic human infection with Trypanosoma cruzi drives CD4+ T cells to immune senescence. J Immunol 2009; 183(6): 4103-8.
    • (2009) J Immunol , vol.183 , Issue.6 , pp. 4103-4108
    • Albareda, M.C.1    Olivera, G.C.2    Laucella, S.A.3
  • 107
    • 78650933755 scopus 로고    scopus 로고
    • Phenotypic and functional profiling of malaria-induced CD8 and CD4 T cells during blood-stage infection with Plasmodium yoelii
    • Chandele A, Mukerjee P, Das G, Ahmed R, Chauhan VS. Phenotypic and functional profiling of malaria-induced CD8 and CD4 T cells during blood-stage infection with Plasmodium yoelii. Immunology 2011; 132(2): 273-86.
    • (2011) Immunology , vol.132 , Issue.2 , pp. 273-286
    • Chandele, A.1    Mukerjee, P.2    Das, G.3    Ahmed, R.4    Chauhan, V.S.5
  • 108
    • 77957059176 scopus 로고    scopus 로고
    • Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection
    • Jin HT, Anderson AC, Tan WG, et al. Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. Proc Natl Acad Sci USA 2010; 107(33): 14733-8.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.33 , pp. 14733-14738
    • Jin, H.T.1    Anderson, A.C.2    Tan, W.G.3
  • 109
    • 84879510897 scopus 로고    scopus 로고
    • Expression of Tim-1 and Tim-3 in Plasmodium berghei ANKA infection
    • Huang B, Liu M, Huang S, et al. Expression of Tim-1 and Tim-3 in Plasmodium berghei ANKA infection. Parasitol Res 2013; 112(7): 2713-9.
    • (2013) Parasitol Res , vol.112 , Issue.7 , pp. 2713-2719
    • Huang, B.1    Liu, M.2    Huang, S.3
  • 110
    • 84879550852 scopus 로고    scopus 로고
    • Upregulated expression of Tim-3 involved in the process of toxoplasmic encephalitis in mouse model
    • Wu B, Huang B, Chen Y, et al. Upregulated expression of Tim-3 involved in the process of toxoplasmic encephalitis in mouse model. Parasitol Res 2013; 112(7): 2511-21.
    • (2013) Parasitol Res , vol.112 , Issue.7 , pp. 2511-2521
    • Wu, B.1    Huang, B.2    Chen, Y.3
  • 111
    • 65549123258 scopus 로고    scopus 로고
    • Responses to malarial antigens are altered in helminth-infected children
    • Hartgers FC, Obeng BB, Kruize YC, et al. Responses to malarial antigens are altered in helminth-infected children. J Infect Dis 2009; 199(10): 1528-35.
    • (2009) J Infect Dis , vol.199 , Issue.10 , pp. 1528-1535
    • Hartgers, F.C.1    Obeng, B.B.2    Kruize, Y.C.3
  • 112
    • 38549141719 scopus 로고    scopus 로고
    • IL-10 and the resolution of infections
    • Filippi CM, von Herrath MG. IL-10 and the resolution of infections. J Pathol 2008; 214(2): 224-30.
    • (2008) J Pathol , vol.214 , Issue.2 , pp. 224-230
    • Filippi, C.M.1    von Herrath, M.G.2
  • 113
    • 84877804842 scopus 로고    scopus 로고
    • Modulation of the immune and inflammatory responses by Plasmodium falciparum schizont extracts: Role of myeloid dendritic cells in effector and regulatory functions of CD4+ lymphocytes
    • Clemente AM, Fadigati G, Caporale R, et al. Modulation of the immune and inflammatory responses by Plasmodium falciparum schizont extracts: role of myeloid dendritic cells in effector and regulatory functions of CD4+ lymphocytes. Infect Immun 2013; 81(5): 1842-51.
    • (2013) Infect Immun , vol.81 , Issue.5 , pp. 1842-1851
    • Clemente, A.M.1    Fadigati, G.2    Caporale, R.3
  • 114
    • 84879527876 scopus 로고    scopus 로고
    • T cell-derived IL-10 determines leishmaniasis disease outcome and is suppressed by a dendritic cell based vaccine
    • Schwarz T, Remer KA, Nahrendorf W, et al. T cell-derived IL-10 determines leishmaniasis disease outcome and is suppressed by a dendritic cell based vaccine. PLoS Pathogens 2013; 9(6): e1003476.
    • (2013) PLoS Pathogens , vol.9 , Issue.6
    • Schwarz, T.1    Remer, K.A.2    Nahrendorf, W.3
  • 115
    • 34547620907 scopus 로고    scopus 로고
    • SB-431542, a transforming growth factor beta inhibitor, impairs Trypanosoma cruzi infection in cardiomyocytes and parasite cycle completion
    • Waghabi MC, Keramidas M, Calvet CM, et al. SB-431542, a transforming growth factor beta inhibitor, impairs Trypanosoma cruzi infection in cardiomyocytes and parasite cycle completion. Antimicrob Agents Chemother 2007; 51(8): 2905-10.
    • (2007) Antimicrob Agents Chemother , vol.51 , Issue.8 , pp. 2905-2910
    • Waghabi, M.C.1    Keramidas, M.2    Calvet, C.M.3
  • 116
    • 84879835919 scopus 로고    scopus 로고
    • Identification of phenotypic markers of B cells from patients with Chagas disease
    • Fares RC, Correa-Oliveira R, de Araujo FF, et al. Identification of phenotypic markers of B cells from patients with Chagas disease. Parasite Immunol 2013; 35(7-8): 214-23.
    • (2013) Parasite Immunol , vol.35 , Issue.7-8 , pp. 214-223
    • Fares, R.C.1    Correa-Oliveira, R.2    de Araujo, F.F.3


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