Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses

PLoS Pathogens

Volumn 4, Issue 5, 2008, Pages

  Radwanska, Magdalena ^a   Guirnalda, Patrick ^b   De Trez, Carl ^a   Ryffel, Bernard ^c   Black, Samuel ^b   Magez, Stefan ^d,e  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

^c CNRS   (France)

^d VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^e DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR RECEPTOR; B LYMPHOCYTE RECEPTOR; CASPASE 3; IMMUNOGLOBULIN M; LIPOCORTIN 5; MESSENGER RNA; PROTEIN BCL 2; PROTOZOON ANTIBODY; VACCINE;

AFRICAN TRYPANOSOMIASIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGENIC VARIATION; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BORDETELLA PERTUSSIS; CONTROLLED STUDY; CROSS LINKING; ENDEMIC DISEASE; ENZYME ACTIVITY; FLUORESCENCE ACTIVATED CELL SORTING; IMMUNE RESPONSE; IMMUNOLOGICAL MEMORY; INFECTION SENSITIVITY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; SPLEEN; TRYPANOSOMA BRUCEI; TRYPANOSOMIASIS; VACCINATION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL PROLIFERATION; DENDRITIC CELL; DISEASE MODEL; FLOW CYTOMETRY; GENE EXPRESSION; HOST PARASITE INTERACTION; IMMUNOLOGY; IMMUNOPHENOTYPING; METABOLISM; NEWBORN; PARASITOLOGY; PATHOGENICITY; PATHOLOGY;

ANIMALIA; BORDETELLA PERTUSSIS; MAMMALIA; MUS; TRYPANOSOMA BRUCEI;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, PROTOZOAN; APOPTOSIS; B-LYMPHOCYTES; CELL PROLIFERATION; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; GENE EXPRESSION; HOST-PARASITE INTERACTIONS; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; MICE; MICE, INBRED BALB C; RNA, MESSENGER; SPLEEN; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN; VACCINES;

EID: 44949219210     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000078     Document Type: Article

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