Severe malaria is associated with parasite binding to endothelial protein C receptor

Nature

Volumn 498, Issue 7455, 2013, Pages 502-505

  Turner, Louise ^a   Lavstsen, Thomas ^a   Berger, Sanne S ^a   Wang, Christian W ^a   Petersen, Jens E V ^a   Avril, Marion ^b   Brazier, Andrew J ^b   Freeth, Jim ^c   Jespersen, Jakob S ^a   Nielsen, Morten A ^a   Magistrado, Pamela ^d   Lusingu, John ^d   Smith, Joseph D ^b,e   Higgins, Matthew K ^f   Theander, Thor G ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^c Retrogenix   (United Kingdom)

^d NATIONAL INSTITUTE OF MEDICAL RESEARCH   (Tanzania)

^e UNIVERSITY OF WASHINGTON   (United States)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; APC PROTEIN; CD31 ANTIGEN; ENDOTHELIAL PROTEIN C RECEPTOR; ERYTHROCYTE MEMBRANE PROTEIN 1; MALARIA VACCINE; RECOMBINANT INTERCELLULAR ADHESION MOLECULE 1;

ANTICOAGULANT; BIOCHEMISTRY; CHEMICAL BINDING; CYTOLOGY; DISEASE CONTROL; DISEASE SEVERITY; EPIDEMIOLOGY; MALARIA; PARASITE; PATHOGENICITY; PATHOLOGY; PROTEIN; PROTOZOAN;

ARTICLE; BRAIN BLOOD VESSEL; CELL PROTECTION; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG RECEPTOR BINDING; ELECTRON SPIN RESONANCE; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; MALARIA FALCIPARUM; MICROVASCULAR ENDOTHELIAL CELL; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PUBLIC HEALTH SERVICE;

ANIMALS; ANTIGENS, CD; BLOOD COAGULATION; BRAIN; CELL ADHESION; CELL LINE; CHO CELLS; CRICETINAE; ENDOTHELIAL CELLS; ERYTHROCYTE MEMBRANE; HUMANS; INFLAMMATION; MALARIA, FALCIPARUM; MICROCIRCULATION; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RECEPTORS, CELL SURFACE;

PLASMODIUM FALCIPARUM;

EID: 84879691819     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12216     Document Type: Article

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