T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis

PLoS Pathogens

Volumn 7, Issue 6, 2011, Pages

  Bockstal, Viki ^a,b,c   Guirnalda, Patrick ^a   Caljon, Guy ^b,c,d   Goenka, Radhika ^a   Telfer, Janice C ^a   Frenkel, Deborah ^a   Radwanska, Magdalena ^e   Magez, Stefan ^a,b,c   Black, Samuel J ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^e European Cooperation in Science and Technology   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIBODY; PROSTAGLANDIN RECEPTOR; TUMOR NECROSIS FACTOR; PROTOZOON ANTIBODY; VARIANT SURFACE GLYCOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; BONE MARROW; CELL MATURATION; EX VIVO STUDY; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; LYMPHOID PROGENITOR CELL; LYMPHOPOIESIS; MOUSE; NONHUMAN; SPLEEN; SPLEEN CELL; TRYPANOSOMA BRUCEI; TRYPANOSOMIASIS; AFRICAN TRYPANOSOMIASIS; ANIMAL; ANTIBODY PRODUCTION; ANTIGENIC VARIATION; C57BL MOUSE; CELL CULTURE; CYTOLOGY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM; PRE B LYMPHOCYTE;

ANIMALIA; PROTOZOA; TRYPANOSOMA BRUCEI;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIBODY FORMATION; ANTIGENIC VARIATION; APOPTOSIS; BONE MARROW; CELLS, CULTURED; IMMUNOLOGIC MEMORY; LYMPHOPOIESIS; MICE; MICE, INBRED C57BL; PRECURSOR CELLS, B-LYMPHOID; SPLEEN; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN; VARIANT SURFACE GLYCOPROTEINS, TRYPANOSOMA;

EID: 79959833610     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002089     Document Type: Article

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