B7-H1 blockade increases survival of dysfunctional CD8+ T cells and confers protection against Leishmania donovaniinfections

PLoS Pathogens

Volumn 5, Issue 5, 2009, Pages

  Joshi, Trupti ^a   Rodriguez, Susana ^a   Perovic, Vladimir ^a   Cockburn, Ian A ^b   Stäger, Simona ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 H1 ANTIGEN; LYMPHOCYTE ANTIGEN; OVALBUMIN; UNCLASSIFIED DRUG; B7 ANTIGEN; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; OVA 8; OVA-8; PDCD1LG1 PROTEIN, MOUSE; PEPTIDE; PEPTIDE FRAGMENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY BURDEN; CD8+ T LYMPHOCYTE; CELL DEATH; CELL EXPANSION; CELL INVASION; CELL SURVIVAL; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; LEISHMANIA DONOVANI; LEISHMANIASIS; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SPLEEN; TRANSGENIC ORGANISM; ANIMAL; CELL PROLIFERATION; DENDRITIC CELL; DISEASE MODEL; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MOLECULAR CLONING; PARASITOLOGY; PATHOGENICITY; SUPERINFECTION; TRANSGENIC ANIMAL; VACCINIA VIRUS; VISCERAL LEISHMANIASIS;

LEISHMANIA DONOVANI;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIGENS, CD; ANTIGENS, CD80; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CLONING, MOLECULAR; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; OVALBUMIN; PEPTIDE FRAGMENTS; PEPTIDES; SPLEEN; SUPERINFECTION; VACCINIA VIRUS;

EID: 67249117672     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000431     Document Type: Article

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